DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhc64C and Dnah8

DIOPT Version :9

Sequence 1:	NP_001261432.1	Gene:	Dhc64C / 38580	FlyBaseID:	FBgn0261797	Length:	4661	Species:	Drosophila melanogaster
Sequence 2:	XP_036016186.1	Gene:	Dnah8 / 13417	MGIID:	107714	Length:	4764	Species:	Mus musculus

Alignment Length:	5110	Identity:	1284/5110 - (25%)
Similarity:	2263/5110 - (44%)	Gaps:	884/5110 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SLENPDTSVDPIVNLSIANYDAFANYLRKAVTILLPEDDV----------VPASLNDALDDPVNQ 58
            |.:.|.|||....:|..::.:           :.||||:.          .|......|.|.::|
Mouse    77 SEQGPATSVTDYRSLIPSDEE-----------VTLPEDEESGQARVRARHTPRPAQSVLSDGISQ 130

  Fly    59 DTIR--KFLSD----PQVQALYVQRNCIKEDDSEQPAEGEDEKEQV------TYQISNDVHFTNS 111
            .:.|  ||...    |.:|      ..:||..:......|:.|.::      .:::..:
Mouse   131 SSRRPSKFRRSMTGIPNLQ------ETLKEKQARFREARENRKMKIGPSHKYIFEVLGE------ 183

  Fly   112 RMASLACIKRGL----VVEADKSIHSQLRLINFSDGSPYETLHAFISKSLAPYFKSYVKESGR-- 170
                    |.||    |.|......|.....:|.:....:||.....:...|.|     |.||
Mouse   184 --------KLGLDLVTVEELILDCPSLDPFTSFFEKGGCKTLKFLYQEGEVPGF-----ECGRTI 235

  Fly   171 --ADRDG-------DKMAPSVEKKLA--------------------------ELEMGLL----HL 196
              ..:.|       |..||...|.|.                          :...|||    |:
Mouse   236 TGVPKGGKMMRIYVDNAAPDKLKGLCLFFVRCRNDVAINSKTIHEDVLFSFLDASKGLLEGIKHM 300

  Fly   197 QQNIDIPEITLTAHQTVNNVIRKCAEENR---------KAKVADFGDKVEDSSFLNLLQNGVNRW 252
            .::|.:|.|..|::....|..::...|..         .|.:.|....:|.:..|..:.|.....
Mouse   301 LKSIFLPAILATSNWGALNQSKQGESEKHIFIETIHRYLASLDDATISIEGTVMLKKVDNIDFSK 365

  Fly   253 IAEIKKVTKLNRDPGSGTALQEI--SFWLNLERALYRIQEKRESPEVALTLDILKHGKRFHATVS 315
            :...::||...........|:|:  .::..:|:.|...::.|:..:.:..|..|:|.||..|..:
Mouse   366 LHTFEEVTAAASSSEMVHQLEEVLMVWYKQIEQVLIESEQMRKEADDSGPLTELEHWKRMSAKFN 430

  Fly   316 FDTDTGLK----QALATVAD--YNPLMK-----DFPINDLLSATE----------LEKIRPAVQQ 359
            |..:. :|    :|:..|.:  ::.|:|     |..|.|  ||.|          |||:   .|.
Mouse   431 FIIEQ-IKGSNCKAVINVLNVAHSKLLKNWRDLDARITD--SANESKDNVRYLYTLEKV---CQP 489

  Fly   360 IF-------AHLRKVRNTKYPIQRCLKLIEAISR--DLSQQLLKVLGTRRLMHIPFDEFERVMNQ 415
            ::       ||  .::|    :...:::|.::||  :.|:::..:             |.:|.||
Mouse   490 LYNYDLVSMAH--GIQN----LINAIRMIHSVSRYYNTSERMTSL-------------FIKVTNQ 535

  Fly   416 CFEIFSC------------WDDEYDKLQGLLRDIV----------KKKRDEHLKMVWRVSPAHKK 458
            .  :.:|            ||.|...:...::|.:          .|.|.:.|:     |...|.
Mouse   536 M--VTACKAYITDGGTNHVWDQETPAVLKKIQDCIFLFKEYQASFHKTRKQILE-----SSGEKS 593

