DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7509 and RLP19

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_179112.1	Gene:	RLP19 / 815997	AraportID:	AT2G15080	Length:	983	Species:	Arabidopsis thaliana

Alignment Length:	521	Identity:	120/521 - (23%)
Similarity:	204/521 - (39%)	Gaps:	112/521 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 CNPD-------------TKSFTCWNTNLKSVPVTQVIPM------------------------NM 183
            |:||             |...:|:::|         ||:                        ::
plant    30 CDPDQSDAILEFKNEFETLEESCFDSN---------IPLKTESWTNNSDCCYWDGIKCDAKFGDV 85

  Fly   184 VNIDLSRNILS---TLHKDTFR--GLTVLKELDISHNVLDF---LPFDLFQDLDSLLVLRIQNNQ 240
            :.:|||.:.|.   ..:...||  .|..|..||:|:|  ||   :|..| :.|.:|..|.:..|.
plant    86 IELDLSFSCLRGQLNSNSSLFRLPQLRFLTTLDLSNN--DFIGQIPSSL-ETLSNLTTLDLSRNH 147

  Fly   241 LEDIDHRTFWKLRNLNILDLSKNEI-GMLPESIFYHAQRLTVINMCDNQIQNFPPNLLRDQLMLE 304
            .......:...|.:|..:|.|.|.. |.:|.|:.| ...||..|:..|......|:.:.:...|.
plant   148 FSGRIPSSIGNLSHLIFVDFSHNNFSGQIPSSLGY-LSHLTSFNLSYNNFSGRVPSSIGNLSYLT 211

  Fly   305 ELDMSRNK-ISELSS--GSIRYLTKLKTLDFGWNQIAKIDDDFFAG--------LRSLRTLSLHN 358
            .|.:|||. ..||.|  ||:.:||.|           .:|.:.|.|        |..|.::.||.
plant   212 TLRLSRNSFFGELPSSLGSLFHLTDL-----------ILDTNHFVGKIPSSLGNLSHLTSIDLHK 265

  Fly   359 NRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMS-SIPADLFLNVSA 422
            |...........||:.|.:..|:.|.|.....::|..||.|:.|.:..|.:| |.|..| ||:..
plant   266 NNFVGEIPFSLGNLSCLTSFILSDNNIVGEIPSSFGNLNQLDILNVKSNKLSGSFPIAL-LNLRK 329

  Fly   423 LTRLTLFSNNLTTLEADDFQGLNNLKIL-LLNNNILKNFDARAFEPLSQLEKLRIDSNKLM-FLP 485
            |:.|:||:|.||.....:...|:|||:. ...|:......:..|. :..|:.:.:::|:|. .|.
plant   330 LSTLSLFNNRLTGTLPSNMSSLSNLKLFDATENHFTGPLPSSLFN-IPSLKTITLENNQLNGSLG 393

  Fly   486 HGALHGLKNLVAVKLDKN----PWHCDCRALYLARWIREFVLKLWDGQQPMCRGPGDLGGHEVGL 546
            .|.:....||..::|..|    |.|   |::.....::|..|..::.|               ||
plant   394 FGNISSYSNLTVLRLGNNNFRGPIH---RSISKLVNLKELDLSNYNTQ---------------GL 440

  Fly   547 LR---YDDLCDGQWASMLSLSPRLPVRKHQISTPMNYTDYFNLYLKHIYNGTTDEELKEADITSV 608
            :.   :..|...::.::..|:....:..::|.:.....|..:|...|: :.|....|..:.:..:
plant   441 VDFTIFSHLKSIEYLNLSHLNTTTTIDMYEILSSFKLLDTLDLSGSHV-STTNKSSLSNSSLVLI 504

  Fly   609 S 609
            |
plant   505 S 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	20/66 (30%)
		leucine-rich repeat	187..206	CDD:275380	7/23 (30%)
		LRR_RI	<201..386	CDD:238064	56/201 (28%)
		leucine-rich repeat	207..230	CDD:275380	10/25 (40%)
		leucine-rich repeat	231..254	CDD:275380	4/22 (18%)
		LRR_8	253..313	CDD:290566	18/61 (30%)
		leucine-rich repeat	255..278	CDD:275380	8/23 (35%)
		leucine-rich repeat	279..302	CDD:275380	5/22 (23%)
		LRR_8	303..361	CDD:290566	21/68 (31%)
		leucine-rich repeat	303..326	CDD:275380	11/25 (44%)
		leucine-rich repeat	327..350	CDD:275380	5/30 (17%)
		LRR_8	349..407	CDD:290566	15/57 (26%)
		LRR_4	350..390	CDD:289563	10/39 (26%)
		leucine-rich repeat	351..374	CDD:275380	6/22 (27%)
		leucine-rich repeat	375..398	CDD:275380	6/22 (27%)
		LRR_8	398..>443	CDD:290566	16/45 (36%)
		leucine-rich repeat	399..422	CDD:275380	9/23 (39%)
		leucine-rich repeat	423..443	CDD:275380	7/19 (37%)
		leucine-rich repeat	471..494	CDD:275380	5/23 (22%)
		LRRCT	503..554	CDD:214507	10/57 (18%)
RLP19	NP_179112.1	PLN00113	3..>646	CDD:331614	120/521 (23%)
		leucine-rich repeat	114..137	CDD:275380	10/25 (40%)
		leucine-rich repeat	138..161	CDD:275380	4/22 (18%)
		leucine-rich repeat	162..185	CDD:275380	8/23 (35%)
		leucine-rich repeat	186..209	CDD:275380	5/22 (23%)
		leucine-rich repeat	210..233	CDD:275380	10/22 (45%)
		leucine-rich repeat	234..257	CDD:275380	7/33 (21%)
		leucine-rich repeat	258..281	CDD:275380	6/22 (27%)
		leucine-rich repeat	282..305	CDD:275380	6/22 (27%)
		leucine-rich repeat	306..329	CDD:275380	9/23 (39%)
		leucine-rich repeat	330..351	CDD:275380	7/20 (35%)
		leucine-rich repeat	354..377	CDD:275380	4/23 (17%)
		leucine-rich repeat	378..402	CDD:275380	5/23 (22%)
		leucine-rich repeat	403..424	CDD:275380	6/23 (26%)
		leucine-rich repeat	427..451	CDD:275380	6/38 (16%)
		leucine-rich repeat	452..477	CDD:275380	2/24 (8%)
		leucine-rich repeat	507..526	CDD:275380
		leucine-rich repeat	527..550	CDD:275380
		leucine-rich repeat	551..574	CDD:275380
		leucine-rich repeat	575..604	CDD:275380
		PLN00113	<604..692	CDD:331614
		leucine-rich repeat	605..630	CDD:275380
		leucine-rich repeat	631..655	CDD:275380
		PLN00113	<656..739	CDD:331614
		leucine-rich repeat	656..676	CDD:275380
		leucine-rich repeat	677..700	CDD:275380
		leucine-rich repeat	701..722	CDD:275380
		leucine-rich repeat	723..795	CDD:275380
		leucine-rich repeat	796..819	CDD:275380
		PLN00113	<808..962	CDD:331614
		leucine-rich repeat	820..843	CDD:275380
		leucine-rich repeat	844..867	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910