Protein Alignment LeuRS-m and lars1b

DIOPT Version :9

• Sequence 1: NP_647932.1
• Gene: LeuRS-m / 38581
• FlyBaseID: FBgn0027085
• Length: 869
• Species: Drosophila melanogaster
• Sequence 2: XP_698279.6
• Gene: lars1b / 569778
• ZFINID: ZDB-GENE-030114-7
• Length: 1176
• Species: Danio rerio
• Alignment Length: 1149
• Identity: 199/1149 - (17%)
• Similarity: 337/1149 - (29%)
• Gaps: 470/1149 - (40%)

  Fly    38 VKHRIEAHWR-----EQLSGGQFNPKDSQDKYYVLSMFPYPSGNLHMGHVRVYTIADSVARFQRM 97
            ::..::..|.     |..:........:::||::...:||.:|.||:||....:..:....:||:
Zfish    16 IEEEVQQKWEQDKLFENEAPATIGENTNKNKYFITFPYPYMNGRLHLGHTFCLSKCEFAVGYQRL 80

  Fly    98 CGKNVFQPMGWDSFGLPAENAAN--QRGVE----PASWTEQN----------------------- 133
            .||....|.|....|:|.:..|:  :|.:|    |..:.|::
Zfish    81 KGKQCLFPFGLHCTGMPIKACADKLKREMELYGYPPQFPEEDEEEEEQKKTSDDVIIKDKTKGKK 145

  Fly   134 ---IAQ----------MK---------------------------EQLKRLGCSFDWNHELST-- 156
               :|:          ||                           |.|||:|...||.....|
Zfish   146 SKAVAKSGSSKFQWDIMKSLGLQDAEIVKFAEAEHWLDYFPPLAVEDLKRMGLKVDWRRSFITTD 210

  Fly   157 CSPKYYKWTQHLFLMLHR-----------------------------HGLAYQNEALVNWDPVD- 191
            .:|.|..:.:..|:.|..                             .|:..|...|:....|:
Zfish   211 VNPFYDSFVRWQFINLKERKKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLIKMKVVEP 275

  Fly   192 ----------KTV------LADEQV------------------DANGCSWRSGAKVEKKLLRQWF 222
                      |||      |..|.:                  .|||..:.|..:..:.:..|.|
Zfish   276 YPTKLGALKGKTVFLVAATLRPETMFGQTNCWIRPDMKYVVFETANGDLFISTQRSARNMSYQGF 340

  Fly   223 IRTSAYAKQLLD---------GLEDPTLRDWRDIINLQRHWIGECDGYAFNLLT----SASGLLR 274
            .:.:.....:::         .|..| |..::.|             ||..:||    ..:|::
Zfish   341 TKENGVVPVIMNIMGQDILGCALSAP-LTSYKTI-------------YALPMLTIKEDKGTGVV- 390

  Fly   275 VWTTHPEHLKDPHAFL-------VLRSNHHLS-------------KLKGADSLSAANPFAGTTMP 319
              |:.|....|..|.|       .||..:.:.             ::.|..:|||         |
Zfish   391 --TSVPSDAPDDIAALRDIKKKQALREKYGIQDFMVLPFEPVPIIEIPGYGNLSA---------P 444

  Fly   320 VVFSDEVTFPPKSD----------VYL--------AAPSFRGE---------------------- 344
            :| .||:....::|          |||        ....|:|:
Zfish   445 LV-CDELKIQSQNDREKLAEAKEKVYLKGFYEGIMLVEGFKGQKVQDVKKPIQKMMVEKGEALIY 508

  Fly   345 ------------DK------DLWD-SYGLAFTSNGKDEESLSPANWEMLRKEVLQAATRLNVGG- 389
                        |:      |.|. .||        :||....|:..:...|.....||.|...
Zfish   509 MEPEKQVLSRSADECVVALCDQWYLDYG--------NEEWKKQAHGVLEHLETFCDETRKNFEAT 565

