Protein Alignment Con and pan-1

DIOPT Version :10

• Sequence 1: NP_523930.3
• Gene: Con / 38590
• FlyBaseID: FBgn0005775
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_497925.1
• Gene: pan-1 / 175596
• WormBaseID: WBGene00003915
• Length: 594
• Species: Caenorhabditis elegans
• Alignment Length: 312
• Identity: 83/312 - (26%)
• Similarity: 139/312 - (44%)
• Gaps: 51/312 - (16%)

  Fly   152 FYQQKRLRELKFVIQNNARLDYIPTMIIEPLKNLSSIVIEYSQVEIVKSYAFANLPFLERIILNN 216
            |.:.|::.|| .:.:|:.|:  :.|...:.:|||..:.::...:||::..||..|..||::||:|
 Worm   171 FEELKKVEEL-LLNENDIRV--LKTGTFDGMKNLKKLTLQNCNLEIIQKGAFRGLNSLEQLILSN 232

  Fly   217 NHIMALDQDAFANHIRLRELNLEHNQIFEMDRYAFRNLPLCERLFLNNNNISTLHEGLFADMARL 281
            |::..:|...|:....||.|:|..|:|..::..:|   |..|:|.||||.|.::......|:..|
 Worm   233 NNLENIDWTIFSALKNLRVLDLGSNKISNVEMKSF---PKLEKLVLNNNTIDSMKSIKLKDLPSL 294

  Fly   282 TFLNLAHNQINVLTSEIFRGL---GNLNVLKLTRNNLNFIGDTVFAELWSLSELELDDNRIERIS 343
            .......|:|..:......||   ..:..|.|.||||:.|....|....:|..|.|..|:||.:|
 Worm   295 VVALFDRNKIESIGDMDMFGLTRSDRIETLSLARNNLSQISPKAFQHTPNLITLLLQYNQIEELS 359

  Fly   344 ERALDGLNT------------------------------LKTLNLRNNLLKKIDNGLLRGTPALL 378
            ..:...:.|                              |.:|.|.:|::.||:...|.|. .:.
 Worm   360 SHSPSQVRTPFLASLKKLVTLQLSSNNLSVIRSDELPKSLSSLALDHNVISKIEARALEGM-EIK 423

  Fly   379 SINVQANKLETL---TFYTFQPIMDNLVNSTSELLVSDNKFICDCR--LQWI 425
            .:.:.:|||..|   ||.:|.|      .|...:.||.|.::|.|.  .:|:
 Worm   424 RLYLHSNKLNYLYQGTFDSFSP------KSVEAVDVSLNPWVCVCNDPKEWL 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Con	NP_523930.3	LRR	<157..459	CDD:443914	81/307 (26%)
		leucine-rich repeat	185..208	CDD:275380	6/22 (27%)
		leucine-rich repeat	209..232	CDD:275380	8/22 (36%)
		leucine-rich repeat	233..256	CDD:275380	7/22 (32%)
		leucine-rich repeat	257..280	CDD:275380	8/22 (36%)
		leucine-rich repeat	281..304	CDD:275380	5/25 (20%)
		leucine-rich repeat	305..328	CDD:275380	8/22 (36%)
		leucine-rich repeat	329..352	CDD:275380	7/22 (32%)
		leucine-rich repeat	353..376	CDD:275380	8/22 (36%)
pan-1	NP_497925.1	leucine-rich repeat	81..104	CDD:275380
		leucine-rich repeat	105..128	CDD:275380
		leucine-rich repeat	130..152	CDD:275380
		LRR_8	132..187	CDD:404697	5/16 (31%)
		leucine-rich repeat	153..176	CDD:275380	1/4 (25%)
		LRR	163..>418	CDD:443914	66/252 (26%)
		leucine-rich repeat	177..200	CDD:275380	5/25 (20%)
		leucine-rich repeat	201..224	CDD:275380	6/22 (27%)
		leucine-rich repeat	225..248	CDD:275380	8/22 (36%)
		leucine-rich repeat	249..269	CDD:275380	7/22 (32%)
		leucine-rich repeat	270..293	CDD:275380	8/22 (36%)
		leucine-rich repeat	294..320	CDD:275380	5/25 (20%)
		leucine-rich repeat	321..344	CDD:275380	8/22 (36%)
		leucine-rich repeat	377..398	CDD:275380	0/20 (0%)
		leucine-rich repeat	399..420	CDD:275380	7/20 (35%)
		leucine-rich repeat	423..442	CDD:275380	6/18 (33%)