Protein Alignment LeuRS-m and CDC60

DIOPT Version :9

• Sequence 1: NP_647932.1
• Gene: LeuRS-m / 38581
• FlyBaseID: FBgn0027085
• Length: 869
• Species: Drosophila melanogaster
• Sequence 2: NP_015165.1
• Gene: CDC60 / 855943
• SGDID: S000006081
• Length: 1090
• Species: Saccharomyces cerevisiae
• Alignment Length: 957
• Identity: 178/957 - (18%)
• Similarity: 301/957 - (31%)
• Gaps: 310/957 - (32%)

  Fly    59 DSQDKY-----YVLSM-FPYPSGNLHMGHVRVYTIADSVARFQRMCGKNVFQPMGWDSFGLPAEN 117
            ||::.:     ::.|| :||.:|.:|.||....:..:....|:||.||....|:|:...|:|...
Yeast    48 DSEELHRTYPKFMSSMAYPYMNGVMHAGHCFTLSKVEFSIGFERMNGKRALFPLGFHCTGMPILA 112

  Fly   118 AAN--QRGVEPASWTEQNIAQMKEQLKRLGCSFDWNHE--------LSTCSPKYYKWTQHLFLML 172
            .|:  :|..|.......|:...:|::|. ....:.:||        .|..:.|..:......:||
Yeast   113 CADKLKREAELFGKNFDNVPAEEEEIKE-ETPAEKDHEDVTKFKAKKSKAAAKKGRGKYQFEIML 176

  Fly   173 HRHGLAYQNEALVNWDPVDKTVLADEQVDANGCSWRSGAKVEKKLLRQWFIRTSAYAKQLLDGLE 237
            .   |....|.::.:......:.....:..:.|: ..||:::   .|:.|:.|.|      :...
Yeast   177 Q---LGIPREEIIKFADAKYWLTYFPPLCESDCT-SLGARID---WRRSFVTTDA------NPYY 228

  Fly   238 DPTLRDWRDIINLQRHWIGECDGYAFNLLTSASGLLRV---WTTHPEHLKDPHAFLVLRSNHHLS 299
            |..:| |:                 .|.| .|:|.::.   :|.:.|  ||..|.:    :|...
Yeast   229 DAFIR-WQ-----------------MNKL-KAAGKIKFGERYTIYSE--KDGQACM----DHDRQ 268

  Fly   300 KLKGADSLSAANPFAGTTMPVV-FSDEVT--FPPKSDV------YLAAPSFRGEDK--------- 346
            ..:|.    ....:.|..:..: |:|:..  ....||:      |..|.:.|.|..
Yeast   269 SGEGV----TPQEYIGVKIEALEFADDAAKIIDSSSDLDKSKKFYFVAATLRPETMYGQTCCFVS 329

  Fly   347 --------DLWDSYGL----AF-------------------TSNGK--------DEESLSPANWE 372
                    |..|||.:    ||                   |..||        ..:|:.| ...
Yeast   330 PTIEYGIFDAGDSYFITTERAFKNMSYQKLTPKRGFYKPIVTVPGKAFIGTKIHAPQSVYP-ELR 393

  Fly   373 MLRKEVLQAATRLNVGGYRVSSKLKDW-----LISRQRYWGTP--------IPIVHCQKCG---A 421
            :|..|.:.|.....|.....|:...|:     |:.:..|:|..        :||:|.:|.|   |
Yeast   394 ILPMETVIATKGTGVVTCVPSNSPDDYITTKDLLHKPEYYGIKPEWIDHEIVPIMHTEKYGDLTA 458

  Fly   422 VPVPEEQLPVSLPPKD------SPKEAFLCDC--------PKCGEKDAR---------------- 456
            ..:.||:...|  |||      :.|.|:..|.        |..|||..:
Yeast   459 KAIVEEKKIQS--PKDKNLLAEAKKIAYKEDYYTGTMIYGPYKGEKVEQAKNKVKADMIAAGEAF 521

  Fly   457 -----------RETDTMDTFVDSSWYY--------LRYLDAQNSERIFDTALTKKFMPV------ 496
                       |..|.....::..||.        .:.::.....::|...:...|..|
Yeast   522 VYNEPESQVMSRSGDDCIVSLEDQWYVDYGEESWKKQAIECLEGMQLFAPEVKNAFEGVLDWLKN 586

  Fly   497 -------------------------DLYIGGKEHAVLHLYYARFINHFLHSCGLSP---TSEPFS 533
                                     |..|....:.:.||.:..:..:.:...|:|.   |.|.|.
Yeast   587 WAVCRTYGLGTRLPWDEKYLVESLSDSTIYQSFYTIAHLLFKDYYGNEIGPLGISADQMTDEVFD 651

  Fly   534 RL-------------LVQGMVMGRSFR------VKGSGR-YVPE-------TEVEIVNAKKNQAV 571
            .:             |.....:.|.|.      |..||: .:|.       |.|.:...|.....
Yeast   652 YIFQHQDDVKNTNIPLPALQKLRREFEYFYPLDVSISGKDLIPNHLTFFIYTHVALFPKKFWPKG 716

  Fly   572 LKETKEPVVMTWEKMSKSKLNGVEPSDMFNEYGTDTTRLIILADVAPT--------SHRNWSSAT 628
            ::.... :::...|||||..|.:.......::|.|..| |..||...|        |:.|.:...
Yeast   717 IRANGH-LMLNNSKMSKSTGNFMTLEQTVEKFGADAAR-IAFADAGDTVEDANFDESNANAAILR 779

  Fly   629 FPGILNWQKRLWLTLQDFQQAREDQTASDVVPTSEEFLAEDAKLFD----------ARNFYVKGA 683
            ...:..|                   |.::...|.....|....||          ....|.:.|
Yeast   780 LFNLKEW-------------------AEEITKESNLRTGEITDFFDIAFEHEMNALIEKTYEQYA 825

  Fly   684 TFNYRHAQQLSVAISKMQGLTNSLRRTPKHVLRHGKQFERALAAQIIMLAPMAPHFASELWSKFV 748
            ..||::|  |...:...|...:..|....  :.|.....|.:..|.::|||:|||||..::.:.:
Yeast   826 LTNYKNA--LKYGLFDFQAARDYYREASG--VMHKDLIARYIETQALLLAPIAPHFAEYIYREVL 886

  Fly   749 A---------IPGRLNPASQELQWSEDVLAQRWPDIDPAYNLDLSIK 786
            .         .|....|.      .:.|||.    :|...||..||:
Yeast   887 GNQTSVQNAKFPRASKPV------DKGVLAA----LDYLRNLQRSIR 923

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LeuRS-m	NP_647932.1	leuS	40..848	CDD:234743	178/957 (19%)
		LeuRS_core	63..624	CDD:173906	140/770 (18%)
		Anticodon_Ia_like	624..747	CDD:299868	25/132 (19%)
		Anticodon_Ia_like	<723..799	CDD:299868	20/73 (27%)
CDC60	NP_015165.1	leuS_arch	17..1088	CDD:273056	178/957 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0495
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900