Protein Alignment CG13708 and Lrrc23

DIOPT Version :10

• Sequence 1: NP_647933.1
• Gene: CG13708 / 38582
• FlyBaseID: FBgn0035577
• Length: 1301
• Species: Drosophila melanogaster
• Sequence 2: XP_006505721.1
• Gene: Lrrc23 / 16977
• MGIID: 1315192
• Length: 370
• Species: Mus musculus
• Alignment Length: 364
• Identity: 83/364 - (22%)
• Similarity: 138/364 - (37%)
• Gaps: 108/364 - (29%)

  Fly   436 EEESPSVMTSISALEQLSIKNKQLSLSASYGS-IFQQLVFLDLYDNQIERIANLDGLPSLSVLLL 499
            ||..|:.:|.       ::..:.|||....|| :....:.|:..|..:..|:.|.....|..:.:
Mouse    68 EEWLPTPITE-------AMMKEGLSLLCKIGSGLAHAYIKLEAKDRDLTDISLLRSYIHLRYVDI 125

  Fly   500 GKNRITDIGGLSSLKDTLRVLDLHGNKLTSLGSRINCLQQLK---------------------SL 543
            .:|.||||..|:||...| .|...||:|.|  :|:|.|..|:                     ||
Mouse   126 SENHITDISPLNSLTHLL-WLKADGNQLRS--ARMNELPYLQIASFSYNQIIDTEGIFHPRLGSL 187

  Fly   544 NLAGNQIRQINQQDFLGLRCLRELNLKRNKLRRINGFQHLVALERLWLCHNDLHRVDDMASIARA 608
            :|.||:|.|:...|...|..|..|.|:.|:|....|. :|..|:.|:|..|.|.:|:.:.:::..
Mouse   188 DLKGNRIHQVTGLDPERLSSLHTLELRGNQLESTKGI-YLPKLKNLYLAQNLLKKVEGLENLSNL 251

  Fly   609 TRLLEVTIENNPV----------------SLAGDCVSFLVSY-----LPLLQTLSQM--PITEQV 650
            |.|   .:.:|.:                :|..:.:|.|...     ||.|:.|..:  |..::.
Mouse   252 TTL---HLRDNQIETLNGFSQEMKSLQYLNLRSNMISDLAELAKLRDLPKLRALVLLDNPCADET 313

  Fly   651 --RRAALAWRQHKEQAQAAPGSSEAYHNIRREEVISNARTNWELLRSQQTVVGRPKSRLTSELAK 713
              |:.||....|.|:.     ..|.|.:..|.|.        |.:|          .||..|
Mouse   314 DYRQEALVQMAHLERL-----DKEFYEDDDRAEA--------EEIR----------QRLKEE--- 352

  Fly   714 INESNEGPAGEEGEMESEESQQPKELMDELQALIKLPPI 752
                      ::.:::.::..:|           .|||:
Mouse   353 ----------QDQDLDPDQDMEP-----------YLPPV 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13708	NP_647933.1	leucine-rich repeat	449..471	CDD:275380	5/22 (23%)
		PPP1R42	467..661	CDD:455733	60/240 (25%)
		leucine-rich repeat	472..493	CDD:275380	4/20 (20%)
		leucine-rich repeat	494..516	CDD:275380	9/21 (43%)
		leucine-rich repeat	517..539	CDD:275380	9/21 (43%)
		leucine-rich repeat	540..563	CDD:275380	10/43 (23%)
		leucine-rich repeat	564..585	CDD:275380	7/20 (35%)
		leucine-rich repeat	611..637	CDD:275380	6/46 (13%)
Lrrc23	XP_006505721.1	LRR	<100..>266	CDD:443914	48/172 (28%)
		leucine-rich repeat	100..119	CDD:275380	4/18 (22%)
		leucine-rich repeat	120..141	CDD:275380	9/20 (45%)
		leucine-rich repeat	142..162	CDD:275380	9/22 (41%)
		leucine-rich repeat	163..183	CDD:275380	1/19 (5%)
		leucine-rich repeat	184..207	CDD:275380	9/22 (41%)
		PPP1R42	187..331	CDD:455733	37/152 (24%)
		leucine-rich repeat	208..228	CDD:275380	7/20 (35%)
		leucine-rich repeat	229..250	CDD:275380	6/20 (30%)
		leucine-rich repeat	251..273	CDD:275380	3/24 (13%)
		leucine-rich repeat	274..298	CDD:275380	4/23 (17%)