Protein Alignment CG7509 and Lrg1

DIOPT Version :10

• Sequence 1: NP_647931.1
• Gene: CG7509 / 38579
• FlyBaseID: FBgn0035575
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: NP_084072.1
• Gene: Lrg1 / 76905
• MGIID: 1924155
• Length: 342
• Species: Mus musculus
• Alignment Length: 386
• Identity: 89/386 - (23%)
• Similarity: 143/386 - (37%)
• Gaps: 80/386 - (20%)

  Fly   168 TNLKSVPVTQVIPMNMVNIDLSRNILSTLHKDTFRGLTVLKELDISHNVLDFLPFDLFQDLDSLL 232
            ::||...:.|....:.|:........|:|..||.       .|.:..:.|..||....|....|.
Mouse    31 SSLKECLILQSAEGSTVSCHGPTEFPSSLPADTV-------HLSVEFSNLTQLPAAALQGCPGLR 88

  Fly   233 VLRIQNNQLEDIDHRTFWKLRNLNILDLSKNEIGMLPESIFYHAQRLTVINMCDNQIQNFPPNLL 297
            .|.:.:|:|:.:.......:..|..|||::|.:..||..:|..:..|:.:.:.:||::......|
Mouse    89 ELHLSSNRLQALSPELLAPVPRLRALDLTRNALRSLPPGLFSTSANLSTLVLRENQLREVSAQWL 153

  Fly   298 RDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDDFFAGLRSLRTLSLHNNRIS 362
            :....|..||::.|::|.|.||.:..|..|.|||.|:|.:..:.:....|.|.|:.|.|..||:.
Mouse   154 QGLDALGHLDLAENQLSSLPSGLLASLGALHTLDLGYNLLESLPEGLLRGPRRLQRLHLEGNRLQ 218

  Fly   363 SLSGTIFNNLANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSIPADLFLNVSALTRLT 427
            .|..::......|..|.|..|::..:...:|..|.:|:.|.|..||:||.|..|:..:...||
Mouse   219 RLEDSLLAPQPFLRVLFLNDNQLVGVATGSFQGLQHLDMLDLSNNSLSSTPPGLWAFLGRPTR-- 281

  Fly   428 LFSNNLTTLEADDFQGLNNLKILLLNNNILKNFDARAFEPLSQLEKLRIDSNKLMFLPHGALHGL 492
                        |.|               ..||
Mouse   282 ------------DMQ---------------DGFD------------------------------- 288

  Fly   493 KNLVAVKLDKNPWHCDCRALYLARWIREFVLKLWDGQQPMCRGPGDLGGH------EVGLL 547
                   :..|||.||.....|.||:.....|::......|.||..:.|.      |:|.|
Mouse   289 -------ISHNPWICDKNLADLCRWLVANRNKMFSQNDTRCAGPEAMKGQRLLDVAELGSL 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR	185..>437	CDD:443914	65/251 (26%)
		leucine-rich repeat	187..206	CDD:275380	4/18 (22%)
		leucine-rich repeat	207..230	CDD:275380	5/22 (23%)
		leucine-rich repeat	231..254	CDD:275380	4/22 (18%)
		leucine-rich repeat	255..278	CDD:275380	8/22 (36%)
		leucine-rich repeat	279..302	CDD:275380	4/22 (18%)
		leucine-rich repeat	303..326	CDD:275380	9/22 (41%)
		leucine-rich repeat	327..350	CDD:275380	7/22 (32%)
		leucine-rich repeat	351..374	CDD:275380	6/22 (27%)
		leucine-rich repeat	375..398	CDD:275380	6/22 (27%)
		leucine-rich repeat	399..422	CDD:275380	9/22 (41%)
		leucine-rich repeat	423..443	CDD:275380	3/19 (16%)
		leucine-rich repeat	471..494	CDD:275380	0/22 (0%)
		PCC	476..>561	CDD:188093	16/78 (21%)
Lrg1	NP_084072.1	leucine-rich repeat	65..86	CDD:275380	5/20 (25%)
		LRR	<66..>272	CDD:443914	58/205 (28%)
		leucine-rich repeat	87..110	CDD:275380	4/22 (18%)
		leucine-rich repeat	111..134	CDD:275380	8/22 (36%)
		leucine-rich repeat	135..158	CDD:275380	4/22 (18%)
		leucine-rich repeat	159..182	CDD:275380	9/22 (41%)
		leucine-rich repeat	183..206	CDD:275380	7/22 (32%)
		leucine-rich repeat	207..230	CDD:275380	6/22 (27%)
		leucine-rich repeat	231..254	CDD:275380	6/22 (27%)
		leucine-rich repeat	255..278	CDD:275380	9/22 (41%)
		PCC	259..>341	CDD:188093	27/148 (18%)