Protein Alignment Dnah3 and DNAH10

DIOPT Version :9

• Sequence 1: NP_647937.2
• Gene: Dnah3 / 38586
• FlyBaseID: FBgn0035581
• Length: 4385
• Species: Drosophila melanogaster
• Sequence 2: NP_001359035.1
• Gene: DNAH10 / 196385
• HGNCID: 2941
• Length: 4589
• Species: Homo sapiens
• Alignment Length: 4863
• Identity: 1406/4863 - (28%)
• Similarity: 2281/4863 - (46%)
• Gaps: 795/4863 - (16%)

  Fly    14 DPRLQDDKLRRK----RTLHLPRVSQAQKKGEKRQLNDCPFYNLT-------YGFDQLPL----- 62
            ||:|.:|.|.|.    ..|.|..::||.::.....|    |...|       ...|::|:
Human    21 DPQLFEDLLNRDDGQGEDLILHFLNQASEEEGPSAL----FIYRTMVPEEVEVEIDEIPVLSEEG 81

  Fly    63 DPVKEFLQEKIS----------HMQTDKIVGHCNREFDFHRYDLDNVKDEYDECDDDSLQELQLE 117
            :..:|...:|:.          .::|:.:....|||           .:|.|:...:.|...:..
Human    82 EEEEETYSQKVESVDKVRAKRVSLRTESLGQPLNRE-----------DEEMDKEISEKLPSKRTA 135

  Fly   118 DIIM------------PEQF------EMLRDAKDHLYNFDSTACNQFPWIDKWMTGVRPSEQEIY 164
            ..||            ||:|      ..||:.|:.:    |.|.:.     |....:.|...|..
Human   136 KHIMEKMHLHMLCTPLPEEFLDQNVVFFLRNTKEAI----SEATDM-----KEAMEIMPETLEYG 191

  Fly   165 EMTSHLLEIYCNRRVRIFYPG-----------CGTSSSLWTNQLRRQHGS-----PSELIGAYRT 213
            .:.:::|....|...::|.|.           .|.:|...:|.  .:|.|     |.|.:..:..
Human   192 IINANVLHFLKNIICQVFLPALSFNQHRTSTTVGVTSGEVSNS--SEHESDLPPMPGEAVEYHSI 254

  Fly   214 PSARHMRVNNMRGPPKKEKFTAGDHYAFRTPQECRNEL---MRV----GKIIDELIEP------- 264
            ...|...:.|:      :||.:...   ||.|:...|:   |.:    |::.|...:|
Human   255 QLIRDEFLMNV------QKFASNIQ---RTMQQLEGEIKLEMPIISVEGEVSDLAADPETVDILE 310

  Fly   265 ---------VLKAAEHKIG-------------------------HGLTKYPDPPSCKDNTNRILR 295
                     :..|.|.::.                         |..||.|......|   .|..
Human   311 QCVINWLNQISTAVEAQLKKTPQGKGPLAEIEFWRERNATLSALHEQTKLPIVRKVLD---VIKE 372

  Fly   296 SAGILVGKKKNCYVGKCRIHRKDFATNEEFLRCLKR--MEATH----------FP-YMQPLQPV- 346
            |..:||...:..:....:.| .:.:.|..||..::|  ...||          .| .|..|:.|
Human   373 SDSMLVANLQPVFTELFKFH-TEASDNVRFLSTVERYFKNITHGSGFHVVLDTIPAMMSALRMVW 436

  Fly   347 ------DPDDQKIKMLAKYRVELA----RAEKLFTLKIQKRYQCLLKSMSIVQLATYPSHLIRKA 401
                  :.|::.|.::.:...|:|    |...|.||..:.|.....|::.    |.....|.:||
Human   437 IISRHYNKDERMIPLMERIAWEIAERVCRVVNLRTLFKENRASAQSKTLE----ARNTLRLWKKA 497

  Fly   402 F--RRINPRSALLQDAYQFIVKEKRDWPKLPPEVILMDYLFVGDRGVRQDLAILIIVCLIDLQED 464
            :  .|....::..:|.::|  ..||.:.:       .||:..    :.|||:.::.:    |:|
Human   498 YFDTRAKIEASGREDRWEF--DRKRLFER-------TDYMAT----ICQDLSDVLQI----LEE- 544

