DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhc64C and Dync1h1

DIOPT Version :9

Sequence 1:	NP_001261432.1	Gene:	Dhc64C / 38580	FlyBaseID:	FBgn0261797	Length:	4661	Species:	Drosophila melanogaster
Sequence 2:	NP_084514.2	Gene:	Dync1h1 / 13424	MGIID:	103147	Length:	4644	Species:	Mus musculus

Alignment Length:	4663	Identity:	3343/4663 - (71%)
Similarity:	3953/4663 - (84%)	Gaps:	68/4663 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SIANYDAFANYLRKAVTILLPEDDVVPASLNDALDDPVNQDTIRKFLSDPQVQALYVQRNCIKED 83
            ::|:......:|||.|.:||.:....||:|..||::....:.:|||||||||..:.|:|:.:|||
Mouse    21 NVADVAVLQKHLRKLVPLLLEDGGDAPAALEAALEEKSALEQMRKFLSDPQVHTVLVERSTLKED 85

  Fly    84 DSEQPAEGEDEKEQVTYQISNDVHFTNSRMASLACIKRGLVVEADKSIHSQLRLINFSDGSPYET 148
            ..:   |||:|||.::|.|:.|:|: ..:..|||.|||..|::|||.:.||||::..|:.|||||
Mouse    86 VGD---EGEEEKEFISYNINIDIHY-GVKSNSLAFIKRAPVIDADKPVSSQLRVLTLSEDSPYET 146

  Fly   149 LHAFISKSLAPYFKSYVKESGRADRDGDKMAPSVEKKLAELEMGLLHLQQNIDIPEITLTAHQTV 213
            ||:|||.::||:||||::|||:|||||||||||||||:||||||||||||||:||||:|..|..:
Mouse   147 LHSFISNAVAPFFKSYIRESGKADRDGDKMAPSVEKKIAELEMGLLHLQQNIEIPEISLPIHPII 211

  Fly   214 NNVIRKCAEENRKAKVADFGDKVEDSSFLNLLQNGVNRWIAEIKKVTKLNRDPGSGTALQEISFW 278
            .||.::|.|...|.||.||||||||.:|||.||:||||||.||:|||||:|||.|||||||||||
Mouse   212 TNVAKQCYERGEKPKVTDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFW 276

  Fly   279 LNLERALYRIQEKRESPEVALTLDILKHGKRFHATVSFDTDTGLKQALATVADYNPLMKDFPIND 343
            |||||||||||||||||||.||||||||||||||||||||||||||||.||.||||||||||:||
Mouse   277 LNLERALYRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLND 341

  Fly   344 LLSATELEKIRPAVQQIFAHLRKVRNTKYPIQRCLKLIEAISRDLSQQLLKVLGTRRLMHIPFDE 408
            |||||||:|||.|:..||.||||:|||||||||.|:|:||||||||.|||||||||:|||:.::|
Mouse   342 LLSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEE 406

  Fly   409 FERVMNQCFEIFSCWDDEYDKLQGLLRDIVKKKRDEHLKMVWRVSPAHKKLQTRMEHMRKFRRQH 473
            ||:||..|||:|..|||||:|||.|||||||:||:|:||||||::|||:|||.|::.||||||||
Mouse   407 FEKVMVACFEVFQTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQH 471

  Fly   474 EQLRTVILRVLRPTKPAVGDDGNVVETKQPYSL-------DAADANAIEEVNLAYENVKEVDCLD 531
            ||||.||:|||||...||... |..|..:|..:       ||||||||||||||||||||||.||
Mouse   472 EQLRAVIVRVLRPQVTAVAQQ-NQGEAPEPQDMKVAEVLFDAADANAIEEVNLAYENVKEVDGLD 535

  Fly   532 ITKEGSEAWEAAVKRYEEKIDRVETRITAHLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIR 596
            ::|||:||||||:|||:|:||||||||||.|||||||||||||||||||||||||||||||||||
Mouse   536 VSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIR 600

  Fly   597 EYQTQLIQRVKDDIEALHEKFKVQYPQSKSCRLSSVRDLPPVAGSIIWARQIDNQLTMYLKRVED 661
            |||||||||||||||:||:|||||||||::|::|.|||||||:||||||:|||.|||.|:|||||
Mouse   601 EYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTAYMKRVED 665

