DRSC/TRiP Functional Genomics Resources

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Protein Alignment Con and Elfn2

DIOPT Version :9

Sequence 1:NP_001246635.1 Gene:Con / 38590 FlyBaseID:FBgn0005775 Length:691 Species:Drosophila melanogaster
Sequence 2:NP_001345621.1 Gene:Elfn2 / 207393 MGIID:3608416 Length:823 Species:Mus musculus


Alignment Length:224 Identity:61/224 - (27%)
Similarity:104/224 - (46%) Gaps:33/224 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   252 RNLPLCERLFLNNNNISTLHEGLFADMARLTFLNLAHNQINVLTSEIFRGLGNLNVLKLTRNNLN 316
            :|.|..|.:..:.|  ||:|:           |.|..|::..:........|||..|.||:|.::
Mouse    41 QNQPPYETIPQHIN--STVHD-----------LRLNENKLKAVLYSSLNRFGNLTDLNLTKNEIS 92

  Fly   317 FIGDTVFAELWSLSELELDDNRIERISERALDGLNTLKTLNLRNNLLKKIDNGLLRGTPALLSIN 381
            :|.|..|....||..|:|..||:..::|..|.|::.|:.|.:::||::.:........|:|:||:
Mouse    93 YIEDGAFLGQTSLQVLQLGYNRLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISID 157

  Fly   382 VQANKLETLTFYTFQPIMDNLVNSTSELLVSD---NKFICDCR----LQWIFELKNRTRH---LQ 436
            :.:|:|..|...||.        |.:.|:|.:   |.|.|:|.    |.|:....|.|::   ||
Mouse   158 LSSNRLSRLDGATFA--------SLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQ 214

  Fly   437 LRDSLEDLHCTLQEPKLSHFVDPVPPTIL 465
            .....|.....|..|:..|.::.:  |:|
Mouse   215 CESPREFAGYPLLVPRPYHSLNAI--TVL 241

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ConNP_001246635.1 LRR_RI <147..291 CDD:238064 10/38 (26%)
LRR_8 183..243 CDD:290566
leucine-rich repeat 185..208 CDD:275380
leucine-rich repeat 209..232 CDD:275380
LRR_RI <225..416 CDD:238064 46/166 (28%)
LRR_8 232..291 CDD:290566 10/38 (26%)
leucine-rich repeat 233..256 CDD:275380 1/3 (33%)
leucine-rich repeat 257..280 CDD:275380 5/22 (23%)
leucine-rich repeat 281..304 CDD:275380 3/22 (14%)
LRR_8 304..363 CDD:290566 21/58 (36%)
leucine-rich repeat 305..328 CDD:275380 8/22 (36%)
leucine-rich repeat 329..352 CDD:275380 8/22 (36%)
LRR_8 352..416 CDD:290566 17/66 (26%)
leucine-rich repeat 353..376 CDD:275380 4/22 (18%)
LRRCT 414..>450 CDD:214507 12/42 (29%)
Elfn2NP_001345621.1 LRR 1 56..77 5/31 (16%)
leucine-rich repeat 60..80 CDD:275378 3/19 (16%)
LRR_8 80..139 CDD:404697 21/58 (36%)
LRR 2 80..101 9/20 (45%)
leucine-rich repeat 81..104 CDD:275378 8/22 (36%)
LRR 3 104..125 8/20 (40%)
leucine-rich repeat 105..128 CDD:275378 8/22 (36%)
LRR_8 127..187 CDD:404697 17/67 (25%)
LRR 4 128..149 4/20 (20%)
leucine-rich repeat 129..152 CDD:275378 4/22 (18%)
LRR 5 152..173 8/28 (29%)
leucine-rich repeat 153..166 CDD:275378 5/12 (42%)
PCC 157..>227 CDD:188093 19/77 (25%)
leucine-rich repeat 177..189 CDD:275378 4/11 (36%)
leucine-rich repeat 200..226 CDD:275380 5/25 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 249..294
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 590..624
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167831260
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.840

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