Protein Alignment LeuRS-m and IleRS

DIOPT Version :9

• Sequence 1: NP_647932.1
• Gene: LeuRS-m / 38581
• FlyBaseID: FBgn0027085
• Length: 869
• Species: Drosophila melanogaster
• Sequence 2: NP_524840.2
• Gene: IleRS / 45785
• FlyBaseID: FBgn0027086
• Length: 1229
• Species: Drosophila melanogaster
• Alignment Length: 1068
• Identity: 194/1068 - (18%)
• Similarity: 317/1068 - (29%)
• Gaps: 386/1068 - (36%)

  Fly    28 RNDNPELTSDVKHRIEAH-----WR--------EQLSGGQFNPKDSQDKYYVLSMFPYPSGNLHM 79
            |||...:..::....|..     ||        .|||.|       :.||......|:.:|..|.
  Fly     7 RNDVCRVPENINFPAEEENVLQKWRHENIFEKCSQLSKG-------KPKYTFYDGPPFATGLPHY 64

  Fly    80 GHVRVYTIADSVARFQRMCGKNVFQPMGWDSFGLPAE----NAANQRGVEPASWTEQNIA----- 135
            ||:...||.|.|.|:....|.:|.:..|||..|||.|    ...|.:|  |....:..||
  Fly    65 GHILAGTIKDIVTRYAYQQGYHVDRRFGWDCHGLPVEFEIDKLLNIKG--PEDVAKMGIAAYNAE 127

  Fly   136 ----------QMKEQLKRLGCSFDWNHELSTCSPKYYKWTQHLFLMLHRHGLAYQNEALVNWDPV 190
                      :.:..:.|:|...|:.::..|..|.|.:....:|..|...||.||...::.:...
  Fly   128 CRKIVMRYADEWENVVTRVGRWIDFKNDYKTLYPWYMESIWWIFKQLFDKGLVYQGVKVMPYSTA 192

  Fly   191 DKTVLADEQVDANGCSWRSGAKVEKKLLRQWFIRTSAYAKQLLDGLEDPTLRDWRDIINLQRHWI 255
            ..|.|::.:.:.|                                        ::::::
  Fly   193 CTTSLSNFEANQN----------------------------------------YKEVVD------ 211

  Fly   256 GECDGYAFNLLTSASGLLRVWTT-------------HP-------EHLKDPHAFLVLRSNHHLSK 300
             .|...|...::..:....||||             ||       ..:|....|::..|  .||.
  Fly   212 -PCVVVALEAVSLPNTFFLVWTTTPWTLPSNFACCVHPTMTYVKVRDVKSDRLFVLAES--RLSY 273

  Fly   301 L-KGADSLSAANPFAGTTMP----------------------VVFSDEVTFPPKSDVYLAAPSFR 342
            : |..........|.|.|:.                      |:..:.||....:.:...||.|.
  Fly   274 VYKSETEYEVKEKFVGKTLKDLHYKPLFPYFAKRGAEVKAYRVLVDEYVTEDSGTGIVHNAPYFG 338

  Fly   343 GEDKDLWDSYGL---------------AFTSNGKDEE---------------------------- 364
            .:|..:..:.||               .||:...|.|
  Fly   339 EDDYRVCLAAGLITKSSEVLCPVDEAGRFTNEASDFEGQYVKDSDKQIMAALKARGNLVSSGQVK 403

  Fly   365 --------SLSP------ANW----EMLRKEVLQAATRLN-----VGGYRVSSKLK---DWLISR 403
                    |.:|      .:|    |.:.|.:|..:::..     |...|..:.||   ||.|||
  Fly   404 HSYPFCWRSDTPLIYKAVPSWFVRVEHMSKNLLDCSSQTYWVPDFVKEKRFGNWLKEARDWAISR 468

