DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhc64C and Dnah5

DIOPT Version :9

Sequence 1:	NP_001261432.1	Gene:	Dhc64C / 38580	FlyBaseID:	FBgn0261797	Length:	4661	Species:	Drosophila melanogaster
Sequence 2:	NP_579943.3	Gene:	Dnah5 / 110082	MGIID:	107718	Length:	4621	Species:	Mus musculus

Alignment Length:	5038	Identity:	1279/5038 - (25%)
Similarity:	2214/5038 - (43%)	Gaps:	917/5038 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 LSDPQVQALYVQRNCIKEDD------------------------------SEQPAEGEDEKEQVT 99
            |:.|:|:...::.|.|:..|                              ...||.|:.:|.:|.
Mouse    50 LNKPEVEDALLEGNQIERMDQLFAVGGLRHLMFYYQDVEGAEAGHCGSSGGVNPASGKMKKPKVF 114

  Fly   100 YQISNDVHFTNSRMASLACIKRGLVVEADKS-------IHSQL--RLINFSDGSPYETLHAFISK 155
            .....||....      ||:   ..:.:|.|       ||.::  ..::.:||....::...:|.
Mouse   115 VTEGKDVALMG------ACV---FFIRSDPSKAITPENIHREVSFNTLDTADGGLLNSVRRLLSD 170

  Fly   156 SLAPYFKSYVKESGRADRDGDKMAPSVEKK-LAELE--MGLLHLQQNIDIPEITLTAHQTVNNVI 217
            ...|..::  ...|..:.:|.:.|.|:.:: |:.||  :|:|...||        :..:.||  :
Mouse   171 IFIPALRA--SSHGWGELEGLQDASSIRQEFLSSLEGFVGILSGAQN--------SLKEKVN--L 223

  Fly   218 RKCAEENRKAKVADFGDKVEDSSFLNLLQNG---------VNRWIAEIKKV----TKLNRDPGSG 269
            :||       .:.:.....|.:.:|.|..|.         :..||.:::::    ::|.::....
Mouse   224 QKC-------DIIELKSLKEPTDYLALASNPETVEKVECCMRVWIKQMEQILAENSQLRKEADDV 281

  Fly   270 TALQEISFW-LNLERALYRIQEKRESPEVALTLDILKHGKRFHATVSFDTDTGLKQALATVAD-- 331
            ....|:..| ..|.|..| :.::.:||:|...|.:|...|.....|..|||..:..|.....|
Mouse   282 GPRAELEHWKQRLSRFNY-LLDQLKSPDVKAALALLAAAKSKLLKVWRDTDIRITDAANEAKDNV 345

  Fly   332 ---------YNPLMKDFPINDLLSATELEKIRPAVQQIFAHLRKVRNTKYPIQRCLKLIEAISR- 386
                     .:||....|:      |.::.|...:..|                  |::.:||.
Mouse   346 KYLYTLEKCCDPLYSSDPV------TMIDAIPTLINAI------------------KMVYSISHY 386

  Fly   387 -DLSQQLLKVLGTRRLMHIPFDEFERVMNQCFEIFSC------------WDDEYDKLQGLLRDIV 438
             :.|:::..:             |.:|.||.  |.:|            |....:.:...:..::
Mouse   387 YNTSEKITSL-------------FVKVTNQM--ISACKAHITNNGTATIWSQPQEIVMQKIAAVI 436

  Fly   439 KKKRD-----EHLKMVWRVSPAHKKLQ-TRMEHMRKFRRQHEQLRTVILRVLRPTKPAVGDDGNV 497
            |.|:.     :..|...:.:|:.|:.. :.|....||...|.:|..::               ::
Mouse   437 KLKQGYQSCFQETKQKLKQNPSEKQFDFSEMYIFGKFETFHRRLAKIM---------------DI 486

  Fly   498 VETKQPYS-LDAADANAIEEVNLAYENV------KEVDCLDITK-EGSEAWEAAVKRYEEKIDRV 554
            ..|.:.|| |..:....:|::...|:::      ||.:.||..: :..:.:|...||..|..:.:
Mouse   487 FTTFKTYSVLQDSKIEGLEDMATKYQDIVAAIKKKEYNFLDQREMDFDQDYEEFCKRINELHNDL 551

  Fly   555 ETRITAHLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIEA---LHEK 616
            : |......:::.:.:.|....:.|.|.|.    |:: |...:||. :.|....||:.   |:.|
Mouse   552 Q-RFMDITFEKIPSTRQALSTLKKFERLNI----PNL-GIEEKYQI-IFQNFATDIDTISKLYTK 609