  Fly   662 VLGKGWETHIEGQKLKADGDSFRAKLSISDVFHEWARKVQERNFGSTGRIFTIESTRSRIGRGNV 726
            |||||||.|:||||||.||||||.||:..::|.:||||||:||.|.:||||||||.|.|...|||
Mouse   666 VLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTIESARVRGRTGNV 730

  Fly   727 LRLRVNFLPEIITLAKEVRNIKNLGFRVPLTIVNKAHQANQIYPYAISLIESVRTYERTLEKLNN 791
            |:|:||||||||||:|||||:|.|||||||.||||||||||:||:||||||||||||||.|
Mouse   731 LKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCE---- 791

  Fly   792 RSLAQNSVFKIEDRASIVPLVAGLRKDVLNLVSEGIGLIWESYKLDPYVIRLSECVTQFQEKVDD 856
                     |:|:|.:|..|||||:|:|..|::|||.|:||||||||||.||:|.|..|||||||
Mouse   792 ---------KVEERNTISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKVDD 847

  Fly   857 LLVVEEQLDVDVRSLETCPYSAATFVEILSKIQHAVDDLSLRQYSNLSVWVTRLDEEVEKKLALR 921
            ||::||::|::|||||||.|...||.|||:::|.|||||:|..||||.:||.:||.|:|:.|.:|
Mouse   848 LLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWVNKLDMEIERILGVR 912

  Fly   922 LQAGIQAWTEALTG---NKKEVDTSMDTDAPAQPTHKLGGDPQIQNAVHEIRITNQQMYLYPSIE 983
            ||||::|||:.|.|   :|.|||  |||||| |.:||.||:|:|:|.|||:|||||.:||.|.||
Mouse   913 LQAGLRAWTQVLLGQAEDKAEVD--MDTDAP-QVSHKPGGEPKIKNVVHELRITNQVIYLNPPIE 974

  Fly   984 EARFQIMQQFFAWQAIVTSQVRLQSTRYQVGLEKHVSQT---YRNLLTKLPEGKI-LENAYGAIE 1044
            |.|:::.|:.|||:.:|.|..|:||.|||||:...:::.   |||.||::|:|.: ||.:|.|:.
Mouse   975 ECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYRNALTRMPDGPVALEESYSAVM 1039

  Fly  1045 QKVSEVRNYVDEWLRYQSLWDLQADMLYGRLGEDVNLWIKCLNDIKQSRTTFDTSDTRRAYGPII 1109
            ..|:||..||..||:||.|||:||:.:|.|||||:|.|...|..|:::|.|||.::|::.:||::
Mouse  1040 GIVTEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQALLVQIRKARGTFDNAETKKEFGPVV 1104

  Fly  1110 IDYAKVQAKVTLKYDSWHKEALGKFGTLLGTEMTSFHSKVSKSRTDLEMQSIEAASTSDAVSFIT 1174
            |||.|||:||.|||||||||.|.|||.:||:.||.|||::||||.:||..|::.|||||||:|||
Mouse  1105 IDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFIT 1169

  Fly  1175 YVQSLKKDMIAWDKQVEVFREAQRILERQRFQFPNTWLHVDNIEGEWSAFNEIIKRKDTAIQTQV 1239
            ||||||:.:..::||||::|..||:||:||||||.:||::|||||||.|||:|::|||:|||.||
Mouse  1170 YVQSLKRKIKQFEKQVELYRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQV 1234

  Fly  1240 ASLQAKIVAEDKAVETRTVDFLNDWEKTKPTGGKIRPDDALQQLQIFESKYSRLKEERDNVVKAK 1304
            |:||.|||.||:|||:||.|.|.|||||||..|.:||::|||.|.|:|.|:.|||::|:...|||
Mouse  1235 ANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAK 1299

  Fly  1305 EALELQESAVPNNSAERMNVALEELQDLRGVWSELSKVWTQIDETREKPWLSVQPRKLRQQLEAM 1369
            |||||.::.:.:.|.||:.|||||||||:||||||||||.|||:.:|:||:|||||||||.|:.:
Mouse  1300 EALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDGL 1364

