Protein Alignment CG7509 and lingo1b

DIOPT Version :10

• Sequence 1: NP_647931.1
• Gene: CG7509 / 38579
• FlyBaseID: FBgn0035575
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: NP_001004576.1
• Gene: lingo1b / 447837
• ZFINID: ZDB-GENE-040912-136
• Length: 622
• Species: Danio rerio
• Alignment Length: 432
• Identity: 115/432 - (26%)
• Similarity: 186/432 - (43%)
• Gaps: 38/432 - (8%)

  Fly   117 LVKRVRQIESRLRSVEQPVWHLATGSQIEWN--HCTSGVCRCNPDTKSFTCWNTNLKSVPVTQVI 179
            :|.|.....|.|.:..||:..|..|:.:..:  .|.|. |.|:...:|..|....|.::|  :.|
Zfish    10 MVAREASGHSYLVACWQPILILMLGTVLSGSATGCPSR-CECSAQERSVVCHRRKLITLP--EGI 71

  Fly   180 PMNMVNIDLSRNILSTLHKDTFRGLTVLKELDISHNVLDFLPFDLFQDLDSLLVLRIQNNQLEDI 244
            |::...:|||:|.|..::.:.|.....|::|.::.|::..:....|.:|..|..|.::||.|:.|
Zfish    72 PIDTRLLDLSKNRLKAINPEEFLNYPQLEDLQLNENIISVIEPGAFSNLLGLRTLGLRNNNLKLI 136

  Fly   245 DHRTFWKLRNLNILDLSKNEIGMLPESIFYHAQRLTVINMCDNQIQNFPPNLLRDQLMLEELDMS 309
            ....|..|.||..||:|:|:|.:|.:.:|.....|..:.:.||.:.............||:|.|.
Zfish   137 QLGVFTGLSNLTRLDISENKIVILLDYMFQELYNLKELEVGDNDLVFISHRAFHGLSSLEQLTME 201

  Fly   310 RNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDDFFAGLRSLRTLSLHN-NRISSLSGTIFNNLA 373
            |..::.:.:.:..:|..|.||......:..|.|..|..|..|:.|.:.| ..:.||:....:.|
Zfish   202 RCNLTSVPTEAFSHLHNLLTLKLRHLNVNVIRDFSFRRLYRLKILEIANWPLLESLTAKSLHGL- 265

  Fly   374 NLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSIPADLFLNVSALTRLTLFSNNLTTLEA 438
            |:.||.:|...::.:...|...|..|....|..|.:..:..:...|:..|....|....|.::|.
Zfish   266 NITTLSITNCNLTAVPYVAIQHLVYLRFFNLSFNPIEVVEGNKMHNLLRLQAFHLVGGRLVSIEP 330

  Fly   439 DDFQGLNNLKILLLNNNILKNFDARAFEPLSQLEKLRIDSNKLMFLPHGALHGLKNLVAVKLDKN 503
            ..|:|||.|::                        |.:.||.|..|...|.|.:.||..:.|..|
Zfish   331 YSFKGLNYLRV------------------------LNVSSNSLSTLEESAFHSVGNLETLALHDN 371

  Fly   504 PWHCDCRALYL--ARWIREFVLKLWDGQQPMCRGPGDLGGHE 543
            |..||||.|::  .||...|     :.|||.|..|..|.|.|
Zfish   372 PLACDCRLLWVFRRRWRLNF-----NRQQPSCETPEFLQGKE 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR	185..>437	CDD:443914	63/252 (25%)
		leucine-rich repeat	187..206	CDD:275380	6/18 (33%)
		leucine-rich repeat	207..230	CDD:275380	5/22 (23%)
		leucine-rich repeat	231..254	CDD:275380	8/22 (36%)
		leucine-rich repeat	255..278	CDD:275380	8/22 (36%)
		leucine-rich repeat	279..302	CDD:275380	3/22 (14%)
		leucine-rich repeat	303..326	CDD:275380	6/22 (27%)
		leucine-rich repeat	327..350	CDD:275380	7/22 (32%)
		leucine-rich repeat	351..374	CDD:275380	6/23 (26%)
		leucine-rich repeat	375..398	CDD:275380	5/22 (23%)
		leucine-rich repeat	399..422	CDD:275380	4/22 (18%)
		leucine-rich repeat	423..443	CDD:275380	5/19 (26%)
		leucine-rich repeat	471..494	CDD:275380	7/22 (32%)
		PCC	476..>561	CDD:188093	27/70 (39%)
lingo1b	NP_001004576.1	Ig strand G	509..512	CDD:409353
		LRRNT	43..77	CDD:214470	10/36 (28%)
		LRR 1	74..95		6/20 (30%)
		leucine-rich repeat	75..98	CDD:275380	6/22 (27%)
		LRR	77..>373	CDD:443914	80/320 (25%)
		LRR 2	98..119		4/20 (20%)
		leucine-rich repeat	99..146	CDD:275380	13/46 (28%)
		LRR 3	122..143		7/20 (35%)
		LRR 4	146..167		9/20 (45%)
		leucine-rich repeat	147..170	CDD:275380	8/22 (36%)
		LRR 5	170..191		3/20 (15%)
		leucine-rich repeat	171..194	CDD:275380	3/22 (14%)
		LRR 6	194..215		5/20 (25%)
		leucine-rich repeat	195..218	CDD:275380	6/22 (27%)
		LRR 7	218..239		6/20 (30%)
		leucine-rich repeat	219..242	CDD:275380	7/22 (32%)
		leucine-rich repeat	243..290	CDD:275380	12/47 (26%)
		LRR 8	266..287		5/20 (25%)
		LRR 9	290..311		3/20 (15%)
		leucine-rich repeat	291..338	CDD:275380	11/46 (24%)
		LRR 10	314..335		5/20 (25%)
		LRR 11	338..359		7/44 (16%)
		leucine-rich repeat	339..362	CDD:275380	8/46 (17%)
		PCC	343..>425	CDD:188093	27/71 (38%)
		Ig	425..516	CDD:472250
		Ig strand B	444..448	CDD:409353
		Ig strand C	457..461	CDD:409353
		Ig strand E	482..486	CDD:409353
		Ig strand F	496..501	CDD:409353