DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dnah3 and Dnhd1

DIOPT Version :9

Sequence 1:	NP_647937.2	Gene:	Dnah3 / 38586	FlyBaseID:	FBgn0035581	Length:	4385	Species:	Drosophila melanogaster
Sequence 2:	NP_001357732.1	Gene:	Dnhd1 / 77505	MGIID:	1924755	Length:	4749	Species:	Mus musculus

Alignment Length:	5012	Identity:	968/5012 - (19%)
Similarity:	1727/5012 - (34%)	Gaps:	1397/5012 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   338 PYMQPLQPVDPDDQKIKMLAKYRVELARAEKLFTLKIQKRY---QCLLKSMSIVQLATYPSHLIR 399
            |:::.|....|     |:.|:..::|..|       |.|.:   ..||.|.|.|...     |..
Mouse   151 PFLEQLYCWAP-----KVQARLELDLLDA-------IDKAFPPDSSLLHSSSHVDCG-----LWM 198

  Fly   400 KAFRRINPRSALLQDAYQFIVKEKRD---W--PKLPPEV-----ILMDYLFVGDRGVRQDLAILI 454
            |.|.|..|.||......|:..::|::   |  |...||:     |:...:.:.:......|::|.
Mouse   199 KRFHRGPPCSACPFVKAQWDRQQKKELATWLRPLTLPELQHCLGIVGAEVALEETPWLDSLSLLP 263

  Fly   455 IVCLIDLQEDFRHYVKRSFLNYLLSSNMER-------RRLQLEREPPEFPILTISPPVSWRSNLL 512
            :....|:...:.            ||:.|:       |:||:..|.||...|   ...|.|:.:|
Mouse   264 LALATDIPVQYE------------SSDTEQAEGEPAGRKLQVASEAPEEKAL---KKKSSRTPVL 313

  Fly   513 RGKARIGEVLMTTHPTVQALNRLW-----HDLYEDLVVVD--LGQLLLAQRPLDADTVQVFI--- 567
            |.:.:            ..|.|.|     |.||.: ||.|  .....|...|.|....:.:|
Mouse   314 RSQVK------------SLLERDWTQKKIHFLYLN-VVSDRHFNPYKLVAVPPDKVNPEHYIFSP 365

  Fly   568 --------------------EKSCADVRDLLLNDWLPRCADLMNEMRGTWKDLVPMSGKYGGRAA 612
                                .:.||..|:|....:...|  |:.:....||..|.:.|.:   ..
Mouse   366 FGILHIHPVEGSEAMTLGTWHRDCALWRELQRIPFFKNC--LLRKALTCWKKNVRLCGLH---RI 425

  Fly   613 MLFRCIH--SAMSR------HLNSLIS--KSINYL------------------------FKVLCA 643
            ..|...|  ||:..      |:|.|:.  :|:::|                        .:|||.
Mouse   426 QTFLKTHLLSAIPHFGAGMLHINRLLQEFRSVSWLPKEPDRSYELVDLQKAIAKENHKALRVLCH 490

  Fly   644 F--------------------------KGGNRIEK-----YSM------FDAKLKRIPLMTLIAS 671
            |                          :..|||.|     |..      .:.|||:.....|...
Mouse   491 FLNLCTSILQLIHEDTYQMQQGLQERVQNWNRIRKGQGSIYLQRTLCRHLEKKLKQAETWLLKLG 555

  Fly   672 VVGAHFDHEPINMGPGVRPASNIYVYDEDD-----ADPFQQPQVNQFVENVPDIDDVAQFELDHS 731
            ......|:         ....|:....||:     |:..|.|:.|.|:.:....||..|......
Mouse   556 KFARLIDY---------MICQNLVSILEDEISSFIANTLQAPRQNPFLLSQLVFDDNGQLSPMPR 611

  Fly   732 NKLYIYPYMQELPRIFTEHFKSILAVGYEIPR--------------LEFVMSGGEPETKG----- 777
            .:..|...::.|..|.|...|.:.:......|              .||:|    |:..|
Mouse   612 VESIIQGLIKSLQSIKTSALKVLQSTDLRTSRDLLYSEDNKDQDSNAEFLM----PKFHGKASDA 672