  Fly   465 FRHYVKRSFLNYLLSSNMERRRLQLEREPPEFPILTISPPVSWRSNLLRGKARIGEVL------- 522
                    |.|..               .||...:|..|            .||.:||
Human   545 --------FYNIF---------------GPELKAVTGDP------------KRIDDVLCRVDGLV 574

  Fly   523 -----MTTHPTVQALNRLWHDLYEDLVVVDLGQLLLAQRPLDADTVQVFIEKSCADVR------D 576
                 :|..|.....::.|..:.::..:    ::|:.::     ..:.||::|...:|      |
Human   575 TPMENLTFDPFSIKSSQFWKYVMDEFKI----EVLVIEK-----EAKHFIDESFKTLRSAEAAFD 630

  Fly   577 LLL-------------------NDWLPR-C--ADLMN-------EMRGTWKDLVPMSGKYGGRAA 612
            :||                   ||.|.: |  .|::|       |....:|:..|::|......:
Human   631 MLLKFKHIRSREAVNRQMMMKFNDILAQYCKEIDIINKIFVQNLENPPLYKNHPPVAGAIYWERS 695

  Fly   613 MLFRCIHSAMSRHLNSLISKSINYLFKVLCAFKGGNRIEKY-----------------------S 654
            :.||..|:.:          ....:.::|.:.:|....:||                       .
Human   696 LFFRIKHTIL----------RFQEVQEILDSDRGQEVKQKYLEVGRTMKEYEDRKYEQWMEVTEQ 750

  Fly   655 MFDAKLKRIPLMTLIASVV---------GAHFDHEPINMGPGVRPASNIYVYDEDDADPFQQP-- 708
            :..|.:|: .|:|. :|:.         ||.|   .||..|.:|...|...|.|...  |..|
Human   751 VLPALMKK-SLLTK-SSIATEEPSTLERGAVF---AINFSPALREIINETKYLEQLG--FTVPEL 808

  Fly   709 ------QVNQFVENVPDIDDVAQFELDH----------SNKLYIYPYMQELPRIFTEHFKSI--- 754
                  |.::|:.....|    |..|||          :..:.:..:.|||.|:|...:|.:
Human   809 ARNVALQEDKFLRYTAGI----QRMLDHYHMLIGTLNDAESVLLKDHSQELLRVFRSGYKRLNWN 869

  Fly   755 -LAVG------------YE----------------------IPRLEFVMSGGEPETKGFLHFI-- 782
             |.:|            :|                      |...::..:..|.|..|...|.
Human   870 SLGIGDYITGCKQAIGKFESLVHQIHKNADDISSRLTLIEAINLFKYPAAKSEEELPGVKEFFEH 934

  Fly   783 -------DEDHVD--FL---ELCEKVEQIVKVNWQGVHVYLKPVYKYY----FGLFQKLILPMVQ 831
                   |.||:.  :|   .|..|||.:|.....|....|...|||:    :.:..||||..:|
Human   935 IERERASDVDHMVRWYLAIGPLLTKVEGLVVHTNTGKAPKLASYYKYWEKKIYEVLTKLILKNLQ 999

  Fly   832 K-----------VWTENNL--PEL---GAVQELLKKL-----QAVSDTTYYLR------------ 863
            .           ..||..|  ||:   ....|:.|..     ..|..|.:::|
Human  1000 SFNSLILGNVPLFHTETILTAPEIILHPNTNEIDKMCFHCVRNCVEITKHFVRWMNGSCIECPPQ 1064

  Fly   864 -----DFIPLNLF---MLDNRHVKLSLRMYVREIYDFIIDFYKALN--------WNENRAICEEL 912
                 :.:.:|.:   .|:.:.::.:: |..:.::..:|:..|.|.        |..::||.  :
Human  1065 KGEEEEVVIINFYNDISLNPQIIEQAV-MIPQNVHRILINLMKYLQKWKRYRPLWKLDKAIV--M 1126

  Fly   913 EEMSMKAGERPEETPEVVA----LQNYINDCRE-MRIFAIKDE-------------IKNVLKRVV 959
            |:.:.|       .|..||    ||.|.....| ||...||||             ::...|..|
Human  1127 EKFAAK-------KPPCVAYDEKLQFYSKIAYEVMRHPLIKDEHCIRLQLRHLANTVQENAKSWV 1184

