DRSC/TRiP Functional Genomics Resources

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Protein Alignment Con and Elfn1

DIOPT Version :9

Sequence 1:NP_001246635.1 Gene:Con / 38590 FlyBaseID:FBgn0005775 Length:691 Species:Drosophila melanogaster
Sequence 2:NP_001371115.1 Gene:Elfn1 / 243312 MGIID:2442479 Length:828 Species:Mus musculus


Alignment Length:228 Identity:57/228 - (25%)
Similarity:89/228 - (39%) Gaps:49/228 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   284 LNLAHNQINVLTSEIFRGLGNLNVLKLTRNNLNFIGDTVFAELWSLSELELDDNRIERISERALD 348
            |.|..|:|..:........|||..|.||:|.:.:|.|..|:..::|..|:|..||:..::|..|.
Mouse    65 LRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLR 129

  Fly   349 GLNTLKTLNLRNNLLKKIDNGLLRGTPALLSINVQANKLETLTFYTFQPIMDNLVNSTSELLVSD 413
            ||:.|:.|.|:.||::.:........|.:::|::..|:::.|...||..:     ...|...:..
Mouse   130 GLSKLEYLYLQANLIEVVMASAFWECPNIVNIDLSMNRIQQLGSGTFAGL-----TKLSVCEIYS 189

  Fly   414 NKFICDCR----LQWIFELKNRT-----------------------RHLQLRDSLEDLH--CT-- 447
            |.|.|.|.    |:|:....|.|                       ||...|..|..|.  ||  
Mouse   190 NPFYCSCELLGFLRWLAAFTNATQTHDRVQCESPPVYAGYFLLGQGRHGHQRSILSKLQSVCTEG 254

  Fly   448 ------LQEPK-------LSHFVDPVPPTILDV 467
                  |..|:       ..|...|.||...|:
Mouse   255 SYTAEVLGPPRPVPGRSQPGHSPPPPPPEPSDM 287

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ConNP_001246635.1 LRR_RI <147..291 CDD:238064 3/6 (50%)
LRR_8 183..243 CDD:290566
leucine-rich repeat 185..208 CDD:275380
leucine-rich repeat 209..232 CDD:275380
LRR_RI <225..416 CDD:238064 36/131 (27%)
LRR_8 232..291 CDD:290566 3/6 (50%)
leucine-rich repeat 233..256 CDD:275380
leucine-rich repeat 257..280 CDD:275380
leucine-rich repeat 281..304 CDD:275380 4/19 (21%)
LRR_8 304..363 CDD:290566 22/58 (38%)
leucine-rich repeat 305..328 CDD:275380 8/22 (36%)
leucine-rich repeat 329..352 CDD:275380 9/22 (41%)
LRR_8 352..416 CDD:290566 13/63 (21%)
leucine-rich repeat 353..376 CDD:275380 5/22 (23%)
LRRCT 414..>450 CDD:214507 16/72 (22%)
Elfn1NP_001371115.1 LRR 1 61..82 4/16 (25%)
leucine-rich repeat 65..85 CDD:275378 4/19 (21%)
LRR_8 85..144 CDD:404697 22/58 (38%)
LRR 2 85..106 9/20 (45%)
leucine-rich repeat 86..109 CDD:275378 8/22 (36%)
LRR 3 109..130 7/20 (35%)
leucine-rich repeat 110..133 CDD:275378 9/22 (41%)
LRR_8 132..182 CDD:404697 11/54 (20%)
LRR 4 133..154 5/20 (25%)
leucine-rich repeat 134..157 CDD:275378 5/22 (23%)
LRR 5 157..178 5/20 (25%)
leucine-rich repeat 158..171 CDD:275378 2/12 (17%)
LRRCT 190..>228 CDD:214507 8/37 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 258..293 7/30 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 627..674
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 697..731
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167831246
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.840

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