DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dnah3 and Dnah7a

DIOPT Version :9

Sequence 1:	NP_647937.2	Gene:	Dnah3 / 38586	FlyBaseID:	FBgn0035581	Length:	4385	Species:	Drosophila melanogaster
Sequence 2:	XP_006496242.1	Gene:	Dnah7a / 627872	MGIID:	2685838	Length:	4046	Species:	Mus musculus

Alignment Length:	4135	Identity:	1801/4135 - (43%)
Similarity:	2487/4135 - (60%)	Gaps:	279/4135 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   343 LQPVDPDDQKIKMLAKYRVELARAEK---------LFTLKI---QKRYQCLLKSMSIVQL---AT 392
            |..:| ||:.....::.:|:....|:         ::..||   ||..:.|..:::.|.:   ..
Mouse    97 LDQID-DDRSAPSTSRSKVKSPHKERENFKSTLPSIYRSKIKSPQKERENLRSTLAKVIMQKDGG 160

  Fly   393 YPSHLIRKAFRRINPRSALLQD--AYQFIVKEKRDWPKLPP-EVILMDYLFVGDRGVRQDLAIL- 453
            ..|.:|.::.......||..:|  .|.:.:::..|...:.| |...::::.   :.|.:.|.:|
Mouse   161 LESDVIDESGIPKETTSATEKDISRYYYYIRQGLDTDHVAPMEDSWLEHVL---QLVPEHLKVLT 222

  Fly   454 --IIVCLIDLQEDFRHYVKRSFLNYLLSSNMER----RRLQLEREPPEFPILTISPPVSWRSNLL 512
              |.|...:::||:...||:|.::::|....|:    :..:|.....|..:|    |..||.:.|
Mouse   223 NSIKVLSDEIREDYLLSVKKSIVDFVLKDPREKDDDGKITELPPHRAEMEVL----PKPWRRSFL 283

  Fly   513 RGKARIGEVLMTTHPTVQALNRLWHDLYEDLVVVDLGQLLLAQRPLDADTVQVFIEKSCADVRDL 577
            ...:.|.:.|...:|.:.|:..|||..::.|.:||:.:....|..|:....|..:.|.....::.
Mouse   284 SACSYIRDHLNAMNPMMLAVLDLWHSTFKKLRLVDIEEFHSCQDALELSEFQNIVIKHMESAKET 348

  Fly   578 LLNDWLPRCADLMNEMRGTWKDLVPMSGKYGGRAAMLFRCIHSAMSRHLNSLISKSINYLFKVLC 642
            ||..|.|...::.|:  |..|..:| :||...:....|.|..:.|:..|..||..|:.....::.
Mouse   349 LLKTWFPEVQNIFNQ--GNKKKQLP-TGKSTAKLDSFFNCAATLMTLQLQDLILVSMQDFTDLIA 410

  Fly   643 AFKGGNRIEKYSMFDAKLKRIPLMTLIASVVGAHFDHEPINMGPGVRPASNIYVYDEDDADPFQQ 707
            ......|:.::..|        :|.|:       .|.|.|..                      :
Mouse   411 QPLESIRVFEHPGF--------IMRLV-------LDKEAIKF----------------------E 438

  Fly   708 PQVNQFVENVPDIDDVAQFELDHSNKLYIYPYMQELPRIFTEHFKSILAVGYEIPRLEFVM---- 768
            |:.|::::::                :.||..|             |.||.: :||:|..:
Mouse   439 PEFNEYIDSL----------------INIYEIM-------------IKAVSF-VPRVETKLYSQW 473

  Fly   769 -SGGEPETKG--FLHFIDEDHVDFLELCEKVEQIVKVNWQGVHVYLKPVYKYYFGLFQKLILPMV 830
             |..:|.|..  .|:.|.:.|.      ||:.:::.........:||...||.|.:..|....:.
Mouse   474 ESKSKPTTLKPIILNEIIDTHK------EKIREVILRESVAPTEHLKMYDKYQFLITGKAERDID 532

  Fly   831 QKVWTENN----LPELGAVQELLKKLQAVSDTTYYLRDFIPLNLFMLDNRHVKLSLRMYVREIYD 891
            :.::...|    :.|:...|:|.:::|..|..|      :.|.:|.:   |.:..:|..|:.. |
Mouse   533 ELLFQNQNYERLIEEIRKYQKLGEEIQYTSQKT------VCLGMFEM---HCEELIRSLVKRA-D 587