  Fly   778 ----------------------------------FLHFIDEDHV-DFLELCEKVEQIVKVNW--- 804
                                              ||| .:.||| :.|:....::|.:.|..
Mouse   673 VRLFCGPNVGYVWPWKSHAITDVLEVRGHKLRGQFLH-PNYDHVQEDLDKNAGIQQALAVQQSLL 736

  Fly   805 ----QGVHVYLKPVYKYYFGLFQKLILPMVQKVWTENNLPEL---------GAVQELLKKLQAVS 856
                |.|..:... :|:..|:::.|      |.|:...|.:|         ..|.:|.|..:.||
Mouse   737 EDMRQEVQEFCNK-HKWVEGIYEFL------KAWSSQKLEDLRGSPINNYVNLVIQLKKWQERVS 794

  Fly   857 DTTYYLRDFIPLNLFMLDNRHVKLSLRMYVREIYDFIIDFYKALNWNENRAICEELEEM------ 915
            :.:..|  .....|..|....|:..|...:..:...|::..:...|:.|:.:..||.|.
Mouse   795 NMSVEL--LTKGKLLFLSGHDVQEELGSKLNNMRKNILEQAQNECWSRNQQLMTELTEFLRVFQT 857

  Fly   916 -----------SMKAGERPEETPEVVALQNYINDCREM-----RIFAIKDEIKNVLKR---VVFL 961
                       |.|..|..|:..::.....|:....::     .:|..::|..::...   ..|.
Mouse   858 ISSDIHAIAQCSQKLSEANEQYCQLEERVEYVRSLHDLIRNHCALFIAENETLDIALLDLWEAFQ 922

  Fly   962 LTHTYLSSDELHLNSRTFILPGELEEVLDLSAARLAVVRDNLELALRERRMEFEKLLAQEKRTMD 1026
            ...:.:|  |..|:.:..|:|    .:..|.||.||.:...|..||....|:    .:||:|:.:
Mouse   923 FERSQVS--EFLLSKQHAIVP----RLQQLMAAALAELEGLLAKALSGPFMD----PSQEQRSTE 977

  Fly  1027 GFRIREIRDVLTLEELKERVDTVDLLFTTIENLSREAKAINTEETLLQIDVSAFPLLAEIIEKME 1091
                             :::..::..|..|         :|....|    .:|:.......:.|.
Mouse   978 -----------------QQLGALEHQFLNI---------LNNFNAL----CNAYCTFTGYKKPMS 1012

  Fly  1092 P----------IEKLWKTSYEFEKDYLIWMFERFECLNADGVREQVENMHKIMYKLSRQLA-YNP 1145
            |          .:::|:......::...|....|...|....||:.:.......:||..|. .:|
Mouse  1013 PPASGNRPIVLQQRIWRLYRIISENLGEWKCVAFSKFNLSMAREKTDAWLTEAVRLSTALGLQSP 1077

  Fly  1146 VAKRAAEQMRMKIEKFRVYLPVLDSICRHGLEKRHWDQISKILG----RKVNPKLFPTLKDMIDV 1206
            |.:|.   ||| :|:||.|||:|..:....|:..:...:.:.||    |.::   ..||..|::.
Mouse  1078 VLQRC---MRM-LEEFRAYLPLLIKLGNLQLQDLNTQSLLRALGLGSLRSLD---LLTLGQMLNY 1135

  Fly  1207 DIMSILPQLEEIANAAGKEYDLNNGLRIMQADWRDVMFEVLQY---------------------- 1249
            .::....::.::.....:.......|:.||..|......:|.:
Mouse  1136 PLLEFAERINQVWQYDKERIHAQEILQQMQQYWEGRQLRLLNFILHVPYKPPTSERSKRPALRSP 1200

  Fly  1250 ------RDSDTHILASLDDIQTLLDDH---IMRTQAMKRSPFITALGSKADDWEARLLLIQNIID 1305
                  :||.|.:|:....:|..:.:.   :.:..|:::|   ..|...|.:|.|.:..:..:::
Mouse  1201 QWELVGKDSGTFLLSDYSSLQDAIQNSLQALFKILAIQKS---GQLHKIALEWVAIMYGLGALLE 1262

  Fly  1306 AWTQVQITWMYLEPIFSSEDIMRQMPLEGRNFKAVDKLWRKIMKHTLKDRHVMAAT--------- 1361
            .|...|..|::|..:.....|....|.....|||:|..:|.:|:.::.|..|::..
Mouse  1263 VWVAFQQKWIFLNKVLHEMKIEFPAPELNARFKAMDDQYRTLMRISVADPMVLSLILPNTKRSPY 1327