  Fly   617 FKVQYPQSKSCRLSSVRDLPPVAGSIIWARQIDNQLTMYLKRVED---VLGKGWETHIEGQKLKA 678
            .|...|.:        |:.||:||.|:||||:.::|...::..:.   ||    .|......:::
Mouse   610 QKYDPPLA--------RNQPPIAGKILWARQLFHRLEQPMQLFQQHPFVL----RTAEAKPVIRS 662

  Fly   679 DGDSFRAKLSISDVFHE-WARKVQERNFG----------STGRIFTIESTRSRIGRGNVLRLRVN 732
            .....:..|....::|. |.::::|.:.|          .||.:|                  ||
Mouse   663 YNRIAKVLLEFEVLYHRAWLQQIEEIHAGLEASLLVKAPGTGELF------------------VN 709

  Fly   733 FLPEIITLAKEVRNIKNLGFRVPLTIVNKAHQANQIYPYAISLIES--------------VRTYE 783
            |.|:|:.|.:|.:.:..||..|.              |:|.:|.:.              :..||
Mouse   710 FDPQILVLFRETQCMSQLGLPVS--------------PFAAALFQKRDMFKKNFSDMKMMLSEYE 760

  Fly   784 R-------------------------------TLEKLNNRSLAQNSVFKIEDRASIVPLVAGLRK 817
            |                               |...||.....:|:..||:|...::..|..|.:
Mouse   761 RVKLKMPPAIEQLMFPHLARVDEALQPGLAVLTWTSLNIGGYLENAFAKIKDLELLLDRVNDLIE 825

  Fly   818 DVLNLVSEGIG--LIWESYKLDPYVIRLSECVTQFQEKVDDLLV------------VEEQ----- 863
            ..::.:.|.:.  .:.:..:.||....      :|.:...||.|            |||.
Mouse   826 FRIHAILEEMSSMALCQLPQDDPLTCE------EFLQMTKDLCVSGAQLLHFKSSLVEEAVNELI 884

  Fly   864 ---LDVDVRSLE------------------------------------TCPYSAA------TFV- 882
               |||||...|                                    :.|.:|.      |.|
Mouse   885 NMLLDVDVPPEEAAENVCHENASPSGNTSGRREGHSEALASSFNAGASSLPLTATARKKKETEVL 949

  Fly   883 ----EILSKIQHAVDDLSLR-------------QYSNL--------------------------- 903
                |:||...|...|..|:             .:|::
Mouse   950 EEARELLSHFNHQNTDALLKVTRNTLEAIRRRIHFSHMINFRDSNDASKAKQNHLPIFRASVTLA 1014

  Fly   904 --SVWVTRLDEEVEKKL------ALRLQAGIQAWTEALTGNKK-------EVDTSMDTDAPAQPT 953
              ::.:|...|::::.|      .:.:..|::.|:..|...:|       .|..:.|:|:.|:
Mouse  1015 IPNIAMTPALEDIQQTLNKAVECIISVPKGVRQWSSELLSKRKMHERKMAAVKNNEDSDSDAE-- 1077

  Fly   954 HKLGGDPQIQNAVHEIRITNQQMYLYPSIEEARFQIMQQFFAWQAIVTSQVRLQSTRYQVGLEKH 1018
                                        :||...|...:.    |.:...:.:|:..|
Mouse  1078 ----------------------------VEENELQETLEI----ASINLPIPVQTQNY------- 1103

  Fly  1019 VSQTYRNLLTKLPEGKILENAYGAIEQKVSEVRNYVDEWLRYQSLWDLQADMLYGRLGEDVNLWI 1083
                |:|:.......|::......|.....||...:|.:.||..:|..:.        ||..:..
Mouse  1104 ----YKNISDNKEIVKLVSVLSTVISSTKKEVITSMDRFKRYNHIWQKEK--------EDTIMTF 1156

  Fly  1084 KCLNDIK---QSRTTFDTS-----DTRRAY---GPIIIDYAKVQAKVTLKYDSW--------HKE 1129
            ...|.:.   :||..:..|     :....|   |.|.:..|.::..:|.:..:|        :::
Mouse  1157 IAQNPLLPEFESRILYFQSLEQEINAEPEYIRVGSIALYTADLKLSLTAETKAWMAVIGRHCNRK 1221

