| Sequence 1: | NP_523930.3 | Gene: | Con / 38590 | FlyBaseID: | FBgn0005775 | Length: | 691 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_056428.1 | Gene: | LRIT1 / 26103 | HGNCID: | 23404 | Length: | 623 | Species: | Homo sapiens |
| Alignment Length: | 444 | Identity: | 98/444 - (22%) |
|---|---|---|---|
| Similarity: | 142/444 - (31%) | Gaps: | 128/444 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 308 LKLTRNNLNFIGDTVFAELWSLSELELDDNRIERISERALDGLNTLKTLNLRNNLLKKIDNGLLR 372
Fly 373 GTPALLSINVQANK-----------LETLTFYTFQPIMDNLVNSTSELLVS-------------- 412
Fly 413 --------DNKFICDCRLQWIFELKNRTRHLQLRDSLEDLHCTLQEPKLSHFVDPVPPTILDVLN 469
Fly 470 IGGFTAIGSNSASMGGVGNSVVGSSYSGLTMDDSRK------HLGSRS-RQALRGQRQFASSAEN 527
Fly 528 VVESKMRRRRKRQEEVKEKDLAAVAPAHKRYDYYDDNNGGMSLG-----HGLDLDDNLSLHKQGF 587
Fly 588 YGAGSPVVGHNDVDVLM------TSHSASGDAL--------DILTTKNAIYIKLF--LLKPEMLP 636
Fly 637 CHDEL-SDPTELPLSRDLMDVRSNVGQDMSTAGANSLAQGMTII------VSLV 683 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Con | NP_523930.3 | LRR | <157..459 | CDD:443914 | 43/183 (23%) |
| leucine-rich repeat | 185..208 | CDD:275380 | |||
| leucine-rich repeat | 209..232 | CDD:275380 | |||
| leucine-rich repeat | 233..256 | CDD:275380 | |||
| leucine-rich repeat | 257..280 | CDD:275380 | |||
| leucine-rich repeat | 281..304 | CDD:275380 | |||
| leucine-rich repeat | 305..328 | CDD:275380 | 5/19 (26%) | ||
| leucine-rich repeat | 329..352 | CDD:275380 | 7/22 (32%) | ||
| leucine-rich repeat | 353..376 | CDD:275380 | 7/22 (32%) | ||
| LRIT1 | NP_056428.1 | LRR 1 | 60..81 | 4/16 (25%) | |
| leucine-rich repeat | 61..84 | CDD:275378 | 5/19 (26%) | ||
| LRR | <63..>174 | CDD:443914 | 30/111 (27%) | ||
| LRR 2 | 84..105 | 5/20 (25%) | |||
| leucine-rich repeat | 85..132 | CDD:275378 | 14/46 (30%) | ||
| LRR 3 | 108..129 | 6/20 (30%) | |||
| LRR 4 | 132..153 | 4/20 (20%) | |||
| leucine-rich repeat | 133..156 | CDD:275378 | 5/22 (23%) | ||
| LRR 5 | 156..177 | 6/22 (27%) | |||
| leucine-rich repeat | 157..180 | CDD:275378 | 8/24 (33%) | ||
| leucine-rich repeat | 181..205 | CDD:275378 | 2/23 (9%) | ||
| LRRCT | 201..>240 | CDD:214507 | 14/77 (18%) | ||
| IG_like | 267..345 | CDD:214653 | 20/93 (22%) | ||
| Ig strand B | 271..275 | CDD:409353 | 0/3 (0%) | ||
| Ig strand C | 284..288 | CDD:409353 | 1/3 (33%) | ||
| Ig strand E | 308..312 | CDD:409353 | 0/3 (0%) | ||
| Ig strand F | 325..330 | CDD:409353 | 1/4 (25%) | ||
| Ig strand G | 338..341 | CDD:409353 | 1/7 (14%) | ||
| FN3 | 431..498 | CDD:214495 | 4/17 (24%) | ||
| LRR 6. /evidence=ECO:0000305 | 571..594 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||