  Fly   459 LQ-TRMEHMRKFRRQHEQLRTVILRVLRPTKPAVGDDGNVVETKQPYS---LDAADANAIEEVNL 519
            .: :.|....||....::|..:...:            .:|:|....|   ::..|...|:..|:
Mouse   594 FEVSEMYIFGKFEAFCKRLEKITEMI------------TIVQTYSALSNSTIEGIDILGIKFKNI 646

  Fly   520 AYENVK--EVDCLDITKEGSEAWEAAVKRYEEKIDRVETRIT---AHL--RDQLGTAKNANEMFR 577
             |:.:|  :.|.||..:   ..::.....:..||:.:|:|.|   .||  :|.:...| |..:.:
Mouse   647 -YQGIKKNQYDILDPRR---TEFDTDFTEFMGKINILESRPTPTSPHLLKQDYIYLNK-ATPLKQ 706

  Fly   578 IFSRFNALFVRPHIR---GAIREYQ--TQLIQR------------VKDDIEALHEKFKVQYPQSK 625
            ..:.:|.:.::..:.   |.|...|  .||:||            :...||.:.:.:..:...:|
Mouse   707 DHTYYNQIQIQAFMNSTFGKILSSQQALQLLQRFQKLNIPCLHLEINHTIERILQCYVAELEFTK 771

  Fly   626 SCRLSS------VRDLPPVAGSIIWARQI---DNQLTMYLKRVEDVLGKGWETHIEGQKLKADGD 681
            ...||.      .|::||:||.|:|.||:   .|:...|..:..|:|     :..||:.:....:
Mouse   772 KLYLSQKDDPPLARNMPPIAGKILWVRQLFRRINEPINYFFKNSDIL-----SSTEGKAVIRQYN 831

  Fly   682 SFRAKLSISDV-FH-EWARKVQERNFGSTGRIFTIESTRSRIGRGNVLRLRVNFLPEIITLAKEV 744
            .....|...:| :| .|.::|.:..:.....:|        :......:|.|||.|:|:.:.:|.
Mouse   832 RIAYVLVEFEVAYHTAWFKEVSQLQYALQATLF--------VRHPETGKLLVNFDPKILEVVRET 888

  Fly   745 RNIKNLGFRVP------LTIVNKAHQANQIYPYAISLIESVRTYERTLEKLNNRSLAQNSVFKIE 803
            :.:..:...||      |.:.:|. :|:::|...:     ::.|:...:::       .|||
Mouse   889 KCMIKMKLDVPEQAKNLLKLESKL-KADKLYLQGL-----LQYYDDLCQEV-------PSVF--- 937

  Fly   804 DRASIVPLVAGLRKDVLNLVSEGIG-LIWESYKLDPYVIRLSECVTQFQE---KVDDLLVVEEQL 864
                 |.|:....|.|.:::.:|:. |.|.|..|:.:...:...:..|.:   ||:||  .|..:
Mouse   938 -----VNLMTPKMKKVESVLRQGLTVLTWSSLMLESFFKEVESVLDMFNQLLKKVNDL--CEMHI 995

  Fly   865 DVDVRSLETCPYSAATFVEILS-----KIQHAVDDLSL-----RQYSNLSVWVTRLDEEVEKKLA 919
            |..::.:      |.|.:..||     |::   |.|:|     ::.:::....:|..||..|:|.
Mouse   996 DTVLKEI------AKTLLISLSDSGTTKVE---DMLTLNETYTKECADILNHKSRHVEEAVKELI 1051

  Fly   920 L-----------------------RLQAGIQA-WTEAL--TGNKKEVDTSMDTDA---------- 948
            |                       |:..|.:| .||.|  .....||||:...|.
Mouse  1052 LIFEQIYEVKYTGKAAKSVKEQRKRVVFGSEAEETEGLDFESTTMEVDTNDKEDEFKKECKEVYA 1116

  Fly   949 --------PAQPTHKLGGDPQ--------------------IQNAVHEIRITNQQMYLYPSIEEA 985
                    ..|...:|..|..                    |:..|| :.|.|  :.:.||:::.
Mouse  1117 FFSHQLLDSLQKATRLSLDTMKRRIFVGSQGRRRSEDIVSFIKTEVH-LAIPN--VVMVPSLDDI 1178

  Fly   986 R----------FQIMQQFFAW-----QAIVTSQVRLQSTRYQVGLEKHVSQTYRNLLTKLPEGKI 1035
            :          .::.:....|     :.|.:.|...:.:.......|.:.:..|:....:|..|
Mouse  1179 QQAINRMIQLTLEVSRGVAHWGQQQVRQIKSFQNNSRGSDQPPASGKPLKKEERSFEETIPARK- 1242

