DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7509 and f-cup

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_001262544.1	Gene:	f-cup / 41677	FlyBaseID:	FBgn0028487	Length:	802	Species:	Drosophila melanogaster

Alignment Length:	475	Identity:	115/475 - (24%)
Similarity:	188/475 - (39%)	Gaps:	115/475 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 TGPSQAKEPPIQSLDEFRQRYLLPLISSDTRNCSL-------NACESLGIVSQLLMLINSMPNGT 79
            :.||.::.|  :|....||   ..::.|...||:.       :..|...:::|.|..: :..:||
  Fly    53 SNPSTSRIP--RSAQSPRQ---ASVVHSPRTNCAFRPIFHERSTHEDDQVLTQELWKL-ARKSGT 111

  Fly    80 QSAAND--KKPPKSKANGHNDGDVNGGEINAMSHLANFDLVKRVRQIESRLRSVEQPVWHLATGS 142
            .:.:|.  .:.||...      |:|  |.:|.|...|.:          :|...|:..|
  Fly   112 LNLSNKALARVPKRLY------DIN--EADADSKAVNLE----------QLTIKEEDAW------ 152

  Fly   143 QIEWNHCTSGVCRCNPDTKSFTCWNTNLKSVPVTQVIPMNMVNIDLSRNILSTLHK--DTFRGLT 205
               ||.                              :|:|  |:|||.|.|:.:..  :..:.||
  Fly   153 ---WNQ------------------------------VPLN--NLDLSSNTLTHISPKIENLQSLT 182

  Fly   206 VLK--------------------ELDISHNVLDFLPFDLFQDLDSLLVLRIQNNQLEDIDHRTFW 250
            ||.                    .|::|||.|..||..:: .|..|..|.|..|:..:: :....
  Fly   183 VLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMY-SLPELRHLNISYNEFVEL-NPDIS 245

  Fly   251 KLRNLNILDLSKNEIGMLPESIFYHAQRLTVINMCDNQIQNFPPNLLRDQLMLEELDMSRNKISE 315
            .|..|..||...|.|..||..|.: ..|||.:.:..|.|:..||:|: :...|:::|:..|.::.
  Fly   246 DLHMLEFLDGGHNNIQSLPGGIGF-LVRLTALLLPYNHIKELPPDLV-NMRSLQKIDLMHNDLTS 308

  Fly   316 LSSGSIRYLTKLKTLDFGWNQIAKIDDDFFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLDL 380
            |.. .:..|.||..|....|.|.::.:  |.|..:|..|...||.|..:...:.:||.:|..|||
  Fly   309 LPE-DMGLLRKLDCLYLQHNDILELPE--FEGNEALNELHASNNFIKIIPKAMCSNLPHLKILDL 370

  Fly   381 TTNRISHIDGNAFVELNNLNELFLGQNSMSSIPADLFLNVSALTRLTLFSNNLTTLEADDFQ-GL 444
            ..|:|:.:.....: |.|||.|.:..|::|.:|..| .:::.|..|.:..|.:.|:..|..| |
  Fly   371 RDNKITELPDELCL-LRNLNRLDVSNNTISVLPVTL-SSLAHLISLQVEGNPIKTIRRDILQCG- 432

  Fly   445 NNLKILLLNNNILKNFDARA 464
                    ...|||....||
  Fly   433 --------TTRILKTLHDRA 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	23/80 (29%)
		leucine-rich repeat	187..206	CDD:275380	6/20 (30%)
		LRR_RI	<201..386	CDD:238064	57/204 (28%)
		leucine-rich repeat	207..230	CDD:275380	9/42 (21%)
		leucine-rich repeat	231..254	CDD:275380	5/22 (23%)
		LRR_8	253..313	CDD:290566	19/59 (32%)
		leucine-rich repeat	255..278	CDD:275380	8/22 (36%)
		leucine-rich repeat	279..302	CDD:275380	7/22 (32%)
		LRR_8	303..361	CDD:290566	16/57 (28%)
		leucine-rich repeat	303..326	CDD:275380	5/22 (23%)
		leucine-rich repeat	327..350	CDD:275380	6/22 (27%)
		LRR_8	349..407	CDD:290566	18/57 (32%)
		LRR_4	350..390	CDD:289563	13/39 (33%)
		leucine-rich repeat	351..374	CDD:275380	7/22 (32%)
		leucine-rich repeat	375..398	CDD:275380	7/22 (32%)
		LRR_8	398..>443	CDD:290566	14/45 (31%)
		leucine-rich repeat	399..422	CDD:275380	7/22 (32%)
		leucine-rich repeat	423..443	CDD:275380	6/20 (30%)
		leucine-rich repeat	471..494	CDD:275380
		LRRCT	503..554	CDD:214507
f-cup	NP_001262544.1	leucine-rich repeat	111..140	CDD:275380	9/36 (25%)
		LRR_RI	155..>377	CDD:238064	66/260 (25%)
		leucine-rich repeat	158..180	CDD:275380	7/23 (30%)
		LRR_8	180..235	CDD:290566	15/55 (27%)
		leucine-rich repeat	181..203	CDD:275380	4/21 (19%)
		leucine-rich repeat	204..226	CDD:275380	8/22 (36%)
		LRR_8	225..283	CDD:290566	17/59 (29%)
		leucine-rich repeat	227..249	CDD:275380	5/22 (23%)
		leucine-rich repeat	250..272	CDD:275380	8/22 (36%)
		LRR_8	272..329	CDD:290566	17/58 (29%)
		leucine-rich repeat	273..295	CDD:275380	7/22 (32%)
		leucine-rich repeat	296..318	CDD:275380	5/22 (23%)
		LRR_8	317..375	CDD:290566	19/59 (32%)
		leucine-rich repeat	319..340	CDD:275380	6/22 (27%)
		leucine-rich repeat	341..364	CDD:275380	7/22 (32%)
		leucine-rich repeat	389..410	CDD:275380	6/21 (29%)
		leucine-rich repeat	411..430	CDD:275380	5/18 (28%)
		leucine-rich repeat	627..650	CDD:275380
		leucine-rich repeat	651..669	CDD:275380
		leucine-rich repeat	697..719	CDD:275380
		LRR_8	719..777	CDD:290566
		leucine-rich repeat	720..743	CDD:275380
		leucine-rich repeat	744..766	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910