DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Con and lrrtm2

DIOPT Version :9

Sequence 1:NP_001246635.1 Gene:Con / 38590 FlyBaseID:FBgn0005775 Length:691 Species:Drosophila melanogaster
Sequence 2:NP_001338621.1 Gene:lrrtm2 / 100538061 ZFINID:ZDB-GENE-080327-8 Length:542 Species:Danio rerio


Alignment Length:482 Identity:110/482 - (22%)
Similarity:173/482 - (35%) Gaps:143/482 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   214 LNNNHIMALDQDAFANHIRLRELNLEHNQIFEMDRYAFRNLPLCERLFLNNNNISTLHEGLFADM 278
            |.:|.|..|..|.|....:|..|:|:||||..:...||:.|...:.|.|::|.|:.|....|..:
Zfish    68 LRHNSISELSSDQFFGFTQLTWLHLDHNQITTVHEDAFQGLYKLKDLNLSSNRITKLPNTTFIHL 132

  Fly   279 ARLTFLNLAHNQINVLTSEIFRGLGNLNVLKLTRNNLNFIGDTVFAELWSLSELELDDNRIERIS 343
            ..|..|:|:.||:..|..|:|.||..|.:|.|..|:|.......|.:..||..|.|.:||:..::
Zfish   133 INLQILDLSFNQMTALEPELFHGLRKLQILHLRSNSLRTTPVRAFWDCRSLEYLGLSNNRLRSLA 197

  Fly   344 ERALDGLNTLKTLNLRNNLLKKIDNGLLRGTPALLSINVQANKLETLT----------------- 391
            .....||..|:.|:|.:|.|.||:........||..:.:|.||:..||                 
Zfish   198 RNGFAGLIKLRELHLEHNHLTKINLAHFPRLVALQFLYLQWNKINNLTSTMEWKWTTLEKLDLTG 262

  Fly   392 ----------FYTFQP----IMDN--LVNSTSELL----------VSDNKFICDCRL----QWIF 426
                      |.|...    ::||  |.|..|:.:          :|.|.:.|..|:    .|:.
Zfish   263 NEIRVLIPEVFETLPSLKILLLDNNKLSNLDSQTMDMWKSLNVIGLSSNLWECTKRICNLATWLS 327

  Fly   427 ELKNRTRH----------------------------------------LQLRDSLEDLHCTLQEP 451
            ..|.|..|                                        ..|.|....|...:|.|
Zfish   328 TFKGRWEHSILCYSPEYAQGEEILDAVYGFQLCQNFSAPVVLTSTSTEAMLPDITSSLFGNMQTP 392

  Fly   452 KLSHFVDPVPPTILDVLNIGGFTAIGSNS----------ASMGGVGNSVVGSSYSGL--TMDDSR 504
            ....:.:          :.|.||.:.:.:          |:...|..:.|...||.:  |:...|
Zfish   393 TQDFYAE----------DFGSFTIVTTTTTTTQPPRTALATTMTVEGADVTEDYSAMDNTLLTQR 447

  Fly   505 KHLGSR---------------SRQ----ALRGQRQFASSAENVVESKMRRRRKRQEEVKEKDLAA 550
            ..:|:.               ||:    .||..|. .|:.:|      ||:.:.|:.....|||.
Zfish   448 VIIGTMALLFSFFLIIFVVYISRKCCPPTLRRIRH-CSAIQN------RRQMRTQQRQPMADLAT 505

  Fly   551 VAPAHKRYDYYDDNN--GGMSL--GHG 573
            ..|    |:.|:.::  |.:.:  |:|
Zfish   506 QVP----YNEYETSHEEGALVIINGYG 528

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ConNP_001246635.1 LRR_RI <147..291 CDD:238064 26/76 (34%)
LRR_8 183..243 CDD:290566 11/28 (39%)
leucine-rich repeat 185..208 CDD:275380
leucine-rich repeat 209..232 CDD:275380 6/17 (35%)
LRR_RI <225..416 CDD:238064 65/233 (28%)
LRR_8 232..291 CDD:290566 20/58 (34%)
leucine-rich repeat 233..256 CDD:275380 10/22 (45%)
leucine-rich repeat 257..280 CDD:275380 6/22 (27%)
leucine-rich repeat 281..304 CDD:275380 10/22 (45%)
LRR_8 304..363 CDD:290566 18/58 (31%)
leucine-rich repeat 305..328 CDD:275380 6/22 (27%)
leucine-rich repeat 329..352 CDD:275380 7/22 (32%)
LRR_8 352..416 CDD:290566 23/106 (22%)
leucine-rich repeat 353..376 CDD:275380 7/22 (32%)
LRRCT 414..>450 CDD:214507 10/79 (13%)
lrrtm2NP_001338621.1 LRR_8 66..121 CDD:316378 19/52 (37%)
leucine-rich repeat 66..86 CDD:275380 6/17 (35%)
leucine-rich repeat 87..110 CDD:275380 10/22 (45%)
LRR <108..>295 CDD:227223 51/186 (27%)
leucine-rich repeat 111..134 CDD:275380 6/22 (27%)
leucine-rich repeat 135..158 CDD:275380 10/22 (45%)
leucine-rich repeat 159..182 CDD:275380 6/22 (27%)
leucine-rich repeat 183..206 CDD:275380 7/22 (32%)
leucine-rich repeat 207..230 CDD:275380 7/22 (32%)
leucine-rich repeat 231..254 CDD:275380 6/22 (27%)
leucine-rich repeat 255..278 CDD:275380 2/22 (9%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170574196
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.930

Return to query results.
Submit another query.