  Fly  1362 -EYPEMLEVFTKAIEDLETVTKGLNTYLEQKRLFFARFFFLSNDELLEILSETKDPMRVQPHLRK 1425
             :...:.::......:||.:...|...|......|.|.||||:.||:.:|:...|....|...::
Mouse  1328 FQGQHLQQMLKAGSGELEAIIMALEDVLYGVCANFPRLFFLSDSELVALLAAPLDTREAQLWAQR 1392

  Fly  1426 CFEGIGSLTF----------------DDNMEIVEMVSDEEERVALVRKINPQLANGLVEMWLKEV 1474
            ||..|.::.|                .::.|.:.:::...|.|.|.   .|...:..:..||..:
Mouse  1393 CFPHIKAVNFRSKSTKKKINQDSSSSTESAETIAVLAAGGEEVKLQ---EPLPLHTDLPKWLASL 1454

  Fly  1475 EMVM-------------------------LDSVKEQMREAWEDYAMVERISW---VVSWPGQVVQ 1511
            |..:                         |.::.:|.:...:.|..    .|   |..:|.|.:.
Mouse  1455 EKCLRFIIVNLLQSCVATRLAQGPSLIKALKAMPQQRQMPMQVYVQ----HWLDAVQVFPWQCIL 1515

  Fly  1512 GISCMAWTYEVEEA-IETKEL-PAYLEKSNLQIADLVQLVRTDLQA-------GVR--IAVEALI 1565
            ....:.|..|:||| :|::.: ...:...||::  |||.:|:...:       .||  .....|:
Mouse  1516 VAEEVVWRAEMEEALLESRTMHMRSVHVHNLEV--LVQFIRSQRSSQDGKSLPSVRQTSLFSTLL 1578

  Fly  1566 VLDVHDRDVVKYLTDCRITNIQDFDWISQLRYYWKVNEKN--EDWVCVSMVVT------------ 1616
            |..|..||:.:.|...:::::.||.|:.||:|:...:..|  ....|::.:.:
Mouse  1579 VKAVTHRDIAQLLEKNQVSDLTDFHWVRQLKYHLGSSHLNLKSPVQCLTTIASTEPSVSPAACWI 1643

  Fly  1617 DV-----EYGMEYLGNLPRLVVTP--LTDRCYRTLMGALKLCLGGAPEGPAGTGKTETCKDLAKA 1674
            ||     .|..||:|  |:|...|  :.:|....|:.||.....||..|..|.||.||...||..
Mouse  1644 DVLGRSFMYNYEYMG--PKLGPLPSLMHERQVFILLMALDEVAYGAILGRDGLGKAETVNSLAWT 1706

  Fly  1675 VAKKCVVFNCSDGLDYKALGKFFKGLAQSGAWACFDEFNRIELEVLSVVAQQ------------- 1726
            :.::.|:..|...::::.|..:..|..|||||...:..|::...:||.:.|:
Mouse  1707 LGRQLVIMPCLPQIEFQCLRNYLNGALQSGAWLLLENVNQLPSSLLSALGQRLDELHYLYAPLYQ 1771

  Fly  1727 -----ILTIQRAIGRKVVKFFFEDTMLKLDPTCSIFITMNPGYAGRTELPDNLKVLFRTVAMMVP 1786
                 |.||.......:...|||...:.:......|:|:   ::...::|.||.:|.|.||:.:|
Mouse  1772 KASKNISTINPTKPLLLGGGFFEKHQVSMRLGFGCFLTL---HSLGPDIPANLHLLLRPVALALP 1833

  Fly  1787 DYAMIGEITLYSNGFDMARNLSQKIVQAYKL----------C------------------SEQLS 1823
            |...:.|:.|...|...|..::.::.:.:.|          |                  |::..
Mouse  1834 DLQRVAELNLLGAGVQDASQMASRLSKLFSLERELVSGNLPCRLPLLKQVLEHTIQTLNTSQEKK 1898

  Fly  1824 SQSHYDYGMRAVKSVLLASASLRRLYVDLPEPEIVLRAIVD-VNLPKFLEQDISLFIGIYMDLFP 1887
            ||..||       ......|:|.|..:..|     |.:|:| :.|.|..|    |..||:.:...
Mouse  1899 SQQPYD-------PAASEEAALLRALLHSP-----LFSILDGLRLQKLQE----LLCGIFPNASH 1947