  Fly  1130 ALGKFGTLLGTEMTSFHSKVSKSRTDLEMQSIEAASTSDAVSFITYVQSLKKDMIAWDKQVEVFR 1194
            ...:...:| |.:.....|:|:...||:...|..|:          ::.:::..|:.|.||....
Mouse  1222 YRAEMENIL-TVVEESQKKLSRPIKDLDDIRIAMAA----------LKEIREQQISTDFQVGPIE 1275

  Fly  1195 EAQRILERQRFQFPNTWL-HVDNIEGEWSAFNEIIKRKDTAIQTQVASLQAKIVAE-DKAVETRT 1257
            |:..:|.:.........: .||.:...|    |.:..:.:.:|.::.:||.....| ...||...
Mouse  1276 ESYALLNKYGLLVAKEEMDKVDTLRYAW----EKLLARASDVQNELGALQPSFRKELISTVEVFL 1336

  Fly  1258 VD---FLNDWEKTKPTGGKIRPDDALQQLQIFESKYSRLKEERDNVVKAKEALELQESAVPNNSA 1319
            .|   |..|::...|....::|.:|..:|.||::::..:..:.......:|...|..:..|.
Mouse  1337 QDCQQFYLDYDLNGPMASGLKPQEASGRLIIFQNQFDNIYRKYITYTGGEELFGLPVTPYPQ--- 1398

  Fly  1320 ERMNVALE---ELQDLRGVWSELSKVWTQIDETREKPWLSVQPRKLRQQLEAMMAQLKELPARLR 1381
                 .||   :|..|:.::|..:.|...::..::..|..|...|:..:|.....:.::||..|:
Mouse  1399 -----LLEIKRQLNLLQKIYSLYNNVIETVNSYQDTLWSDVNIEKINNELLEFQNRCRKLPRALK 1458

  Fly  1382 MYESYEYVKKLIQSYIKVNMLIVELKSDALKERHWKQLT----KQLRVNWVLSDLSLGQVWDVNL 1442
            .::::..:||.|..:.:...|:..:.|:|:.||||:::|    ..|.|.  .....|..:.:..|
Mouse  1459 DWQAFLDLKKTIDDFSECCPLLEYMASNAMVERHWQRITALTGHSLDVG--NETFKLRNIMEAPL 1521

  Fly  1443 QKNEGIVKDIILVAQGEMALEEFLKQVRESWQNYELDLINYQNKCRIIRGWD---DLFNKVKEHI 1504
            .|.:..::||.:.|..|..:|:.|:||...|.|..|....::.:..::...|   ::...:::.:
Mouse  1522 LKYKEEIEDICISAVKERDIEQKLRQVINEWDNKTLTFSGFKTRGELLLRGDSTSEVIASMEDSL 1586

  Fly  1505 NSVAAMKLSPYYKVFEEEALTWEEKLNRINALFDVWIDVQRRWVYLEGIFSGSADIKTLLPVETS 1569
            ..:.::..:.|...|:.:...|.:.|:....:.:.|:.||..|:|||.:|.| .||...||.|..
Mouse  1587 MLLGSLLSNRYNMPFKAQIQKWVQCLSNSTDIIENWMTVQNLWIYLEAVFVG-GDIAKQLPKEAK 1650

  Fly  1570 RFQSISSEFLGLMKKVTKSPKVMD-VLNIPAVQRSLERLADLLGKIQKALGEYLERERTSFPRFY 1633
            ||.:|...::.:|.:..:.|.|:. .:....:.:.|..|.|.|...||:|..|||::|..||||:
Mouse  1651 RFSNIDKSWVKIMTRAHEIPNVVQCCVGDETMGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRFF 1715

  Fly  1634 FVGDEDLLEIIGNSKNIARLQKHFKKMFAGVAAILLNEE-NNVILGISSREGEEVHFMNPVSTVE 1697
            ||.|..||||:|.:.:...:|.|...:|..:..:..::: .:.||.|||||||.:....||  :.
Mouse  1716 FVSDPALLEILGQASDSHTIQAHLLNVFDNIKTVKFHDKIYDRILSISSREGETIELDKPV--MA 1778

  Fly  1698 HPKINEWLSLVEKQMRFTLASLLAQAVQDIKQ--FRDGKIDPQAYMEWCDKYQAQIVVLAAQILW 1760
            ...:..||:.:.::.:.:|..::.||..:|::  |:        .:|:...:.||:.:|..|:||
Mouse  1779 EGNVEVWLNSLLEESQSSLHLVIRQAAANIQEPGFQ--------LIEFLSSFPAQVGLLGIQMLW 1835