  Fly   960 FLL---------THTYLSSDEL-HLNSRTFILPGELEEVLDLSAARLAVVRD-NLELALRERRME 1013
            ..|         ...|...:|: ||......:|..||: |....|.:|.:|. :|.:.||.|.::
Human  1185 ISLGKLLNESAKEELYNLHEEMEHLAKNLRKIPNTLED-LKFVLATIAEIRSKSLVMELRYRDVQ 1248

  Fly  1014 -------------------------------------FEKLLAQEKRTMDGFRIREIRDV-LTLE 1040
                                                 .|..|...|||.......||.:. :.:|
Human  1249 ERYRTMAMYNLFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIE 1313

  Fly  1041 ELKERVDT-------------VDLLFTTIENLSREAKA---INTEETLLQIDVSAFPLLAEIIEK 1089
            |..:|..:             |:||......|:|..|:   :...|.|..:.::.:|.|.::.::
Human  1314 EFAKRFYSEGPGSVGDDLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKE 1378

  Fly  1090 MEPIEKLWKTSYE------FEKDYLIWMFERFECLNADGVREQVENMHKIMYKLSRQLAYNPV-A 1147
            |..:..:::. ||      .|....:|:     .||...::|.:|...:.:.||.|     || .
Human  1379 MSGLRMIYEL-YEGLKVAKEEWSQTLWI-----NLNVQILQEGIEGFLRALRKLPR-----PVRG 1432

  Fly  1148 KRAAEQMRMKIEKFRVYLPVLDSICRHGLEKRHWDQISKILGRKVN-----PKLFPTLKDMIDVD 1207
            ......:..|::.|:..:|:|..:....|..|||    |.|..|.:     .:.| ||::|..::
Human  1433 LSVTYYLEAKMKAFKDSIPLLLDLKNEALRDRHW----KELMEKTSVFFEMTETF-TLENMFAME 1492

  Fly  1208 IMSILPQLEEIANAAGKEYDLNNGLRIMQADWRDVMFEVLQY---RDSDTHILASLDDIQTLLDD 1269
            :......|.||..||.||..:...::.:...|.::.|.|::|   .....:||.|:|:|...|||
Human  1493 LHKHTDVLNEIVTAAIKEVAIEKAVKEILDTWENMKFTVVKYCKGTQERGYILGSVDEIIQSLDD 1557

  Fly  1270 HIMRTQAMKRSPFITALGSKADDWEARLLLIQNIIDAWTQVQITWMYLEPIFSSEDIMRQMPLEG 1334
            :....|::..|.|:.........||..|.||..:|:.|..||..|||||.||...||..|:|.|.
Human  1558 NTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGGDIRSQLPEEA 1622

  Fly  1335 RNFKAVDKLWRKIMKHTLKDRHVMAATEYPEMLEVFTKAIEDLETVTKGLNTYLEQKRLFFARFF 1399
            :.|..:||::::||..||||..:....|.|..|.......|.||...|.||.||:.||..|.|||
Human  1623 KKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFF 1687

  Fly  1400 FLSNDELLEILSETKDPMRVQPHLRKCFEGIGSLTFDD---NMEIVEMVSDEEERVALVRKINPQ 1461
            |:|:||||.||. :.||:.||.|:.|.::.|.||.|:|   ..::|..:...|..|...|||  .
Human  1688 FISDDELLSILG-SSDPLCVQEHMIKMYDNIASLRFNDGDSGEKLVSAMISAEGEVMEFRKI--L 1749

  Fly  1462 LANGLVEMWLKEV--EMVMLDSV--KEQMREAWEDYAMVERISWVVSWPGQVVQGISCMAWTYEV 1522
            .|.|.||.|:..|  ||...:.:  ||.:....||.:   |:.|::.:.|.||...|.:.||:||
Human  1750 RAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRS---RVDWMLLYQGMVVLAASQVWWTWEV 1811

  Fly  1523 EEAI------ETKELPAYLEKSNLQIADLVQLVRTDLQAGVRIAVEALIVLDVHDRDVVKYLTDC 1581
            |:..      |.:.:..|..|.:.||.:||..:...|....|.....::::|||.||:|......
Human  1812 EDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVLIIDVHARDIVDSFIRG 1876

  Fly  1582 RITNIQDFDWISQLRYYWKVNEKNEDWVCVSMVVTDVEYGMEYLGNLPRLVVTPLTDRCYRTLMG 1646
            .|...::|||.||||:||   ::..|.:.:........||.||:|...|||:||||||.|.||..
Human  1877 SILEAREFDWESQLRFYW---DREPDELNIRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLTQ 1938

