Protein Alignment Con and Elfn2

DIOPT Version :10

• Sequence 1: NP_523930.3
• Gene: Con / 38590
• FlyBaseID: FBgn0005775
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_001419157.1
• Gene: Elfn2 / 100910536
• RGDID: 1559693
• Length: 820
• Species: Rattus norvegicus
• Alignment Length: 687
• Identity: 140/687 - (20%)
• Similarity: 211/687 - (30%)
• Gaps: 262/687 - (38%)

  Fly   107 GFCTRRRDMKLMCYCTPDENHVPVQKAECWVFSEGLHQNDTTWTRFYQQKRLRELKFVIQNNARL 171
            |.|.    ..|:|.|.|...|     |:||:. ||  .....|           |....||....
  Rat     5 GLCA----AALLCVCQPGAVH-----ADCWLI-EG--DKGYVW-----------LAICSQNQPPY 46

  Fly   172 DYIPTMIIEPLKNLSSIVIEYSQVEIVKSYAFANLPFLERIILNNNHIMALDQDAFANHIRLREL 236
            :.||..|...:.:|.                           ||.|.:.|:...:......|.:|
  Rat    47 ETIPQHINSTVHDLR---------------------------LNENKLKAVLYSSLNRFGNLTDL 84

  Fly   237 NLEHNQIFEMDRYAFRNLPLCERLFLNNNNISTLHEGLFADMARLTFLNLAHNQINVLTSEIFRG 301
            ||..|:|..::..||......:.|.|..|.:|.|.||:...|:||.||.:.||.|.|:|...|..
  Rat    85 NLTKNEISYIEDGAFLGQTSLQVLQLGYNRLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSE 149

  Fly   302 LGNLNVLKLTRNNLNFIGDTVFAELWSLSELELDDN--------------------------RIE 340
            ..:|..:.|:.|.|:.:....||.|.||...||..|                          |::
  Rat   150 CPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQ 214

  Fly   341 RISERALDGLNTL-----KTLNLRNNLLKKIDNGLLRGTPA------------------------ 376
            ..|.|...|...|     .:||....|..|..||.:...|.
  Rat   215 CESPREFAGYPLLVPRPYHSLNAITVLQAKCRNGSMPARPVSHPTPYSTDAQREPDENSGFNPDE 279

  Fly   377 LLSINVQAN-----------KLETLTF--YTFQPIMDNLVNSTSELLVSDNKFICDCRLQWIFEL 428
            :||:...|:           ||..:||  .|...|:.:..:....|:..:|.:..|     :..|
  Rat   280 ILSVEPPASSTTDASAGPAIKLHQVTFTSATLVVIIPHPYSKMYVLVQYNNSYFSD-----VMTL 339

  Fly   429 KNRTRHL---QLRDSLEDLHCTL---QEPKLSHFV-----------DPVPPTILDVLNIGGFTAI 476
            ||:...:   :||...|...|..   ...:.:|..           |.||.|......|  .|.:
  Rat   340 KNKKEIVTLDKLRAHTEYTFCVTSLRNSRRFNHTCLTFTTRDLVPGDQVPSTSTTTHYI--MTIL 402

  Fly   477 GSNSASMGGVGNSVVGSSYSGLTMDDSRKHLGSRSRQALRGQRQFASSAENVVESKMRRRRKRQE 541
            |   ...|.|  .|:|:.|..|                                   |:||.::|
  Rat   403 G---CLFGMV--IVLGAVYYCL-----------------------------------RKRRMQEE 427

  Fly   542 EVKEKDLAAVAPAHKRYDYYDDNNGGMSLGHGLDLDDNLSLHKQGFYGAGSPVVGHNDVDVLMTS 606
            :.|..::....               :.:.:|.|:|            |||.|
  Rat   428 QQKSVNVKKTI---------------LEMRYGADVD------------AGSIV------------ 453

  Fly   607 HSASGDALDILTTKNAIYIKLFLLKPEMLPCHDELSDPT----ELPLSRDL--------MDVRSN 659
            |:|..                 |::|.:||.....|.|:    :||.|:.|        :..:.|
  Rat   454 HAAQK-----------------LVEPPVLPVARMSSIPSMIGEKLPASKGLEAGLDTPKVATKGN 501

  Fly   660 VGQDMSTAGANSLA------------QGMTIIVSLVA 684
            ..:..:.|..:|||            ||....:|.:|
  Rat   502 YIEVRTGAAGDSLARPEDDLPEIENGQGSAAEISTIA 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Con	NP_523930.3	LRR	<157..459	CDD:443914	81/386 (21%)
		leucine-rich repeat	185..208	CDD:275380	1/22 (5%)
		leucine-rich repeat	209..232	CDD:275380	4/22 (18%)
		leucine-rich repeat	233..256	CDD:275380	8/22 (36%)
		leucine-rich repeat	257..280	CDD:275380	8/22 (36%)
		leucine-rich repeat	281..304	CDD:275380	9/22 (41%)
		leucine-rich repeat	305..328	CDD:275380	7/22 (32%)
		leucine-rich repeat	329..352	CDD:275380	8/48 (17%)
		leucine-rich repeat	353..376	CDD:275380	7/27 (26%)
Elfn2	NP_001419157.1	LRR	<60..>205	CDD:443914	43/171 (25%)
		leucine-rich repeat	60..80	CDD:275378	5/46 (11%)
		leucine-rich repeat	81..104	CDD:275378	8/22 (36%)
		leucine-rich repeat	105..128	CDD:275378	8/22 (36%)
		leucine-rich repeat	129..152	CDD:275378	9/22 (41%)
		leucine-rich repeat	153..166	CDD:275378	4/12 (33%)
		leucine-rich repeat	177..189	CDD:275378	4/11 (36%)
		leucine-rich repeat	200..226	CDD:275380	4/25 (16%)