  Fly  1761 SEDVESALQQASENNQSKPMQRVLGNVESTLNVLADSVLQEQPPLRRRKLEHLINEFVHKRTVTR 1825
            :.|.|.||:.|..:  .|.||:........||:|.:...::...:.|.|.|.||...||:|.:..
Mouse  1836 TRDSEEALRNAKFD--KKIMQKTNQAFLELLNMLIEITTKDLSSMERVKYETLITIHVHQRDIFD 1898

  Fly  1826 RLLNNGVTSPKSFQWLCEMRFYFDPRQTEVLQQLTIHMANARFFYGFEYLGVQDRLVQTPLTDRC 1890
            .|.:..|.||..|:||.:.||||    .|...:..||:.:..|.|..|:||..||||.|||||||
Mouse  1899 DLCHMHVKSPTDFEWLKQCRFYF----KEDSDKTMIHITDVAFIYQNEFLGCTDRLVITPLTDRC 1959

  Fly  1891 YLTMTQALESRLGGSPFGPAGTGKTESVKALGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGA 1955
            |:|:.|||...:||:|.|||||||||:.|.:|..||::|:||||.:..||:.:||||.||.|.|:
Mouse  1960 YITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGS 2024

  Fly  1956 WGCFDEFNRLEERMLSACSQQIQTIQEALKYEMDSNKESITVELVGKQVRVSPDMAIFITMNPGY 2020
            |||||||||::..:||..:|||..|   |..:.:..|..|..:  |..|.::|:..:|:||||||
Mouse  2025 WGCFDEFNRIDLPVLSVAAQQISII---LTCKKEHKKSFIFTD--GDNVTMNPEFGLFLTMNPGY 2084

  Fly  2021 AGRSNLPDNLKKLFRSLAMTTPDRQLIAEVMLFSQGFRSAEKLACKIVPFFKLCDEQLSNQSHYD 2085
            |||..||:|||..|||:||..||||:|..|.|.|.||.....||.|....::||:||||.|.|||
Mouse  2085 AGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYQLCEEQLSKQVHYD 2149

  Fly  2086 FGLRALKSVLISAGNVKRDRIMKIKEQMKQRGDENIDEASVAENLPEQEILIQSVCETMVPKLVA 2150
            ||||.:.|||.:.|..||                    ||..:.  |..|:::.:.:..:.||:.
Mouse  2150 FGLRNILSVLRTLGAAKR--------------------ASPTDT--ESTIVMRVLRDMNLSKLID 2192

  Fly  2151 EDIPLLFSLLSDVFPNVGYTRAEMKGLKEEIRKVCQEDYLVCGEGDEQGAAWMEKGLGSTWVDKV 2215
            ||.||..||:.|:|||:...:|....|:..|.|..:|..|:               ....|..||
Mouse  2193 EDEPLFLSLIEDLFPNILLDKAGYPELETAISKQVEEAGLI---------------NHPPWKLKV 2242

  Fly  2216 LQLYQISNLNHGLMMVGPSGSGKSTAWKTLLKALERFEGVEGVAH---VIDPKAISKEALYGVLD 2277
            :||::...:.||:|.:|||||||:|...||:||:...    |..|   .::||||:...::|.||
Mouse  2243 IQLFETQRVRHGMMTLGPSGSGKTTCIHTLMKAMTDC----GKPHREMRMNPKAITAPQMFGRLD 2303

  Fly  2278 PNTREWTDGLFTHILRKIIDNVRGEINKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLS 2342
            ..|.:||||:|:.:.||.:...:||   ..||:.||.||..|:|||||||||||.|||.||:|:.
Mouse  2304 VATNDWTDGIFSTLWRKTLKAKKGE---HIWIVLDGPVDAIWIENLNSVLDDNKTLTLANGDRIP 2365

  Fly  2343 LPPNVRVMFEVQDLKFATLATVSRCGMVWFSEDVLSTEMIFENYLSRLRSIPLEDGDEDFVGVIK 2407
            :.||.:::||..::..|:.|||||.|||:.|..||....|.|.:|.| ||
Mouse  2366 MAPNCKIVFEPHNIDNASPATVSRNGMVFMSSSVLDWSPILEGFLKR-RS--------------- 2414

  Fly  2408 PAKDKEEEVSPSLQVQRDIALLLLPFFSADGIVVRTLEYAMDQEHIMDFTR-LRALSSLFSMLNQ 2471
               .:|.|:...|..:        .|.......::.||:.|:.......|: ...|..|.....|
Mouse  2415 ---PQEAEILRQLYAE--------TFPDLYRFSIQNLEFKMEVLEAFVITQSTHMLQGLIPPKEQ 2468