  Fly  1647 ALKLCLGGAPEGPAGTGKTETCKDLAKAVAKKCVVFNCSDGLDYKALGKFFKGLAQSGAWACFDE 1711
            ||.:.|||||.||||||||||.||||||:...|||.||.:|:||:|:||.|.||||.|||.||||
Human  1939 ALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDE 2003

  Fly  1712 FNRIELEVLSVVAQQILTIQRAIGRKVVKFFFEDTMLKLDPTCSIFITMNPGYAGRTELPDNLKV 1776
            ||||:..||||::.||.||:.|:..::..|.||...:.||....||||||||||||||||:::|.
Human  2004 FNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKA 2068

  Fly  1777 LFRTVAMMVPDYAMIGEITLYSNGFDMARNLSQKIVQAYKLCSEQLSSQSHYDYGMRAVKSVLLA 1841
            |||.|.::|||...|.||.|:|.||..|:.|::|:...|||..||||.|.|||:|:||:||||:.
Human  2069 LFRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVM 2133

  Fly  1842 SASLRRLYVDLPEPEIVLRAIVDVNLPKFLEQDISLFIGIYMDLFPGVELPMPQRGDILKWLHIN 1906
            :..|:|...||.|..:::||:.|:|||||:.:|:.||:|:..|||||::.|..:..|....:...
Human  2134 AGELKRGSSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQV 2198

  Fly  1907 LADRNLQATPWYLEKILQIYEMLLVRHGLMIVGGSMGGKTTAYQVLAQTLRNVSTDEEATLKEFP 1971
            |.:......|..::|::|::|.:|.||..|:||.:.|||:    |:..||....|....|.|.:
Human  2199 LEENGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGKS----VVINTLCQAQTKLGLTTKLY- 2258

  Fly  1972 VTFRIINPKAITMGQLYGRFDPVSHEWYDGVLAKTFREQVQGP--KGERAWVMFDGPVDAVWIEN 2034
                |:||||:::.:|||..||.:.:|.||||:..||| :..|  |.||.:::|||.|||:|:||
Human  2259 ----ILNPKAVSVIELYGILDPTTRDWTDGVLSNIFRE-INKPTDKKERKYILFDGDVDALWVEN 2318

  Fly  2035 LNTVLDDNKKLCLMSGEIMQMTKLMNMMFEPADLEQASPATVSRCGMIYMEPSQLGWRALHKSFI 2099
            :|:|:|||:.|.|.:||.:::.....::||..||:.|||||||||||:|::|..|.:|...|.::
Human  2319 MNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWV 2383

  Fly  2100 NVLVNKVGLGDIYMTLFEDMTEWLVPAALEFLPQCKQMLELSPIYQYQTFSRFFLHFLEKHKQFN 2164
            |.:.|||...:: .:|||....:|:...:|.:...:|..:|..|.. ||.........:......
Human  2384 NQIPNKVEQYNL-NSLFEKYVPYLMDVIVEGIVDGRQAEKLKTIVP-QTDLNMVTQLAKMLDALL 2446

  Fly  2165 QAWFQQM-FLFCF--AWAYCS---ALTGQGQKTFDALLRKVIYGSNENFPKPKYFSLNRGQMFPE 2223
            :...:.: .|.|:  ...|||   :|...|:..||..::::...|..:   .:....|.|::..:
Human  2447 EGEIEDLDLLECYFLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVD---TEGVWANPGELPGQ 2508

  Fly  2224 KLLFLDYRFDEAENWWT-WQKSDDSASTTSNFPENAQISELIVPTKETGYISYWQEFCISKSYAM 2287
            .....|:.||...|.|. |.|   ......:.||...|: ::|.|.:|...::..|..:.....:
Human  2509 LPTLYDFHFDNKRNQWVPWSK---LVPEYIHAPERKFIN-ILVHTVDTTRTTWILEQMVKIKQPV 2569

  Fly  2288 LVVGPTGTGKSAIITSNLLAMPKFANLVNVINFSARTSAQMVQDTIMSKLDRRRKGVFGPSLGKK 2352
            :.||.:||.|:|...:.|..:.:..|:|.::|||:||::..:|..:.:.:::|.|..:||.:||:
Human  2570 IFVGESGTSKTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKR 2634