  Fly   892 FIIDFYKALNWNE----NRAICEELEEMSMKAGERPEETPEVVALQNYINDCREMRIFAIKDEIK 952
            .|.....|..:.:    |..:|:|.|:::.||...|..|.|::.::.::.......:..:...:.
Mouse   588 VICGKLIAKMFRDHQEVNTMLCDEFEKIAEKALSTPLNTAELMEMKAHVQKLETTDMLELGQRLV 652

  Fly   953 NVLKRVVFLLTHTYLSSDELHLNSRTFILPGELEEVLDLSAARLAVVRDNLEL---ALRERRMEF 1014
            :....:.||:.....|..::.||...|...|.:.|:.|   ....::::..||   .|:.|...|
Mouse   653 DSKICLAFLIECVNFSPADIRLNKSVFQWYGRMGEIFD---EHRKIIKEKTELYQEFLKFRCERF 714

  Fly  1015 -EKLLAQEKRTMDGFRIREIRDVLTLEELKERVDTVDLLFTTIENLSREAKAINTEETLLQIDVS 1078
             |:|.:..|:..:.....::.||      :..:....:|...::..:.:....|.||.......|
Mouse   715 VEELESYAKQVEEFHAFGDLLDV------QRYLQKAQVLNGKLDAAADKIDQFNAEEEAFGWVPS 773

  Fly  1079 AFPLLAEIIEKMEPIEKLWKTSYEFEKDYLIWMFERFECLNADGVREQVENMHKIMYKLSRQLAY 1143
            |:|...:|.:.:.|...|::|:.||...:..|....:..:|.|.|...|.|..:.:|||.:....
Mouse   774 AYPQRKKIQDALNPYLHLYETAVEFSTKHRGWTEGPYHKVNPDQVEADVGNYWRGLYKLEKVFHD 838

  Fly  1144 NPVAKRAAEQMRMKIEKFRVYLPVLDSICRHGLEKRHWDQISKILGRKVNPKLFPTLKDMIDVDI 1208
            :|.|....:::...:|:|:.|:|::...|..||..|||:.:|.|:|..:.|....|:...||:::
Mouse   839 SPNALAMTKKVHSMVEEFKQYIPLIQVFCNPGLRPRHWEAMSTIVGYPLQPSDDSTVFSFIDMNL 903

  Fly  1209 MSILPQLEEIANAAGKEYDLNNGLRIMQADWRDVMFEVLQYRDSDTHILASLDDIQTLLDDHIMR 1273
            ...|.:...|:.||.|||.|...:..|..:|..:.|.:|.||:|.|:||:|:||||.||||||::
Mouse   904 EPFLDRFGSISEAASKEYSLEKAMDKMMTEWDSMEFVILPYRESGTYILSSVDDIQMLLDDHIIK 968

  Fly  1274 TQAMKRSPFITALGSKADDWEARLLLIQNIIDAWTQVQITWMYLEPIFSSEDIMRQMPLEGRNFK 1338
            ||.|:.||||.....:..:||.:|||:|.|:|.|.:||.||:||||||||.|||.|||.|||.|.
Mouse   969 TQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSRDIMSQMPEEGRRFT 1033

  Fly  1339 AVDKLWRKIMKHTLKDRHVMAATEYPEMLEVFTKAIEDLETVTKGLNTYLEQKRLFFARFFFLSN 1403
            ||||.||.:||..::|:.|:|......|||...|:.|.||.:.||||.|||:|||||.|||||||
Mouse  1034 AVDKTWRDVMKTVVQDKQVLAVVTIERMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSN 1098

  Fly  1404 DELLEILSETKDPMRVQPHLRKCFEGIGSLTFDDNMEIVEMVSDEEERVALVRKINPQLANGLVE 1468
            |||||||||||||.||||||:||||||..:.|.:.::|..|.|.|.|.|.||..|:...|.|.||
Mouse  1099 DELLEILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEGEVVELVDTISTAKARGQVE 1163