  Fly  1370 MAQLKELPARLRMYESYEYVKKLIQSYIKVNMLIVELKSDALKERHWKQLTKQLRVNWVLSDLSL 1434
            :.|||..|||||.|.|||:|::|::.|:|:|||::||||:|||:||||||.|:|.||||:|:|:|
Mouse  1365 LNQLKNFPARLRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTL 1429

  Fly  1435 GQVWDVNLQKNEGIVKDIILVAQGEMALEEFLKQVRESWQNYELDLINYQNKCRIIRGWDDLFNK 1499
            ||:|||:|||||.:|||::|||||||||||||||:||.|..|||||:|||||||:||||||||||
Mouse  1430 GQIWDVDLQKNEAVVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNK 1494

  Fly  1500 VKEHINSVAAMKLSPYYKVFEEEALTWEEKLNRINALFDVWIDVQRRWVYLEGIFSGSADIKTLL 1564
            ||||||||:|||||||||||||:||:||:|||||.||||||||||||||||||||:||||||.||
Mouse  1495 VKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLL 1559

  Fly  1565 PVETSRFQSISSEFLGLMKKVTKSPKVMDVLNIPAVQRSLERLADLLGKIQKALGEYLERERTSF 1629
            ||||.||||||:|||.|||||:|||.|||||||..|||||||||||||||||||||||||||:||
Mouse  1560 PVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSF 1624

  Fly  1630 PRFYFVGDEDLLEIIGNSKNIARLQKHFKKMFAGVAAILLNEENNVILGISSREGEEVHFMNPVS 1694
            ||||||||||||||||||||:|:||||||||||||::|:|||:|:|:|||||||||||.|..|||
Mouse  1625 PRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVS 1689

  Fly  1695 TVEHPKINEWLSLVEKQMRFTLASLLAQAVQDIKQFRDGK---IDPQAYMEWCDKYQAQIVVLAA 1756
            ..|||||||||:||||:||.|||.|||::|.:::.|  ||   |||..|:.|.||||||:|||:|
Mouse  1690 ITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIF--GKATSIDPNTYITWIDKYQAQLVVLSA 1752

  Fly  1757 QILWSEDVESALQQASENNQSKPMQRVLGNVESTLNVLADSVLQEQPPLRRRKLEHLINEFVHKR 1821
            ||.|||:||:||..........|:|.||.|||.||||||||||.||||||||||||||.|.||:|
Mouse  1753 QIAWSENVENALSNVGGGGDVGPLQSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQR 1817

  Fly  1822 TVTRRLLNNGVTSPKSFQWLCEMRFYFDPRQTEVLQQLTIHMANARFFYGFEYLGVQDRLVQTPL 1886
            .|||.|:.:.:.:.|||:||.:|||||||:||:|||||:|.||||:|.||||||||||:||||||
Mouse  1818 DVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPL 1882

  Fly  1887 TDRCYLTMTQALESRLGGSPFGPAGTGKTESVKALGNQLGRFVLVFNCDETFDFQAMGRIFVGLC 1951
            |||||||||||||:||||||||||||||||||||||:||||||||||||||||||||||||||||
Mouse  1883 TDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLC 1947

  Fly  1952 QVGAWGCFDEFNRLEERMLSACSQQIQTIQEALKYEMDSNKES----ITVELVGKQVRVSPDMAI 2012
            |||||||||||||||||||||.|||:|.|||||:...:.|.:.    ||.||:.|||:|||||||
Mouse  1948 QVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAI 2012

  Fly  2013 FITMNPGYAGRSNLPDNLKKLFRSLAMTTPDRQLIAEVMLFSQGFRSAEKLACKIVPFFKLCDEQ 2077
            ||||||||||||||||||||||||||||.|||||||:|||:|||||:||.||.||||||||||||
Mouse  2013 FITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQ 2077

  Fly  2078 LSNQSHYDFGLRALKSVLISAGNVKRDRIMKIKEQMKQRGDENIDEASVAENLPEQEILIQSVCE 2142
            ||:|||||||||||||||:|||||||:||.|||.:.::|| |.:||..:||||||||||||||||
Mouse  2078 LSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERG-EAVDEGEIAENLPEQEILIQSVCE 2141

