DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7509 and lrig3

DIOPT Version :9

Sequence 1:NP_647931.1 Gene:CG7509 / 38579 FlyBaseID:FBgn0035575 Length:615 Species:Drosophila melanogaster
Sequence 2:NP_001103817.1 Gene:lrig3 / 564554 ZFINID:ZDB-GENE-130530-866 Length:1070 Species:Danio rerio


Alignment Length:481 Identity:125/481 - (25%)
Similarity:210/481 - (43%) Gaps:65/481 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   140 TGSQIEWNH--CTSGVCRCNPDTKSFTCWNTNLKSVPVTQVIPMNMVNIDLSRNILSTLHKDTFR 202
            ||......|  |.| ||.|..:...  |  :.||:....:.:|..:..:|||.|.|....:..|.
Zfish    24 TGDSRRTEHEPCPS-VCSCTGNLAD--C--SRLKAGRTVERLPARITRLDLSHNKLRVFPEALFS 83

  Fly   203 GLTVLKELDISHNVLDFLPFDLFQDLDSLLVLRIQNNQLEDIDHRTFWKLRNLNILDLSKNEI-- 265
            .|..|.|:.:|:|..:.:| ||..:..:|..|.:.:|::..:.......|..|..||||.|.|  
Zfish    84 SLPQLSEIKLSNNEFESIP-DLGPNAGNLSSLILASNRIGRVSSERLSPLLTLETLDLSNNNIVD 147

  Fly   266 ---GMLP----ESIFYHAQR---------------LTVINMCDNQIQNFPP-----------NLL 297
               |..|    :::|.:..|               |.|:.:..|::.:.|.           .|.
Zfish   148 VYAGAFPPIPLKNLFMNNNRISTLEHGCFSNLSSSLLVLKLNKNRLNSIPAKIFSLPHLQHLELS 212

  Fly   298 RDQLM------------LEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDDFFAGLRS 350
            |::|.            |..|.|.||.||.|..|:...|..::.|...:|.:.::...:..||.:
Zfish   213 RNRLRRVEGLTFQGLHGLRSLKMQRNGISRLMDGAFWGLNNMEVLQLEFNNLTEVSKGWLYGLLT 277

  Fly   351 LRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSIPAD 415
            |:.|.|.:|.||.:....:.....|..|||:.|::|.::..:||.|:.|.:|.:|.|.:|.|...
Zfish   278 LQQLHLSHNSISRIKPDAWEFCQKLAELDLSWNQLSRLEEGSFVGLSVLEQLHIGNNRISFIADG 342

  Fly   416 LFLNVSALTRLTLFSNNLT-TLE--ADDFQGLNNLKILLLNNNILKNFDARAFEPLSQLEKLRID 477
            .|..::.|..|.|..|.:: |:|  ...|..|:||:.|.|..|.:::...::|..|..||:|.:.
Zfish   343 AFRGLTNLQTLDLKFNEISWTIEDMNGPFSALDNLRKLFLQGNRIRSVTRKSFTGLEMLEQLDLS 407

  Fly   478 SNKLMFLPHGALHGLKNLVAVKLDKNPWHCDCRALYLARWIRE--FVLKLWDGQQPMCRGPGDLG 540
            :|.:|.|...|...:|.|..:.|:.:...|||:..:.:.|:.|  |:..|    ...|..|..|.
Zfish   408 NNAIMSLQANAFSQMKKLSELHLNTSSLLCDCQLKWFSLWVAEQAFLALL----NASCAHPHLLK 468

  Fly   541 GHEVGLLRYDD-LCDGQWASMLSLSP 565
            |..|..:..|: :||......:::.|
Zfish   469 GRSVFSIAQDEFVCDDFPKPQITVQP 494

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7509NP_647931.1 LRR_8 182..241 CDD:290566 17/58 (29%)
leucine-rich repeat 187..206 CDD:275380 7/18 (39%)
LRR_RI <201..386 CDD:238064 56/231 (24%)
leucine-rich repeat 207..230 CDD:275380 7/22 (32%)
leucine-rich repeat 231..254 CDD:275380 4/22 (18%)
LRR_8 253..313 CDD:290566 23/106 (22%)
leucine-rich repeat 255..278 CDD:275380 10/31 (32%)
leucine-rich repeat 279..302 CDD:275380 6/33 (18%)
LRR_8 303..361 CDD:290566 18/57 (32%)
leucine-rich repeat 303..326 CDD:275380 10/22 (45%)
leucine-rich repeat 327..350 CDD:275380 4/22 (18%)
LRR_8 349..407 CDD:290566 18/57 (32%)
LRR_4 350..390 CDD:289563 12/39 (31%)
leucine-rich repeat 351..374 CDD:275380 6/22 (27%)
leucine-rich repeat 375..398 CDD:275380 9/22 (41%)
LRR_8 398..>443 CDD:290566 14/47 (30%)
leucine-rich repeat 399..422 CDD:275380 7/22 (32%)
leucine-rich repeat 423..443 CDD:275380 7/22 (32%)
leucine-rich repeat 471..494 CDD:275380 7/22 (32%)
LRRCT 503..554 CDD:214507 13/53 (25%)
lrig3NP_001103817.1 LRR_RI <62..330 CDD:238064 66/268 (25%)
LRR_8 63..121 CDD:290566 17/58 (29%)
leucine-rich repeat 64..87 CDD:275378 7/22 (32%)
leucine-rich repeat 88..110 CDD:275378 7/22 (32%)
LRR_8 110..168 CDD:290566 14/57 (25%)
leucine-rich repeat 111..134 CDD:275380 4/22 (18%)
leucine-rich repeat 135..156 CDD:275380 9/20 (45%)
leucine-rich repeat 158..205 CDD:275380 6/46 (13%)
LRR_8 204..264 CDD:290566 15/59 (25%)
leucine-rich repeat 206..229 CDD:275380 3/22 (14%)
leucine-rich repeat 230..253 CDD:275380 10/22 (45%)
LRR_RI 251..>435 CDD:238064 52/183 (28%)
LRR_8 253..312 CDD:290566 15/58 (26%)
leucine-rich repeat 254..277 CDD:275380 4/22 (18%)
leucine-rich repeat 278..301 CDD:275380 6/22 (27%)
LRR_8 301..360 CDD:290566 20/58 (34%)
leucine-rich repeat 302..325 CDD:275380 9/22 (41%)
leucine-rich repeat 326..349 CDD:275380 7/22 (32%)
LRR_8 376..431 CDD:290566 16/54 (30%)
leucine-rich repeat 377..400 CDD:275380 6/22 (27%)
leucine-rich repeat 401..422 CDD:275380 7/20 (35%)
TPKR_C2 435..483 CDD:301599 13/51 (25%)
I-set 488..591 CDD:254352 1/7 (14%)
Ig 505..581 CDD:143165
I-set 595..685 CDD:254352
Ig_1 612..686 CDD:143240
I-set 689..776 CDD:254352
IGc2 703..766 CDD:197706
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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