  Fly  1036 LENAY-GAIEQK------------VSEVRNYVDEWL----RYQSLWDLQADMLYGRLGEDVNLWI 1083
            |:|.| |..|.|            |:.:|....|.|    :|::||.           ||.::.:
Mouse  1243 LKNFYPGVAEHKDISKLVLLLSSSVNSLRKAATEALQDFQKYKTLWI-----------EDRHVKV 1296

  Fly  1084 K-------CLNDIKQSRTTFDTSDTR-RAYGPIII------DYAKVQAKVTLKYDSW-------- 1126
            |       .|.:|:.....:.|.:.. :...|||:      ....::..::::..:|
Mouse  1297 KEFLANNPSLTEIRSEILHYATLEQEIKELKPIIVVGSLELHTEPMKLALSIEAKAWKMLLCRYL 1361

  Fly  1127 HKEALGKFGTLLGTEMTSFHSKVSKSRTDLEMQSIEAASTSDAVSFITYVQSLKKDMIAWDKQVE 1191
            ::|...|...:: |.:..:..|:|:...||:    :.....:|:|.|      :.:.|..|..:.
Mouse  1362 NEEYKKKMSDMI-TFINEYLKKLSRPIRDLD----DVRFAMEALSCI------RDNEIQMDMTLG 1415

  Fly  1192 VFREAQRILERQRFQFPNTWLHVDNIEGEWSAFNEIIKRKDTAIQTQVASLQ----------AKI 1246
            ...||..||  .||:...|....:.::....:||: ::.|..::|.::..:|          .|:
Mouse  1416 PIEEAYGIL--NRFEVKVTKEESEGVDTLRYSFNK-LQSKAVSVQGELVKVQPKFKSNLLESVKV 1477

  Fly  1247 VAEDKAVETRTVDFLNDWEKTKPTGGKIRPDDALQQLQIFESKYSRLKEERDNVVKAKEALELQE 1311
            ..||      .::|...:|...|....|.|.:|..:||||::.:..|..:.......::...|
Mouse  1478 FCED------VINFTEAYETEGPMVPNIPPQEASNRLQIFQANFDDLWRKFVTYSSGEQLFGL-- 1534

  Fly  1312 SAVPNNSAERMNVALEELQDLRGVWSELSKVWTQIDETREKPWLSVQPRKLRQQLEAMMAQLKEL 1376
               |....|.::...:||..|:.::.....|...|....|..|..|...|:..:|:....:.::|
Mouse  1535 ---PVTDYEVLHKTRKELNLLQKLYGLYDTVMGSISGYYEILWGDVDIEKINAELQEFQNRCRKL 1596

  Fly  1377 PARLRMYESYEYVKKLIQSYIKVNMLIVELKSDALKERHWKQLTKQLRVNW-VLSD-LSLGQVWD 1439
            |..|:.::::..:||.|..:.:...|:..:.:.|:|:|||.::::.....: |.|| ..|..:.:
Mouse  1597 PRALKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDTFCLRNIME 1661

  Fly  1440 VNLQKNEGIVKDIILVAQGEMALEEFLKQVRESWQNYELDLINYQNKCR-IIRGWD--DLFNKVK 1501
            ..|.||:..::||.:.|..|..:|..|.||.|:|....|....::.|.. :::|.:  ::...::
Mouse  1662 APLLKNKDDIEDICISAIKEKDIEAKLTQVIENWTYQNLSFAAFKGKGELLLKGTESGEIITLME 1726

  Fly  1502 EHINSVAAMKLSPYYKVFEEEALTWEEKLNRINALFDVWIDVQRRWVYLEGIFSGSADIKTLLPV 1566
            :.:..:.::..:.|...|::....|..||:..:.:.:.|:.||..|||||.:|.| .||...||.
Mouse  1727 DSLMVLGSLLSNRYNTPFKKNIQNWVFKLSTSSDIIEEWLIVQNLWVYLEAVFVG-GDIAKQLPQ 1790

  Fly  1567 ETSRFQSISSEFLGLMKKVTKSPKVMD-VLNIPAVQRSLERLADLLGKIQKALGEYLERERTSFP 1630
            |..|||:|...::.:|::..::|.|:. .:....:.:.|..|.:.|...||:|..|||::|..||
Mouse  1791 EAKRFQNIDKSWIKIMQRAHENPNVISCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFP 1855

