DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7509 and lgi2a

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_001034730.1	Gene:	lgi2a / 654827	ZFINID:	ZDB-GENE-060217-2	Length:	536	Species:	Danio rerio

Alignment Length:	155	Identity:	45/155 - (29%)
Similarity:	79/155 - (50%)	Gaps:	6/155 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   390 GNAFVEL---NNLNELFLGQNSMSSIPADLFLNVSALTRLTLFSNNLTTLEADDFQGLNNLKILL 451
            |:::|..   |:::.|.:...:.|.:...:|.::.:|..|.|.||.|||:..|.|.||.:|:.|.
Zfish    42 GSSYVPRYIPNDVSSLSIVNGTFSEVKEAMFSHMPSLQLLLLNSNALTTVRDDAFSGLPHLEYLF 106

  Fly   452 LNNNILKNFDARAFEPLSQLEKLRIDSNKLMFLPHGALHGLKNLVAVKLDKNPWHCDCRALYLAR 516
            :.||.::.....:|..|..|..|.:.:|.:..||......|.:|:.:.|..|.:.|||||.:|..
Zfish   107 IENNKIETTSKYSFRGLRDLTHLSLANNNIKALPRELFIDLDSLIELDLRGNVFECDCRAKWLMM 171

  Fly   517 WIREFVLKLWDGQQPMCRGPGDLGG 541
            |::.....:.|   .:|.||.::.|
Zfish   172 WLKSTNATVSD---VLCAGPEEMKG 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566
		leucine-rich repeat	187..206	CDD:275380
		LRR_RI	<201..386	CDD:238064
		leucine-rich repeat	207..230	CDD:275380
		leucine-rich repeat	231..254	CDD:275380
		LRR_8	253..313	CDD:290566
		leucine-rich repeat	255..278	CDD:275380
		leucine-rich repeat	279..302	CDD:275380
		LRR_8	303..361	CDD:290566
		leucine-rich repeat	303..326	CDD:275380
		leucine-rich repeat	327..350	CDD:275380
		LRR_8	349..407	CDD:290566	4/19 (21%)
		LRR_4	350..390	CDD:289563	45/155 (29%)
		leucine-rich repeat	351..374	CDD:275380
		leucine-rich repeat	375..398	CDD:275380	2/10 (20%)
		LRR_8	398..>443	CDD:290566	13/44 (30%)
		leucine-rich repeat	399..422	CDD:275380	3/22 (14%)
		leucine-rich repeat	423..443	CDD:275380	10/19 (53%)
		leucine-rich repeat	471..494	CDD:275380	6/22 (27%)
		LRRCT	503..554	CDD:214507	13/39 (33%)
lgi2a	NP_001034730.1	LRR_8	54..112	CDD:290566	19/57 (33%)
		LRR_8	100..158	CDD:290566	14/57 (25%)
		LRR_4	100..140	CDD:289563	9/39 (23%)
		leucine-rich repeat	102..125	CDD:275378	6/22 (27%)
		LRR_4	126..>158	CDD:289563	8/31 (26%)
		leucine-rich repeat	126..149	CDD:275378	6/22 (27%)
		leucine-rich repeat	150..162	CDD:275378	3/11 (27%)
		LRRCT	158..198	CDD:214507	13/39 (33%)
		EPTP	210..251	CDD:281697
		EPTP	257..297	CDD:281697
		EPTP	302..348	CDD:281697
		EPTP	351..393	CDD:281697
		EPTP	398..439	CDD:281697
		EPTP	443..484	CDD:281697
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000