  Fly   404 QRYWGTPIPI-----------------------VHCQKCGAVPVPEEQLPVSLPPKDSPKEAFLC 445
            .|||||||||                       |..:......:...::|.::|
  Fly   469 NRYWGTPIPIWRSPSGDETVVIGSIKQLAELSGVQVEDLHRESIDHIEIPSAVP----------- 522

  Fly   446 DCPKCGEKDARRETDTMDTFVDSSWYYLRYLDAQNSERIFDTALTKKFM---PVDLYIGGKEHAV 507
                 |....||.....|.:.:|.       ....:::.|.....|.||   |.|....|.:...
  Fly   523 -----GNPPLRRIAPVFDCWFESG-------SMPFAQQHFPFENEKDFMNNFPADFIAEGIDQTR 575

  Fly   508 LHLYYARFINHFLHSCGLSPTSEPFSRLLVQGMVMGRSFRVKGSGRYVPETEVEIVNAKKNQAVL 572
            ...|....|:..|.:      ..||..|:..|:|:...
  Fly   576 GWFYTLLVISTALFN------KAPFKNLIASGLVLAAD--------------------------- 607

  Fly   573 KETKEPVVMTWEKMSKSKLNGVEPSDMFNEYGTDTTRL-IILADVAPTSHRNWSSATFPGI---- 632
                      .:||||.|.|..:|.::.::||.|..|| :|.:.|.......:.......|
  Fly   608 ----------GQKMSKRKKNYPDPMEVVHKYGADALRLYLINSPVVRAESLRFKEEGVRDIIKDV 662

  Fly   633 -LNWQKRLWLTLQDFQQAREDQTASDVVPTSE--------------------------EFLAEDA 670
             |.|.......||:..:..::..|.:...|.:                          ||.|.:.
  Fly   663 FLPWYNAYRFLLQNIVRYEKEDLAGNGQYTYDRERHLKNMDKASVIDVWILSFKESLLEFFATEM 727

  Fly   671 KLF--------------DARNFYVKGATFNYRHAQQLSVAISKMQGLTNSLRRTPKHVLRHGKQF 721
            |::              ...|:||:   .|.|..:....|...:|.|..               .
  Fly   728 KMYRLYTVVPRLTKFIDQLTNWYVR---LNRRRIKGELGADQCIQSLDT---------------L 774

  Fly   722 ERALAAQIIMLAPMAPHFASELWSKFVAIPGRLNPASQELQWSEDVLAQRWP---------DIDP 777
            ...|...:.|:||..|:....::.:.|.    ..||. .|:.::.|..|..|         ||:.
  Fly   775 YDVLYTMVKMMAPFTPYLTEYIFQRLVL----FQPAG-TLEHADSVHYQMMPVSQKKFIRNDIER 834

  Fly   778 AYNLDLSIKVNGFENCVIKVQRTHLDKVTHSDALDIAFNTESVTSYLIDKKIRTTNFVLYPGIEA 842
            :..|..|         |:::.|...|:.|    |.:.:....:.:...|.:|......|...|.:
  Fly   835 SVALMQS---------VVELGRVMRDRRT----LPVKYPVSEIIAIHKDSQILEAIKTLQDFILS 886

  Fly   843 ILNI-YVDKAKMKQKPPTTDDAEAQPQA 869
            .||: .:..:..|:|...|..||...:|
  Fly   887 ELNVRKLTLSSDKEKYGVTLRAEPDHKA 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LeuRS-m	NP_647932.1	leuS	40..848	CDD:234743	185/1033 (18%)
		LeuRS_core	63..624	CDD:173906	132/718 (18%)
		Anticodon_Ia_like	624..747	CDD:299868	24/167 (14%)
		Anticodon_Ia_like	<723..799	CDD:299868	17/84 (20%)
IleRS	NP_524840.2	PLN02882	9..1094	CDD:215477	192/1066 (18%)
		IleRS_core	47..>189	CDD:173909	38/143 (27%)
		IleRS_core	<373..650	CDD:173909	63/342 (18%)
		Anticodon_Ia_Ile_ABEc	650..847	CDD:153415	36/228 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446763
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840