  Fly  1631 RFYFVGDEDLLEIIGNSKNIARLQKHFKKMFAGVAAILLN-EENNVILGISSREGEEVHFMNPVS 1694
            ||:||.|..||||:|.:.:...:|.|...:...:..:..: ::.:.:..:.|||||::....||
Mouse  1856 RFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRMTAVISREGEKIMLDTPV- 1919

  Fly  1695 TVEHPKINEW-LSLVEKQMRFTLASLLAQAVQDIKQFRDGKIDPQAYMEWCDKYQAQIVVLAAQI 1758
             :....:..| |.|::.||. :|.:::..|...|..  .|.:    .:.:.:.:.||:.:|..|:
Mouse  1920 -MAKGPVEIWLLDLLKVQMS-SLHNIIRSAFYQISD--SGFL----LLPFLNHFPAQVGLLGIQM 1976

  Fly  1759 LWSEDVESALQQASENNQSKPMQRVLGNVESTLNVLADSVLQEQPPLRRRKLEHLINEFVHKRTV 1823
            ||:.|.|.||..|.::.  |.||.........||.|......:.....|.|.|.||...||:|.:
Mouse  1977 LWTHDSEEALNNAKDDR--KIMQITNQKFLDILNTLISQTTHDLTKFDRVKFETLITIHVHQRDI 2039

  Fly  1824 TRRLLNNGVTSPKSFQWLCEMRFYFDPRQTEVLQQLTIHMANARFFYGFEYLGVQDRLVQTPLTD 1888
            ...|:...:.|...|:||.:.||||    .|.|.|..:.:.:..|.|..|:||..||||.|||||
Mouse  2040 FDDLVKMHIKSVTDFEWLKQSRFYF----KEDLDQTVVSITDVDFIYQNEFLGCTDRLVITPLTD 2100

  Fly  1889 RCYLTMTQALESRLGGSPFGPAGTGKTESVKALGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQV 1953
            |||:|:.|||...:||:|.|||||||||:.|.:|..||::|:||||.:..||:.:||||.||.|.
Mouse  2101 RCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQS 2165

  Fly  1954 GAWGCFDEFNRLEERMLSACSQQIQTIQEALKYEMDSNKESITVELVGKQVRVSPDMAIFITMNP 2018
            |:|||||||||:|..:||..:|||..:..|.|   :..|:.|..:  |..|.::|:..||:||||
Mouse  2166 GSWGCFDEFNRIELPVLSVAAQQIYIVLTARK---ERKKQFIFSD--GDCVDLNPEFGIFLTMNP 2225

  Fly  2019 GYAGRSNLPDNLKKLFRSLAMTTPDRQLIAEVMLFSQGFRSAEKLACKIVPFFKLCDEQLSNQSH 2083
            |||||..||:|||..||::||..||||:|..|.|.|.||.....||.|....:|||:|||:.|.|
Mouse  2226 GYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVH 2290

  Fly  2084 YDFGLRALKSVLISAGNVKRDRIMKIKEQMKQRGDENIDEASVAENLPEQEILIQSVCETMVPKL 2148
            ||||||.:.|||.:.|:.||.|            .|:.:.::|...|.:..:          .||
Mouse  2291 YDFGLRNILSVLRTLGSQKRAR------------PEDSELSTVMRGLRDMNL----------SKL 2333

  Fly  2149 VAEDIPLLFSLLSDVFPNV---GYTRAEMKGLKEEIRKVCQEDYLVCGEGDEQGAAWMEKGL--G 2208
            |.||.||..||::|:||.:   ..|.||::...:....:                    :||  .
Mouse  2334 VDEDEPLFLSLINDLFPGLQLDSSTYAELQSAVDNQVNL--------------------EGLINH 2378

  Fly  2209 STWVDKVLQLYQISNLNHGLMMVGPSGSGKSTAWKTLLKALERFEGVEGVAH---VIDPKAISKE 2270
            ..|..|::|||:.|.:.||||.:|||||||:|....|:|:|...    |..|   .::||||:..
Mouse  2379 PPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKSLTEC----GRPHREMRMNPKAITAP 2439