  Fly  1888 GVELPMPQRGDILKWLHI-NLADRNLQATPWYLEKILQIYEMLLVRHGLMIVGGSMGGKTTAYQV 1951
            .:..|:..|  ::|.:.: .|....|......:..:.|:.:.|....|::::|.:..||:|.::.
Mouse  1948 VLAEPVSHR--LIKSVVVEELQQLGLFPASNTVTSLEQLSQALSRASGILLLGPAGSGKSTCWRS 2010

  Fly  1952 LAQTLRNVSTDEEATLKEFPVTFRIIN--PKAITMGQLYGRFDPVSHEWYDGVLAKTF------- 2007
            |.:....::..|..:.|.|. :..|::  |..:...:..|..:..|  |:.|:..|..
Mouse  2011 LFKIQNRLAAMEHTSTKGFQ-SVEIVHLYPSVLNSKEYLGWSEGPS--WHYGIFPKLLHAAPYCK 2072

  Fly  2008 ----REQVQGPKGERAWVMFDGPVDAVWIENLNTVLDDNKKLCLMSGEIMQMTKLMNMMF--EPA 2066
                .|..:...|.:.|::.||..:..|.:::..:|.|..:|.|.:|:  |:.:.:...|  |.|
Mouse  2073 SVGSEEPSEKFTGIQQWIICDGAPNHAWTDSVTCLLRDPPQLSLPNGQ--QIARPLGTFFLIEVA 2135

  Fly  2067 DLEQASPATVSRCGMIYMEPSQLGWRALHKSFINVLVNKVGLGDIYMTLFEDMTEWLVPAALEFL 2131
            :....||..:.||.:::....|. |.::....:..|.::..|....:|.|..:.|.|||:.|.||
Mouse  2136 EAAGMSPTVLGRCALVWCSGEQT-WHSMLSVLMASLPHEYHLQQETITEFNYLAEVLVPSVLRFL 2199

  Fly  2132 PQ---------------CKQMLELSPIYQ-YQTFSRFFLHFLEKHKQFNQAWFQ----------- 2169
            .:               |..:.|::.:.: .:......||..|:.|.:.:..|.
Mouse  2200 TRIGASSQLQVHGHQAVCPGVAEVTSLVRILRALLDPLLHLFEEEKSYTKEDFSGSDLVTQNFKS 2264

  Fly  2170 -----------------------QMFLFCFAWAYCSALTGQGQKTFDALLRKVIYGSNENFPKPK 2211
                                   ..|||...|::.:.|..:....||..::|.| .|..|:|:|.
Mouse  2265 SKTRVQSDRVNVNKKQRRHLLAISSFLFAIIWSFGAHLPSRHWPLFDDFMKKSI-SSLPNYPEPP 2328

  Fly  2212 YFSLNRGQMFPEKLLF-LDYRFDEAENWWTWQKSDDSASTTSNFPENAQISELIV--------PT 2267
                      |..|:| |...|::.                :..|...|.....|        |:
Mouse  2329 ----------PSALVFDLHVNFEDG----------------TLVPFTGQYLSTHVKGNLGSFQPS 2367

  Fly  2268 KETGYISYWQEFCISKSYAMLVVGPTGTGKSAIITSNLLAMPKFANLVNVIN------------- 2319
            .:|..:.|..:..:|....:|:.|...|||||.:  .:|..|.:..:.:.|:
Mouse  2368 SQTEQLLYVVDLLLSNGQPVLLAGEIATGKSAFV--EVLVKPNYPVIHSPIHPALNSTHLRHLLS 2430

  Fly  2320 --FSARTSAQMV----QD---TIMSKLDRRRKGVFGPSLGKKCTVFCDDVAMPSKDTYGSQAPLE 2375
              ...:|.|..:    ||   :|:..::......|.|.  |.|                 |..||
Mouse  2431 RGVHGQTQASSIPGHHQDSKGSILFLMEDLHLATFDPE--KNC-----------------QPVLE 2476

  Fly  2376 LLRTWLDHGYWSDLVDTTKIELVDMTL-MCAMGTLGG--SNFIFPRLYRHMFVVAVDSF-EDSTI 2436
            .||..::...::.  :|.:::.:..|: ..|..|:.|  ...:.|||||...|:|::|. :|:.:
Mouse  2477 TLRQAMEGTIYAH--NTLELQTLQTTVNFLATATVPGYSERPLCPRLYRLFTVLALNSMTQDTLL 2539

