DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh50 and rhcga

DIOPT Version :9

Sequence 1:	NP_001369039.1	Gene:	Rh50 / 38589	FlyBaseID:	FBgn0028699	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_001083046.1	Gene:	rhcga / 100038797	ZFINID:	ZDB-GENE-070424-81	Length:	489	Species:	Danio rerio

Alignment Length:	497	Identity:	203/497 - (40%)
Similarity:	297/497 - (59%)	Gaps:	53/497 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SPAAKVSGYVVLMIVQIIFLVLFWLFVRYE----------KTALPLAIDAEDAGSANEHVSKYPQ 57
            :|..:||..:|..|.||..::||.|||||:          |....:..|.|     |:...:||.
Zfish    17 NPNVRVSLPIVCFIWQIAMIILFGLFVRYDIESDAHWAEHKKHENITSDIE-----NDFYFRYPS 76

  Fly    58 FQDIQVMIFIGFGFLMTFLRKYGYSATGFTLFMAALVVQWAVLMKGFLHM---EGGKISLSLENI 119
            |||:.||||:|||||||||::|.:.|.||...:||..:|||:||:|:.|.   ..|.|.:.:|::
Zfish    77 FQDVHVMIFVGFGFLMTFLKRYSFGAVGFNFLVAAFGLQWALLMQGWFHSLDPVDGTIKIGVESL 141

  Fly   120 IDADIAAAVPLISMGALLGRTTPIQLLCMSVFEVALFAANEYLALHVFSICDCGGSITVHAFGAY 184
            |:||...|..||:.|||||:.:|:||:.|::|.:.|:|..||:.|::..:.|.|||:.:|.||||
Zfish   142 INADFCVAGCLIAYGALLGKVSPVQLMVMTLFGITLYAVEEYIILNLLHVRDAGGSMVIHTFGAY 206

  Fly   185 FGLAVA-LMLRPASDQNETGKLEGASYTSDIFAMIGTTFLWVYWPSFNSVLAD-GAGGERAILNT 247
            :||.:: ::.||..||.:  .|.|:.|.||:||||||.|||::||||||.::: |.|..||.:||
Zfish   207 YGLTISWILYRPKLDQAK--HLNGSVYHSDVFAMIGTLFLWMFWPSFNSAISNHGDGQHRAAINT 269

  Fly   248 FLSLAAATVTTFVVSALVSHENKLDMVHVQNSTLAGGVAVGTVCNLLLGAHGAVLIGIIAGTVSV 312
            :|||||:.:|||.:|::.:.:.|:||||:||:|||||||:||....::..:|::::|...|.:|.
Zfish   270 YLSLAASVLTTFAISSMSAKKGKVDMVHIQNATLAGGVAMGTAAEFMISPYGSLIVGFCCGIIST 334

  Fly   313 LGYRYLTPWMTANLRLHDTCGVHNLHGMPALISAIASAIYASMATVGEYQSELQDIFPAMVGTNG 377
            .||..:||:|...|::.|||||||||.||.||..|..||.|:.|:            |.:.|..|
Zfish   335 FGYVVITPFMEKYLKIQDTCGVHNLHAMPGLIGGIVGAITAAAAS------------PTVYGQEG 387

  Fly   378 TETKIMGGLG----RNATSQAGYQLFGIAVTLLIAIGGGILTGAVLKYTNFRNLKKDEHHQDEHY 438
            . ..:.|..|    |::.:|.|||..||||.|...|.|||:.|.:|:...:.:...:....||.|
Zfish   388 L-VNLFGFTGDYANRSSATQGGYQAAGIAVALAFGIVGGIIVGCILRLPIWGDPSDENCFDDEVY 451

  Fly   439 WEVPAAENK-----EEYLNMLAKLLDDDAAATNSNSQSAANF 475
            ||||..|..     |...:|:.|         |.:..|.:||
Zfish   452 WEVPEDEESIPPVLEYSSHMVGK---------NPDMMSESNF 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh50	NP_001369039.1	Ammonium_transp	55..422	CDD:413553	170/375 (45%)
rhcga	NP_001083046.1	Ammonium_transp	74..451	CDD:275788	172/391 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596270
Domainoid	1	1.000	362	1.000	Domainoid score	I902
eggNOG	1	0.900	-	-		E1_KOG3796
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	383	1.000	Inparanoid score	I2002
OMA	1	1.010	-	-		QHG54631
OrthoDB	1	1.010	-	-		D311058at33208
OrthoFinder	1	1.000	-	-		FOG0000589
OrthoInspector	1	1.000	-	-		otm24460
orthoMCL	1	0.900	-	-		OOG6_101421
Panther	1	1.100	-	-	O	PTHR11730
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X200
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770