DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7509 and Lrfn4

DIOPT Version :9

Sequence 1:NP_647931.1 Gene:CG7509 / 38579 FlyBaseID:FBgn0035575 Length:615 Species:Drosophila melanogaster
Sequence 2:NP_001102978.1 Gene:Lrfn4 / 688721 RGDID:1585286 Length:636 Species:Rattus norvegicus


Alignment Length:295 Identity:78/295 - (26%)
Similarity:114/295 - (38%) Gaps:63/295 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   293 PPNLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDDFFAGLRSLRTLSLH 357
            |||:.|..:   ||.::.|.|..|.....|.:|.|..|....|.|.:|....|..|.|||:|.|.
  Rat    43 PPNVDRRTV---ELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLD 104

  Fly   358 NNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVE-LNNLNELFLGQNSMSSIPADLFLNVS 421
            .||:..|..:......||..|.|:.|::..|...||.: |::|.:|.:..|::..:|        
  Rat   105 GNRLVELGSSSLRGPVNLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQVP-------- 161

  Fly   422 ALTRLTLFSNNLTTLEADDFQGLNN---LKILLLNNNILKNFDARAFEPLSQLEKLRIDSNKLMF 483
                               :.|:.:   |..|.|::|::.......|..||||.:|.:.||:|..
  Rat   162 -------------------WAGIGSMPALHTLNLDHNLIDALPPGVFAQLSQLSRLDLTSNRLAT 207

  Fly   484 LPHGAL-------HGLKNLVAVKLDKNPWHCDCRALYLARWIREFVLKLWDGQQPMCRGPGDLGG 541
            |....|       ....:.:.:....||.||:|..|:|.|..|...|:       .|..|..|.|
  Rat   208 LAPDPLFSRGRDAEASPSPLVLSFSGNPLHCNCELLWLRRLARPDDLE-------TCASPPTLAG 265

  Fly   542 HEVGLLRYDDLCDGQWA---SMLSLSPRLPVRKHQ 573
                  ||      .||   ...|..|.|..|..|
  Rat   266 ------RY------FWAVPEGEFSCEPPLIARHTQ 288

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7509NP_647931.1 LRR_8 182..241 CDD:290566
leucine-rich repeat 187..206 CDD:275380
LRR_RI <201..386 CDD:238064 31/92 (34%)
leucine-rich repeat 207..230 CDD:275380
leucine-rich repeat 231..254 CDD:275380
LRR_8 253..313 CDD:290566 7/19 (37%)
leucine-rich repeat 255..278 CDD:275380
leucine-rich repeat 279..302 CDD:275380 4/8 (50%)
LRR_8 303..361 CDD:290566 20/57 (35%)
leucine-rich repeat 303..326 CDD:275380 6/22 (27%)
leucine-rich repeat 327..350 CDD:275380 7/22 (32%)
LRR_8 349..407 CDD:290566 19/58 (33%)
LRR_4 350..390 CDD:289563 14/39 (36%)
leucine-rich repeat 351..374 CDD:275380 7/22 (32%)
leucine-rich repeat 375..398 CDD:275380 8/23 (35%)
LRR_8 398..>443 CDD:290566 4/44 (9%)
leucine-rich repeat 399..422 CDD:275380 4/22 (18%)
leucine-rich repeat 423..443 CDD:275380 0/19 (0%)
leucine-rich repeat 471..494 CDD:275380 7/29 (24%)
LRRCT 503..554 CDD:214507 16/50 (32%)
Lrfn4NP_001102978.1 LRR 1 49..70 5/23 (22%)
leucine-rich repeat 50..73 CDD:275380 6/25 (24%)
PPP1R42 53..203 CDD:411060 45/176 (26%)
LRR 2 73..94 6/20 (30%)
leucine-rich repeat 74..97 CDD:275380 7/22 (32%)
LRR 3 97..118 8/20 (40%)
leucine-rich repeat 98..121 CDD:275380 7/22 (32%)
LRR 4 121..142 8/20 (40%)
leucine-rich repeat 122..146 CDD:275380 8/23 (35%)
LRR 5 146..169 5/49 (10%)
leucine-rich repeat 147..170 CDD:275380 5/49 (10%)
LRR 6 170..191 5/20 (25%)
leucine-rich repeat 171..194 CDD:275380 6/22 (27%)
LRR 7 194..215 8/20 (40%)
leucine-rich repeat 195..213 CDD:275380 6/17 (35%)
LRRCT 234..278 CDD:214507 18/62 (29%)
Ig 281..368 CDD:416386 3/8 (38%)
Ig strand A 281..284 CDD:409353 1/2 (50%)
Ig strand A' 288..291 CDD:409353 1/1 (100%)
Ig strand B 297..305 CDD:409353
Ig strand C 311..316 CDD:409353
Ig strand C' 319..321 CDD:409353
Ig strand D 327..331 CDD:409353
Ig strand E 334..338 CDD:409353
Ig strand F 348..355 CDD:409353
Ig strand G 358..368 CDD:409353
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 556..585
PDZ-binding 633..636
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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