  Fly  2437 VRIFTTIGDWHFSKGYP--EKVALLSRGLSEAMVSVYRDAIRSFLPTPAKSHYSFSLRDITRVFQ 2499
            .|...:|..|  .:.:|  |:...|:|.|..|.|..:....:.|:|:|.:.||.||...::.:..
Mouse  2540 SRHVPSIQAW--LERFPSVEREHTLARALVRASVEAWEAVCKCFMPSPLRPHYRFSPHSVSHILG 2602

  Fly  2500 GIVMVPPKR----------------------------MPDPEKLGRLWAHETYRVFYDRLVDQQD 2536
            .:.::|.:.                            |.....:.|||.||..|.|.|||...::
Mouse  2603 SLQLLPTRMGSRGFAETFHHQEYLRRVSGLRGTRLTIMMSMRVMVRLWLHEAQRTFCDRLDSDRE 2667

  Fly  2537 RD---RLLV---------------MAVDACKSNL---RFP-----------------------LE 2557
            |.   :||:               :|.|..:..:   :.|                       .|
Mouse  2668 RSHCAKLLLEVAQNVFCGGPGSESLAKDCEEEEVEEEKVPEVESEEEIAQWETLSNSDSGSEEEE 2732

  Fly  2558 QAFGERIEPGEKLTDN--------------------------DLRN------------------- 2577
            ..:|.:...|..|::|                          |:|:
Mouse  2733 DPYGLQATTGSFLSENSLAPFPRKSVNKENTENVSQMAEQEEDIRDSSSKLQSKTPKHEWQMAPQ 2797

  Fly  2578 ------------LFYGNYMEPD-------------AEPKFYDEGDTYEKLEKLM---KYYLREYN 2614
                        |||......|             ..|..|.|.. :|.|||.:   ...|:..:
Mouse  2798 MDLSLPLLLPVLLFYPQESPSDLVFSLELTLGSNFESPNLYLERQ-WENLEKQLVATAVRLKMNS 2861

  Fly  2615 SFSSTPMDLVMFRFAIEHVSRVSRVLQMPRGNILMVG-MGGSGRRSSARLAAYIADCRLMTVQVS 2678
            .||..|:       .::||:.:.|||..|:.:.|::. ..|:||.::..||:.|....|
Mouse  2862 GFSQCPV-------MVQHVAHLVRVLARPQQHALLLSEFRGTGRYTAIILASSICQAHL------ 2913

  Fly  2679 KSYTITDWRDDLKKILMSASFN---LNHTVFLFSDAQATDEGYVEDIN--------GILNTGDLP 2732
             .|...:..:.:.:.|..||::   ||..|.|.         ..|.:|        .:..:|..|
Mouse  2914 -HYLSVESEEAIFQCLRDASWHAGLLNQPVALL---------VPEGVNVAIFCRLLALATSGSFP 2968

  Fly  2733 NLYQLEDKATIMENM--ANVAKQLGKILDTLPSEVYAYYIDRIREQLHIALAFSPIGDSFKERIR 2795
            :.|...|...|.|:.  .|:|.:.....||:.:..|    .::...||:   |..:||: :.:.:
Mouse  2969 DQYTEADLDNIEEHFPKENIANKHAIKRDTILNRFY----QQVCNNLHM---FFMVGDN-QAQNQ 3025

  Fly  2796 VYPSL------INCCTIDWYMPWPEEALSRVGVYFVSSMNLNRPHGEETQEPVQSKDAADPDEEE 2854
            :.|:|      :...:::.|.||.:.:|.|:..:.:.:         :...|:.......||.:.
Mouse  3026 LAPTLFLNLLQLTIASVERYEPWDQASLVRIAQFCLEN---------DHSLPLDDGSLKYPDFKH 3081

  Fly  2855 VRRETVGVEREQTQLEADLVDCVMYFHQSVVDASEKCYLELNRRNYVTPSAYLELLKAFRTFYTR 2919
            :......:                   .:.:..|..||     ..::.|:..|...|.|:.|...
Mouse  3082 LIPNVANI-------------------MARIHVSSACY-----HKHMCPALPLVTPKTFQDFLDM 3122

