Protein Alignment Dnah3 and CG14651

DIOPT Version :9

• Sequence 1: NP_647937.2
• Gene: Dnah3 / 38586
• FlyBaseID: FBgn0035581
• Length: 4385
• Species: Drosophila melanogaster
• Sequence 2: NP_649475.3
• Gene: CG14651 / 40568
• FlyBaseID: FBgn0037254
• Length: 1079
• Species: Drosophila melanogaster
• Alignment Length: 1156
• Identity: 217/1156 - (18%)
• Similarity: 379/1156 - (32%)
• Gaps: 421/1156 - (36%)

  Fly   348 PDDQKIKMLAKYRVELARAEKLFTLKIQKRYQCLLKSMSIVQLATYPSHLIRKAFRRINPRSALL 412
            |||.:.|         ..|||..         |::.......:..|....|        ||:. |
  Fly    31 PDDSQFK---------REAEKAI---------CIMPPRPGTTMMNYQELYI--------PRNQ-L 68

  Fly   413 QDAYQFIVKEKRDW---------------PKLPPEVILMDYLFVGDRGVRQDLAILIIVCLIDLQ 462
            .|.| :.::|.:.|               |.:.|:||...|  |..|.:.:|         :::.
  Fly    69 TDVY-YPIQEAQRWLTLMDKMGKAHRFPLPTILPKVIQTRY--VPKRHLPKD---------VEVD 121

  Fly   463 EDFRHYVKRSFLNYLLSSNMERRRLQLERE----------PPEFPI-------LTISPPVSWRSN 510
            ...|.|.|.:.:|.|..:.:....||...|          |.:||:       ..|:.|.:|...
  Fly   122 RRRRQYQKINLVNELAKAGLTDDVLQPTEEQYNVMSEFAFPHKFPLSYFDDSNFDINSPAAWFEL 186

  Fly   511 LLRGKARIGEVLMTTHPTVQA-LNRLW-----------HDLYEDLVVVD--------LGQLLLAQ 555
            .:.|.|..........|..|: ||..|           .||:..|.:.|        |..:.:|:
  Fly   187 GVVGDAHYPLPAKAYLPYNQSLLNCQWGMAAVTAHHEDSDLWTLLSLEDGCTYTVPKLQFMFMAE 251

  Fly   556 RPLDADTVQVFIEKSCADVRD------LLLNDWLPRCADLMNEMRGTWKDLVPMSGKYGGRAAML 614
            .|      ..:|::..|.|.:      |:|.:.:..|. |..::..|              ....
  Fly   252 DP------HKYIKRLQAAVHERHKGEQLMLMELIVDCV-LHEDIEST--------------VFYS 295

  Fly   615 FRCIHSAM-----SRHLNSLISKSINYLFKVLCA-----------------FKGGNRIE----KY 653
            |:.|.|.:     |......:...:|.:|:.|.|                 |:..|..|    .:
  Fly   296 FKPIESVLQAAKVSEQCKRRLRSEVNLVFERLMALYELEQFILKMPKEFPQFRNINLKEFLPRSF 360

  Fly   654 SMFDAKLKRIPLMTLIASVVGAHFDHEPINM----GPGVRPASNIYVYDEDDADPFQQPQVNQFV 714
            ::..:..:|:.|..|..::....:|:...::    | |:...:.:.:             ..|::
  Fly   361 AVDVSGKERLELQALGITMQEKRYDYLKASLFYCVG-GIEAMAGVAI-------------ECQYI 411

  Fly   715 ENVP----------DIDDVAQFELDHSNK----LYIYPYMQELPRIFTEHFKS------------ 753
            |.:.          .:.|..|.:..||:.    |.:| :.|:|..:.|...::
  Fly   412 ETLSIFICSFSKPLALVDFLQAQEAHSDNVATFLKVY-WPQQLTTVITVVLRALGKGWLDISLNT 475

  Fly   754 ------------ILAVGYEIPR-LEFVMSGGEPETKGFLHFIDEDHVDFLELCEKVEQIVKVNWQ 805
                        ||.|.:.:.. :|.::   |.....|.||:.:..:.||||        |.|::
  Fly   476 WTVYLMCKISRFILQVKFRMQESMEVLL---ETSLMNFSHFVCDPCLQFLEL--------KSNYK 529