  Fly  2271 ALYGVLDPNTREWTDGLFTHILRKIIDNVRGEINKRQWIIFDGDVDPEWVENLNSVLDDNKLLTL 2335
            .::|.||..|.:||||:|:.:.||.:...:||   ..::|.||.||..|:|||||||||||.|||
Mouse  2440 QMFGRLDTATNDWTDGIFSTLWRKTLKAKKGE---NIFLILDGPVDAIWIENLNSVLDDNKTLTL 2501

  Fly  2336 PNGERLSLPPNVRVMFEVQDLKFATLATVSRCGMVWFSEDVLSTEMIFENYLSRLRSIPLEDGDE 2400
            .||:|:.:.|..:::|||.:::.|:.|||||.|||:.|...||...|.:.:|.: ||       :
Mouse  2502 ANGDRIPMAPTCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKK-RS-------Q 2558

  Fly  2401 DFVGVIKPAKDKEEE---------VSPSLQVQRDIALLLLPFFSADGIVVRTLEYAMDQEHIMDF 2456
            ....|.....||..|         ::|.:|:                         ::..:||.
Mouse  2559 QEASVFLSLYDKVFEDAYTYMKLSLNPKMQL-------------------------LECNYIMQ- 2597

  Fly  2457 TRLRALSSLFSMLNQAARNVLTFNAQHPDFPCSADQLEHYIPKALVYSVLWSFAGDAKLKVRIDL 2521
             .|..|..|.....:...:             |.|.|.    |..|:.::||.....:|..|..|
Mouse  2598 -SLNLLEGLIPSKEEGGVS-------------SGDHLH----KLFVFGLMWSLGALLELDSREKL 2644

  Fly  2522 GDFVR---SVTTVP-LPGAAGAPIIDYEVNMSGDWVPWSNKVPVIEVETHKVAS-PDIVVPTLDT 2581
            ..|:|   |...:| :|..:...:.::.|...|||..|:.::......|..:.. ..|:||.:|.
Mouse  2645 EVFLRGHGSKLNLPEIPKGSQQTMYEFYVTDYGDWEHWNKRIQPYFYPTDSIPEYSSILVPNVDN 2709

  Fly  2582 VRHESLLYTWLAEHKPLVLCGPPGSGKTMTLFSALRAL-PDMEV-VGLNFSSATTPELLLKTFDH 2644
            :|...|:.|...:||.::|.|..|:.||:.:.:.|:.. |:::: ..|||||||.|.:..:|.:.
Mouse  2710 IRTNFLIDTIAKQHKAVLLTGEQGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEPMMFQRTIES 2774

  Fly  2645 YCEYRKTPNGVVLSPVQIGKWLVLFCDEINLPDMDSYGTQRVISFLRQLVEHKGFYRASDQA-WV 2708
            |.:.|.   |....|.. |:.:.:|.|:||:|.::.:|.|.....:||::|.:|.|...... :.
Mouse  2775 YVDKRM---GSTYGPPG-GRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFT 2835

  Fly  2709 SLERIQFVGACNPPTDPGRKPLSHRFLRHVPIIYVDYPGETSLKQIYGTFSRAMLRLMPALRGYA 2773
            ::..:|.:.|...| ..||..:..|..|...:.....|..||:.:|:|...          .||.
Mouse  2836 TIVDVQLIAAMIHP-GGGRNDIPQRLKRQFTVFNCTLPSNTSIDKIFGIIG----------CGYF 2889

  Fly  2774 EPLTNAMVEF-----YLASQDR----FTQ-DMQP-----HYVYSPREMTR-WVRGICEAIRPLDS 2822
            :|......|.     .|.|..|    :|: .|.|     ||:::.|:::| |...:........|
Mouse  2890 DPCRKFRPEICDMVGNLVSVSRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTVKAEECSS 2954

  Fly  2823 LPVEGLVRLWAHEALRLFQDRLVDDSERRWTN--------ENI------DLVGQKHF-------- 2865
            :|:  |:.|:.||..|:..||.:...:.:|.|        |||      :::.:.:|
Mouse  2955 IPI--LLSLFKHECNRVIADRFITPDDEQWFNSQLIRAVEENISPEVAANILPEPYFVDFLRDMP 3017

  Fly  2866 --PGINQEEAL-QRPILYSNWLSKDYMPVNREELREYVHARLKVFYEEELDVPLVLFDEVLDHVL 2927
              .|...|:.: :.|.:|....|.:::   .|:|:.|.....::.....||  ||.|.:.:.|::
Mouse  3018 EPTGDEPEDTMFEVPKIYELVPSFEFL---SEKLQFYQRQFNEIIRGTSLD--LVFFKDAMTHLV 3077