  Fly  2920 KLDE----ITRLR---DRYTTGLEKLDFAAGQVGEMQTNLYDLQPKLKVLSEETDRIMVNIERET 2977
            .|.:    :.::|   .|..|.|:.|.....:.....:.|.||:.:||...:........:|:..
Mouse  3123 FLQQQQQMVLQMRMRASRIQTALKTLRLMVERHSTQTSLLTDLEAQLKGSYKSVGICQGQLEQSK 3187

  Fly  2978 AEAEKKKEVVGADEAAANEAAAAAQAIKDDCETDLAEAIPAMEAALEALNTLKPADIFIVKSMKN 3042
            ....:|.......|:..........|:|...|..|.:   ..:|.:..|:.|:.||...::|.:.
Mouse  3188 IMYRQKMIECQHQESLIENLVRQHDALKAQQEVFLEQ---MGKAFVGPLSQLRVADFEEIRSYRA 3249

  Fly  3043 PPYGVKLTMEAVCVIRGIKPDRKPDPSGHMVEDYWGPSMRMLSDMKFLDSLKTFDKDNIPPPIIK 3107
            ||..|....:|:|.:            .|. |..|..:.::|....|...|..|.|:.:....:.
Mouse  3250 PPESVVKVTDALCDL------------FHQ-ETGWSSAKQLLCTEDFYQELVFFPKEKLTDSELV 3301

  Fly  3108 RIREKY----IADRDFVPEKIKAASMACEGICRWVRAMDVYDKVARIVMPKKAALAEAEGELSQQ 3168
            ::.|..    ::|.......|.||::|.     |:.|:..|....|..:|....|.:.:..|:::
Mouse  3302 KLNEALRAPGMSDAALRSVSIPAANLAV-----WLWAVLRYGLAQRRGLPTGLLLRQVDATLARE 3361

  Fly  3169 MEKLNAKRAELQVILDKLQKLNDFFAEKSREKKRLED---EIDNCEKKLNRAE-------KLLGG 3223
            ..:|...:.:...:|::.:.|.          |:|||   ..::..:.||:|:       .:...
Mouse  3362 QARLGQFQFQAHDLLEQTRSLT----------KKLEDAQVSHNHVMETLNQAQCGNFQKWPMESA 3416

  Fly  3224 LGGEKTRWSEAAKNLHESISNIVGDVLLAGGCTAYLGYFTTEYRVNILDDWNALC---------- 3278
            |......|:...:.|.|....:.||.||......|||.|..:.|..:|:.|.:||
Mouse  3417 LLTPMHMWTTQLQKLQEQAKTVFGDALLCSAAIIYLGPFPPQRRQELLEKWLSLCQGSEEALDPD 3481

  Fly  3279 --------------KRKHIPSSETFSLATTLGHPMTIRAWSLAGLPADNFSVENGIIVT-----N 3324
                          |...:|:...||:.|.|.:...:..|.....|....:...|:::.     :
Mouse  3482 DVARALRQKSVGVPKNPLLPTRTPFSILTLLSYGSELHQWDRDLKPQAKSARLLGLLLRSHIHFS 3546

  Fly  3325 SSRYSLLIDPQVQANKWIK----------------------------------NMEKNNN----- 3350
            |||:.|||||..||..|:.                                  .:|..||
Mouse  3547 SSRWPLLIDPSNQAIMWLNPLPPKQNRSLEPSPKESKEKFHVTKQDSGDNTEDELEDENNEEEDE 3611

  Fly  3351 ---------------------------------------------------LKVIKQSDANY-MQ 3363
                                                               |.|:..:|... .|
Mouse  3612 ANEQRKEQKAEENKIQGENEQEVQETEKENEPESSGSHSSLPSETQSLPSCLTVLSGTDPELGPQ 3676

  Fly  3364 VLELAITFGQPVLIENVGEKL----------DSNLTPILEKNVIKHKGGLFIKSGDQMIEYNPNF 3418
            :||.|.. |.|||:.||...|          ..||:|                     ....|.|
Mouse  3677 LLEAAAN-GLPVLLTNVELSLGCQELQWLLSKKNLSP---------------------PSVQPGF 3719

  Fly  3419 RLYITTCLRNPRYPP---------EVMVMVTVLNFMITEQGLREQLLAIVVAHERPDLQEKKEQL 3474
            .|:::|     .:|.         |::..:.||:..:..:.|.||:|..::..|||:|:.:.:.|
Mouse  3720 CLFLST-----TFPIHALSRVLGFEMLKGLNVLDLGLNMEILEEQMLHEILCRERPELETRWQDL 3779

