Protein Alignment CG13708 and Lrrc56

DIOPT Version :10

• Sequence 1: NP_647933.1
• Gene: CG13708 / 38582
• FlyBaseID: FBgn0035577
• Length: 1301
• Species: Drosophila melanogaster
• Sequence 2: XP_006536303.1
• Gene: Lrrc56 / 70552
• MGIID: 1917802
• Length: 559
• Species: Mus musculus
• Alignment Length: 612
• Identity: 124/612 - (20%)
• Similarity: 203/612 - (33%)
• Gaps: 189/612 - (30%)

  Fly   405 PGGAASNLLQSCDEG-SALHNSNLSLYGGCG--------EEEESPSVMTSISALEQLS------- 453
            ||.|:..:.:...:| :..|..|..| |..|        ||..||:.:.:::.::.|.
Mouse    20 PGTASIRVRELSWQGLNNPHPQNKRL-GSHGDIHRERWVEERLSPARLQALAQVDDLQLVRVLEM 83

  Fly   454 -IKNKQLSLSASYGSIFQQLVFLDLYDNQIERIANL-DGLPSLSVLLLGKNRITDIGGLSSLKDT 516
             :..::.|| .::|.....|:.|.|..:.:..:.:| ..|..|.||.|.:..:||:.|:.|..:
Mouse    84 CVDTRKNSL-GNFGLYLPNLIQLKLNHSYLGSLRDLGTSLGHLQVLWLARCGLTDLDGIGSFLE- 146

  Fly   517 LRVLDLHGNKLTSLGSRINCLQQLKSLNLAGNQIRQINQQDFLGLRC--LRELNLKRNKL----- 574
            |:.|.:..|.::.| |.:..|:||:.|:|.||.:..:.|..:|.| |  |..|.|:.|.:
Mouse   147 LKELYVSYNNISDL-SPLCLLEQLEVLDLEGNNVEDLGQMRYLQL-CPRLAMLTLEGNLVCLKPD 209

  Fly   575 -----RRINGFQHLVALERL--------------------------WLCHND-----------LH 597
                 :...|:.:...:::|                          ||...:           |.
Mouse   210 PGPSNKAPQGYNYRAEVKKLIPQLHVLDEVPTTCTSAPAPQTLSQDWLMVKEAIKEGSVLDILLP 274

  Fly   598 RVDDM--ASIARATRLLEVTIENNPVSLAGDCVSFLVSYLPLLQ-TLSQMPITEQVRRAALAWRQ 659
            |:||.  |:|.:....|.|. |..|.:|     |.||...||.: .||:.|.||          .
Mouse   275 RLDDPHGATIRKFDPTLPVP-ETQPWAL-----SLLVPGGPLPEGLLSENPATE----------D 323

  Fly   660 HKEQAQAAPGSSEAYHNIRREEVISNARTNWELLRSQQTVVGRPKSRLTSELAKINESNEGPAGE 724
            |.......||                           |.:.|.|...|
Mouse   324 HASNLTHGPG---------------------------QVLCGNPTKGL----------------- 344

  Fly   725 EGEMESEESQQPKELMDELQALIKLPPIAKDL----RNPHEEDGASSEASSLG------PNVDSC 779
                     ::.:....|...|.::||...||    ..|..:...|.:.:..|      |.:...
Mouse   345 ---------RKRRNQYQEWAPLEQMPPHRPDLAIRPSTPRPDPAESCDLAMTGLRAWTEPGLRPL 400

  Fly   780 SSCYSSDNEDGGAKNKPQTPQIDENSNKVGLTEKPPSSPVTVASQSPEVAIVTPSAPVSSSPSPP 844
            ........::..|:.:.|.||.|               ||....|:.....:||...||......
Mouse   401 LQRQLEFQQERSAQVQAQDPQKD---------------PVEQEDQTGPKTSLTPPRLVSELSRTS 450

  Fly   845 ALTLTPPAAPGTPVPGTTSPSPSTTIISTLPVPATASSNASRPTSSKQRSRHAPITQLGLQINQR 909
            ...|. |:.|..|:|                 |.:..|:..|......|.|...:  ||......
Mouse   451 GFHLI-PSPPKYPMP-----------------PESGISSLGRSADLPFRGRRLRV--LGSLGPSL 495

  Fly   910 GGAAASSKRYMAGSLVRAQTVSSSTSN 936
            |..:...:|..|.:.:||...||..|:
Mouse   496 GEGSVLGERLAAVTALRALEASSGPSH 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13708	NP_647933.1	leucine-rich repeat	449..471	CDD:275380	4/29 (14%)
		PPP1R42	467..661	CDD:455733	58/246 (24%)
		leucine-rich repeat	472..493	CDD:275380	5/21 (24%)
		leucine-rich repeat	494..516	CDD:275380	8/21 (38%)
		leucine-rich repeat	517..539	CDD:275380	6/21 (29%)
		leucine-rich repeat	540..563	CDD:275380	8/22 (36%)
		leucine-rich repeat	564..585	CDD:275380	5/30 (17%)
		leucine-rich repeat	611..637	CDD:275380	8/25 (32%)
Lrrc56	XP_006536303.1	LRR	<90..>203	CDD:443914	35/116 (30%)
		leucine-rich repeat	102..124	CDD:275380	5/21 (24%)
		leucine-rich repeat	125..146	CDD:275380	8/20 (40%)
		leucine-rich repeat	147..168	CDD:275380	6/21 (29%)
		leucine-rich repeat	169..193	CDD:275380	9/24 (38%)