  Fly  2928 RIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSIFQIKVHNKYTSEDFDEDLRCVLRRSGC 2992
            :|.||.|...|:.||:||.|:||.:||:..:::.|..||||.:...|...:..|||:.:.:.:|.
Mouse  3078 KISRIIRTSCGNALLVGVGGSGKQSLSKLASFIAGYQIFQITLTRSYNVSNLIEDLKNLYKVAGA 3142

  Fly  2993 KDEKIAFILDESNVLDSGFLERMNTLLANGEVPGLF---EGDEYTT-LMTQCKEGAQREGLMLDS 3053
            :.:.|.||..::.:.|..|||.:|.||::||:..||   |.||.|. |::..|....|..   .:
Mouse  3143 EGKGITFIFTDNEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHP---PT 3204

  Fly  3054 SDELYKWFTQQVMRNLHVVFTMNPSTDGLKDRAATSPALFNRCVLNWFGDWSDSALFQVGKEFTT 3118
            .|.||::|..:..:|||||...:|..:..:.|:...|.|.:.|.::||..|...||..|...|..
Mouse  3205 FDNLYEYFITRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPKEALIAVASYFLL 3269

  Fly  3119 RVDLEKPNWHAPDFFPSVCPLVPANPTHRDAVINSCVYVHQTLHQANARLAKRGGRTMAVTPRHY 3183
            ..::             ||.:    .|.|. |:.:....|..:.::.....:|..|...|||:.|
Mouse  3270 DYNI-------------VCSI----ETKRH-VVETMGLFHDMVSESCENYFQRYRRRAHVTPKSY 3316

  Fly  3184 LDFIHHFVKLYNEKRSDLEEQQLHLNVGLNKIAETVEQVEEMQKSLAVKKQELQAKNEAANAKLK 3248
            |.||:.:..:|.:|...:.||...:|:||:|:.|..|.|.::.:.||||::||...:..|:..|.
Mouse  3317 LSFINGYKSIYTDKVKYINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLA 3381

  Fly  3249 QMFQDQQEAEKKKIQSQEIQIRLADQTVKIEEKRKYVMADLAQVEPAVIDAQAAVKSIRKQQLVE 3313
            ::....|.:.|.|.:.||::.:......:|:.::......|...:||:.:|:||:.:|:...:..
Mouse  3382 EVTVSAQASAKVKNEVQEVKDKAQKIVDEIDSEKVKAETKLEAAKPALEEAEAALNTIKPNDIAT 3446

  Fly  3314 VRTMANPPSVVKLALESICLLLGENATD--------------WKSIRAVIMRENFINSIVSNFGT 3364
            ||.:|.||.::...::.: |||.:...|              |.....::....|:.|: ..|..
Mouse  3447 VRKLAKPPHLIMRIMDCV-LLLFQKKIDPVTMDPEKPCCKPSWGESLKLMSATGFLFSL-QQFPK 3509

  Fly  3365 ENITDDVREKMKSKYLSNPDYNFEKVNRASMACG---PMVKWAIAQIEYADMLKRVEPLREELRS 3426
            :.|.::..|.:: .|.:..||.||.   |...||   .::.|.:|.:.:..:.:.|.||:..|..
Mouse  3510 DTINEETVELLQ-PYFNMDDYTFES---AKKVCGNVAGLLSWTLAMVIFYGINREVLPLKANLAK 3570

  Fly  3427 LEEQ---ADVNLASAKETKDLVEQLERSIAAYKEEYAQLISQAQAIKTDLENVQAKVDRSIALLK 3488
            .|.:   |:|.|..|:.   |:::.:..:...:.::...:.:...:..|.:..:.|:..:..|:.
Mouse  3571 QEGRLAVANVELGKAQA---LLDEKQAELDKVQAKFDAAMKEKMDLLNDADMCRKKMQAASTLID 3632

  Fly  3489 SLNIERERWESTSETFKSQMSTIIGDVLLSAAFIAYGGYFDQHYRLNLF-TTWSQHLQAASIQYR 3552
            .|:.|:.||...|:.||:|::.::|||||...|::|.|.|:|.:|..|. ..|...|:|..|.:.
Mouse  3633 GLSGEKVRWTQQSKEFKTQINRLVGDVLLCTGFLSYLGPFNQIFRNYLLKDQWELELKARKIPFT 3697