  Fly  1469 MWLKEVEMVMLDSVKEQMREAWEDYAMVERISWVVSWPGQVVQGISCMAWTYEVEEAIET--KEL 1531
            .||.|:|..|:.|:.:.:|:|...|....|||||..||||.|..:|...||.||:.||..  :.|
Mouse  1164 KWLVELERTMIKSIHKVIRDAIVAYTKTSRISWVRDWPGQTVLCVSQTFWTVEVQIAIPEGHRAL 1228

  Fly  1532 PAYLEKSNLQIADLVQLVRTDLQAGVRIAVEALIVLDVHDRDVVKYLTDCRITNIQDFDWISQLR 1596
            ..||.|.|.||.|:|.|||..|....|:.:.||:|||||.|||:..|.|.:|::..||.|:||||
Mouse  1229 EGYLAKCNHQIDDIVTLVRGKLSKQNRVTLGALVVLDVHARDVLASLVDKKISDDSDFQWLSQLR 1293

  Fly  1597 YYWKVNEKNEDWVCVSMVVTDVEYGMEYLGNLPRLVVTPLTDRCYRTLMGALKLCLGGAPEGPAG 1661
            |||:.|...     ..|:...:.||.|||||.||||:|||||||||||.|||.|.||||||||||
Mouse  1294 YYWQENNLE-----TKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAG 1353

  Fly  1662 TGKTETCKDLAKAVAKKCVVFNCSDGLDYKALGKFFKGLAQSGAWACFDEFNRIELEVLSVVAQQ 1726
            ||||||.|||||||||:||||||||||||.|||||||||...||||||||||||:||||||||||
Mouse  1354 TGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQ 1418

  Fly  1727 ILTIQRAIGRKVVKFFFEDTMLKLDPTCSIFITMNPGYAGRTELPDNLKVLFRTVAMMVPDYAMI 1791
            ||||||.|........||.|.|||||||::|||||||||||:|||||||.|||||||||||||||
Mouse  1419 ILTIQRGINAGTDLLVFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMI 1483

  Fly  1792 GEITLYSNGFDMARNLSQKIVQAYKLCSEQLSSQSHYDYGMRAVKSVLLASASLRRLYVDLPEPE 1856
            .||.|||.||..||.||.|||..|:|||||||||.|||||||||||||.|:.:|:..|.:..|..
Mouse  1484 AEIVLYSCGFVTARPLSIKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEI 1548

  Fly  1857 IVLRAIVDVNLPKFLEQDISLFIGIYMDLFPGVELPMPQRGDILKWLHINLADRNLQATPWYLEK 1921
            ::||:|:||||||||..|:.||.||..||||||:||.|...|:|..:..|....|||.|.::.||
Mouse  1549 LLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPKPDYNDLLAAIRDNCHSMNLQMTDFFSEK 1613

  Fly  1922 ILQIYEMLLVRHGLMIVGGSMGGKTTAYQVLAQTLRNVSTDEEATLKEFPVTFRIINPKAITMGQ 1986
            |||||||::||||.||||...||||:||:|||..|.::.  |:..::|..|...::|||::||||
Mouse  1614 ILQIYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDIC--EKGLMEENKVQITVLNPKSVTMGQ 1676

  Fly  1987 LYGRFDPVSHEWYDGVLAKTFREQVQGPKGERAWVMFDGPVDAVWIENLNTVLDDNKKLCLMSGE 2051
            |||:||.|||||.|||||.:||........:|.|::||||||||||||:||||||||||||||||
Mouse  1677 LYGQFDLVSHEWSDGVLAVSFRAFAASSTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGE 1741

  Fly  2052 IMQMTKLMNMMFEPADLEQASPATVSRCGMIYMEPSQLGWRALHKSFINVLVNKVGLGDIYMTLF 2116
            |:||:..||::|||.|||.||||||||||||||||..||||.|..|:||.|...|.:  |.....
Mouse  1742 IIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMVSWINTLPQSVSI--IQKEFI 1804

  Fly  2117 EDMTEWLVPAALEFLPQCKQMLELSPIYQ-------YQTFSRFFLHFLEKHKQFNQ------AWF 2168
            |.:.:.:||.::||:.  :...||||...       ......|...|.:::||..:      :..
Mouse  1805 EGLFDRMVPLSVEFIR--RHTKELSPTSDTNLVRSLMNLIDCFMDDFADENKQKERNDRESFSLL 1867