  Fly  2472 AARNVLTFNAQHPDFPCSADQLEHYIPKALVYSVLWSFAGDAKL--KVRIDLGDFVRSVTTVPLP 2534
            |..    .:.:|             :.:..|::::||.....:|  :.|::|....|...|:.||
Mouse  2469 AGE----VDPEH-------------LGRLFVFAMMWSVGAVLELEGRRRMELWLRSREGPTLHLP 2516

  Fly  2535 GA--AGAPIIDYEVNMSGDWVPWSNKVPVIEVETHKVASPD-------IVVPTLDTVRHESLLYT 2590
            ..  ||..:.||.|..:|.|..||...|      ..|..||       |:||.:|.||.:.|:.|
Mouse  2517 QLTDAGDTMFDYYVAPNGTWRHWSLCTP------EYVYPPDTTPEYGSILVPNVDNVRTDFLIKT 2575

  Fly  2591 WLAEHKPLVLCGPPGSGKTMTLFSALRAL-PDMEVV-GLNFSSATTPELLLKTFDHYCEYRKTPN 2653
            ...:.|.::|.|..|:.||:.:...:... |:..:| .|||||||||.:..:|.:.|.:.|.
Mouse  2576 IAKQGKAVLLIGEQGTAKTVIIKGFMSKFDPESHMVKNLNFSSATTPVMFQRTIESYVDKRM--- 2637

  Fly  2654 GVVLSPVQIGKWLVLFCDEINLPDMDSYGTQRVISFLRQLVEHKGFYRASDQA-WVSLERIQFVG 2717
            |....| ..||.:.:|.|::|:|.::.:|.|.....:|||:|..|||...... :.|:..|||:.
Mouse  2638 GTTYGP-PAGKKMAVFIDDLNMPVINEWGDQVTNEIVRQLMEQSGFYNLEKPGEFTSIVDIQFLA 2701

  Fly  2718 ACNPPTDPGRKPLSHRFLRHVPIIYVDYPGETSLKQIYGTFSRAMLRLMPALRGYAEPLTNAMVE 2782
            |...| ..||..:..|..|...|.....|.:.|:.:|:|.....   ...|.||::|.:.:|:::
Mouse  2702 AMIHP-GGGRNDIPQRLKRQFSIFNCTLPSDASMDKIFGVIGAG---YYCAQRGFSEEVQDALIK 2762

  Fly  2783 FYLASQDRFTQ----DMQP-----HYVYSPREMTRWVRGI----CEAIRPLDSLPVEGLVRLWAH 2834
            ....:: |..|    .|.|     |||::.|:::|..:|:    .|.|:..|.     |:|||.|
Mouse  2763 LVPLTR-RLWQMTKLKMLPTPAKFHYVFNLRDLSRIWQGMLNITSEVIKDTDE-----LLRLWKH 2821

  Fly  2835 EALRLFQDRLVDDSERRWTNEN-IDLV----GQKHFP---------------------GINQEEA 2873
            |..|:..||....|:..|.::. :.||    |::..|                     |...|||
Mouse  2822 ECKRVIADRFSMSSDVTWFDKAVVSLVEEEFGEEKAPVVDCGVDAYFVDFLRDAPEATGETPEEA 2886

  Fly  2874 -LQRPILYSNWLSKDYMPVNREELREYVHARLKVF---YEEEL---DVPLVLFDEVLDHVLRIDR 2931
             .:.|.||....|.::       |||    ||.||   |.|.:   .:.:|.|.:.:.|:::|.|
Mouse  2887 DAEMPKLYEPIASLNH-------LRE----RLSVFLQLYNESIRGTGMDMVFFIDAMVHLVKISR 2940

  Fly  2932 IFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSIFQIKVHNKYTSEDFDEDLRCVLRRSGCKDEK 2996
            :.|.|:|:.||:||.|:||.:|:|..:::.|.:.|||.:...|.:.:..|||:.:.|.:|.:.:.
Mouse  2941 VIRTPRGNALLVGVGGSGKQSLTRLASFIAGYTSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKG 3005

  Fly  2997 IAFILDESNVLDSGFLERMNTLLANGEVPGLFEGDE-------YTTLMTQCKEGAQREGLMLDSS 3054
            |.||..::.:.:..|||.||.:|::|||..||..||       .|.:|.  ||..:|.    .::
Mouse  3006 ITFIFTDNEIKEESFLEYMNNVLSSGEVSNLFARDEIDEINSDLTPIMK--KEHPRRP----PTN 3064