  Fly  2143 TMVPKLVAEDIPLLFSLLSDVFPNVGYTRAEMKGLKEEIRKVCQEDYLVCGEGDEQGAAWMEKGL 2207
            |||||||||||||||||||||||.|.|.|.||..|:||::|||||.||..|:|:|         :
Mouse  2142 TMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEE---------V 2197

  Fly  2208 GSTWVDKVLQLYQISNLNHGLMMVGPSGSGKSTAWKTLLKALERFEGVEGVAHVIDPKAISKEAL 2272
            |..||:||||||||:.:|||||||||||||||.||:.|||||||.||||||||:||||||||:.|
Mouse  2198 GGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHL 2262

  Fly  2273 YGVLDPNTREWTDGLFTHILRKIIDNVRGEINKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPN 2337
            ||.|||||||||||||||:|||||||||||:.|||||:|||||||||||||||||||||||||||
Mouse  2263 YGTLDPNTREWTDGLFTHVLRKIIDNVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPN 2327

  Fly  2338 GERLSLPPNVRVMFEVQDLKFATLATVSRCGMVWFSEDVLSTEMIFENYLSRLRSIPLEDGDEDF 2402
            |||||||||||:||||||||:|||||||||||||||||||||:|||.|:|:|||||||::|:::.
Mouse  2328 GERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEA 2392

  Fly  2403 VGVIKPAKDK-EEEVSPSLQVQRDIALLLLPFFSADGIVVRTLEYAMDQEHIMDFTRLRALSSLF 2466
            ....|..:|: ||..||.||:|||.|.::.|:|:::|:|.:.||:|...|||||.||||.|.|||
Mouse  2393 QRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFKLEHIMDLTRLRCLGSLF 2457

  Fly  2467 SMLNQAARNVLTFNAQHPDFPCSADQLEHYIPKALVYSVLWSFAGDAKLKVRIDLGDFVRSVTTV 2531
            |||:||.|||..:||.|||||...:|||.||.:.|||::|||.:||::||:|.:||:::|.:|||
Mouse  2458 SMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTV 2522

  Fly  2532 PLPGAAGAPIIDYEVNMSGDWVPWSNKVPVIEVETHKVASPDIVVPTLDTVRHESLLYTWLAEHK 2596
            |||.|...|||||||::||:|.||..|||.|||||||||:||:|||||||||||:||||||||||
Mouse  2523 PLPTAPNVPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHK 2587

  Fly  2597 PLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRKTPNGVVLSPVQ 2661
            |||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||:|||
Mouse  2588 PLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQ 2652

  Fly  2662 IGKWLVLFCDEINLPDMDSYGTQRVISFLRQLVEHKGFYRASDQAWVSLERIQFVGACNPPTDPG 2726
            :|||||||||||||||||.|||||||||:||:|||.||||.|||.||.|||||||||||||||||
Mouse  2653 LGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPG 2717

  Fly  2727 RKPLSHRFLRHVPIIYVDYPGETSLKQIYGTFSRAMLRLMPALRGYAEPLTNAMVEFYLASQDRF 2791
            |||||||||||||::||||||..||.||||||:||||||:|:||.||||||.||||||..||:||
Mouse  2718 RKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERF 2782

  Fly  2792 TQDMQPHYVYSPREMTRWVRGICEAIRPLDSLPVEGLVRLWAHEALRLFQDRLVDDSERRWTNEN 2856
            |||.||||:|||||||||||||.||:|||::||||||:|:||||||||||||||:|.|||||:||
Mouse  2783 TQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDEN 2847

  Fly  2857 IDLVGQKHFPGINQEEALQRPILYSNWLSKDYMPVNREELREYVHARLKVFYEEELDVPLVLFDE 2921
            ||:|..||||.|::|:|:.|||||||||||||:||::||||:||.||||||||||||||||||:|
Mouse  2848 IDMVALKHFPNIDKEKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNE 2912

  Fly  2922 VLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSIFQIKVHNKYTSEDFDEDLRCV 2986
            |||||||||||||||||||||||||||||||||||||||||||::|||||.|||.||||||||.|
Mouse  2913 VLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTV 2977