  Fly  2169 QQMFLFCFAWAYCSALTGQGQKTFDALLRKVIYGSNENFPKPKYFSLNRGQM---------FPEK 2224
            :.:|||...|:..:..|...:..||.:||:::.|...|..:.|:..|:..:.         ||||
Mouse  1868 EGIFLFSLIWSVGATCTDDDRLKFDKILRELLEGPISNLTRNKFKLLSGTEQTSSKVFIVPFPEK 1932

  Fly  2225 LLFLDYRFDEAENWWTWQKSDDSASTTSNFPENAQISELIVPTKETGYISYWQEFCISKSYAMLV 2289
            ....||:| ..|....|.|.....:.|...|::.|.:|:||||.:|...|.......:.....:.
Mouse  1933 GTIYDYQF-IPEGLGRWDKWIKDLADTPPIPKDVQFNEIIVPTLDTIRYSALMNLLTTHQKPSIF 1996

  Fly  2290 VGPTGTGKSAIITSNLLAMPKFANLVN-------VINFSARTSAQMVQDTIMSKLDRRRKGVFGP 2347
            |||||||||..|.:.||      |.:|       ::||||:|:|...|:.||||||:||||||||
Mouse  1997 VGPTGTGKSVYIINFLL------NQLNKDIYKPLIVNFSAQTTAAQTQNIIMSKLDKRRKGVFGP 2055

  Fly  2348 SLGKKCTVFCDDVAMPSKDTYGSQAPLELLRTWLDHGYWSDLVDTTKIELVDMTLMCAMGTLGGS 2412
            .|||:..||.|||.||:::.||:|.|:||||.||||..|.||.|.:.|:|||:.:|||||..||.
Mouse  2056 PLGKRMIVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSVIKLVDIQIMCAMGPPGGG 2120

  Fly  2413 -NFIFPRLYRHMFVVAVDSFEDSTIVRIFTTIGDWHFSKGY--PEKVALLSRGLSEAMVSVYRDA 2474
             |.|.||..||..:|.::.|.:.::..||:.|..||....|  |:....|:..:....:::|:||
Mouse  2121 RNPITPRYMRHFNIVTINEFSNKSMFTIFSRILAWHLRTCYKFPDDFLDLTTQIVNGTMALYKDA 2185

  Fly  2475 IRSFLPTPAKSHYSFSLRDITRVFQGIVMVPPKRMPDPEKLGRLWAHETYRVFYDRLVDQQDRDR 2539
            :::.|||||||||.|:|||.:||.||:.:..|:...:.|.:.|||.||..||:||||||..||..
Mouse  2186 MKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETAENKEAIKRLWVHEVLRVYYDRLVDNADRSW 2250

  Fly  2540 LLVMAVDACKSNLRFPLEQAFGERIEPGEKLT--DNDLRNLFYGNYMEPDAEPKFYDEGDTYEKL 2602
            |:....:..|:.::......| :.::.....|  ::|||:|.:.::.:|..|...|.|....:.|
Mouse  2251 LINYIQEILKNYMQEDFHDLF-KNLDFNHDGTVEEDDLRSLMFCDFHDPKREDFGYREIANVDAL 2314

  Fly  2603 EKLMKYYLREYNSFSSTPMDLVMFRFAIEHVSRVSRVLQMPRGNILMVGMGGSGRRSSARLAAYI 2667
            ..:::.:|.|||:.|..||:||:|||||||:||:||:|:.||.:.|:||:|||||:|..||||::
Mouse  2315 RMIVEGHLDEYNNMSKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQSVTRLAAHM 2379

  Fly  2668 ADCRLMTVQVSKSYTITDWRDDLKKILMSASFNLNHTVFLFSDAQATDEGYVEDINGILNTGDLP 2732
            ||..|..|::||.|...:|.:|||.||...:.:....||||:|.|...|.::||:|.:||.|::|
Mouse  2380 ADYSLFQVEISKGYGSHEWHEDLKVILRKCAESDMQGVFLFTDTQIKRESFLEDVNNLLNAGEVP 2444

