DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh50 and Rhbg

DIOPT Version :9

Sequence 1:	NP_001369039.1	Gene:	Rh50 / 38589	FlyBaseID:	FBgn0028699	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_898877.1	Gene:	Rhbg / 310625	RGDID:	727813	Length:	455	Species:	Rattus norvegicus

Alignment Length:	444	Identity:	201/444 - (45%)
Similarity:	284/444 - (63%)	Gaps:	19/444 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VVLMIVQIIF----LVLFWLFVRY-EKTALPLAIDAEDAGSANEHVSKYPQFQDIQVMIFIGFGF 71
            :||.::.::|    .:||.:|||| .:|...|......:...||...:||.|||:.||:|:||||
  Rat    10 LVLPLLCLLFQGATSLLFAIFVRYNHETDAALWHWGNHSNVDNEFYFRYPSFQDVHVMVFVGFGF 74

  Fly    72 LMTFLRKYGYSATGFTLFMAALVVQWAVLMKGFLH-MEGGKISLSLENIIDADIAAAVPLISMGA 135
            ||.||::||:|:.|||..:|...:|||.|::|||| ..||.|.:.:|::|:||..|...|||.||
  Rat    75 LMVFLQRYGFSSVGFTFLVATFTLQWATLLQGFLHSFHGGHIHIGVESLINADFCAGAVLISFGA 139

  Fly   136 LLGRTTPIQLLCMSVFEVALFAANEYLALHVFSICDCGGSITVHAFGAYFGLAVALMLRPASDQN 200
            :||:|.|.|||.|::.|..||:.||::.|.:..:.|.|||:|:|.|||||||.::.:|. .|...
  Rat   140 VLGKTGPAQLLLMALLEAVLFSVNEFILLSLLGVRDAGGSMTIHTFGAYFGLFLSRVLY-RSQLE 203

  Fly   201 ETGKLEGASYTSDIFAMIGTTFLWVYWPSFNSV-LADGAGGERAILNTFLSLAAATVTTFVVSAL 264
            ::...:.:.|.||:||||||.||||:||||||. .|.|.|..|.::||:.||.|:|::||.:|||
  Rat   204 KSRHRQTSVYNSDLFAMIGTIFLWVFWPSFNSAPTALGDGQHRTVVNTYYSLTASTLSTFALSAL 268

  Fly   265 VSHENKLDMVHVQNSTLAGGVAVGTVCNLLLGAHGAVLIGIIAGTVSVLGYRYLTPWMTANLRLH 329
            ||.:.:|||||:||:.|||||.|||...::|...||:..|.:|||||.|||::.||.:.:..:|.
  Rat   269 VSGDGRLDMVHIQNAALAGGVVVGTASEMMLTPFGALAAGFLAGTVSTLGYKFFTPILESRFKLQ 333

  Fly   330 DTCGVHNLHGMPALISAIASAIYASMATVGEYQSELQDIFPAMVGTNGTETKIMGGLGRNATSQA 394
            ||||||||||||.::.||...:.|::||...|...||.:||.:....           |:|||||
  Rat   334 DTCGVHNLHGMPGVLGAILGVVVAALATHEAYGDGLQTVFPLIAKGQ-----------RSATSQA 387

  Fly   395 GYQLFGIAVTLLIAIGGGILTGAVLKYTNFRNLKKDEHHQDEHYWEVPAAENKE 448
            .|||||:.|||:.|..||.|.|.:|:.....:....:..:|:.|||||..:..|
  Rat   388 MYQLFGMFVTLVFASVGGSLGGLLLRLPFLDSPPDSQCFEDQVYWEVPGEQEAE 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh50	NP_001369039.1	Ammonium_transp	55..422	CDD:413553	181/368 (49%)
Rhbg	NP_898877.1	Ammonium_transp	58..403	CDD:275788	176/356 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354044
Domainoid	1	1.000	370	1.000	Domainoid score	I873
eggNOG	1	0.900	-	-		E1_KOG3796
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9469
Inparanoid	1	1.050	383	1.000	Inparanoid score	I1974
OMA	1	1.010	-	-		QHG54631
OrthoDB	1	1.010	-	-		D311058at33208
OrthoFinder	1	1.000	-	-		FOG0000589
OrthoInspector	1	1.000	-	-		otm44576
orthoMCL	1	0.900	-	-		OOG6_101421
Panther	1	1.100	-	-	LDO	PTHR11730
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X200
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770