Protein Alignment CG13705 and FSCB

DIOPT Version :10

• Sequence 1: NP_647938.1
• Gene: CG13705 / 38587
• FlyBaseID: FBgn0035582
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_115511.3
• Gene: FSCB / 84075
• HGNCID: 20494
• Length: 825
• Species: Homo sapiens
• Alignment Length: 453
• Identity: 118/453 - (26%)
• Similarity: 174/453 - (38%)
• Gaps: 141/453 - (31%)

  Fly    16 AASIATDYLPPVDNNLESASELVEVPAEQGVLSDDGYRYKTVRRL-KLRHRRDVNELPSGEYLP- 78
            :..:..:.|||  :..||.||  |.|||  :|.....:..:|..| ::|.       ||.:..|
Human   343 SVELLAEILPP--SAEESPSE--EPPAE--ILPPPAEKSPSVELLGEIRS-------PSAQKAPI 394

  Fly    79 -----PVEESASEAVA-VETPLADDGYRYKTVRRVIRRRRDVSELSPEYLPPVEESASE---AVA 134
                 |.|.:..||.| ||.|         ||...:   .||..|.||..|  .|.|.|   :.|
Human   395 EVQPLPAEGALEEAPAKVEPP---------TVEETL---ADVQPLLPEEAP--REEARELQLSTA 445

  Fly   135 VETPLADDGYRYKTVRRVIRRRRDVSELSPEYL------PPVEESASEAVAVETPLADD---GYR 190
            :|||..:....:::   .:.:.....|.|.|..      ||.:|:.:||   .:||:::   ...
Human   446 METPAEEAPTEFQS---PLPKETTAEEASAEIQLLAATEPPADETPAEA---RSPLSEETSAEEA 504

  Fly   191 YKTVRRVIRRRRDVSELSPE--YLPPVEESASEAVA-VDTPLADDGYRYKT---VRRVIRRRRDV 249
            :..|:..:.......|.|.|  .|..:|..|.|..| ..:||:::....:.   |:....:...:
Human   505 HAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSI 569

  Fly   250 NELPSGEYLPP--VEESASEAVAVETPLAADGYRYKTVRRVIRRRRDVNELSAEYL------PPV 306
            .|.|. |..||  .|.:|.||.|....|||                  .|.|||..      ||.
Human   570 EEAPL-ELQPPSGEETTAEEASAAIQLLAA------------------TEASAEEAPAEVQPPPA 615

  Fly   307 EES--------ASEAVA-VETPLADDGYRYKTVRRVIRRRRDVSELSPEYLPPVEES-------- 354
            ||:        |.||.| |:.|.|::.               .:|:.|   ||.||:
Human   616 EEAPAEVQPPPAEEAPAEVQPPPAEEA---------------PAEVQP---PPAEEAPAEVQPPP 662

  Fly   355 ASEAVA-VETPLADDGYRYKTVRRVIRRRRDVSELPSGEYLPPVEETASAI-----IDVPAEQ 411
            |.||.| |:.|.|::.            ..:|..||:.|  .|:|||.:|:     .|||||:
Human   663 AEEAPAEVQPPPAEEA------------PAEVQSLPAEE--TPIEETLAAVHSPPADDVPAEE 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13705	NP_647938.1	GYR	49..66	CDD:426962	3/17 (18%)
		GYR	417..432	CDD:426962
FSCB	NP_115511.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	113..139
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	168..232
		rne	<231..379	CDD:236766	12/41 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	244..718		118/453 (26%)
		PRK12323	<277..484	CDD:481241	45/170 (26%)
		2A1904	<443..>588	CDD:273344	33/151 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	732..751