DRSC/TRiP Functional Genomics Resources

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Protein Alignment Con and Lrrc52

DIOPT Version :9

Sequence 1:NP_001246635.1 Gene:Con / 38590 FlyBaseID:FBgn0005775 Length:691 Species:Drosophila melanogaster
Sequence 2:NP_001013400.1 Gene:Lrrc52 / 240899 MGIID:1924118 Length:314 Species:Mus musculus


Alignment Length:313 Identity:75/313 - (23%)
Similarity:123/313 - (39%) Gaps:67/313 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   217 NHIMALDQDAFANHIRLRELNLEHNQIFEMDRYAFRNLPL-CERLFLNNNNISTLHEGLFADMAR 280
            |..:..||:.....:.|.|...:              :|| ..||:||||.|::|.......::.
Mouse    28 NKCVCQDQEVACIDLHLTEYPAD--------------IPLNTRRLYLNNNKITSLPALQLGFLSD 78

  Fly   281 LTFLNLAHNQINVLTSEIFRGLGNLNVLKLTRNNLNFIGDTVFAELWSLSELELDDN-RIERISE 344
            |.:|:..:|:|..:....|.|:..|..|.|:.|||..|....|:.|.:|..|.:..| .:..:.:
Mouse    79 LVYLDCQNNRIREVMDYTFIGIFRLIYLDLSSNNLTSISPFSFSVLTNLVRLNISHNPHLLYLDK 143

  Fly   345 RALDGLNTLKTLNLRNNLLKKID-NGLLRGTPALLSINVQANKLETLTFYTFQPIMDNLVNSTSE 408
            .......:|:.|:|||..|..|| ||.              :.|..|                ..
Mouse   144 YVFANTTSLRYLDLRNTGLHIIDHNGF--------------HHLVVL----------------QT 178

  Fly   409 LLVSDNKFICDCRLQWIFELKNRTRHLQLRDSLEDLHCTLQEP---------KLSHFVDPVPPTI 464
            |.:|.|.:||:|.. ..|.:.....|:...|: ::..||  ||         |:.:.:..:..|.
Mouse   179 LYLSGNPWICNCSF-LDFTIHLLVSHMDHPDA-QNATCT--EPAELKGWPITKVGNPLQYMCITH 239

  Fly   465 LD-----VLNIGGFT--AIGSNSASMGGVGNSVVGSSYSGLTMDDSRKHLGSR 510
            ||     .|.:.||.  |.|:.:|.:.||...:..::....:.||:....|||
Mouse   240 LDQQDYIFLLLIGFCIFAAGTVAAWLTGVCAVLYQNALRTSSGDDTEDETGSR 292

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ConNP_001246635.1 LRR_RI <147..291 CDD:238064 18/74 (24%)
LRR_8 183..243 CDD:290566 5/25 (20%)
leucine-rich repeat 185..208 CDD:275380
leucine-rich repeat 209..232 CDD:275380 3/14 (21%)
LRR_RI <225..416 CDD:238064 45/193 (23%)
LRR_8 232..291 CDD:290566 15/59 (25%)
leucine-rich repeat 233..256 CDD:275380 2/22 (9%)
leucine-rich repeat 257..280 CDD:275380 8/22 (36%)
leucine-rich repeat 281..304 CDD:275380 6/22 (27%)
LRR_8 304..363 CDD:290566 17/59 (29%)
leucine-rich repeat 305..328 CDD:275380 9/22 (41%)
leucine-rich repeat 329..352 CDD:275380 3/23 (13%)
LRR_8 352..416 CDD:290566 15/64 (23%)
leucine-rich repeat 353..376 CDD:275380 10/23 (43%)
LRRCT 414..>450 CDD:214507 9/35 (26%)
Lrrc52NP_001013400.1 leucine-rich repeat 35..54 CDD:275380 4/32 (13%)
LRR 1 54..73 8/18 (44%)
leucine-rich repeat 56..78 CDD:275380 8/21 (38%)
LRR 2 78..99 5/20 (25%)
LRR_8 79..136 CDD:316378 17/56 (30%)
leucine-rich repeat 79..102 CDD:275380 6/22 (27%)
LRR 3 102..123 8/20 (40%)
leucine-rich repeat 103..126 CDD:275380 9/22 (41%)
LRR_8 125..185 CDD:316378 17/89 (19%)
LRR 4 126..148 3/21 (14%)
leucine-rich repeat 127..151 CDD:275380 3/23 (13%)
LRR 5 151..172 10/34 (29%)
leucine-rich repeat 152..175 CDD:275380 11/36 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167831254
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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