  Fly  3475 IIESARNRDALYTIESKILEVLSTSEGNVLEDENAIN--ILSSSKILS-----EDIQEKQVIAVA 3532
            .|.:|...:|:...|.::|..|........:....:.  :.:.:||..     |::::::.
Mouse  3780 KIRAADTYEAMKADEEQLLVTLLRQNQKRQKPSKFLRKMVRTQAKICQLNAQMEELEDQKQ---- 3840

  Fly  3533 TEIEIDAARQQYIPVSKHSAILFFCISELANVDPMY-QYSLSWFLNLFVNTILKAPKS------D 3590
               |:.|....|.||:.|...:...:|.|.|:.|.: ..|.:|.  ..:...:.:.||      :
Mouse  3841 ---EVVALWAPYRPVAYHGMAMVEALSPLQNLLPSFCMTSENWL--AVIRRAIDSMKSYDSYRGE 3900

  Fly  3591 QLSERLKNLNDYFTKSIYTN--VCRSLFEKDKL-VISLVMCLGILVSQGRVEKAALLFFLTG--G 3650
            .|...|..|..:..:.:.||  |...|.:...: ....:..|.:.....::|:.||...|:.  .
Mouse  3901 DLPSHLLRLKIHLARQLLTNTVVALGLIQTPLVGAFGALAMLQVTTKTPKLERLALWPGLSASPS 3965

  Fly  3651 IGYK-TIPPNPLGAWLPDKSWASVCKAAD-LEGLKNLPQMMETYSDEWHNFYDASNPDQLQLPAP 3713
            .|:. .||.....|||..|:|.. |.|.: |.....|.:.:..:|..|.::...|:......|.|
Mouse  3966 SGHNMQIPGVIRPAWLSSKAWEE-CGALELLPPFAGLCESLAGHSGVWQDYLSLSSTVLGPAPGP 4029

  Fly  3714 HNTVNDMY-FLIVIKSLRPDKLVPAVRAFIT----RNLDRSFVEPPPFDLAASFADSSPKIPLVF 3773
            ::....:: .||:.:.||||.|..|:....|    |.||.:...|     ...|....|..|::.
Mouse  4030 NSEPLSLFQKLILWRVLRPDCLAGALADLTTSLLGRPLDENLGAP-----TMIFEHIQPTQPILI 4089

  Fly  3774 LLSAGSDPMASLFMFAKQRNM---YDK---LKTISLGQGQGPRAEKMI---MEAARHGQWVVLQN 3829
            ||.....|.|:|......|.:   ::|   |..|:||.........::   .:|...|.|:||.|
Mouse  4090 LLPPPGHPTATLHPVTVIRKLAANHEKPQHLHVIALGSEDWDPVSTVVNTLCQAMLQGHWLVLDN 4154

  Fly  3830 CHVAISW----------MGDLERICNDTTL--------TDGANHDYRLW--CTSYPSAVFPVSVL 3874
            ||:...|          :.|..|:.:|:.|        ....:.|:|||  ..:..|...|..:.
Mouse  4155 CHLMPFWPRELLQPLQGLLDRARVVSDSELLAEPESRSVVTVHRDFRLWLIVPTEASTSLPGMLT 4219

  Fly  3875 QNSVKMTNEPPKGLRANMHRSFTSDPLMRDKFFTNAFLFSDSANKCWLRGVFALVFFHAVVQERR 3939
            |:|:.:.          .::|.....::.|...:...|.:..     |.....|.|.|.::..|:
Mouse  4220 QSSMPVF----------WNQSLELGRILIDSLDSQQGLCTQP-----LTQTLPLFFLHGLLLHRQ 4269

  Fly  3940 EFGPLGWNIPYEFNESDLKIS-------------LLQLKMFINQSQSIPFRGHVYLTGECNYGGR 3991
            .:|              ||:.             .||::..:..|...|....:.||....|||.
Mouse  4270 LYG--------------LKLQAHRGRWSQVTLTRALQIQEQLWASLGNPSAALLELTASVLYGGS 4320