  Fly  2733 NLYQLEDKATIMENMANVAKQ--LGKILDTLPSEVYAYYIDRIREQLHIALAFSPIGDSFKERIR 2795
            ||:.|::|..|.|.|..:.:|  ..|..|..|..::..:||..|.|||:.||.|||||:|:.|:|
Mouse  2445 NLFALDEKQEICEKMRQIDRQRDKSKQTDGSPIALFNMFIDCCRNQLHVVLAMSPIGDAFRIRLR 2509

  Fly  2796 VYPSLINCCTIDWYMPWPEEALSRVGVYFVSSMNLNRPHGEETQEPVQSKDAADPDEEEVRRETV 2860
            .:|:|:|||||||:..|||:||..|...|:..:.::                     ||:|.
Mouse  2510 KFPALVNCCTIDWFQSWPEDALEAVASRFLEDIEMS---------------------EEIRE--- 2550

  Fly  2861 GVEREQTQLEADLVDCVMYFHQSVVDASEKCYLELNRRNYVTPSAYLELLKAFRTFYTRKLDEIT 2925
                       ..:|....||.|.::.|...:.||.|.|||||::||||:..|:....:|.:|:.
Mouse  2551 -----------GCIDMCKRFHTSTINLSTSFHNELQRYNYVTPTSYLELISTFKLLLEKKRNEVM 2604

  Fly  2926 RLRDRYTTGLEKLDFAAGQVGEMQTNLYDLQPKLKVLSEETDRIMVNIERETAEAEKKKEVVGAD 2990
            :::.||..||:|||.|:.||..||:.|..|.|:|||.|.|.|.:|:.||||:.|..|.:::|.||
Mouse  2605 KMKRRYEVGLDKLDSASSQVATMQSELEALHPQLKVASREVDEMMIIIERESMEVAKTEKIVKAD 2669

  Fly  2991 EAAANEAAAAAQAIKDDCETDLAEAIPAMEAALEALNTLKPADIFIVKSMKNPPYGVKLTMEAVC 3055
            |..||:.|.||:||||:|:.|||.|:|.:|:||.||:||...||.:|||||:||.||||.|||||
Mouse  2670 ETVANDQAMAAKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAVC 2734

  Fly  3056 VIRGIKPDRKPDP--SGHMVEDYWGPSMRMLSDMKFLDSLKTFDKDNIPPPIIKRIREKYIADRD 3118
            :::|||.|:.|||  ||...||:|||:.|:|.|::||.||..:|||||||..:..||:.||.:.|
Mouse  2735 ILKGIKADKIPDPTGSGKKTEDFWGPAKRLLGDIRFLQSLHEYDKDNIPPAYMNIIRKSYIPNPD 2799

  Fly  3119 FVPEKIKAASMACEGICRWVRAMDVYDKVARIVMPKKAALAEAEGELSQQMEKLNAKRAELQVIL 3183
            ||||||:.||.|.||:|:||.|||.|||||:||.|||..||.|||:|...||.|..|:|.|..:.
Mouse  2800 FVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGKLKVAMEGLRKKQAALHEVQ 2864

  Fly  3184 DKLQKLNDFFAEKSREKKRLEDEIDNCEKKLNRAEKLLGGLGGEKTRWSEAAKNLHESISNIVGD 3248
            |||.||.|......::|..||.::|.|.|||.|||:|:|||||||||||.:|..|.....|:.||
Mouse  2865 DKLAKLQDTLELNKQKKADLEHQVDLCSKKLERAEQLIGGLGGEKTRWSNSALELGHLYINLTGD 2929

  Fly  3249 VLLAGGCTAYLGYFTTEYRVNILDDWNALCKRKHIPSSETFSLATTLGHPMTIRAWSLAGLPADN 3313
            :|::.|..||||.||:.||.|....|:..||.:.||.|:.:||..|||..:|||||::||||:|:
Mouse  2930 ILISSGVVAYLGAFTSNYRQNQTKQWSQSCKERDIPCSDDYSLMGTLGEAVTIRAWNIAGLPSDS 2994

  Fly  3314 FSVENGIIVTNSSRYSLLIDPQVQANKWIKNMEKNNNLKVIKQSDANYMQVLELAITFGQPVLIE 3378
            ||::||||:.|:.|:.|:||||.|||||||||||.|:|::||.||.:|::.||..|.||.|||:|
Mouse  2995 FSIDNGIIIMNARRWPLMIDPQGQANKWIKNMEKTNSLQLIKLSDPSYVRTLENCIQFGTPVLLE 3059