  Fly   806 GVHVYL-------KPVYKYYFGLFQKLILPMVQKVWTENNLPEL--GAVQELLKK-------LQA 854
            ..:.|:       |||:....|:.:.      :||:...:..|.  |.| |:.||       ::.
  Fly   530 WTNNYIDTEFPFQKPVFAMTLGISED------RKVFYSTDPDEFQPGLV-EIFKKCLEKSSGVRC 587

  Fly   855 VSDTTYYLRDFIPLNLFML-----------DNRHVK-------LSLRMYVREIYDFIIDFYKALN 901
            :..:......|.| ||::|           :|..:|       |.||.|.| :|:..|||| .||
  Fly   588 IDGSVMSFLKFAP-NLYILTVELIEDRFLRENELLKNCYAKAVLPLRAYAR-LYERFIDFY-LLN 649

  Fly   902 WN---------------------ENRAICEELEEM---------------SMKA----------- 919
            .|                     ||:.:.|||.|:               :||.
  Fly   650 VNTYMQAYAQAHKPSSEVKRDILENKRLKEELREILPAFITIGPFYINVDTMKQFMIKKRIEVVR 714

  Fly   920 ------GERPEETPEVV---ALQNY---------INDCREMRIFA-----IKDEIKNVLKRVVFL 961
                  .:|..||.||:   .|:.:         |....|:|.||     :.||:|..::  |..
  Fly   715 RIFEYYVDRMYETNEVLLDRCLEMFRRIAERPISIEHLYEIRDFAQTVPDLVDELKADIQ--VMW 777

  Fly   962 LTHTYLSSDELHLNSRTFILPGELEEVLDLSAARLAVVRDNLELALRERRMEFEKLLAQEKRTMD 1026
            |.:..|.|...:|:...|.:...:.........||:.::|       |::::.|..|........
  Fly   778 LEYDLLDSFFYNLSDHQFAMKWNVYAWPHQIMVRLSTLKD-------EQKVDIEDFLRLHASECQ 835

  Fly  1027 GFRIREIRDVLTLEELKERVDTVDLLFTT----------------IENLSREAKAINTEETLLQI 1075
            .|..|       ||.|.:.|....|.|.|                |:.|.:.::.:...:.|.::
  Fly   836 AFEER-------LESLNDEVQAYSLAFNTNRAQETSVDIKKTWALIKELEKVSQTLQFRQELFEL 893

  Fly  1076 DVSAFPLLAEIIEKMEPIEKLWKTSYEFEKDYLIWMFERFECLNADGVREQVENMHKIMYKLSRQ 1140
            :..:...|..||....|.:.||                 :.|.|              ..||...
  Fly   894 EPLSVEFLESIIASFTPYKNLW-----------------YGCAN--------------FLKLEDA 927

  Fly  1141 LAYNPVAKRAAEQ-----MRMK-----------------------IEKFRVYLPVLDSICRHGLE 1177
            ...||:|:...|.     ||::                       |.|...::||.:||.....|
  Fly   928 TLGNPIAQLDLEDVWNNLMRLRDELNESMKIFHEKVEIMDVAKTFIAKIDDFVPVYNSIKDIRNE 992

  Fly  1178 K---RHWDQISKILGRKVNPKLFPTLKDMIDVDIMSILPQLEEIANAAGKE 1225
            .   .||.::|.|.|:::...:....:.:|...|:.:||::..|:..|..|
  Fly   993 NWMYIHWQELSAITGQEIKYSVAMNYQYLIRKGILDVLPEVHIISEKANNE 1043

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dnah3	NP_647937.2	DHC_N2	1086..1489	CDD:285579	34/171 (20%)
		P-loop_NTPase	1620..1847	CDD:304359
		P-loop_NTPase	1934..2079	CDD:304359
		P-loop_NTPase	2264..2522	CDD:304359
		P-loop_NTPase	2613..2916	CDD:304359
		MT	2929..3272	CDD:289543
		AAA_9	3304..3519	CDD:289547
		Dynein_heavy	3659..4373	CDD:281078
CG14651	NP_649475.3	DHC_N2	904..>1042	CDD:285579	33/168 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450625
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930