  Fly  3055 DELYKWFTQQVMRNLHVVFTMNPSTDGLKDRAATSPALFNRCVLNWFGDWSDSALFQVGKEFTTR 3119
            |.||::|..:|..|||:|...:|..:..::||...|||.:.|.::||..|...||..|.:.|.:.
Mouse  3065 DNLYEYFMSRVRGNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLSS 3129

  Fly  3120 VDLEKPNWHAPDFFPSVC------PLVPANPTHRDAVINSCVYVHQTLHQANARLAKRGGRTMAV 3178
            ..::             |      .||....:.:|.|...|           |...:|..|:..|
Mouse  3130 YTID-------------CTAEIKKELVQCMGSFQDGVAEKC-----------ADYFQRFRRSTHV 3170

  Fly  3179 TPRHYLDFIHHFVKLYNEKRSDLEEQQLHLNVGLNKIAETVEQVEEMQKSLAVKKQELQAKNEAA 3243
            ||:.||.||..:..:|.||..:::.....:|.||.|:.|..|.|..:.|.||.|::|||..||.|
Mouse  3171 TPKSYLSFIQGYKFIYEEKHMEVQSLANRMNTGLEKLKEASESVAALSKELAGKEKELQVANEKA 3235

  Fly  3244 NAKLKQMFQDQQEAEKKKIQSQEIQIRLADQTVKIEEKRKYVMADLAQVEPAVIDAQAAVKSIRK 3308
            :..||::....|.|||.|.:.|:::.:.......|.:.:......|...:||:.:|:||:::|:.
Mouse  3236 DTVLKEVTMKAQAAEKVKAEVQKVKDKAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIKP 3300

  Fly  3309 QQLVEVRTMANPPSVVKLALESICLLL-------------GENATDWKSIRAVIMRENFINSIVS 3360
            ..:..|||:..||.::...::.:.||.             |.....|:....::...||:.:: .
Mouse  3301 SDIATVRTLGRPPHLIMRIMDCVLLLFQRRVNAVKIDVDKGCTMPSWQESLKLMTAGNFLQNL-Q 3364

  Fly  3361 NFGTENITDDVREKMKSKYLSNPDYNFEKVNRASMACGPMVKWAIAQIEYADMLKRVEPLR---- 3421
            .|..:.|.::|.|.: :.|....|||.|...|.......:..|..|...:..:.|.|.||:
Mouse  3365 QFPKDTINEEVIEFL-NPYFEMSDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLI 3428

  Fly  3422 -EELRSLEEQADVNLASAKETKDLVEQLERSIAAYKEEYAQLISQAQAIKTDLENVQAKVDRSIA 3485
             :|.|.:....|:..|.|:     ::..:..:...:.||.|.:::.|.:..|.:..:.|:..:..
Mouse  3429 VQENRHILAMQDLQKAQAE-----LDAKQAELDVVQAEYEQAMAEKQTLLEDADRCRHKMQTAST 3488

  Fly  3486 LLKSLNIERERWESTSETFKSQMSTIIGDVLLSAAFIAYGGYFDQHYRLNLFTTWSQHLQAASIQ 3550
            |:..|..|:|||...|:.|.:|...::|||||:.||::|.|.|:|.:|..|...|.:.::|..|.
Mouse  3489 LISGLAGEKERWTEQSKEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLHDWKKEMKARKIP 3553

  Fly  3551 YRADIARTEYLSNPDERLRWQANALPTDDLCTENAIMLKRFNRYPLIIDPSGQATTFLLNEYAGK 3615
            :...:...|.|.:......|....||.|||..:|.|::.:.:||||:|||..|...::.|:.:..
Mouse  3554 FGNGLNLNEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESQN 3618

  Fly  3616 KITKTSFLDDSFRKNLESALRFGNPLLVQDV-ENYDPILNPVLNRELRRTGGRVLITLGDQDIDL 3679
            ::..||.....||.:||.:|..|.|||::|| |..||.|:.||.:...:||....:.:||:::|:
Mouse  3619 ELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLEKNFIKTGSTFKVKVGDKEVDV 3683