  Fly  3992 VTDDKDRRLILSLLNMIYNPNTIEEDNYALSQSGTYRVPLSP------TRLNSIEYVSSFPLSPH 4050
            :.|.:||..::||.....||..:..|.....|.....:..||      .|.:....:...|..|.
Mouse  4321 LGDLEDREALVSLTRTCLNPRNMNWDQPHTPQYLLATLMPSPELGELDARTDCKAQMHLLPTPPE 4385

  Fly  4051 PEVYGLHENADINRNVKETNALISGVLLTQTDLMASVKASSS------GGAKEDPAIAICKQVLK 4109
            |...||:|........:::..|::          |..|.||:      ||        |.::..:
Mouse  4386 PRTCGLNEAPQAWLMRRQSRVLLN----------ALQKCSSTWVPTVCGG--------IAQRKER 4432

  Fly  4110 QLPEEFNIDEVSKTYPVIYTNSMNTVLRQELIRFNRLLSYIRKSLVNVGKAVVGQIAMIP----- 4169
            ||.:  .:.:..|          ..|..|.|:..||    ||........||:|..|..|
Mouse  4433 QLQQ--RLAQAKK----------RLVALQALLTNNR----IRSGQCVTPWAVLGPNARRPLEGFL 4481

  Fly  4170 ELERTHASMVIGKLPAD------WLKKSYPSLKPLGSYVSDLLARLAFFQEWIDN---GEPMVY- 4224
            |.|......::|.|..|      .||...|......:.|:..|......|.|..:   |..:.:
Mouse  4482 ETEVLELKHLVGTLLCDLDCLLQQLKGGTPCTSSRCAKVAQALWAGHLPQPWRSHALAGSQLPWL 4546

  Fly  4225 WI-----SGFYFTQSFITGVLQNYSRKNRF----------QIDMILIEFAVTKFEV---QVPG-- 4269
            |:     .|....:...:|:.:|.::..|.          ::.:.|...||.:..|   .:||
Mouse  4547 WLRQLSRRGHLLIRYLDSGMSENANKPERIFHLSAFRHPGRLLLALRWEAVLENSVHNPNLPGHQ 4611

  Fly  4270 ------------------------------TPDIGAYIRGIFIEGARWNRKTKEVDESFSKVLFD 4304
                                          .|.:|..:.|:.::.|.|::....:.:|||....
Mouse  4612 DSISGSLPPKWQELSNHPLHIWVENGPNPKVPKMGLLLTGLQLQHAEWDQTDGALQDSFSSQPC- 4675

  Fly  4305 TLPVIYLRPVLKALEDLPRSTAGGEPETIYDCPVYKTSERRGVLSTTG-HSTNFVMYLQLRCSRK 4368
            .||.:.:....:..:|.|.|...|    :|.||||.|    |...||. ||.|.:|:|.|.....
Mouse  4676 PLPPVSISTQARRGKDAPVSAGLG----MYSCPVYMT----GPFGTTKLHSKNILMHLPLPTRLS 4732

  Fly  4369 PMHWINR 4375
            |...|.|
Mouse  4733 PDTCIQR 4739

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dnah3	NP_647937.2	DHC_N2	1086..1489	CDD:285579	90/499 (18%)
		P-loop_NTPase	1620..1847	CDD:304359	64/274 (23%)
		P-loop_NTPase	1934..2079	CDD:304359	33/159 (21%)
		P-loop_NTPase	2264..2522	CDD:304359	65/321 (20%)
		P-loop_NTPase	2613..2916	CDD:304359	60/322 (19%)
		MT	2929..3272	CDD:289543	71/356 (20%)
		AAA_9	3304..3519	CDD:289547	58/331 (18%)
		Dynein_heavy	3659..4373	CDD:281078	177/839 (21%)
Dnhd1	NP_001357732.1	DHC_N2	1021..1469	CDD:369852	86/460 (19%)
		AAA_6	1652..2005	CDD:372306	85/375 (23%)
		Dynein_AAA_lid	2187..2347	CDD:375381	32/186 (17%)
		P-loop_NTPase	2366..2533	CDD:393355	40/189 (21%)
		P-loop_NTPase	2869..3119	CDD:393355	57/306 (19%)
		MT	<3198..3468	CDD:289543	61/300 (20%)
		AAA_9	<3663..3801	CDD:372311	39/164 (24%)
		Dynein_heavy	4103..4222	CDD:367303	26/118 (22%)
		Dynein_C	<4519..4744	CDD:375627	48/230 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810