Protein Alignment CG13708 and Lrrc43

DIOPT Version :10

• Sequence 1: NP_647933.1
• Gene: CG13708 / 38582
• FlyBaseID: FBgn0035577
• Length: 1301
• Species: Drosophila melanogaster
• Sequence 2: NP_001163867.1
• Gene: Lrrc43 / 288751
• RGDID: 1561461
• Length: 681
• Species: Rattus norvegicus
• Alignment Length: 661
• Identity: 141/661 - (21%)
• Similarity: 221/661 - (33%)
• Gaps: 199/661 - (30%)

  Fly   434 GEEEE-------------SPSVMTSISA-----LEQLSIKNKQLSLSASYGSIFQQLVFLD---- 476
            |.|||             ||..|...|:     |.:|:|:|........:.|.|:.|..:|
  Rat    71 GPEEETVEALLGLVRSSHSPWAMLKDSSAEDRFLRELAIQNPLTIKDTFFYSYFRCLRVVDKGVS 135

  Fly   477 LYDNQIERIANLDGLPSLSVLLLGKNRITDIGGLSSLKDTLRVLDLHGNKLTSLGSRINCLQQLK 541
            |.|.:|.:...|:      .|:|..|:|.||.. ::|..||:||:|:||.:.|:    .||....
  Rat   136 LVDKEILKFLKLE------ELVLSANKIKDIDA-NNLPPTLKVLELYGNLIASM----ECLCSPP 189

  Fly   542 SLNLAGNQIRQINQQDFLGLRCLRELNLKRNKLR--------RINGFQHLVALERLWLCHNDLHR 598
            ..|                   |:.|.|..|||.        ..|.:..||:|:   |..|||..
  Rat   190 PPN-------------------LQHLGLGHNKLLGPLESLYVTSNNWPLLVSLD---LGFNDLTD 232

  Fly   599 VDDM---ASIARATRLLEVTIENNPVSLAGDCVSFLVSYLPLLQTLSQMPITEQVRRAALAWRQH 660
            :..|   .|..:..|||  .::.||::|......|.|..|..|..|..:.::...:........|
  Rat   233 LQSMILGLSTLKCLRLL--VLQGNPLALVPYYRGFTVDSLARLCVLDDITVSPSEKHQFRGLNSH 295

  Fly   661 KEQAQAAPGSSEAYHNIRREEVISNARTNWELLRSQQTVV--GRPKSRLTSELAKINESNEGP-- 721
            .:.                            |.|..|.||  |..:..|.|.:.......:||
  Rat   296 GDL----------------------------LAREAQFVVTIGNVRGVLDSSILDPEPGPDGPFI 332

  Fly   722 -------------AGEEGEMESEESQQPKELMDELQALIKLPPIAKDLRNPHEEDGASSEASSLG 773
                         ..:||.....|...|..::||    |..|....|.....||:........|
  Rat   333 SYSYYVTYDFVEDEEKEGITSGMEELHPDSVLDE----IDKPSSGMDEEEEEEEEEEEDRQEVL- 392

  Fly   774 PNVDSCSSCYSSDNEDGGAKNKPQTP----------------QIDENSNKVGLTEKPPSS----- 817
             :|....:.:....:.|..:.:|::|                |:.|:|.:.|:||...|.
  Rat   393 -SVFQSQAHHRPVRQGGRHRFRPESPEVMSRELSEYIVKEMNQMAEDSGESGITEVDESETSISI 456

  Fly   818 -----PVTVASQSPEVAIVTPSAPVSSSPSPPAL---TLTPPAAPGTP----------------- 857
                 |.::.| |.|:|.:.|...|...|||..:   |:..|.|...|
  Rat   457 HSAPLPQSIDS-SEELAKLRPRLDVRLCPSPGTVLFSTMHKPWADVIPCTYEMKHTLKELIRVKA 520

  Fly   858 --VPGTTSPSPSTTIIS--TLPVPATASSNASRPTSSKQ-----------RSRHAPITQLG---- 903
              :.|||.......|||  .:|.|..:...|.:....|:           |.:..|..:|.
  Rat   521 FLLSGTTVSIVEEKIISWPVVPTPVESPLPAKKGKGDKKKKEEPAKDKGPRKKKEPPRELRQDPP 585

  Fly   904 -LQINQRGGAAASSKRYMAGSLVRAQTVSSSTSNSSSSNSAGRGKATNNGLNLVATQTKAATSGN 967
             |::      ..|.:.|:. .|:..:.|.|:..|...:.:....:.|      .|..:|....|:
  Rat   586 VLRV------LGSGQVYLE-PLLAGEPVVSTVCNFGVARTLETDRLT------YARDSKKVKKGS 637

  Fly   968 NQSSAGAAAGT 978
            .:..:.|||.|
  Rat   638 KKDKSKAAAPT 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13708	NP_647933.1	leucine-rich repeat	449..471	CDD:275380	6/21 (29%)
		PPP1R42	467..661	CDD:455733	53/208 (25%)
		leucine-rich repeat	472..493	CDD:275380	6/24 (25%)
		leucine-rich repeat	494..516	CDD:275380	7/21 (33%)
		leucine-rich repeat	517..539	CDD:275380	9/21 (43%)
		leucine-rich repeat	540..563	CDD:275380	1/22 (5%)
		leucine-rich repeat	564..585	CDD:275380	8/28 (29%)
		leucine-rich repeat	611..637	CDD:275380	8/25 (32%)
Lrrc43	NP_001163867.1	leucine-rich repeat	147..168	CDD:275378	8/27 (30%)
		PPP1R42	150..289	CDD:455733	45/167 (27%)
		leucine-rich repeat	169..192	CDD:275378	9/26 (35%)
		leucine-rich repeat	193..219	CDD:275378	7/25 (28%)
		leucine-rich repeat	220..245	CDD:275378	9/27 (33%)