  Fly  3680 SPSFVIFLSTRDPTVEFPPDICSRVTFVNFTVTRSSLQSQCLNQVLKAERPDIDEKRSDLLKLQG 3744
            ...|.::::|:.|...:.|:|.:|.:.::||||...|:.|.|.:|:..|:.:::::|:.||:...
Mouse  3684 MDGFKLYITTKLPNPAYTPEISARTSIIDFTVTVKGLEDQLLGRVILTEKQELEKERTHLLEDVT 3748

  Fly  3745 EFRLRLRQLEKSLLQALNDAKGKILDDDSVITTLETLKKEAYDINQKVDETDKVIAEIETVSQQY 3809
            ..:.|:::||.:||..|...:|.:::|:|:|..|...||.|.::.||::.:.:...:|.:..::|
Mouse  3749 ANKRRMKELEDNLLYRLTSTQGSLVEDESLIIVLSNTKKTAEEVTQKLEISGETEIQINSAREEY 3813

  Fly  3810 LPLSVACSNIYFTMDSLNQVHFLYQYSLKMFLDIFSTVLYNNPKLEGRTDHSERLGIVTRDLFQV 3874
            .|::...|.:||.:..:..|:.:||.||:.||.:|...|..:.|   ....|:|:..:...:...
Mouse  3814 RPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVK---SPITSKRIANIIEHMTYE 3875

  Fly  3875 CYERVARGMIHIDRLTFALLMCKIHLKGTSESNLDAEFNFFLRSREGLLAN-----PTPVEGLSA 3934
            .::..|||:....:..|.||:.   ||...:.||.....|....:.|...:     |.|.:.:.
Mouse  3876 VFKYAARGLYEEHKFLFTLLLT---LKIDIQRNLVKHEEFLTLIKGGASLDLKACPPKPSKWIL- 3936

  Fly  3935 EQIESVNRLAL-RLPIFRKLLEKV-RSIPELGAWLQQSSP-EQVVPQLWDESKALSPIASSVHQL 3996
             .:..:|.:.| :|..|..:|::: |:......|..:.:| |:.:|..:|:|      .....:|
Mouse  3937 -DMTWLNLVELSKLKQFSDILDQISRNEKMWRVWFDKENPEEEPLPNAYDKS------LDCFRRL 3994

  Fly  3997 LLIQAFRPDRVIAAAHNVVNTVLGEDFMPNAEQELDFTSVVDKQLNCNTPALLCSVPGFDASGRV 4061
            |||:::.|||.||.|...:...:||::......:|:.|.   ::.:..||.:.....|.|.:..:
Mouse  3995 LLIRSWCPDRTIAQARKYIMDSMGENYAEGVILDLEKTW---EESDPRTPLICLLSMGSDPTDSI 4056

  Fly  4062 DDLAAEQNKQISSIAIGSAEGFNQAERAINMACKTGRWVLLKNVHLAPQWLVQLEKKMHSLQP-H 4125
            ..|......:...:::|..:..: |.:.::.....|.||||:|.||...:|.:|...:...:. |
Mouse  4057 IALGKRLKIETRYVSMGQGQEVH-ARKLLHQTMANGGWVLLQNCHLGLDFLDELMDVVTETETVH 4120

  Fly  4126 SGFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGIRANLLRTFSTVPAARM-MKTPSERARLYFLL 4189
            ..|||::|.|::.:.|:.||:....|..|||.|:||.|.||:..|....: :...::...:.:.:
Mouse  4121 DTFRLWITTEVHKQFPITLLQMSIKFANEPPQGLRAGLRRTYGGVSQDLLDVSVGAQWKPMLYAV 4185

  Fly  4190 AWFHAIVQERLRYVPLGWAKKYEFNESDLRVACDTLDTWIDTTAMGRTNLPPEK-VPWDALVTLL 4253
            |:.|:.||||.::.||||...||||::|.......:...:|       ::..:| |.|..:..::
Mouse  4186 AFLHSTVQERRKFGPLGWNIPYEFNQADFNATVQFIQNHLD-------DMDVKKGVSWTTVRYMI 4243

  Fly  4254 SQSIYGGKIDNDFDQRLLTSFLKKLFTARSFEADFALVANVDGASGGLRHITMPDGTRRDHFLKW 4318
            .:..|||::.:|:|:|||.:|.|..|:...|..||......:          :|..:..|.:|::
Mouse  4244 GEIQYGGRVTDDYDKRLLNTFAKVWFSENMFGPDFTFYQGYN----------IPKCSTVDGYLQY 4298

  Fly  4319 IENLTDRQTPSWLGLPNNAEKVLLTTRGTDLVSKLLKMQQLEDDDELAYSVEDQSEQSAVGRGED 4383
            |::|....:|...||..||:....:....|::..:|.:|.           :|.|     |.|::
Mouse  4299 IQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTILGIQP-----------KDSS-----GGGDE 4347

