DRSC/TRiP Functional Genomics Resources

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Protein Alignment Con and sma-10

DIOPT Version :9

Sequence 1:NP_001246635.1 Gene:Con / 38590 FlyBaseID:FBgn0005775 Length:691 Species:Drosophila melanogaster
Sequence 2:NP_499896.1 Gene:sma-10 / 176849 WormBaseID:WBGene00020649 Length:881 Species:Caenorhabditis elegans


Alignment Length:315 Identity:74/315 - (23%)
Similarity:130/315 - (41%) Gaps:62/315 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   171 LDYIPTMIIEPLKNLSSIVIEYSQVEIVKSYAFANLPFLERIILNNNHIMALDQDAFANHIRLRE 235
            :.|:|........|:..:.:..:.:..:.:..|::...|..:.|..|||..|:|.:|:...:|..
 Worm   159 ISYLPKPTTSAKVNIEKLDLASNSITDIGTDHFSSFNTLVTLKLARNHITTLNQFSFSRLRKLES 223

  Fly   236 LNLEHNQIFEMDRYAFRNLPLCERLFLNNNNISTLHEGLFADMARLTFLNLAHNQINVLTSEIFR 300
            |:|..|.|.|:...||..||..:.:.|..|::..|.:|:|.....|..|||:.|::..:|.....
 Worm   224 LDLTRNMIREVRFLAFNQLPSLQNVSLARNDVYRLDDGMFYACEGLKHLNLSTNRVQAVTEGWMF 288

  Fly   301 GLGNLNVLKLT------------------------RNNLNFIGDTVFAELWSLSELELDDNRIER 341
            ||.:|.||.|:                        .|.:..:....|..|..|.||.|..|.|:.
 Worm   289 GLTSLEVLDLSYNQIQSFHISSWSHTPKLKWLSLHSNRIQSLPSGSFRVLRQLEELILSANSIDS 353

  Fly   342 ISERALDGLNTLKTLNLRNNLLKKI--DNGLLRGT--------------------------PALL 378
            :.:.||.|:::|..|:|.:|.|...  |..:|..|                          |||.
 Worm   354 LHKFALVGMSSLHKLDLSSNTLAVCVEDGAVLYNTSMPFLRSLRFTNNQLRVIPKRAFERFPALE 418

  Fly   379 SINVQANKLETLTFYTFQPIMDNLVNSTSELLVSDNKFICDCRL----QWIFELK 429
            .:::..|.:.|:....|:|:      ....|:::.:..:|||::    .||:.||
 Worm   419 ELDLTDNPIATIHPEAFEPL------ELKRLVMNSSSILCDCQISWLASWIYRLK 467

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ConNP_001246635.1 LRR_RI <147..291 CDD:238064 32/119 (27%)
LRR_8 183..243 CDD:290566 14/59 (24%)
leucine-rich repeat 185..208 CDD:275380 1/22 (5%)
leucine-rich repeat 209..232 CDD:275380 8/22 (36%)
LRR_RI <225..416 CDD:238064 56/242 (23%)
LRR_8 232..291 CDD:290566 20/58 (34%)
leucine-rich repeat 233..256 CDD:275380 9/22 (41%)
leucine-rich repeat 257..280 CDD:275380 5/22 (23%)
leucine-rich repeat 281..304 CDD:275380 8/22 (36%)
LRR_8 304..363 CDD:290566 20/82 (24%)
leucine-rich repeat 305..328 CDD:275380 7/46 (15%)
leucine-rich repeat 329..352 CDD:275380 9/22 (41%)
LRR_8 352..416 CDD:290566 16/91 (18%)
leucine-rich repeat 353..376 CDD:275380 8/50 (16%)
LRRCT 414..>450 CDD:214507 7/20 (35%)
sma-10NP_499896.1 LRRNT 29..54 CDD:214470
leucine-rich repeat 55..77 CDD:275380
LRR_8 78..135 CDD:290566
LRR_4 78..116 CDD:289563
leucine-rich repeat 78..101 CDD:275380
LRR_RI 100..303 CDD:238064 39/143 (27%)
leucine-rich repeat 102..124 CDD:275380
leucine-rich repeat 125..148 CDD:275380
leucine-rich repeat 149..172 CDD:275380 2/12 (17%)
LRR_8 172..231 CDD:290566 14/58 (24%)
leucine-rich repeat 173..196 CDD:275380 1/22 (5%)
leucine-rich repeat 197..220 CDD:275380 8/22 (36%)
leucine-rich repeat 221..244 CDD:275380 9/22 (41%)
LRR_8 243..303 CDD:290566 18/59 (31%)
leucine-rich repeat 245..268 CDD:275380 5/22 (23%)
LRR_RI 269..453 CDD:238064 40/189 (21%)
leucine-rich repeat 269..292 CDD:275380 8/22 (36%)
leucine-rich repeat 293..316 CDD:275380 4/22 (18%)
LRR_8 315..373 CDD:290566 15/57 (26%)
leucine-rich repeat 317..340 CDD:275380 3/22 (14%)
leucine-rich repeat 341..364 CDD:275380 9/22 (41%)
leucine-rich repeat 365..392 CDD:275380 8/26 (31%)
LRR_8 393..450 CDD:290566 8/62 (13%)
leucine-rich repeat 393..416 CDD:275380 0/22 (0%)
leucine-rich repeat 417..438 CDD:275380 4/20 (20%)
I-set 506..612 CDD:254352
Ig 522..606 CDD:143165
I-set 616..705 CDD:254352
Ig 633..705 CDD:299845
Ig 716..786 CDD:299845
IG 719..788 CDD:214652
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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