DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13708 and CG8800

DIOPT Version :9

Sequence 1:	NP_001261433.1	Gene:	CG13708 / 38582	FlyBaseID:	FBgn0035577	Length:	1301	Species:	Drosophila melanogaster
Sequence 2:	NP_610483.1	Gene:	CG8800 / 35962	FlyBaseID:	FBgn0033408	Length:	188	Species:	Drosophila melanogaster

Alignment Length:	230	Identity:	53/230 - (23%)
Similarity:	88/230 - (38%)	Gaps:	75/230 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   441 SVMTSI-SALEQLSIKNKQLSLSASYGSI-FQ---------------QLVFLDLYDNQIERIANL 488
            |..|:| .||::...:.:|.||:|....: ||               |...:.:..|.||:|..|
  Fly     2 SKATTIKEALKRWEEREQQNSLTAKVIDLQFQWPPIEKMDSTLGTLVQCERISMSTNMIEKIFGL 66

  Fly   489 DGLPSLSVLLLGKNRITDIGGLSSLKDTLRVLDLHGNKLTSLGSRINCLQQLKSLNLAGNQIRQI 553
            .|:..|.||.|.:|.|..|.||.::.:||..|.|          ..|.::::|.|.
  Fly    67 SGMKCLKVLSLSRNYIKQISGLEAVAETLEELWL----------SYNLIEKIKGLT--------- 112

  Fly   554 NQQDFLGLRCLRELNLKRNKLRRINGFQHLVALERLWLCHNDLHRVDDMASIARATRLLEVTIEN 618
                  ||:||:.|.:..|.::..:.|..|..:|.|          :|:            .:..
  Fly   113 ------GLKCLKVLYISNNLIKDWSEFNRLAEIESL----------EDL------------VVVG 149

  Fly   619 NPVS-------LAGDCVSFLVSYLPLLQTLSQMPI 646
            ||:|       ...:|    :..||.::.|...|:
  Fly   150 NPLSEGLDEPTWRAEC----IKRLPTIRKLDGEPV 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13708	NP_001261433.1	LRR_RI	<428..572	CDD:238064	39/147 (27%)
		leucine-rich repeat	449..471	CDD:275380	7/37 (19%)
		leucine-rich repeat	472..493	CDD:275380	6/20 (30%)
		LRR_8	475..527	CDD:290566	19/51 (37%)
		leucine-rich repeat	494..516	CDD:275380	9/21 (43%)
		LRR_8	516..574	CDD:290566	13/57 (23%)
		leucine-rich repeat	517..539	CDD:275380	4/21 (19%)
		leucine-rich repeat	540..563	CDD:275380	4/22 (18%)
		LRR_4	564..604	CDD:289563	8/39 (21%)
		leucine-rich repeat	564..585	CDD:275380	5/20 (25%)
		leucine-rich repeat	611..637	CDD:275380	5/32 (16%)
		LRR_9	<1059..1153	CDD:258718
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	41/193 (21%)
		leucine-rich repeat	50..71	CDD:275380	6/20 (30%)
		leucine-rich repeat	95..116	CDD:275380	8/45 (18%)
		leucine-rich repeat	117..141	CDD:275380	5/23 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810