DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13705 and CG32237

DIOPT Version :9

Sequence 1:	NP_647938.1	Gene:	CG13705 / 38587	FlyBaseID:	FBgn0035582	Length:	432	Species:	Drosophila melanogaster
Sequence 2:	NP_729037.1	Gene:	CG32237 / 38584	FlyBaseID:	FBgn0052237	Length:	911	Species:	Drosophila melanogaster

Alignment Length:	529	Identity:	258/529 - (48%)
Similarity:	329/529 - (62%)	Gaps:	108/529 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFFVIAFAVIAAASAA--------------SIATDYLPPVDNNLESASELVEVPAEQGVLSDDG 51
            ||.| :|...||||:||              .|..:|:||.:   |..:||.:.||   .|.|||
  Fly     1 MKLF-LACIFIAAATAAVIPVEQARHRRDVSEIVNEYIPPAE---EVGAELAQDPA---ALGDDG 58

  Fly    52 YRYKTVRRLKLRHRRDVNELPSGEYLPPVEESASEAVAVETP----------LADDGYRYKTVRR 106
            ||||||||||||.||||:|: :.|||||.||..::|...|.|          ||.|||:||||||
  Fly    59 YRYKTVRRLKLRQRRDVSEI-ANEYLPPTEEVVADAPVEEVPVEEASQDSAVLAADGYQYKTVRR 122

  Fly   107 V-IRRRRDVSELSPEYLPPVEESASEAVAVETP----------LADDGYRYKTVRRV-IRRRRDV 159
            : .|:|||||:::.|||||.||..::|...|.|          ||.|||:||||||: .|:||||
  Fly   123 LKYRQRRDVSDIANEYLPPTEEVVADAPVEEVPVEEASQDSAVLAADGYKYKTVRRLKYRQRRDV 187

  Fly   160 SELSPEYLPPVEESASEAVAVETP----------LADDGYRYKTVRRV-IRRRRDVSELSPEYLP 213
            ||::.|||||.||..::....|.|          ||.|||:||||||: .|:||||||::.||||
  Fly   188 SEIANEYLPPTEEVVADTPVEEVPVEEASQDSAVLAADGYKYKTVRRLKYRQRRDVSEIANEYLP 252

  Fly   214 PVEESASEAVAVDTP----------LADDGYRYKTVRRV-IRRRRDVNELPSGEYLPPVEESASE 267
            |.|::|:||...:.|          ||.|||:||||||: .|:||||:|: :.|||||.||..::
  Fly   253 PTEDAATEAPIEEAPVEEASQDSAVLAADGYQYKTVRRLKYRQRRDVSEI-ANEYLPPTEEVVAD 316

  Fly   268 AVAVETP----------LAADGYRYKTVRRV-IRRRRDVNELSAEYLPPVEESASEAVAVETP-- 319
            |...|.|          ||||||:||||||: .|:||||:|::.|||||.||..::|...|.|
  Fly   317 APVEEVPVEEASQDSAVLAADGYKYKTVRRLKYRQRRDVSEIANEYLPPTEEVVADAPVEEVPVE 381

  Fly   320 --------LADDGYRYKTVRRV-IRRRRDVSELSPEYLPPVEESASEAVAVETP----------L 365
                    ||.|||:||||||: .|:||||||::.|||||.||..::|...|.|          |
  Fly   382 EASQDSAVLAADGYQYKTVRRLKYRQRRDVSEIANEYLPPTEEVVADAPVEEVPVEEASQDSAVL 446

  Fly   366 ADDGYRYKTVRRV-IRRRRDVSELPSGEYLPPVEETA--SAIIDVPAEQ-----TVLASDGYRYK 422
            |.|||:||||||: .|:||||||: :.|||||.||..  :.:.:||.|:     .|||:|||:||
  Fly   447 AADGYKYKTVRRLKYRQRRDVSEI-ANEYLPPTEEVVADAPVEEVPVEEASQDSAVLAADGYQYK 510

  Fly   423 TVRRLKLRR 431
            ||||||.|:
  Fly   511 TVRRLKYRQ 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13705	NP_647938.1	GYR	49..66	CDD:128953	15/16 (94%)
CG13705	NP_647938.1	GYR	417..432	CDD:128953	12/15 (80%)
CG32237	NP_729037.1	GYR	56..73	CDD:128953	15/16 (94%)
		GYR	168..185	CDD:128953	10/16 (63%)
		GYR	224..241	CDD:128953	10/16 (63%)
		GYR	336..353	CDD:128953	11/16 (69%)
		GYR	448..465	CDD:128953	10/16 (63%)
		GYR	616..633	CDD:128953
		GYR	728..745	CDD:128953
		GYR	892..909	CDD:128953
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450153
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2CKD8
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008548
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR36135
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840