DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7509 and Ppp1r7

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_075689.1	Gene:	Ppp1r7 / 66385	MGIID:	1913635	Length:	361	Species:	Mus musculus

Alignment Length:	335	Identity:	86/335 - (25%)
Similarity:	153/335 - (45%)	Gaps:	70/335 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 IPMNMVNIDLSRNILSTLHK--DTFRGLTVLKE---LDISHNVLDFLPFDLFQDLDSLLVLRIQN 238
            :.|..:|:|.....:...|.  ....||.|||:   |.:..|::..:  :..::|.||..|.:.:
Mouse    68 VDMETINLDRDAEDVDLTHYRIGKIEGLEVLKKVKSLCLRQNLIKCI--ENLEELQSLRELDLYD 130

  Fly   239 NQLEDIDHRTFWKLRNLNILDLSKNEIGMLPESIFYHAQRLTVINMCDNQIQNFPPNLLRDQLML 303
            ||::.|::  ...|..|.:||:|.|.:..: |.|    .:||                     .|
Mouse   131 NQIKKIEN--LEALTELEVLDISFNMLRNI-EGI----DKLT---------------------QL 167

  Fly   304 EELDMSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDDFFAGLRSLRTLSLHNNRISSLSGTI 368
            ::|.:..|||:::.  :|..|.:|:.|:.|.|:|..|::  ...|.:|.:|.|..|:|:.|..
Mouse   168 KKLFLVNNKINKIE--NISNLHQLQMLELGSNRIRAIEN--IDTLTNLESLFLGKNKITKLQN-- 226

  Fly   369 FNNLANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSIPADLFLNVSALTRLTLFSNNL 433
            .:.|.||..|.:.:||::.|:|  ...|.||.||:|..|.:..|..  ..|.:.||.|.:.||.:
Mouse   227 LDALTNLTVLSVQSNRLAKIEG--LQSLVNLRELYLSNNGIEVIEG--LENNNKLTMLDIASNRI 287

  Fly   434 TTLEADDFQGLNNLKILLLNNNILKNFDARAFEPLSQLEKLRIDSNKLMFLPHGALHGLKNLVAV 498
            ..:|  :...|..|:...:|:|:|:::        |.|::|:               |.::|..|
Mouse   288 KKIE--NISHLTELQEFWMNDNLLESW--------SDLDELK---------------GARSLETV 327

  Fly   499 KLDKNPWHCD 508
            .|::||...|
Mouse   328 YLERNPLQKD 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	15/63 (24%)
		leucine-rich repeat	187..206	CDD:275380	4/20 (20%)
		LRR_RI	<201..386	CDD:238064	50/187 (27%)
		leucine-rich repeat	207..230	CDD:275380	5/25 (20%)
		leucine-rich repeat	231..254	CDD:275380	6/22 (27%)
		LRR_8	253..313	CDD:290566	12/59 (20%)
		leucine-rich repeat	255..278	CDD:275380	7/22 (32%)
		leucine-rich repeat	279..302	CDD:275380	2/22 (9%)
		LRR_8	303..361	CDD:290566	18/57 (32%)
		leucine-rich repeat	303..326	CDD:275380	7/22 (32%)
		leucine-rich repeat	327..350	CDD:275380	7/22 (32%)
		LRR_8	349..407	CDD:290566	20/57 (35%)
		LRR_4	350..390	CDD:289563	13/39 (33%)
		leucine-rich repeat	351..374	CDD:275380	7/22 (32%)
		leucine-rich repeat	375..398	CDD:275380	7/22 (32%)
		LRR_8	398..>443	CDD:290566	14/44 (32%)
		leucine-rich repeat	399..422	CDD:275380	7/22 (32%)
		leucine-rich repeat	423..443	CDD:275380	6/19 (32%)
		leucine-rich repeat	471..494	CDD:275380	3/22 (14%)
		LRRCT	503..554	CDD:214507	3/6 (50%)
Ppp1r7	NP_075689.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..64
		LRR 1	78..99		4/20 (20%)
		LRR_4	99..140	CDD:289563	10/44 (23%)
		LRR 2	100..121		2/22 (9%)
		leucine-rich repeat	101..122	CDD:275380	3/22 (14%)
		LRR_4	121..163	CDD:289563	14/48 (29%)
		LRR_8	122..177	CDD:290566	19/82 (23%)
		LRR 3	122..143		6/22 (27%)
		leucine-rich repeat	123..144	CDD:275380	6/22 (27%)
		LRR_4	143..185	CDD:289563	15/69 (22%)
		LRR 4	144..165		7/25 (28%)
		leucine-rich repeat	145..166	CDD:275380	9/46 (20%)
		LRR_8	165..221	CDD:290566	19/80 (24%)
		LRR 5	166..187		6/22 (27%)
		leucine-rich repeat	167..188	CDD:275380	7/22 (32%)
		LRR_4	188..227	CDD:289563	13/42 (31%)
		LRR 6	188..209		6/22 (27%)
		leucine-rich repeat	189..210	CDD:275380	7/22 (32%)
		LRR_4	209..251	CDD:289563	14/45 (31%)
		LRR 7	210..231		6/22 (27%)
		leucine-rich repeat	211..232	CDD:275380	7/22 (32%)
		LRR_8	231..287	CDD:290566	21/59 (36%)
		LRR 8	232..253		7/22 (32%)
		leucine-rich repeat	233..254	CDD:275380	7/22 (32%)
		LRR_4	254..295	CDD:289563	14/44 (32%)
		LRR 9	254..275		8/22 (36%)
		leucine-rich repeat	255..276	CDD:275380	7/22 (32%)
		LRR_4	276..317	CDD:289563	13/50 (26%)
		LRR 10	276..297		6/22 (27%)
		leucine-rich repeat	277..298	CDD:275380	7/22 (32%)
		LRR 11	298..319		6/28 (21%)
		LRRcap	337..355	CDD:197729	1/1 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910