Protein Alignment LeuRS-m and LeuRS

DIOPT Version :10

• Sequence 1: NP_647932.1
• Gene: LeuRS-m / 38581
• FlyBaseID: FBgn0027085
• Length: 869
• Species: Drosophila melanogaster
• Sequence 2: XP_317169.3
• Gene: LeuRS / 1277687
• VectorBaseID: AGAMI1_001636
• Length: 1195
• Species: Anopheles gambiae
• Alignment Length: 1023
• Identity: 180/1023 - (17%)
• Similarity: 278/1023 - (27%)
• Gaps: 416/1023 - (40%)

  Fly    33 ELTSDVKHRIEAHWREQLSGGQFNPKD----SQDKYYVLSMFPYPSGNLHMGHVRVYTIADSVAR 93
            |....::..|:..|:.........||:    ..:|:.|...:||.:|.||:||....:.|:...|
Mosquito    16 EYLQKIEREIQERWQRDKVYDVDAPKEPRKADDEKFLVTFPYPYMNGRLHLGHAFSLSKAEFAVR 80

  Fly    94 FQRMCGKNVFQPMGWDSFGLPAENAANQ----------------------------RGVEPA--- 127
            :.|:.||.|..|:|:...|:|.:..|::                            |.|.|.
Mosquito    81 YHRLKGKKVLFPLGFHCTGMPIKACADKLKREIELYGCPPVFPREEALAVVEKPEDRDVVPKDKS 145

  Fly   128 ----------------SW--------TEQNIAQMK--------------EQLKRLGCSFDWNHEL 154
                            .|        |:..||:..              ..||.||...||....
Mosquito   146 KGKKSKATAKAGTAKFQWQIMQSLGLTDDEIAKFANTDHWLDYFPPLAIRDLKELGAHIDWRRTF 210

  Fly   155 ST--CSPKY---YKWT-QHL-----FLMLHRH--------------------GLAYQNEALVNWD 188
            .|  .:|.|   .:|. .||     .:...||                    |:..|...||...
Mosquito   211 ITTDANPFYDSFVRWQFNHLKARGKIMYGKRHTIFSPKDGQPCMDHDRSSGEGVGPQEYTLVKMK 275

  Fly   189 PVDK-------------------TVLADEQVDANGC-----------------SWRSGAKVEKKL 217
            ...|                   |:..:.......|                 .|....:..:.:
Mosquito   276 VTGKMPSKLASAAGKRPVYLVCGTLRPETMYGQTNCWVHPDIKYIAFETAKQEVWVCTRRAARNM 340

  Fly   218 LRQWFIRTSAYAKQLLDGLEDPTLRDWRDIINLQ-------RHWIGECDGYAFNLLT----SASG 271
            ..|.|.......|:|.:.:       .:||:.||       ...|     ||..:|:    ..:|
Mosquito   341 SYQGFTAVEGEIKELAELV-------GQDIMGLQLSAPLTSNKVI-----YALPMLSIKEDKGTG 393

  Fly   272 LLRVWTTHPEHLKDPHAFLVLRSNHHLSKLKGADSLSAANPFA---GTTMPVVFSDEVTFP---- 329
            ::   |:.|....|.:|.||              .|....||.   |.|      ||:..|
Mosquito   394 IV---TSVPSDSPDDYAALV--------------DLQKKQPFREKYGIT------DEMVLPYQPI 435

  Fly   330 PKSDV--------YLAAPSFR----------GEDKDL------WDSYGLAFTSNGKDEESL---- 366
            |..||        ..|...|:          .|.|:|      :|...|.....||..:.:
Mosquito   436 PIIDVPGLGNLCAVYAYDKFKIQSQNDREKLTEAKELVYLKGFYDGVMLVGEHKGKKVQDVKKDL 500

  Fly   367 ----------------------------------------SPANWEMLRKEVLQAATRLNVGGYR 391
                                                    ..|.|:....|.|:.....:....|
Mosquito   501 KQYLVDRNEADVYYEPEKTIMSRSGDVCVVALCNQWYLNYGEAVWQKQTTEHLRTMELFHEEVSR 565

  Fly   392 VSSKLKDWL----ISRQRYWGTPIP---------------------IVHCQKCGAVPVPEEQLPV 431
            ......|||    .||....||.:|                     :.|..:.|:.. .|:..|:
Mosquito   566 NFEHCLDWLHEYACSRTYGLGTKLPWDQQWLIESLSDSTIYMAFYTVAHLLQAGSFR-GEKPSPL 629

  Fly   432 SLPPKDSPKEAFLCDCPKCGEKDARRETDTMDTFVDSSWYYLRYLDAQ--NSERIFDTA---LTK 491
            .:..:|...|.                           |.|:.:.||:  ...|:...|   |.:
Mosquito   630 GITAEDMTPEV---------------------------WDYIFFADAKPPAKSRVKRDAWEQLKR 667

  Fly   492 KF---MPVDLYIGGKE----HAVLHLYYARFINHFLHSCGLSPTSEPFSRLLVQGMVMGRSFRVK 549
            :|   .||||.:.||:    |....||     ||    ..:.|.         ......:..|..
Mosquito   668 EFNFWYPVDLRVSGKDLIQNHLTFFLY-----NH----VAIWPK---------DASKWPKGVRCN 714

  Fly   550 GSGRYVPETEVEIVNAKKNQAVLKETKEPVVMTWEKMSKSKLNGVEPSDMFNEYGTDTTRLIILA 614
            |.                           :::...|||||..|.:...:...::..|.||| .||
Mosquito   715 GH---------------------------LLLNSAKMSKSDGNFLTLYESIAKFSADGTRL-CLA 751

  Fly   615 DVAPTSHRNWSSATF------PGIL------NWQKRLWLTLQDFQQAREDQTASDVVPTSEEFLA 667
            |...:.    ..|.|      .|||      .|.|....:....::..:|.:.:|.|.:||
Mosquito   752 DAGDSI----EDANFVVTNADAGILRLYTFIEWVKETLASKPLLRKGPQDASINDQVFSSE---- 808

  Fly   668 EDAKLFDARNFYVKGATFNYR---HAQQLSVAISKMQGLTNSLRRTPKHVLRHGKQFERALAAQI 729
                    .|...|....:||   ..:.|.....:.|...:..|........|.......:..|.
Mosquito   809 --------MNLLTKQTDEHYRKMLFKEALRTGFFEFQTARDKYRELCGSNGMHASLVMEFIQRQA 865

  Fly   730 IMLAPMAPHFASELWSKFVAIPGRLNPASQELQWSEDVLAQRWPDIDP 777
            :::||:.||.|..:|...:.     |..|        :|...||.:.|
Mosquito   866 LLIAPICPHVAEHIWCDLLG-----NKTS--------ILHAAWPAVGP 900

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LeuRS-m	NP_647932.1	LeuS	40..848	CDD:440261	179/1016 (18%)
LeuRS	XP_317169.3	None