  Fly  3379 NVGEKLDSNLTPILEKNVIKHKGGLFIKSGDQMIEYNPNFRLYITTCLRNPRYPPEVMVMVTVLN 3443
            ||||:||..|.|:|.|...|..|...|:.||..|||:|:||.||||.||||.|.||..|.||:||
Mouse  3060 NVGEELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYSPDFRFYITTKLRNPHYLPETSVKVTLLN 3124

  Fly  3444 FMITEQGLREQLLAIVVAHERPDLQEKKEQLIIESARNRDALYTIESKILEVLSTSEGNVLEDEN 3508
            ||||.:|:::|||.||||.|||||:|:|:.||::.|.|:..|..||.|||||||.||||:||||.
Mouse  3125 FMITPEGMQDQLLGIVVARERPDLEEEKQALILQGADNKRQLKEIEDKILEVLSLSEGNILEDET 3189

  Fly  3509 AINILSSSKILSEDIQEKQVIAVATEIEIDAARQQYIPVSKHSAILFFCISELANVDPMYQYSLS 3573
            ||.||||||.|:.:|.:||.:|..||.:||..|..|.|::.||:||||.|::|||::|||||||:
Mouse  3190 AIKILSSSKSLANEISQKQEVAEETEKKIDITRMGYRPIAIHSSILFFSIADLANIEPMYQYSLT 3254

  Fly  3574 WFLNLFVNTILKAPKSDQLSERLKNLNDYFTKSIYTNVCRSLFEKDKLVISLVMCLGILVSQGRV 3638
            ||:|||:.:|..:.|||.||:||:.|.|:||.|:|.|:||||||||||:.|..:.:.:|:....:
Mouse  3255 WFINLFILSIENSEKSDILSKRLQILRDHFTYSLYVNICRSLFEKDKLLFSFCLTVNLLIHDNAI 3319

  Fly  3639 EKAALLFFLTGGIGYKTIPPNPLGAWLPDKSWASVCKAADLEGLKNLPQMMETYSDEWHNFYDAS 3703
            .|....|.||||||......||. .|||.|||..:|:..||...|.:.:......|.|...||:.
Mouse  3320 NKTEWRFLLTGGIGLDNPYTNPC-TWLPQKSWDEICRLDDLPAFKTIREEFMRLKDGWKKVYDSM 3383

  Fly  3704 NPDQLQLPAP-HNTVNDMYFLIVIKSLRPDKLVPAVRAFITRNLDRSFVEPPPFDLAASFADSSP 3767
            .|.....|.. .|..||...:::|:.|||||::|.::.||.:.|.|||:||||||||.:|.||:.
Mouse  3384 EPHHEMFPEDWGNKANDFQRMLIIRCLRPDKVIPMLQEFIIKKLGRSFIEPPPFDLAKAFGDSNC 3448

  Fly  3768 KIPLVFLLSAGSDPMASLFMFAKQRNMY--DKLKTISLGQGQGPRAEKMIMEAARHGQWVVLQNC 3830
            ..||:|:||.|:|||.:|..||..:. |  .||.::||||||||.|.||:.:|.:.|.|||||||
Mouse  3449 CAPLIFVLSPGADPMNALLKFADDQG-YGGSKLSSLSLGQGQGPIAMKMLEKAVKDGTWVVLQNC 3512

  Fly  3831 HVAISWMGDLERICNDTTLTDGANHDYRLWCTSYPSAVFPVSVLQNSVKMTNEPPKGLRANMHRS 3895
            |:|.|||..||::|.:.: .:..:.|:|:|.|||||..||||||||.||||||.|||||||:.||
Mouse  3513 HLATSWMPTLEKVCEELS-AESTHPDFRIWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRS 3576

  Fly  3896 FTSDPLMRDKFFTNAFLFSDSANKC-----WLRGVFALVFFHAVVQERREFGPLGWNIPYEFNES 3955
            :..||:...:||          ..|     :.:.::.|.||||:|||||:||||||||||||||:
Mouse  3577 YLMDPISDPEFF----------GSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNET 3631