  Fly  2987 LRRSGCKDEKIAFILDESNVLDSGFLERMNTLLANGEVPGLFEGDEYTTLMTQCKEGAQREGLML 3051
            |||||||:||||||:||||||||||||||||||||||||||||||||.|||||||||||:|||||
Mouse  2978 LRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLML 3042

  Fly  3052 DSSDELYKWFTQQVMRNLHVVFTMNPSTDGLKDRAATSPALFNRCVLNWFGDWSDSALFQVGKEF 3116
            ||.:|||||||.||:||||||||||||::|||||||||||||||||||||||||..||:||||||
Mouse  3043 DSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEF 3107

  Fly  3117 TTRVDLEKPNWHAPDFFPSVCPLVPANPTHRDAVINSCVYVHQTLHQANARLAKRGGRTMAVTPR 3181
            |:::||||||:..||:.|.|...:|..||||:|::||||:|||||||||||||||||||||:|||
Mouse  3108 TSKMDLEKPNYIVPDYMPVVYDKLPQPPTHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPR 3172

  Fly  3182 HYLDFIHHFVKLYNEKRSDLEEQQLHLNVGLNKIAETVEQVEEMQKSLAVKKQELQAKNEAANAK 3246
            ||||||:|:..|::||||:|||||:||||||.||.|||:||||:::.|.:|.|||:.||.|||.|
Mouse  3173 HYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDK 3237

  Fly  3247 LKQMFQDQQEAEKKKIQSQEIQIRLADQTVKIEEKRKYVMADLAQVEPAVIDAQAAVKSIRKQQL 3311
            ||:|.:|||||||||:.|||||.:|..|...|.:|:..|..||.:||||||:||.|||||:||.|
Mouse  3238 LKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHL 3302

  Fly  3312 VEVRTMANPPSVVKLALESICLLLGENATDWKSIRAVIMRENFINSIVSNFGTENITDDVREKMK 3376
            ||||:|||||:.||||||||||||||:.||||.||::|||||||.:|| ||..|.|:|.:|||||
Mouse  3303 VEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIV-NFSAEEISDAIREKMK 3366

  Fly  3377 SKYLSNPDYNFEKVNRASMACGPMVKWAIAQIEYADMLKRVEPLREELRSLEEQADVNLASAKET 3441
            ..|:|||.||:|.|||||:||||||||||||:.||||||||||||.||:.||:.|..|...|.|.
Mouse  3367 KNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEV 3431

  Fly  3442 KDLVEQLERSIAAYKEEYAQLISQAQAIKTDLENVQAKVDRSIALLKSLNIERERWESTSETFKS 3506
            :.::..||.|||.||||||.|||:|||||.||..|:|||:||.||||||:.||||||.||||||:
Mouse  3432 EQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKN 3496

  Fly  3507 QMSTIIGDVLLSAAFIAYGGYFDQHYRLNLFTTWSQHLQAASIQYRADIARTEYLSNPDERLRWQ 3571
            |||||.||.|||||||||.|||||..|.|||||||.|||.|:||:|.||||||||||.|||||||
Mouse  3497 QMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQ 3561

  Fly  3572 ANALPTDDLCTENAIMLKRFNRYPLIIDPSGQATTFLLNEYAGKKITKTSFLDDSFRKNLESALR 3636
            |::||.||||||||||||||||||||||||||||.|::|||..:|||:||||||:||||||||||
Mouse  3562 ASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALR 3626

  Fly  3637 FGNPLLVQDVENYDPILNPVLNRELRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDIC 3701
            |||||||||||:|||:||||||||:||||||||||||||||||||||||||||||||||||||:|
Mouse  3627 FGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLC 3691

  Fly  3702 SRVTFVNFTVTRSSLQSQCLNQVLKAERPDIDEKRSDLLKLQGEFRLRLRQLEKSLLQALNDAKG 3766
            |||||||||||||||||||||:||||||||:||||||||||||||:|||||||||||||||:.||
Mouse  3692 SRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKG 3756

  Fly  3767 KILDDDSVITTLETLKKEAYDINQKVDETDKVIAEIETVSQQYLPLSVACSNIYFTMDSLNQVHF 3831
            :|||||::|||||.||:||.::.:||:|||.|:.|:|||||||||||.|||:|||||:||.||||
Mouse  3757 RILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQVHF 3821

