Protein Alignment LeuRS-m and lars2

DIOPT Version :10

• Sequence 1: NP_647932.1
• Gene: LeuRS-m / 38581
• FlyBaseID: FBgn0027085
• Length: 869
• Species: Drosophila melanogaster
• Sequence 2: XP_002938354.3
• Gene: lars2 / 100379697
• XenbaseID: XB-GENE-956205
• Length: 900
• Species: Xenopus tropicalis
• Alignment Length: 899
• Identity: 374/899 - (41%)
• Similarity: 524/899 - (58%)
• Gaps: 100/899 - (11%)

  Fly    16 NSWRRLLT-------QSCTRNDNPELTSDVKHRIEAHWREQLSGGQFNP----KDSQDKYYVLSM 69
            |:|::..:       .|.|.....|...:.:.::|..|:.::. .:|..    ..|:.|:|||||
 Frog    22 NNWQKATSLNVIQSIYSETGKWEKEYGLETRKKVENWWKPKVK-ERFTKISKVDKSKPKFYVLSM 85

  Fly    70 FPYPSGNLHMGHVRVYTIADSVARFQRMCGKNVFQPMGWDSFGLPAENAANQRGVEPASWTEQNI 134
            ||||||.|||||||||||:|::||||:|.|..|..|||||:|||||||||.:.|:.|.:|||:||
 Frog    86 FPYPSGKLHMGHVRVYTISDAIARFQKMRGMQVINPMGWDAFGLPAENAAIEHGLRPDTWTERNI 150

  Fly   135 AQMKEQLKRLGCSFDWNHELSTCSPKYYKWTQHLFLMLHRHGLAYQNEALVNWDPVDKTVLADEQ 199
            ..|:|||.|:|..|:|:.|::|||..||||||:|||.::..|||||.||:|||||||:||||:||
 Frog   151 QHMREQLDRIGLCFNWDREITTCSGDYYKWTQYLFLKMYEAGLAYQKEAMVNWDPVDQTVLANEQ 215

  Fly   200 VDANGCSWRSGAKVEKKLLRQWFIRTSAYAKQLLDGLEDPTLRDWRDIINLQRHWIGECDGYAFN 264
            ||.||||||||||||:|.|:|||::|:.|||.:.|.|.|  |.:|..:.::|.:|||||:|..|:
 Frog   216 VDENGCSWRSGAKVEQKYLKQWFLKTTVYAKDMSDALAD--LPEWYGVKSMQANWIGECNGCFFD 278

  Fly   265 LLTSASGL-----LRVWTTHPEHLKDPHAFLVLRSNHHLSKLKGADSL----------------- 307
            .:....|:     :..::..||.:... :::.:..||.|  |.||.||
 Frog   279 CMLKIDGVETGETISAYSFKPEAVFGA-SYVAILPNHRL--LHGASSLKEALQKAYTKGKDCVTR 340

  Fly   308 -SAANPFAGTTMPVVFSDEVTFPPKSDVYLAAPSFRGEDKDLWDSYGLAF-----TSNGKDEESL 366
             ||.|.|....:|||.|.:..|....|..:..||...||.:|.|..||.:     |||...|...
 Frog   341 VSALNLFTKQEVPVVISAKTEFEGYLDTKIGIPSATPEDAELADKLGLLYVKVIETSNDGTEMIC 405

  Fly   367 SPANWEMLRKE-----VLQAATRLNVGGYRVSSKLKDWLISRQRYWGTPIPIVHCQKCGAVPVPE 426
            :...:..|.::     :.|.|:...|||:..|.||:|||||||||||||||::||..||.||||.
 Frog   406 NSGKFTGLSRQEAFLAITQQASSEGVGGHLTSDKLRDWLISRQRYWGTPIPVIHCPSCGTVPVPY 470

  Fly   427 EQLPVSLP-----------PKDSPKEAFLCDCPKCGEKDARRETDTMDTFVDSSWYYLRYLDAQN 480
            |.|||.||           |..|..|...|.||:| ...|.||||||||||||:||||||.|..|
 Frog   471 EDLPVLLPSAASFTGKGLSPLASASEWINCKCPRC-TGAASRETDTMDTFVDSAWYYLRYTDPLN 534

  Fly   481 SERIFDTALTKKFMPVDLYIGGKEHAVLHLYYARFINHFLHSCGLSPTSEPFSRLLVQGMVMGRS 545
            |||.||.|....:||||||||||||||:|||||||.|||..|.|::...|||.:|||||::.|::
 Frog   535 SERPFDKAWADFWMPVDLYIGGKEHAVMHLYYARFFNHFCSSQGMTKHREPFHKLLVQGLIKGQT 599

  Fly   546 FRVKGSGRYVPETEVEIVNAKKNQAVLKETKEPVVMTWEKMSKSKLNGVEPSDMFNEYGTDTTRL 610
            :::..:|||:.::||:....   :....||.|.:::|||||||||.|||:|.::..:||.|||||
 Frog   600 YKLASTGRYLKKSEVDDTGF---EPAYLETGEKLLVTWEKMSKSKHNGVDPQEIVEQYGIDTTRL 661

  Fly   611 IILADVAPTSHRNWSSAT--FPGILNWQKRLWLTLQDFQQAREDQTASDVVPTSEEFLAEDAKLF 673
            .:|....|.....|...|  .||:..||.|||.....|.:||:..:..:....:::.:||..:::
 Frog   662 YLLFAAPPEQDILWDVKTDAIPGVRRWQTRLWTITSKFIEARKSSSVPNPHLLNKKEVAEARRIW 726

  Fly   674 DARNFYVKGATFNYRHAQQLSVAISKMQGLTNSLRRTPKHVLRHGKQFERALAAQIIMLAPMAPH 738
            ::||..|...|.::......:.|||::..|:|:|.:....|:.|..:||.|||:..||:||||||
 Frog   727 ESRNLAVLEVTSHFTEDYLFNAAISQLMSLSNTLSQASSRVILHSSEFEDALASLCIMVAPMAPH 791

  Fly   739 FASELWSKFVAIPGRLNPASQELQWSEDVLAQRWPDIDPAY-----NLDLSIKVNGFENC----- 793
            .|||||.....:..:|   ..:.:|.:|||.|.||.||..|     .:::.:.:|. ::|
 Frog   792 LASELWKGMAHVQNKL---CTQYKWDKDVLVQHWPSIDTDYLKQPDIVEVQVLINN-KSCGTVGV 852

  Fly   794 ---------VIK--VQRTHLDKVTHSDALDIAFNTESVTSYLIDKKIRTTNFVL 836
                     |::  |.:::|. |||       ....::|...:..:....||::
 Frog   853 PQEVSRDSKVVQEMVLQSNLG-VTH-------LQGRTITKVFLSPRTALINFLV 898

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LeuRS-m	NP_647932.1	LeuS	40..848	CDD:440261	369/868 (43%)
lars2	XP_002938354.3	LeuS	74..898	CDD:440261	366/844 (43%)