Protein Alignment Dhc64C and sac

DIOPT Version :10

• Sequence 1: NP_001261432.1
• Gene: Dhc64C / 38580
• FlyBaseID: FBgn0261797
• Length: 4661
• Species: Drosophila melanogaster
• Sequence 2: NP_649475.3
• Gene: sac / 40568
• FlyBaseID: FBgn0037254
• Length: 1079
• Species: Drosophila melanogaster
• Alignment Length: 1431
• Identity: 246/1431 - (17%)
• Similarity: 464/1431 - (32%)
• Gaps: 576/1431 - (40%)

  Fly   304 LKHGKRFHATVSFDTDTGLKQALATVADYNPLMKDFPINDLLSATELEKI------RPAV----- 357
            |:.|:.:..:..||     :.:.:::::..|       :|.....|.||.      ||..
  Fly     6 LEVGQNYEGSQEFD-----ESSTSSISNKGP-------DDSQFKREAEKAICIMPPRPGTTMMNY 58

  Fly   358 QQIFAHLRKVRNTKYPI---QRCLKLIEAISR----DLSQQLLKVLGTRRL--MHIPFD-EFERV 412
            |:::....::.:..|||   ||.|.|::.:.:    .|...|.||:.||.:  .|:|.| |.:|.
  Fly    59 QELYIPRNQLTDVYYPIQEAQRWLTLMDKMGKAHRFPLPTILPKVIQTRYVPKRHLPKDVEVDRR 123

  Fly   413 MNQCFEIFSCWDDEYDKLQ--------GLLRDIVKKKRDEHLKMVWRVSPAHKKLQTRMEHMRKF 469
            ..|           |.|:.        ||..|:::...:::            .:.:......||
  Fly   124 RRQ-----------YQKINLVNELAKAGLTDDVLQPTEEQY------------NVMSEFAFPHKF 165

  Fly   470 RRQHEQLRTVILRVLRPTKPAVGDDGNVVETKQP-------------YSLDAADANAIEEVNLAY 521
            ...:                  .||.| .:...|             |.|.|       :..|.|
  Fly   166 PLSY------------------FDDSN-FDINSPAAWFELGVVGDAHYPLPA-------KAYLPY 204

  Fly   522 ENVKEVDCLDITKEGSEAWEAAVKRYEEKIDRVETRITAHLRDQLGTAKNANEMFRIFS------ 580
             |...::|         .|..|.             :|||..|        ::::.:.|
  Fly   205 -NQSLLNC---------QWGMAA-------------VTAHHED--------SDLWTLLSLEDGCT 238

  Fly   581 ------RFNALFVRPH-----IRGAIRE----YQTQLIQRVKDDIEALHEKFKVQYPQSKSCRLS 630
                  :|..:...||     ::.|:.|    .|..|::.:.|.:  |||
  Fly   239 YTVPKLQFMFMAEDPHKYIKRLQAAVHERHKGEQLMLMELIVDCV--LHE--------------- 286

  Fly   631 SVRDLPPVAGSIIWARQIDNQLTMYLKRVEDVLGKGWETHIEGQKLKADGDSFRAKLSISDVFHE 695
                            .|::.:....|.:|.||.                   .||:|
  Fly   287 ----------------DIESTVFYSFKPIESVLQ-------------------AAKVS------- 309

  Fly   696 WARKVQERNFGSTGRIFTIESTRSRIGRGNVLRLRVNFLPE-----------IITLAKEVRNIKN 749
                               |..:.|      ||..||.:.|           |:.:.||....:|
  Fly   310 -------------------EQCKRR------LRSEVNLVFERLMALYELEQFILKMPKEFPQFRN 349

  Fly   750 LGFRVPLTIVNKAHQANQIYPYAISLIESVRTYERTLEKLNNRSLAQNSVFKIED--RASIVPLV 812
            :..:             :..|.:.::..|.:      |:|..::|......|..|  :||:...|
  Fly   350 INLK-------------EFLPRSFAVDVSGK------ERLELQALGITMQEKRYDYLKASLFYCV 395

  Fly   813 AGLRKDVLNLVSEGIGLIWESYKLDPYVIRLSECVTQFQEK---VDDLLVVEEQLDVDVRSLETC 874
            .|:.      ...|:.:..:      |:..||..:..|.:.   ||.|...|...|
  Fly   396 GGIE------AMAGVAIECQ------YIETLSIFICSFSKPLALVDFLQAQEAHSD--------- 439

  Fly   875 PYSAATFVE---------ILSKIQHAVD----DLSLRQYS-----NLSVWVTRLDEEVEKKLALR 921
              :.|||::         :::.:..|:.    |:||..::     .:|.::.::...:::.:.:.
  Fly   440 --NVATFLKVYWPQQLTTVITVVLRALGKGWLDISLNTWTVYLMCKISRFILQVKFRMQESMEVL 502

