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Protein Alignment CG7509 and TLR5

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_003259.2	Gene:	TLR5 / 7100	HGNCID:	11851	Length:	858	Species:	Homo sapiens

Alignment Length:	530	Identity:	120/530 - (22%)
Similarity:	207/530 - (39%)	Gaps:	133/530 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 SLDEFRQRYLLPLISSDTRNCSLNACESLGIVSQLLMLINSMPNGTQSAANDKKPPKSKANGHND 98
            |.::.|..||.|...      .||:.:|:...|..:.|:         ..::.:|
Human   153 SKNQIRSLYLHPSFG------KLNSLKSIDFSSNQIFLV---------CEHELEP---------- 192

  Fly    99 GDVNGGEINAMSHLANFDLVKRVRQIESRLRSVEQPVWHLATGSQIEWNHCTSGVCRCNPDTK-- 161
              :.|..::..|..|| .|..||                     .::|..|      .||...
Human   193 --LQGKTLSFFSLAAN-SLYSRV---------------------SVDWGKC------MNPFRNMV 227

  Fly   162 ------SFTCWNTNL---------KSVPVTQVIPMNMVNIDLSRNILSTLHKDTFRGL--TVLKE 209
                  |...|..::         ||...:.::..:::......:.:....::||.||  :.::.
Human   228 LEILDVSGNGWTVDITGNFSNAISKSQAFSLILAHHIMGAGFGFHNIKDPDQNTFAGLARSSVRH 292

  Fly   210 LDISHNVLDFLPFDLFQDLDSLLVLRIQNNQLEDIDHRTFWKLRNLNILDLSKNEIGMLPESIFY 274
            ||:||..:..|...:|:.|..|.||.:..|::..|....|:.|.||.:|:||.|.:|.|..|.||
Human   293 LDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLLGELYSSNFY 357

  Fly   275 HAQRLTVINMCDNQIQNFPPNLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQIAK 339
            ...::..|                        |:.:|.|:.:...:.::|.||:|||...|.:..
Human   358 GLPKVAYI------------------------DLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTT 398

  Fly   340 IDDDFFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAF-VELNNLNELF 403
            |.     .:.|:..:.|..|::.:|..  .|..|||:  .|:.||:.::|...| :.:.:|..|.
Human   399 IH-----FIPSIPDIFLSGNKLVTLPK--INLTANLI--HLSENRLENLDILYFLLRVPHLQILI 454

  Fly   404 LGQNSMSSIPADLFLNVS-ALTRLTLFSNNL-----TTLEADDFQGLNNLKILLLNNNILKNFDA 462
            |.||..||...|...:.: :|.:|.|..|.|     |.|..|.|:||::|::|.||:|.|.:...
Human   455 LNQNRFSSCSGDQTPSENPSLEQLFLGENMLQLAWETELCWDVFEGLSHLQVLYLNHNYLNSLPP 519

  Fly   463 RAFEPLSQLEKLRIDSNKLMFLPHGALHG-------------------LKNLVAVKLDKNPWHCD 508
            ..|..|:.|..|.::||:|..|.|..|..                   ..:|..:.:..|.:.|:
Human   520 GVFSHLTALRGLSLNSNRLTVLSHNDLPANLEILDISRNQLLAPNPDVFVSLSVLDITHNKFICE 584

  Fly   509 CRALYLARWI 518
            |.......|:
Human   585 CELSTFINWL 594

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.