  Fly  2353 CTVFCDDVAMPSKDTYGSQAPLELLRTWLDHGYWSDLVDTTKIELV-DMTLMCAMGTLGGS-NFI 2415
            ..||.||:.||..|.||:|.|:.||:..|:.||..|.......:.: |:..:.|||..||. |.:
Human  2635 LLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGGRNEV 2699

  Fly  2416 FPRLYRHMFVVAVDSFEDSTIVRIFTTIGDWHFSKGYPEKVALLSRGLSEAMVSVYRDAIRSFLP 2480
            .||......|..|....:.::..|:::|...|.|. :.|.:..:|..|:...:::|::.::...|
Human  2700 DPRFISLFSVFNVPFPSEESLHLIYSSILKGHTST-FHESIVAVSGKLTFCTLALYKNIVQDLPP 2763

  Fly  2481 TPAKSHYSFSLRDITRVFQGIVMVPPKRMPDPEKLGRLWAHETYRVFYDRLVDQQDRDRLLV--- 2542
            ||:|.||.|:|||::|||.|:|:..|:|.....::.|:|.:|..|||:|||:.:.|:.  ||
Human  2764 TPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRLISETDKQ--LVQQH 2826

  Fly  2543 ---MAVDACKSNLRFPLEQAFGERIEPGEKLTDNDLRNLFYGNYMEP--DAEPKFYDEGDTYEKL 2602
               :.|:..|.::...:.       :|           :.:|::...  :.||:.|::...||..
Human  2827 IGSLVVEHFKDDVEVVMR-------DP-----------ILFGDFQMALHEGEPRIYEDIQDYEAA 2873

  Fly  2603 EKLMKYYLREYNSFSSTPMDLVMFRFAIEHVSRVSRVLQMPRGNILMVGMGGSGRRSSARLAAYI 2667
            :.|.:..|.|||. |:|.|:||:|..|:||::||.|:::|.||:.|:||:||||::|.:||||:.
Human  2874 KALFQEILEEYNE-SNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQSLSRLAAFT 2937

  Fly  2668 ADCRLMTVQVSKSYTITDWRDDLKKILMSASFNLNHTVFLFSDAQATDEGYVEDINGILNTGDLP 2732
            |.|.:..:.:|:.|:...:|:|||.:.:.........:|||:||...:||::|.||.:|.:|.:|
Human  2938 ASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGFLELINNMLTSGIVP 3002

  Fly  2733 NLYQLEDKATIMENMANVAKQLGKILDTLPSEVYAYYIDRIREQLHIALAFSPIGDSFKERIRVY 2797
            .|:..|:|.:|:..:...|.:.|  :......|:.|::::....|||.|..||:||:.:...|.:
Human  3003 ALFSEEEKESILSQIGQEALKQG--MGPAKESVWQYFVNKSANNLHIVLGMSPVGDTLRTWCRNF 3065

  Fly  2798 PSLINCCTIDWYMPWPEEALSRVGVYFVSSMNLNRPHGEETQEPVQSKDAADPDEEEVRRETVGV 2862
            |.::|...|||:||||.:||..|...|:         |.....|.::.:
Human  3066 PGMVNNTGIDWFMPWPPQALHAVAKSFL---------GYNPMIPAENIE---------------- 3105

  Fly  2863 EREQTQLEADLVDCVMYFHQSVVDASEKCYLELNRRNYVTPSAYLELLKAFRTFYTRKLDEITRL 2927
                     ::|..|:..||||...|::...:|.|.|||||..||:.:..    |::.|||.|:.
Human  3106 ---------NVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINT----YSKLLDEKTQC 3157

  Fly  2928 R----DRYTTGLEKLDFAAGQVGEMQTNLYDLQPKLKVLSEETDRIMVNIERETAEAEKKKEVVG 2988
            .    .|...||:||..|..|:.|:...|.:.:..|...|...:.::..|...||.||:||::
Human  3158 NIAQCKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKL-- 3220

  Fly  2989 ADEAA-----ANEAAAAAQAIKDDCETDLAEAIPAMEAALEALNTLKPADIFIVKSMKNPPYGVK 3048
            |:|.|     .|:..|..:|   :.||.|||.:|.:|||...|..|..:|:..::|...||..|:
Human  3221 AEEKAMEIEEQNKVIAMEKA---EAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQ 3282

  Fly  3049 LTMEAVCVIRGIKPDRKPDPSGHMVEDYWGPSMRMLSDMKFLDSLKTFDKDNIPPPIIKRIREKY 3113
            ...|.:.:::|.|            |..|..:..::||..||.||...|.|:|....:|.|: ..
Human  3283 TVCECILIMKGYK------------ELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIK-GL 3334

