DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7509 and rxfp2b

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_001315011.1	Gene:	rxfp2b / 566888	ZFINID:	ZDB-GENE-110408-27	Length:	750	Species:	Danio rerio

Alignment Length:	438	Identity:	107/438 - (24%)
Similarity:	169/438 - (38%)	Gaps:	127/438 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 NDKKPPKSKANGHNDGDVNGGEINAMSHLANFDLVKRVRQIESRLRSVEQPVWHLATGSQIEWNH 148
            |::|...:.|:..|.||.:|..          ||..|..:     |...|   .|||..|:|.
Zfish    60 NNQKDCPNGADEDNCGDNSGWA----------DLFDRTFK-----RGYLQ---ELATDCQVEQ-- 104

  Fly   149 CTSGVCRC-NPDTKSFTCWNTNLKSVP-----VT---------QVIP-------MNMVNIDLSRN 191
             ...|||| |.:   ..|.:.:|:|:|     ||         :.:|       :.:..:.|..|
Zfish   105 -YPDVCRCINTE---IHCVHASLRSIPQVSANVTSLSLKSNKIRTLPDEAFIKYIKLQRLFLQDN 165

  Fly   192 ILSTLHKDTFRGLTVLKELDISHNVLDFLPFDLFQDLDSLLVLRIQNNQLEDIDHRTFWKLRN-- 254
            .::|:....|.||..|::|.:|.|.:..|...:|:||..|..|.:.:|.:..|...||..|.:
Zfish   166 CINTVSIQAFSGLYKLQKLSLSQNSISLLSPGVFRDLRKLKWLILDDNPITTIAANTFAGLSSLF 230

  Fly   255 -----------------------LNILDLSKNEIGMLPESIFYHAQRLTVINMCDNQIQNFPPNL 296
                                   |:.||...|.|..|..|.....:.|||:::..|.|::.|.|.
Zfish   231 FLSMVNTSLEALPSARLCAHMPFLSWLDFEGNSITTLGLSTLLDCEHLTVLSLRANLIKSLPENT 295

  Fly   297 LRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDDFFAGLRSLRTLSLHNNRI 361
            .:...|:.:||:|.|.|.||..|                        .|..||||::|:|..|.:
Zfish   296 FQSLRMMGDLDLSNNSIKELPVG------------------------IFKDLRSLQSLNLSQNPL 336

  Fly   362 SSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVELNNLNELFL--------------------GQ 406
            ..:....||:|..|.:|.|....|.:|..:.|..::||:.::.                    |.
Zfish   337 DHIHPGQFNHLIQLQSLGLEGVEIPNIQTSMFRPMDNLSYIYFKKFQYCSYAPHVRKCKPNSDGL 401

  Fly   407 NSMSSIPADLFLNVS--ALTRLTLFSNNL-----TTLEADDFQGLNNL 447
            :|...:.|::.|.||  .:..:|.|.|..     |.|.|:     |||
Zfish   402 SSFEDLLANVVLRVSVWVMAFITCFGNLFVIGMRTVLRAE-----NNL 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	17/58 (29%)
		leucine-rich repeat	187..206	CDD:275380	6/18 (33%)
		LRR_RI	<201..386	CDD:238064	55/209 (26%)
		leucine-rich repeat	207..230	CDD:275380	8/22 (36%)
		leucine-rich repeat	231..254	CDD:275380	7/22 (32%)
		LRR_8	253..313	CDD:290566	19/84 (23%)
		leucine-rich repeat	255..278	CDD:275380	7/22 (32%)
		leucine-rich repeat	279..302	CDD:275380	7/22 (32%)
		LRR_8	303..361	CDD:290566	16/57 (28%)
		leucine-rich repeat	303..326	CDD:275380	8/22 (36%)
		leucine-rich repeat	327..350	CDD:275380	2/22 (9%)
		LRR_8	349..407	CDD:290566	18/77 (23%)
		LRR_4	350..390	CDD:289563	13/39 (33%)
		leucine-rich repeat	351..374	CDD:275380	7/22 (32%)
		leucine-rich repeat	375..398	CDD:275380	6/22 (27%)
		LRR_8	398..>443	CDD:290566	14/71 (20%)
		leucine-rich repeat	399..422	CDD:275380	7/44 (16%)
		leucine-rich repeat	423..443	CDD:275380	6/24 (25%)
		leucine-rich repeat	471..494	CDD:275380
		LRRCT	503..554	CDD:214507
rxfp2b	NP_001315011.1	LDLa	39..74	CDD:238060	3/13 (23%)
		leucine-rich repeat	114..132	CDD:275380	4/20 (20%)
		LRR_RI	130..360	CDD:238064	61/253 (24%)
		leucine-rich repeat	133..156	CDD:275380	3/22 (14%)
		LRR_8	156..215	CDD:290566	17/58 (29%)
		leucine-rich repeat	157..180	CDD:275380	6/22 (27%)
		leucine-rich repeat	181..204	CDD:275380	8/22 (36%)
		LRR_8	203..288	CDD:290566	18/84 (21%)
		leucine-rich repeat	205..228	CDD:275380	7/22 (32%)
		leucine-rich repeat	229..253	CDD:275380	0/23 (0%)
		leucine-rich repeat	254..277	CDD:275380	7/22 (32%)
		LRR_8	277..336	CDD:290566	24/82 (29%)
		leucine-rich repeat	278..301	CDD:275380	7/22 (32%)
		leucine-rich repeat	302..325	CDD:275380	10/46 (22%)
		LRR_8	324..378	CDD:290566	17/53 (32%)
		leucine-rich repeat	326..349	CDD:275380	7/22 (32%)
		leucine-rich repeat	350..369	CDD:275380	5/18 (28%)
		7tm_4	419..>556	CDD:304433	9/31 (29%)
		7tm_1	<487..686	CDD:278431
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910