DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32237 and CG11131

DIOPT Version :9

Sequence 1:	NP_729037.1	Gene:	CG32237 / 38584	FlyBaseID:	FBgn0052237	Length:	911	Species:	Drosophila melanogaster
Sequence 2:	NP_001262228.1	Gene:	CG11131 / 40511	FlyBaseID:	FBgn0037204	Length:	229	Species:	Drosophila melanogaster

Alignment Length:	307	Identity:	123/307 - (40%)
Similarity:	155/307 - (50%)	Gaps:	90/307 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLFLA----CIFIAAATAAVIPVEQARHRRDVSEIVNEYIPPAEEVGAELAQDPAALGDDGYRY 61
            ||||.|    |:...||..:..|..       ..|..:||:||..|  ||.||    |.::||:|
  Fly     1 MKLFTAVLAICLVAFAAAQSADPAA-------ALEPSSEYLPPVGE--AEAAQ----LSENGYKY 52

  Fly    62 KTVRRLKLRQRRDVSEIANEYLPPTEEVVADAPVEEV--PVEEASQDSAVLAADGYQYKTVRRLK 124
            :||||||||.||:|..  .|||||.|    :||.:|.  ||:.|:.....:|.|||:|||||:||
  Fly    53 RTVRRLKLRHRREVPN--QEYLPPVE----NAPSQEYLPPVDAAAIGDTKVADDGYRYKTVRKLK 111

  Fly   125 Y--RQRRDVSDIA---NEYLPPTEEVVADAPVEEVPVEEASQDSAVLAADGYKYKTVRRLKYRQR 184
            :  |.|||||:||   .|||||            |.||.|.:...:|..||||||||||||:|:.
  Fly   112 FRARHRRDVSEIAEPSGEYLPP------------VQVELAPELKTILGDDGYKYKTVRRLKFRRH 164

  Fly   185 RDVSEIANEYLPPTEEVVADTPVEEVPVEEASQDSAVLAADGYKYKTVRRLKYRQRRDVSEIANE 249
            |             .|.||         |||:.:|   |.:|                      |
  Fly   165 R-------------REAVA---------EEAAAES---APNG----------------------E 182

  Fly   250 YLPPTEDAATEAPIEEAPVEEASQDSAVLAADGYQYKTVRRLKYRQR 296
            ||||.| ||..||.......:::::...||.|||:|||||||:||.|
  Fly   183 YLPPAE-AAAAAPAAAEAEPKSAEEGTELAKDGYRYKTVRRLRYRYR 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32237	NP_729037.1	GYR	56..73	CDD:128953	11/16 (69%)
		GYR	168..185	CDD:128953	13/16 (81%)
		GYR	224..241	CDD:128953	1/16 (6%)
		GYR	336..353	CDD:128953
		GYR	448..465	CDD:128953
		GYR	616..633	CDD:128953
		GYR	728..745	CDD:128953
		GYR	892..909	CDD:128953
CG11131	NP_001262228.1	GYR	99..116	CDD:111632	10/16 (63%)
CG11131	NP_001262228.1	GYR	212..229	CDD:111632	13/17 (76%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450157
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008548
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840