Protein Alignment Con and Lrrc52

DIOPT Version :10

• Sequence 1: NP_523930.3
• Gene: Con / 38590
• FlyBaseID: FBgn0005775
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_001070902.1
• Gene: Lrrc52 / 289199
• RGDID: 1312014
• Length: 314
• Species: Rattus norvegicus
• Alignment Length: 326
• Identity: 73/326 - (22%)
• Similarity: 130/326 - (39%)
• Gaps: 68/326 - (20%)

  Fly   217 NHIMALDQDAFANHIRLRELNLEHNQIFEMDRYAFRNLPL-CERLFLNNNNISTLHEGLFADMAR 280
            |:.:..||:.....::|.|...:              :|| ..||:||||.|::|.......::.
  Rat    28 NNCLCQDQEVACTDLQLTEYPTD--------------IPLNTRRLYLNNNKITSLPALQLGFLSD 78

  Fly   281 LTFLNLAHNQINVLTSEIFRGLGNLNVLKLTRNNLNFIGDTVFAELWSLSELELDDN-RIERISE 344
            |.:|:..:|:|..:....|.|:..|..|.|:.|||..|....|:.|.:|..|.:.:| .:..:.:
  Rat    79 LVYLDCQNNRIREVMDYTFIGIFKLLYLDLSSNNLTSISPFSFSILTNLVRLNISNNPHLLYLDK 143

  Fly   345 RALDGLNTLKTLNLRNNLLKKIDNGLLRGTPALLSINVQANKLETLTFYTFQPIMDNLVNSTSEL 409
            .......:|:.|:|||..::.||:   .|...|:.:..                          |
  Rat   144 YIFANTTSLRYLDLRNTGMQIIDH---TGFHHLVVLQT--------------------------L 179

  Fly   410 LVSDNKFICDCRLQWIFELKNRTRHLQLRDSLEDLHCTLQEPKLSHFVDPVPP----------TI 464
            .:|.|.:.|:|.. ..|.:.....|:...|: ::..|| :.|:|..:  |:..          |.
  Rat   180 YLSGNPWKCNCSF-LDFTIHLLVSHMDHPDA-QNATCT-EPPELKGW--PITKVGNPLQYMCITH 239

  Fly   465 LD-----VLNIGGFT--AIGSNSASMGGVGNSVVGSSYSGLTMDDSRKHLGSR-SRQALRGQRQF 521
            ||     .|.:.||.  |.|:.:|.:.||...:..::....:.||:....|:| :.|..|.....
  Rat   240 LDHQDYIFLLLIGFCIFAAGTVAAWLTGVCAVLYQNALRKSSGDDTEDETGNRITNQMFRSNTHL 304

  Fly   522 A 522
            |
  Rat   305 A 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Con	NP_523930.3	LRR	<157..459	CDD:443914	54/243 (22%)
		leucine-rich repeat	185..208	CDD:275380
		leucine-rich repeat	209..232	CDD:275380	3/14 (21%)
		leucine-rich repeat	233..256	CDD:275380	2/22 (9%)
		leucine-rich repeat	257..280	CDD:275380	8/22 (36%)
		leucine-rich repeat	281..304	CDD:275380	6/22 (27%)
		leucine-rich repeat	305..328	CDD:275380	9/22 (41%)
		leucine-rich repeat	329..352	CDD:275380	3/23 (13%)
		leucine-rich repeat	353..376	CDD:275380	8/22 (36%)
Lrrc52	NP_001070902.1	LRRNT	26..55	CDD:214470	7/40 (18%)
		leucine-rich repeat	35..54	CDD:275380	4/32 (13%)
		LRR	<43..>184	CDD:443914	41/183 (22%)
		leucine-rich repeat	56..78	CDD:275380	8/21 (38%)
		leucine-rich repeat	79..102	CDD:275380	6/22 (27%)
		leucine-rich repeat	103..126	CDD:275380	9/22 (41%)
		leucine-rich repeat	127..151	CDD:275380	3/23 (13%)
		leucine-rich repeat	152..175	CDD:275380	9/25 (36%)
		LRRCT	184..>222	CDD:214507	10/40 (25%)