  Fly  3832 LYQYSLKMFLDIFSTVLYNNPKLEGRTDHSERLGIVTRDLFQVCYERVARGMIHIDRLTFALLMC 3896
            ||||||:.||||:..|||.||.|:|.|||::||.|:|:|||||.:.||||||:|.|.:|||:|:.
Mouse  3822 LYQYSLQFFLDIYHNVLYENPNLKGATDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLA 3886

  Fly  3897 KIHLKGT-SESNLDAEFNFFLRSREGLL-ANPTP-VEGLSAEQIESVNRLALRLPIFRKLLEKVR 3958
            :|.|||| .|...||||..|||.:|.:| |..|| ::||:.||.|:|.||:. ||.|:.|:.||:
Mouse  3887 RIKLKGTVGEPTYDAEFQHFLRGKEIVLSAGSTPKIQGLTVEQAEAVVRLSC-LPAFKDLIAKVQ 3950

  Fly  3959 SIPELGAWLQQSSPEQVVPQLWDESKALSPIASSVHQLLLIQAFRPDRVIAAAHNVVNTVLGEDF 4023
            :..:.|.||..|||||.||.||.|....:||..::|:|||||||||||::|.||..|:|.|||.|
Mouse  3951 ADEQFGIWLDSSSPEQTVPYLWSEETPTTPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESF 4015

  Fly  4024 MPNAEQELDFTSVVDKQLNCNTPALLCSVPGFDASGRVDDLAAEQNKQISSIAIGSAEGFNQAER 4088
            |...||.||.|.:|..::..|||.|:|||||:||||.|:|||||||.||:|||||||||||||::
Mouse  4016 MSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADK 4080

  Fly  4089 AINMACKTGRWVLLKNVHLAPQWLVQLEKKMHSLQPHSGFRLFLTMEINPKVPVNLLRAGRIFVF 4153
            |||.|.|:||||:||||||||.||:|||||:||||||:.||||||||||||||||||||||||||
Mouse  4081 AINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVF 4145

  Fly  4154 EPPPGIRANLLRTFSTVPAARMMKTPSERARLYFLLAWFHAIVQERLRYVPLGWAKKYEFNESDL 4218
            |||||::||:|||||::|.:|:.|:|:|||||||||||||||:||||||.||||:|||||.||||
Mouse  4146 EPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDL 4210

  Fly  4219 RVACDTLDTWIDTTAMGRTNLPPEKVPWDALVTLLSQSIYGGKIDNDFDQRLLTSFLKKLFTARS 4283
            |.||||:|||:|.||.||.|:.|:|:||.||.||::||||||::||:||||||.:||::|||.||
Mouse  4211 RSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRS 4275

  Fly  4284 FEADFALVANVDGASGGLRHITMPDGTRRDHFLKWIENLTDRQTPSWLGLPNNAEKVLLTTRGTD 4348
            |:::|.|...|||.    :.|.||||.||:.|::|:|.|.|.|||||||||||||:|||||:|.|
Mouse  4276 FDSEFKLACKVDGH----KDIQMPDGIRREEFVQWVELLPDAQTPSWLGLPNNAERVLLTTQGVD 4336

  Fly  4349 LVSKLLKMQQLEDDDELAYSVEDQSEQSAVGRGEDGRPSWMKTLHNSATAWLELLPKNLQVLKRT 4413
            ::||:||||.|||:|:|||:  :..:::......||||:||:|||.:|:.||.|:|:.|..||||
Mouse  4337 MISKMLKMQMLEDEDDLAYA--ETEKKARTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSPLKRT 4399

  Fly  4414 VENIKDPLYRYFEREVTSGSRLLQTVILDLQDVVLICQGEKKQTNHHRSMLSELVRGIIPKGWKR 4478
            ||||||||:|:|||||..|::|||.|..||.|||.:|:|:|||||:.|::::|||:||:|:.|..
Mouse  4400 VENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSH 4464

  Fly  4479 YTVPAGCTVIQWITDFSNRVQQLQKVSQLVSQAGAKELQGFPVWLGGLLNPEAYITATRQCVAQA 4543
            ||||||.|||||::|||.|::|||.:||..:..|||||:...|.||||..||||||||||.||||
Mouse  4465 YTVPAGMTVIQWVSDFSERIKQLQNISQAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQA 4529