  Fly  3114 IADRDFVPEKIKAASMACEGICRWVRAMDVYDKVARIVMPKKAALAEAEGELSQQMEKLNAKRAE 3178
            :...:...|:::|.|.|..|:.::|.|:..|..|.|.:.||:..:|..|........:|...:.|
Human  3335 LKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNE 3399

  Fly  3179 LQVILDKLQKLNDFFAEKSREKKRLEDEIDNCEKKLNRAEKLLGGLGGEKTRWSEAAKNLHESIS 3243
            |..|..:|:.|...:.....||::|::|.:..|::|..|:||:.|||.|..||......|.....
Human  3400 LAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRV 3464

  Fly  3244 NIVGDVLLAGGCTAYLGYFTTEYRVNILDD-WNALCKRKHIPSSETFSLATTLGHPMTIRAWSLA 3307
            .::||.||.....:|.|.||.|:|..:::. |......:.||.|:.|.|.:.|...:.|..|...
Human  3465 KLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDDVEISRWGSQ 3529

  Fly  3308 GLPADNFSVENGIIVTNSSRYSLLIDPQVQANKWIKNMEKNNNLKVIKQSDANYMQVLELAITFG 3372
            |||.|..||:|||:.|.:||:.|.||||.||..|||..|:.|||:|...:|.::::.||::|.:|
Human  3530 GLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYG 3594

  Fly  3373 QPVLIENVGEKLDSNLTPILEKNVIKHKGGLFIKSGDQMIEYNPNFRLYITTCLRNPRYPPEVMV 3437
            .|.|..:|.|.:|..:..:||||:...:|..||..||:.::|:.|||||:.|.|.||||.|.|..
Human  3595 TPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVFG 3659

  Fly  3438 MVTVLNFMITEQGLREQLLAIVVAHERPDLQEKKEQLIIESARNRDALYTIESKILEVLSTSEGN 3502
            ...|:|:.:|.:||.:|||:::||:||.:|:|::|.||.|::.|::.|..:|..:|..|:||.||
Human  3660 KAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGN 3724

  Fly  3503 VLEDENAINILSSSKILSEDIQEKQVIAVATEIEIDAARQQYIPVSKHSAILFFCISELANVDPM 3567
            :|::.:.::.|..:|..:.::.||..:|..|.::||..|..|.|.::..|||||.:||:|.|:.|
Human  3725 MLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSM 3789

  Fly  3568 YQYSLSWFLNLFVNTILKAPKSDQLSERLKNLNDYFTKSIYTNVCRSLFEKDKLVISLVMCLGIL 3632
            |||||..||.:|..::.|:.....|.:||:|:.|..|.|||.:.|..|||:.||:.|..|.:.|.
Human  3790 YQYSLIAFLEVFRLSLKKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIE 3854

  Fly  3633 VSQGRVEKAALLFFLTGGIGYKTIPPNPLGAWLPDKSWASVCKAADL--EGLKNLPQMMETYSDE 3695
            .::|||.:..|.|||.|.|..:........|||.|:.|..:...:::  :....||..:|.....
Human  3855 QAEGRVPQEELDFFLKGNISLEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTV 3919

  Fly  3696 WHNFYDASNPDQLQLPAPH-NTVNDMYFLIVIKSLRPDKLVPAVRAFITRNLDRSFVEPPPFDLA 3759
            |..:||..:.:|..:|..: |.:.....|::::..|.|::..||..::|..:...:|:||.....
Human  3920 WQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFE 3984

  Fly  3760 ASFADSSPKIPLVFLLSAGSDPMASLFMFAKQRNM-YDKLKTISLGQGQGPRAEKMIMEAARHGQ 3823
            |.|..|:|..|:||:||.||||...|...|::... .::||.:::||||...|.:::..|...||
Human  3985 AIFEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQEKVALQLLETAVARGQ 4049

  Fly  3824 WVVLQNCHVAISWMGDLERICNDTTLTDGANHDYRLWCTSYPSAVFPVSVLQNSVKMTNEPPKGL 3888
            |::|||||:.:.|:.|||:.....|   ..:.|:|||.|:.|:..||:.:||.|:|:..|||.||
Human  4050 WLMLQNCHLLVKWLKDLEKSLERIT---KPHPDFRLWLTTDPTKGFPIGILQKSLKVVTEPPNGL 4111