  Fly  3553 ADIARTEYLSNPDERLRWQANALPTDDLCTENAIMLKRFNRYPLIIDPSGQATTFLLNEYAGKKI 3617
            .::.....|.:|.....|....||.|||..:|.|::.:..||||:|||..|..|::.::.....:
Mouse  3698 ENLNLIAMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDL 3762

  Fly  3618 TKTSFLDDSFRKNLESALRFGNPLLVQDV-ENYDPILNPVLNRELRRTGGRVLITLGDQDIDLSP 3681
            ..||.....||.:||.:|..|.|||::|: |..||.|:.||.:...::|....:.:||::.|:..
Mouse  3763 QVTSLNHKYFRTHLEDSLSLGRPLLIEDIREELDPALDNVLEKNFIKSGTAFKVKVGDKECDIMD 3827

  Fly  3682 SFVIFLSTRDPTVEFPPDICSRVTFVNFTVTRSSLQSQCLNQVLKAERPDIDEKRSDLLKLQGEF 3746
            :|.::::|:.|...|.|:|.::.:.::||||...|::|.|.:|:..|:.:::.:|..||:.....
Mouse  3828 TFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELESERVKLLEDVTFN 3892

  Fly  3747 RLRLRQLEKSLLQALNDAKGKILDDDSVITTLETLKKEAYDINQKVDETDKVIAEIETVSQQYLP 3811
            :.::::||.:||..|:..||.::||:|:|..|...|:.|.::::|:....:...:|.|..:::.|
Mouse  3893 KRKMKELEDNLLYKLSATKGSLVDDESLIGVLRITKQTAAEVSEKLHVAAETEIKINTAQEEFRP 3957

  Fly  3812 LSVACSNIYFTMDSLNQVHFLYQYSLKMFLDIFSTVLYNNPKLEGRTDHS----ERLGIVTRDLF 3872
            .:...|.:||.:..::.|:.:||.||..||.:|...:       .|::.|    :|:..:...|.
Mouse  3958 AATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSM-------ARSEKSPLPQKRITNIIEYLT 4015

  Fly  3873 QVCYERVARGMIHIDRLTFALLM-CKIHL-KGTSESNLDAEFNFFLRSREGL---LANPTPVEGL 3932
            ...:....||:....:..|.||| .||.| :||.:..   ||...::....|   ...|.|...:
Mouse  4016 YEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHK---EFQALIKGGAALDLKACPPKPFRWI 4077

  Fly  3933 SAEQIESVNRLAL-RLPIFRKLLEKVRSIPELG--AWLQQSSP-EQVVPQLWDESKALSPIASSV 3993
            .  .:..:|.:.| :||.|.:::.:: |..|.|  .|..:.:| |:::|..:::|      ..:.
Mouse  4078 L--DMTWLNLVELSKLPQFAEIMNQI-SRNEKGWKNWFDKDAPEEEIIPDGYNDS------LDTC 4133

  Fly  3994 HQLLLIQAFRPDRVIAAAHNVVNTVLGEDFMPNAEQELDFTSVVDKQLNCNTPALLCSVP-GFDA 4057
            .:||||:::.|||.:..|...:...|.|.:.......|:.|.   ::.:.:|| |:|.:. |.|.
Mouse  4134 RKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTW---EESDTHTP-LICFLSMGSDP 4194

  Fly  4058 SGRVDDLAAEQNKQISSIAIGSAEGFNQAERAINMACKTGRWVLLKNVHLAPQWLVQ-LEKKMHS 4121
            :.::|.||.:...:..:|::|..:..: |.:.|.::.:.|.||||:|.||..:::.: ||..|.:
Mouse  4195 TIQIDALAKKLKLECRTISMGQGQEVH-ARKLIQLSMQQGGWVLLQNCHLGLEFMEELLEMLMVT 4258

  Fly  4122 LQPHSGFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGIRANLLRTFSTV--PAARMMKTPSERAR 4184
            ......||:::|.|.:.:.|:.||:....|..|||.|:||.|.|||:.:  ....:...|..:..
Mouse  4259 ETTEDSFRVWITTEPHDRFPITLLQTSIKFTNEPPQGVRAGLKRTFAGINQDLLDISNLPMWKPM 4323