  Fly  4544 NSWSLEELALDVTITDAGLKNDQKDCCFGVTGLKLQGAQCKNNELLLASTIMMDLPVTILKWIK- 4607
            ||||||||.|:|.:| |........|.|||||||||||.|.||:|.|::.|...||:|.|:|:|
Mouse  4530 NSWSLEELCLEVNVT-ASQSATLDACSFGVTGLKLQGATCSNNKLSLSNAISTVLPLTQLRWVKQ 4593

  Fly  4608 ISSEPRISKLTLPVYLNSTRTELLFTVDLAVAAGQESHSFYERGVAVL 4655
            .|:|.:.|.:|||||||.||.:|:||||..:|..::..||||||||||
Mouse  4594 TSAEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVL 4641

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhc64C	NP_001261432.1	DHC_N1	240..839	CDD:285571	460/605 (76%)
		DYN1	1022..4338	CDD:227570	2468/3330 (74%)
		DHC_N2	1326..1724	CDD:285579	317/397 (80%)
		P-loop_NTPase	1870..2103	CDD:304359	205/236 (87%)
		P-loop_NTPase	2227..2367	CDD:304359	125/139 (90%)
		P-loop_NTPase	2572..2835	CDD:304359	229/262 (87%)
		Cas4_I-A_I-B_I-C_I-D_II-B	2834..>2943	CDD:294426	90/108 (83%)
		P-loop_NTPase	2916..3194	CDD:304359	234/277 (84%)
		MT	3208..3544	CDD:289543	231/335 (69%)
		AAA_9	3569..3784	CDD:289547	190/214 (89%)
		Dynein_heavy	3925..4636	CDD:281078	449/712 (63%)
Dync1h1	NP_084514.2	Stem. /evidence=ECO:0000250	2..1865		1273/1866 (68%)
		DHC_N1	238..830	CDD:285571	460/605 (76%)
		Interaction with DYNC1I2. /evidence=ECO:0000250	446..701		193/255 (76%)
		Interaction with DYNC1LI2. /evidence=ECO:0000250	649..800		113/163 (69%)
		DYN1	1044..4327	CDD:227570	2457/3300 (74%)
		DHC_N2	1321..1719	CDD:285579	317/397 (80%)
		P-loop_NTPase	1866..2103	CDD:304359	205/236 (87%)
		AAA 1. /evidence=ECO:0000250	1866..2097		200/230 (87%)
		AAA 2. /evidence=ECO:0000250	2178..2450		202/280 (72%)
		P-loop_NTPase	2217..2357	CDD:304359	125/139 (90%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2388..2408		5/19 (26%)
		AAA 3. /evidence=ECO:0000250	2554..2803		220/248 (89%)
		P-loop_NTPase	2565..2826	CDD:304359	227/260 (87%)
		AAA 4. /evidence=ECO:0000250	2897..3166		230/268 (86%)
		P-loop_NTPase	2907..3185	CDD:304359	234/277 (84%)
		Stalk. /evidence=ECO:0000250	3187..3498		212/311 (68%)
		MT	3199..3530	CDD:289543	228/331 (69%)
		AAA 5. /evidence=ECO:0000250	3551..3780		199/228 (87%)
		AAA_9	3559..3774	CDD:289547	190/214 (89%)
		Dynein_heavy	3920..4630	CDD:281078	450/717 (63%)
		AAA 6. /evidence=ECO:0000250	4003..4219		162/215 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843014
Domainoid	1	1.000	923	1.000	Domainoid score	I41
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1053
Inparanoid	1	1.050	5433	1.000	Inparanoid score	I1
Isobase	1	0.950	-	0	Normalized mean entropy	S958
OMA	1	1.010	-	-		QHG54007
OrthoDB	1	1.010	-	-		D26380at2759
OrthoFinder	1	1.000	-	-		FOG0005527
OrthoInspector	1	1.000	-	-		oto93016
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	1	1.100	-	-	LDO	PTHR10676
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R359
SonicParanoid	1	1.000	-	-		X3378
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750