  Fly  3889 RANMHRSFTSDPLMRDKFFTNAFLFSDSANKCWLRGVFALVFFHAVVQERREFGPLGWNIPYEFN 3953
            :.||..::         |..:..:.....:..:...|:.|.||||||||||:||.:|||:.|:||
Human  4112 KLNMRATY---------FKISHEMLDQCPHPAFKPLVYVLAFFHAVVQERRKFGKIGWNVYYDFN 4167

  Fly  3954 ESDLKISLLQL-----KMFINQSQSIPFRGHVYLTGECNYGGRVTDDKDRRLILSLL-----NMI 4008
            |||.::.:..|     |.|..:...||:....||.||..||||..|..|||::...:     :.|
Human  4168 ESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFI 4232

  Fly  4009 YNPNTIEEDNYALSQSGTYRVPLSPTRLNSIEYVSSFPLSPHPEVYGLHENADINRNVKETNALI 4073
            :  :|.:..::..::...|::|:...:...:|.:.:.||:..|||:|||.||:|....:....:.
Human  4233 F--DTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGLHPNAEIGYYTQAARDMW 4295

  Fly  4074 SGVLLTQTDLMASVKASSSGGAKEDPAIAICKQVLKQLPEEFNIDEVSKTYPVIYTNSMNTVLRQ 4138
            :.:|    :|......||||.:::|....:.|::..::|:.|::|:|.|.... ..:..:.||.|
Human  4296 AHLL----ELQPQTGESSSGISRDDYIGQVAKEIENKMPKVFDLDQVRKRLGT-GLSPTSVVLLQ 4355

  Fly  4139 ELIRFNRLLSYIRKSLVNVGKAVVGQIAMIPELERTHASMVIGKLPADWLKKSYPSLKPLGSYVS 4203
            ||.|||:|:..:.|||..:.:|:.|::.|..||:....|:.||.:|..|.:.:..:||.||:::.
Human  4356 ELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSLFIGHIPNIWRRLAPDTLKSLGNWMV 4420

  Fly  4204 DLLARLAFFQEWIDNGEPMVYWISGFYFTQSFITGVLQNYSRKNRFQIDMILIEFAVTKFE--VQ 4266
            ..|.|.:.:..|:...||.|.|:||.:..:|::|.::|...|||.:.:|...:...||||:  .:
Human  4421 YFLRRFSQYMLWVTESEPSVMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLFTQVTKFQDADE 4485

  Fly  4267 VPGTPDIGAYIRGIFIEGARWNRKTKEVDESFSKVLFDTLPVIYLRPV----LKALEDLPRSTAG 4327
            |......|.::.|:::|||.|:.:...:.:|..|||...||::.:.|:    ||.
Human  4486 VNERAGQGCFVSGLYLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAHRLKL---------- 4540

  Fly  4328 GEPETIYDCPVYKTSERRGVLSTTGHSTNFVMYLQLRCSRKPMHWINRGTACL 4380
               :..:..|||.||.||..:     ....|....|..:|...||:.:| .||
Human  4541 ---QNTFRTPVYTTSMRRNAM-----GVGLVFEADLFTTRHISHWVLQG-VCL 4584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dnah3	NP_647937.2	DHC_N2	1086..1489	CDD:285579	133/424 (31%)
		P-loop_NTPase	1620..1847	CDD:304359	134/226 (59%)
		P-loop_NTPase	1934..2079	CDD:304359	63/146 (43%)
		P-loop_NTPase	2264..2522	CDD:304359	80/259 (31%)
		P-loop_NTPase	2613..2916	CDD:304359	98/302 (32%)
		MT	2929..3272	CDD:289543	102/347 (29%)
		AAA_9	3304..3519	CDD:289547	91/214 (43%)
		Dynein_heavy	3659..4373	CDD:281078	221/733 (30%)
DNAH10	NP_001359035.1	DHC_N1	306..876	CDD:369845	118/660 (18%)
		DYN1	1274..4265	CDD:227570	1050/3128 (34%)
		DHC_N2	1372..1777	CDD:369852	133/423 (31%)
		AAA_6	1912..2238	CDD:372306	170/325 (52%)
		AAA_8	2891..3150	CDD:372310	95/298 (32%)
		Dynein_C	4288..4586	CDD:375627	90/321 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810