  Fly  3956 DLKISLLQLKMFINQSQSIPFRGHVYLTGECNYGGRVTDDKDRRLILSLLNMIYNPNTIEEDNYA 4020
            ||:||:.||.||::|.:.:|:....|:|||||||||||||.|||.:.|:||..:....:|...|.
Mouse  3632 DLRISVQQLHMFLDQYEELPYDALRYMTGECNYGGRVTDDWDRRTLRSILNKFFCTELVENPQYK 3696

  Fly  4021 LSQSGTYRVPLSPTRLNSIEYVSSFPLSPHPEVYGLHENADINRNVKETNALISGVLLTQTDLMA 4085
            ...||.|.||.|....:.|:|..:.||.|.|||:|::.||||.::..||..|...:||||:
Mouse  3697 FDSSGIYFVPPSGDHKSYIDYTKTLPLIPAPEVFGMNANADITKDQSETQLLFDNILLTQS---- 3757

  Fly  4086 SVKASSSGGAKEDPAI-AICKQVLKQLPEEFNIDEVSKTYPVIYTNSMNTVLRQELIRFNRLLSY 4149
              .:|.||....|..: .:...:|.:||..|:::...:.||..||.||||||.||:.|||:||..
Mouse  3758 --HSSGSGTKSSDEVVNEVAGDILGKLPNNFDVEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLIT 3820

  Fly  4150 IRKSLVNVGKAVVGQIAMIPELERTHASMVIGKLPADWLKKSYPSLKPLGSYVSDLLARLAFFQE 4214
            ||:|.:|:.|||.|.:.|..|||...:|::..|:||.|:.|||||||||||||:|.|.||.|.|:
Mouse  3821 IRESCINIQKAVKGLVVMSTELEEVVSSILNVKIPAMWMGKSYPSLKPLGSYVNDFLERLKFLQQ 3885

  Fly  4215 WIDNGEPMVYWISGFYFTQSFITGVLQNYSRKNRFQIDMILIEFAVTKFEVQVPGTPDIGAYIRG 4279
            |.:.|.|.|:|:|||:|||:|:||..|||:||....||::..::.|.. :.:....|:.|.||.|
Mouse  3886 WYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKFTIPIDLLGFDYEVMD-DKEYKKAPEDGVYIHG 3949

  Fly  4280 IFIEGARWNRKTKEVDESFSKVLFDTLPVIYLRPVLKALEDLPRSTAGGEPETIYDCPVYKTSER 4344
            :|::||.|:||||::.||..|||:||:||::|:|..|:  |:||..:       |..|:||||||
Mouse  3950 LFLDGASWDRKTKKLAESHPKVLYDTVPVMWLKPCKKS--DIPRRPS-------YVAPLYKTSER 4005

  Fly  4345 RGVLSTTGHSTNFVMYLQLRCSRKPMHWINRGTACLCQLD 4384
            ||.|||||||||||:.:.|.......|||.||.|.||||:
Mouse  4006 RGTLSTTGHSTNFVIAMILPSVHPKEHWIGRGVALLCQLN 4045

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dnah3	NP_647937.2	DHC_N2	1086..1489	CDD:285579	184/402 (46%)
		P-loop_NTPase	1620..1847	CDD:304359	183/226 (81%)
		P-loop_NTPase	1934..2079	CDD:304359	90/144 (63%)
		P-loop_NTPase	2264..2522	CDD:304359	119/267 (45%)
		P-loop_NTPase	2613..2916	CDD:304359	125/304 (41%)
		MT	2929..3272	CDD:289543	189/344 (55%)
		AAA_9	3304..3519	CDD:289547	132/214 (62%)
		Dynein_heavy	3659..4373	CDD:281078	340/722 (47%)
Dnah7a	XP_006496242.1	DHC_N2	779..1184	CDD:369852	184/404 (46%)
		DYN1	894..3688	CDD:227570	1446/2860 (51%)
		AAA_6	1312..1638	CDD:372306	236/325 (73%)
		AAA_8	2333..2593	CDD:372310	120/294 (41%)
		AAA_9	2985..3201	CDD:372311	132/215 (61%)
		Dynein_C	3742..4042	CDD:375627	146/315 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56321
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000321
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1547
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.720