  Fly  4384 GRPSWMKTLHNSATAWLELLPKNLQ--VLKRTVENIK--DPLYRYFEREVTSGSRLLQTVILDLQ 4444
            .|.:.:..|   |...||.||::..  .:|..::.:.  .|:..:..:|:....|:|..|...|.
Mouse  4348 TREAVVARL---ADDMLEKLPEDYSPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLT 4409

  Fly  4445 DVVLICQGEKKQTNHHRSMLSELVRGIIPKGWKRYTVPAGCTVIQWITDFSNRVQQLQKVSQLVS 4509
            ::.|...|....:.:.|..|..:....||..||:.:. ...|:..|.|:.      |::..|..|
Mouse  4410 ELKLAVDGTIIMSENLRDALDCMFDARIPARWKKASW-VSSTLGFWFTEL------LERNCQFTS 4467

  Fly  4510 QAGAKELQGFP--VWLGGLLNPEAYITATRQCVAQAN-SWSLEELALDVTITDAGLKND----QK 4567
            ...    .|.|  .|:.|..||:.::||.||.:.:|| .|:|:.:.|...:|.. :|:|    ..
Mouse  4468 WVS----NGRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKF-MKDDISAPPT 4527

  Fly  4568 DCCFGVTGLKLQGAQC-KNNELLLAS--TIMMDL-PVTILKWIKISSE------PRISKLTLPVY 4622
            :..: |.||.|:||.. |.|..|:.|  .::.:| ||     |:|.:|      ||:  ...|:|
Mouse  4528 EGVY-VYGLYLEGAGWDKRNMKLIESKPKVLFELMPV-----IRIFAENNTARDPRL--YCCPIY 4584

  Fly  4623 LNSTRTELLFTVDLAVAAGQESHSFYERGVAVL 4655
            ....||:|.:...:.:...|....:..||||:|
Mouse  4585 KKPVRTDLNYIAAVDLKTAQAPEHWVLRGVALL 4617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhc64C	NP_001261432.1	DHC_N1	240..839	CDD:285571	129/715 (18%)
		DYN1	1022..4338	CDD:227570	986/3460 (28%)
		DHC_N2	1326..1724	CDD:285579	106/409 (26%)
		P-loop_NTPase	1870..2103	CDD:304359	123/232 (53%)
		P-loop_NTPase	2227..2367	CDD:304359	66/142 (46%)
		P-loop_NTPase	2572..2835	CDD:304359	84/285 (29%)
		Cas4_I-A_I-B_I-C_I-D_II-B	2834..>2943	CDD:294426	37/141 (26%)
		P-loop_NTPase	2916..3194	CDD:304359	87/290 (30%)
		MT	3208..3544	CDD:289543	94/353 (27%)
		AAA_9	3569..3784	CDD:289547	71/215 (33%)
		Dynein_heavy	3925..4636	CDD:281078	184/742 (25%)
Dnah5	NP_579943.3	Stem. /evidence=ECO:0000250	1..1938		417/2122 (20%)
		DHC_N1	248..802	CDD:285571	118/659 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	901..921		0/19 (0%)
		DHC_N2	1402..1804	CDD:285579	103/406 (25%)
		P-loop_NTPase	1939..2170	CDD:304359	126/255 (49%)
		AAA 1. /evidence=ECO:0000250	1939..2161		122/226 (54%)
		AAA 2. /evidence=ECO:0000250	2221..2440		93/267 (35%)
		P-loop_NTPase	2254..2389	CDD:304359	65/141 (46%)
		AAA 3. /evidence=ECO:0000250	2547..2800		77/261 (30%)
		P-loop_NTPase	2558..2822	CDD:304359	82/277 (30%)
		AAA 4. /evidence=ECO:0000250	2913..3167		81/283 (29%)
		P-loop_NTPase	2914..3183	CDD:304359	89/298 (30%)
		Stalk. /evidence=ECO:0000250	3182..3479		73/303 (24%)
		MT	3199..3543	CDD:289543	93/350 (27%)
		AAA 5. /evidence=ECO:0000250	3564..3794		74/229 (32%)
		AAA_9	3572..3788	CDD:289547	71/215 (33%)
		Dynein_heavy	3929..4610	CDD:281078	185/748 (25%)
		AAA 6. /evidence=ECO:0000250	4009..4223		57/217 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.710