DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7509 and Adgra3

DIOPT Version :9

Sequence 1:NP_647931.1 Gene:CG7509 / 38579 FlyBaseID:FBgn0035575 Length:615 Species:Drosophila melanogaster
Sequence 2:NP_598672.1 Gene:Adgra3 / 70693 MGIID:1917943 Length:1310 Species:Mus musculus


Alignment Length:266 Identity:66/266 - (24%)
Similarity:95/266 - (35%) Gaps:102/266 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   290 QNFPPNLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDDFFAGLRSLRTL 354
            |..||:.|.::.:  .|.:|.||||||.:||...|:.|:.||...|.|::|....|.||.||:.|
Mouse    61 QVLPPDTLPNRTV--TLILSNNKISELKNGSFSGLSLLERLDLRNNLISRIAPGAFWGLSSLKRL 123

  Fly   355 SLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSIPADLFLN 419
            .|.||||..|:..:|..|.|||.|:|:        ||.|..|:                      
Mouse   124 DLTNNRIGCLNADVFRGLTNLVRLNLS--------GNLFTSLS---------------------- 158

  Fly   420 VSALTRLTLFSNNLTTLEADDFQGLNNLKILLLNNNILKNFDARAFEPLSQLEKLRIDSNKLMFL 484
                                  ||                    .|:.|..|..|...:..|:  
Mouse   159 ----------------------QG--------------------TFDYLGSLRSLEFQTEYLL-- 179

  Fly   485 PHGALHGLKNLVAVKLDKNPWHCDCRALYLARWIREFVLKLWDGQQPMCRGPGDLGGHEVGLLRY 549
                                  |||..|::.||::|..:.:.|.:   |..|..|....|..::.
Mouse   180 ----------------------CDCNILWMHRWVKERNITVRDTR---CVYPKSLQAQPVTGVKQ 219

  Fly   550 DDL-CD 554
            :.| ||
Mouse   220 ELLTCD 225

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7509NP_647931.1 LRR_8 182..241 CDD:290566
leucine-rich repeat 187..206 CDD:275380
LRR_RI <201..386 CDD:238064 40/95 (42%)
leucine-rich repeat 207..230 CDD:275380
leucine-rich repeat 231..254 CDD:275380
LRR_8 253..313 CDD:290566 7/22 (32%)
leucine-rich repeat 255..278 CDD:275380
leucine-rich repeat 279..302 CDD:275380 4/11 (36%)
LRR_8 303..361 CDD:290566 26/57 (46%)
leucine-rich repeat 303..326 CDD:275380 11/22 (50%)
leucine-rich repeat 327..350 CDD:275380 9/22 (41%)
LRR_8 349..407 CDD:290566 20/57 (35%)
LRR_4 350..390 CDD:289563 16/39 (41%)
leucine-rich repeat 351..374 CDD:275380 10/22 (45%)
leucine-rich repeat 375..398 CDD:275380 8/22 (36%)
LRR_8 398..>443 CDD:290566 0/44 (0%)
leucine-rich repeat 399..422 CDD:275380 0/22 (0%)
leucine-rich repeat 423..443 CDD:275380 0/19 (0%)
leucine-rich repeat 471..494 CDD:275380 3/22 (14%)
LRRCT 503..554 CDD:214507 13/51 (25%)
Adgra3NP_598672.1 LRR 1 71..92 10/22 (45%)
leucine-rich repeat 72..95 CDD:275378 11/24 (46%)
LRR_RI <73..155 CDD:238064 38/91 (42%)
LRR_8 74..130 CDD:290566 26/55 (47%)
LRR 2 95..116 7/20 (35%)
leucine-rich repeat 96..119 CDD:275378 9/22 (41%)
LRR_8 118..171 CDD:290566 25/124 (20%)
LRR_4 119..158 CDD:289563 19/46 (41%)
LRR 3 119..140 10/20 (50%)
leucine-rich repeat 120..143 CDD:275378 10/22 (45%)
LRR 4 143..164 12/92 (13%)
leucine-rich repeat 144..167 CDD:275378 12/94 (13%)
LRRCT 178..>212 CDD:214507 12/60 (20%)
IG_like 238..330 CDD:214653
Ig 242..326 CDD:299845
HRM <352..405 CDD:280888
GPS 688..732 CDD:280071
7tm_4 751..>934 CDD:304433
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1065..1084
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1187..1208
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1221..1264
PDZ-binding. /evidence=ECO:0000255 1308..1310
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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