  Fly  4185 LYFLLAWFHAIVQERLRYVPLGWAKKYEFNESDLRVACDTLDTWIDTTAMGRTNLPPEKVPWDAL 4249
            || .:|:.|:.||||.::.||||...||||.:|...:...:...:|...:      .:.|.|..:
Mouse  4324 LY-TVAFLHSTVQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDI------KKGVSWSTV 4381

  Fly  4250 VTLLSQSIYGGKIDNDFDQRLLTSFLKKLFTARSFEADFALVANVDGASGGLRHITMPDGTRRDH 4314
            ..::.:..|||::.:|||:|||..|.:..|:.:.||..|.....          ..:|.....|.
Mouse  4382 RYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEPSFCFYTG----------YKIPICKTLDQ 4436

  Fly  4315 FLKWIENLTDRQTPSWLGLPNNAEKVLLTTRGTDLVSKLLKMQQLEDDDELAYSVEDQSEQSAVG 4379
            :.::|::|.....|...||..||:....:...:|::..:..:               |.::|..|
Mouse  4437 YFEFIQSLPSLDNPEVFGLHPNADITYQSNTASDVLETITNI---------------QPKESGGG 4486

  Fly  4380 RGEDGRPSWMKTLHNSATAWLELLPKNL---QVLKRTVE-------NIKDPLYRYFEREVTSGSR 4434
            .||...    ..::..:...|..||.|.   :|..|.::       ||      :..:|:....:
Mouse  4487 VGETRE----AIVYRLSEDMLSKLPPNYVPHEVKARLMKMGHLNSMNI------FLRQEIDRMQK 4541

  Fly  4435 LLQTVILDLQDVVLICQGEKKQTNHHRSMLSELVRGIIPKGWKRYTVPAGCTVIQWITDFSNRVQ 4499
            ::..:...|.|:.|..:|....:.:.|..|..:....||:.|||.:..:. |:..|.|:...|..
Mouse  4542 VISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVSWDSS-TLGFWFTELLERNA 4605

  Fly  4500 QLQKVSQLVSQAGAKELQGFP--VWLGGLLNPEAYITATRQCVAQAN-SWSLEELALDVTITDAG 4561
            |.   |..:       .:|.|  .|:.|..||:.::||.||.|.:|: .|:|:    .|||.:..
Mouse  4606 QF---STWI-------FEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALD----TVTIHNEV 4656

  Fly  4562 LKNDQKDCC------FGVTGLKLQGAQC-KNNELLLAST---IMMDLPVTILKWIKISSEPRISK 4616
            |:..:::..      ..:.||.:.||.. :.|..|..||   :...|||..:..|. |:.|:..|
Mouse  4657 LRQTKEEIITPPAEGVYIYGLYMDGASWDRRNGKLTESTPKVLFTQLPVLHIFAIN-STAPKDPK 4720

  Fly  4617 L-TLPVYLNSTRTELLFTVDLAVAAGQESHSFYERGVAVL 4655
            | ..|:|....||:|.|...:.:........:..||||:|
Mouse  4721 LYVCPIYKKPRRTDLTFITVVYLRTVLSPDHWILRGVALL 4760

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhc64C	NP_001261432.1	DHC_N1	240..839	CDD:285571	137/698 (20%)
		DYN1	1022..4338	CDD:227570	967/3481 (28%)
		DHC_N2	1326..1724	CDD:285579	106/405 (26%)
		P-loop_NTPase	1870..2103	CDD:304359	124/232 (53%)
		P-loop_NTPase	2227..2367	CDD:304359	65/142 (46%)
		P-loop_NTPase	2572..2835	CDD:304359	73/281 (26%)
		Cas4_I-A_I-B_I-C_I-D_II-B	2834..>2943	CDD:294426	31/133 (23%)
		P-loop_NTPase	2916..3194	CDD:304359	85/281 (30%)
		MT	3208..3544	CDD:289543	87/356 (24%)
		AAA_9	3569..3784	CDD:289547	70/215 (33%)
		Dynein_heavy	3925..4636	CDD:281078	185/742 (25%)
Dnah8	XP_036016186.1	DHC_N1	382..969	CDD:400611	133/669 (20%)
		DYN1	1391..4412	CDD:227570	922/3249 (28%)
		AAA_6	2082..2409	CDD:403853	163/373 (44%)
		Dynein_C	4466..4761	CDD:408026	77/336 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810