  Fly   922 LQAGIQAWTE----------ALTGNKKEVDTSMDTDAPAQ-PTHKLGGDPQIQNAVHEIRITNQQ 975
            |:..:..::.          .|..|.|..:..:||:.|.| |...:           .:.|:..:
  Fly   503 LETSLMNFSHFVCDPCLQFLELKSNYKWTNNYIDTEFPFQKPVFAM-----------TLGISEDR 556

  Fly   976 MYLY--------PSIEEARFQIMQQFFAWQAI---VTSQVRLQSTRYQVGLEKHVSQTYRNLLTK 1029
            ...|        |.:.|...:.:::....:.|   |.|.::.....|.:.:|....:..|
  Fly   557 KVFYSTDPDEFQPGLVEIFKKCLEKSSGVRCIDGSVMSFLKFAPNLYILTVELIEDRFLR----- 616

  Fly  1030 LPEGKILENAYGAIEQKVSEVRNYVDEWLRYQSLWDLQADMLYGRLGEDVNLWIKCLNDIKQSRT 1094
              |.::|:|.|.   :.|..:|.|...:.|:...:.|           :||.:::.     .::.
  Fly   617 --ENELLKNCYA---KAVLPLRAYARLYERFIDFYLL-----------NVNTYMQA-----YAQA 660

  Fly  1095 TFDTSDTRRAYGPIIIDYAKVQAKVTLKYDSWHKEALGKFGTLLGTEMTSFHSKVSKSRTDLEMQ 1159
            ...:|:.:|.    |::..:::.::        :|.|..|.|:     ..|:..|...:..:..:
  Fly   661 HKPSSEVKRD----ILENKRLKEEL--------REILPAFITI-----GPFYINVDTMKQFMIKK 708

  Fly  1160 SIEAASTSDAVSFITYVQSL-KKDMIAWDKQVEVFREAQRILER--------QRFQFPNT----- 1210
            .||....    .|..||..: :.:.:..|:.:|:||   ||.||        :...|..|
  Fly   709 RIEVVRR----IFEYYVDRMYETNEVLLDRCLEMFR---RIAERPISIEHLYEIRDFAQTVPDLV 766

  Fly  1211 ----------WLHVDNIEG------------EWSAF---NEIIKRKDTAIQTQVASLQAKIVAED 1250
                      ||..|.::.            :|:.:   ::|:.|..|....|...::
  Fly   767 DELKADIQVMWLEYDLLDSFFYNLSDHQFAMKWNVYAWPHQIMVRLSTLKDEQKVDIE------- 824

  Fly  1251 KAVETRTVDFLNDWEKTKPTGGKIRPDDALQQLQIFESKYSRLKEERDNVVKAKEALELQESAVP 1315
                    |||           ::...:.    |.||.:...|.:|          ::....|..
  Fly   825 --------DFL-----------RLHASEC----QAFEERLESLNDE----------VQAYSLAFN 856

  Fly  1316 NNSAERMNVALEELQDLRGVWS---ELSKVWTQIDETREKPWLSVQPRKLRQQLEAMMAQLKELP 1377
            .|.|:..:|      |::..|:   ||.||              .|..:.||:|    .:|:.|
  Fly   857 TNRAQETSV------DIKKTWALIKELEKV--------------SQTLQFRQEL----FELEPL- 896

  Fly  1378 ARLRMYESYEYVKKLIQSYIKVNMLIVELKSDALKERHWKQLTKQLRVNWVLSDLSLG------- 1435
                   |.|:::.:|.|:.....|             |......|:    |.|.:||
  Fly   897 -------SVEFLESIIASFTPYKNL-------------WYGCANFLK----LEDATLGNPIAQLD 937

  Fly  1436 --QVWDVNLQK-----NEGI-----VKDIILVAQGEMA-LEEF------LKQVR-ESWQN---YE 1477
              .||: ||.:     ||.:     ..:|:.||:..:| :::|      :|.:| |:|..   .|
  Fly   938 LEDVWN-NLMRLRDELNESMKIFHEKVEIMDVAKTFIAKIDDFVPVYNSIKDIRNENWMYIHWQE 1001

  Fly  1478 LDLI-----------NYQNKCRIIRGWDDLFNKVKEHINSVAA-MKLSPYYKVFEEEALTWEEKL 1530
            |..|           |||...|  :|..|:..:|  ||.|..| .:.....:..|||....:.:|
  Fly  1002 LSAITGQEIKYSVAMNYQYLIR--KGILDVLPEV--HIISEKANNEAEEIRRAIEEEERRKQAEL 1062

  Fly  1531 N 1531
            |
  Fly  1063 N 1063

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhc64C	NP_001261432.1	DHC_N1	242..839	CDD:462457	98/610 (16%)
		DYN1	1022..4338	CDD:227570	113/594 (19%)
		Dynein_C	4343..4656	CDD:465677
sac	NP_649475.3	DHC_N2	901..>1042	CDD:462462	38/162 (23%)