Protein Alignment Con and lrig1

DIOPT Version :10

• Sequence 1: NP_523930.3
• Gene: Con / 38590
• FlyBaseID: FBgn0005775
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_002938412.1
• Gene: lrig1 / 100491453
• XenbaseID: XB-GENE-494193
• Length: 1043
• Species: Xenopus tropicalis
• Alignment Length: 425
• Identity: 112/425 - (26%)
• Similarity: 178/425 - (41%)
• Gaps: 62/425 - (14%)

  Fly   170 RLDYIPTMIIEPLKNLSSIVIEYSQVEIVKSYAFANLPFLERIILNNNHIMALDQDAFANHIRLR 234
            |:..:|..:.. |..|:.:.:..:::.:::...|..|..||.:.|..|:|..|...||....|::
 Frog   186 RISQLPVKVFR-LPRLTQLELNRNRIRLIEGLTFQGLESLEVLKLQRNNISKLTDGAFWGLSRMQ 249

  Fly   235 ELNLEHNQIFEMDRYAFRNLPLCERLFLNNNNISTLHEGLFADMARLTFLNLAHNQINVLTSEIF 299
            .|:||:|.:.|::..:...|...::|.|::|:|||:....::...:|..|.|:||.:..|.....
 Frog   250 ILHLENNSLTEVNSGSLYGLLSLQQLHLSHNSISTISSAGWSFCQKLQELVLSHNNLTRLDEGSL 314

  Fly   300 RGLGNLNVLKLTRNNLNFIGDTVFAELWSLSELELDDNRIERISE---RALDGLNTLKTLNLRNN 361
            ..||.|:||:|:.|:::.|.:..|..|.||..||||.|.|....|   .|..||.:|..|.|..|
 Frog   315 ADLGVLDVLRLSYNSISHIAEGAFKGLKSLRILELDHNEISGTIEDTNGAFIGLESLNKLTLFGN 379

  Fly   362 LLKKIDNGLLRGTPALLSINVQANKLETLTFYTFQPIMDNLVNSTSELLVSDNKFICDCRLQWIF 426
            .:|.:......|..:|..:|:..|.|.::....|.. |.||    .||:|..:.|:|||.|:|:.
 Frog   380 KIKSVAKRAFSGIESLEHLNLGENALRSVHSEAFGE-MKNL----KELVVGSSSFLCDCHLKWLP 439

  Fly   427 ELKNRTRHLQLRDSLEDLH-------CTLQEPKLSHFVDPVPPTILDVLNIGGFTAIGSNSASMG 484
            :... :|.||.:......|       .....|..|...|.:|...:.|          ....:|.
 Frog   440 QWLT-SRRLQTKVKASCAHPGSLNNTSIFSVPPRSFVCDDLPKPQIRV----------QPETTMA 493

  Fly   485 GVGN------SVVGSSYSGLTM----DDSRKHLGSRSRQALRGQRQFASSAENVVESKMRRRRKR 539
            .:|.      |...||.|.:|.    |:...|...        ...|||..|            |
 Frog   494 VLGKAIRFTCSAASSSPSPMTFAWKKDNEILHNAE--------VENFASGTE------------R 538

  Fly   540 QEEVKE----KDLAAVAPAHK-RYDYYDDNNGGMS 569
            :.||.|    ..|..:..||: ||.....|:.|.|
 Frog   539 EGEVTEYTTILHLRNLTFAHEGRYQCIITNDFGPS 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Con	NP_523930.3	LRR	<157..459	CDD:443914	84/298 (28%)
		leucine-rich repeat	185..208	CDD:275380	3/22 (14%)
		leucine-rich repeat	209..232	CDD:275380	8/22 (36%)
		leucine-rich repeat	233..256	CDD:275380	6/22 (27%)
		leucine-rich repeat	257..280	CDD:275380	6/22 (27%)
		leucine-rich repeat	281..304	CDD:275380	7/22 (32%)
		leucine-rich repeat	305..328	CDD:275380	8/22 (36%)
		leucine-rich repeat	329..352	CDD:275380	11/25 (44%)
		leucine-rich repeat	353..376	CDD:275380	6/22 (27%)
lrig1	XP_002938412.1	LRR	<39..362	CDD:443914	52/176 (30%)
		leucine-rich repeat	57..80	CDD:275378
		leucine-rich repeat	104..127	CDD:275380
		leucine-rich repeat	128..151	CDD:275380
		leucine-rich repeat	152..199	CDD:275380	3/13 (23%)
		leucine-rich repeat	200..223	CDD:275380	3/22 (14%)
		leucine-rich repeat	224..247	CDD:275380	8/22 (36%)
		leucine-rich repeat	248..295	CDD:275380	12/46 (26%)
		leucine-rich repeat	272..292	CDD:275380	6/19 (32%)
		leucine-rich repeat	296..319	CDD:275380	7/22 (32%)
		leucine-rich repeat	320..343	CDD:275380	8/22 (36%)
		LRR_8	343..405	CDD:404697	21/61 (34%)
		leucine-rich repeat	344..370	CDD:275380	11/25 (44%)
		leucine-rich repeat	371..394	CDD:275380	6/22 (27%)
		leucine-rich repeat	395..413	CDD:275380	4/17 (24%)
		LRRCT	429..477	CDD:214507	12/48 (25%)
		leucine-rich repeat	445..471	CDD:275380	4/25 (16%)
		Ig_3	481..568	CDD:464046	23/116 (20%)
		IgI_LRIG1-like	587..677	CDD:409420
		Ig strand A	587..590	CDD:409420
		Ig strand A'	594..598	CDD:409420
		Ig strand B	601..610	CDD:409420
		Ig strand C	616..621	CDD:409420
		Ig strand C'	624..626	CDD:409420
		Ig strand D	634..638	CDD:409420
		Ig strand E	642..649	CDD:409420
		Ig strand F	655..663	CDD:409420
		Ig strand G	666..677	CDD:409420
		I-set	680..759	CDD:400151
		Ig strand C	710..714	CDD:409353
		Ig strand E	733..737	CDD:409353
		Ig strand F	747..752	CDD:409353