Protein Alignment Con and Lrit3

DIOPT Version :10

• Sequence 1: NP_523930.3
• Gene: Con / 38590
• FlyBaseID: FBgn0005775
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_001274153.1
• Gene: Lrit3 / 242235
• MGIID: 2685267
• Length: 681
• Species: Mus musculus
• Alignment Length: 257
• Identity: 64/257 - (24%)
• Similarity: 102/257 - (39%)
• Gaps: 57/257 - (22%)

  Fly   254 LPLCERLFLN----NNNISTLHEGLFADMARLTFLNLAHNQINVLTSEIFRGLGNLNVLKLTRNN 314
            |.||..|.:|    |..:.|            :.|.:....:..|.:|.|..|..|..|.|..|:
Mouse    40 LVLCNDLDMNEVPANFPVDT------------SKLRIEKTVVRRLPAEAFYYLVELQYLWLAYNS 92

  Fly   315 LNFIGDTVFAELWSLSELELDDNRIERISERALDGLNTLKTLNLRNNLLKKIDNGLLRGTPALLS 379
            :..|..:.|..|..|.||.||.|.:......:|..:..|:||:|.||.:..:.|..:|....|..
Mouse    93 VASIETSSFYNLRQLHELRLDGNSLTAFPWVSLLDMPHLRTLDLHNNRIASVPNEAVRYLRNLTC 157

  Fly   380 INVQANKLETLTFYTFQPIMDNLVNSTSELLVS-----------------DNKFICDCRLQWIFE 427
            :::.:|:|.||.        .:.::|.|.|.|:                 ||.:.|||.:..:.|
Mouse   158 LDLSSNRLTTLP--------PDFLDSWSHLAVTPSRSPDFPPRRIILGLQDNPWFCDCHISKVIE 214

  Fly   428 LKNRTRH-LQLRDSLEDLHCT---------LQEPKLSHFVDPVPPTILDVLNIGGFTAIGSN 479
            |...|.| :.|.|.|  :.|:         .|..:|...:.  |..::....|  .:|:|||
Mouse   215 LSKVTDHAVVLLDPL--MVCSEPERFQGILFQRVELEKCLK--PSVMMSATKI--TSALGSN 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Con	NP_523930.3	LRR	<157..459	CDD:443914	58/235 (25%)
		leucine-rich repeat	185..208	CDD:275380
		leucine-rich repeat	209..232	CDD:275380
		leucine-rich repeat	233..256	CDD:275380	1/1 (100%)
		leucine-rich repeat	257..280	CDD:275380	5/26 (19%)
		leucine-rich repeat	281..304	CDD:275380	5/22 (23%)
		leucine-rich repeat	305..328	CDD:275380	7/22 (32%)
		leucine-rich repeat	329..352	CDD:275380	7/22 (32%)
		leucine-rich repeat	353..376	CDD:275380	8/22 (36%)
Lrit3	NP_001274153.1	LRR 1. /evidence=ECO:0000255	56..79		5/34 (15%)
		LRR	<61..>170	CDD:443914	32/116 (28%)
		LRR 2. /evidence=ECO:0000255	80..103		7/22 (32%)
		leucine-rich repeat	83..106	CDD:275378	7/22 (32%)
		LRR 3. /evidence=ECO:0000255	104..128		8/23 (35%)
		leucine-rich repeat	107..130	CDD:275378	7/22 (32%)
		LRR 4. /evidence=ECO:0000255	129..151		7/21 (33%)
		leucine-rich repeat	131..154	CDD:275378	8/22 (36%)
		LRR 5. /evidence=ECO:0000255	152..175		5/30 (17%)
		leucine-rich repeat	155..168	CDD:275378	3/12 (25%)
		Ig_3	253..332	CDD:464046	6/22 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	350..391
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	425..464
		FN3	489..563	CDD:238020