  Fly   390 ------------YRVSSKL---KDWLI---SRQRYWGTPIPIVHCQKCGAVPVPEEQLPVSLPPK 436
                        |.:.::|   :.|||   |....:.....:.|..: |.|...:...|:.:.|:
Zfish   566 LAWLQEHACSRTYGLGTRLPWNEQWLIESLSDSTIYMAYYTVAHLLQ-GGVLSGQGPSPLGIRPQ 629

  Fly   437 DSPKEAF-----------LCDCPKCGEKDARRETDTMDTFVDSSWYYLRYLDAQNSERIFDTALT 490
            ...:|.:           ..|.||......|||.:        .||
Zfish   630 QMTREVWDYIFFKTSPFPKTDIPKEHLLKLRREFE--------FWY------------------- 667

  Fly   491 KKFMPVDLYIGGKEHAVLHLYYARFINHFLHSCGLSPTSEPFSRLLVQGMVMGRSFRVKGSGRYV 555
                |||:.:.||:....||.|..: ||    ..:.|..                     ||::
Zfish   668 ----PVDVRVSGKDLVPNHLSYYLY-NH----VAMWPND---------------------SGKW- 701

  Fly   556 PETEVEIVNAKKNQAVLKETKEPVVMTWEKMSKSKLNGVEPSDMFNEYGTDTTRLIILADVAPT- 619
                        .|||  .....:::..||||||..|.:..|....::..|..|| .|||...|
Zfish   702 ------------PQAV--RANGHLLLNSEKMSKSTGNFLTLSQAIAKFSADGMRL-ALADAGDTV 751

  Fly   620 SHRNWSSA-TFPGIL------NWQKRLWLTLQDFQQAREDQTASD----------VVPTSEEFLA 667
            ...|:..| ...|||      .|.|.: :..||..:.....|.:|          ::.|.:.:
Zfish   752 EDANFVEAMADAGILRLFTWVEWVKEM-IANQDNLRTGPADTFNDRVFISEMNSGIIKTDQHY-- 813

  Fly   668 EDAKLFDARNFY---VKGATFNYRHAQQ--LSVAISKMQGLTNSLRRTPKHVLRHGKQFERALAA 727
                   .|..|   :|...|.::.|:.  ..:||..|                |.....:.:..
Zfish   814 -------ERMMYKEALKSGFFEFQAAKDKYRELAIEGM----------------HKDLVFQFIEN 855

  Fly   728 QIIMLAPMAPHFASELWSKFVAIPGRLNPASQELQWSEDVLAQRWPDIDPAYNL----------- 781
            |.::|||:.||.....||    :.|:          |..|:..:||...|...:
Zfish   856 QTLLLAPICPHLCEHTWS----LLGK----------SSTVMKAQWPTAGPVDEILIRSSQYLMDT 906

  Fly   782 --DLSIKVNGF-----------------ENCVIKVQRTHLDKVTHSDALDIAFNTESVTSYLIDK 827
              ||.:::..:                 .:|.|.|.:|: ....||....:..:.:|....|.|.
Zfish   907 AHDLRLRLKAYTQPAKGKKGDNKPPAKPTHCTIYVAKTY-PPWQHSALSLLGKHYKSNNGALPDN 970

  Fly   828 KIRTTNFVLYPGIEAILN-----IYVDKAKMKQKPPTTDDAEAQ 866
            |:........|.::..:.     :.:.|..:::..|...|.|.:
Zfish   971 KVIAMELGAMPELKKYMKRVMPFVAMIKDNLEKNGPRVLDLELE 1014

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LeuRS-m	NP_647932.1	leuS	40..848	CDD:234743	195/1127 (17%)
		LeuRS_core	63..624	CDD:173906	145/818 (18%)
		Anticodon_Ia_like	624..747	CDD:299868	28/144 (19%)
		Anticodon_Ia_like	<723..799	CDD:299868	19/105 (18%)
lars1b	XP_698279.6	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0495
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900