DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7509 and chad

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_957357.1	Gene:	chad / 394038	ZFINID:	ZDB-GENE-040426-1130	Length:	363	Species:	Danio rerio

Alignment Length:	393	Identity:	94/393 - (23%)
Similarity:	150/393 - (38%)	Gaps:	84/393 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 CRCNPDTKSFTCWNTNLKSVPVTQVIPMNMVNIDLSRNILSTLHKDTFRGLTVLKELDISHNVLD 218
            |.|:.|.:...|.|..||.:|                           |.....:.|::..|.|.
Zfish    31 CHCHGDLQHVICDNVGLKKIP---------------------------RISEATRLLNLQRNNLG 68

  Fly   219 FLPFDLFQDLDSLLVLRIQNNQLEDIDHRTFWKLRNLNILDLSKNEIGMLPESIFYHAQRLTVIN 283
            .||...|.::..|:.|.:|:.|:.::..:.|..|..|..|.||.|||..:....|.....||.:.
Zfish    69 NLPTGGFSEMKGLISLHLQHCQIRELSGQAFKGLNKLIYLYLSDNEISTIKPGAFEDLTELTYLY 133

  Fly   284 MCDNQIQNFPPNLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDDFFAGL 348
            :..|||.:.|..:....:.|..|.::.||:.||..|:                        |.|.
Zfish   134 LDGNQITSLPKGIFSPMINLFILQLNNNKLRELQPGT------------------------FKGA 174

  Fly   349 RSLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSIP 413
            :.||.|.:..|.:||:.....:.:.||..|.|..|.:|.....|..:|..:.||.|.:|.:|.||
Zfish   175 KDLRWLYMSGNELSSIQPGSLDEVENLAILTLDQNNLSTYPLLAMSKLRVVEELNLSKNPLSLIP 239

  Fly   414 ADLFLNVSALTRLTLFSNNLTTLEADDFQGLNNLKILLLNNNILKNFDARAFEPLSQLEKLRIDS 478
            ...|.:         |...:..|.              ||:..|:.|...|||.::.|:.|.:::
Zfish   240 DHAFRS---------FGRYMEKLH--------------LNDMSLEKFSNAAFEGVTALKSLHLEN 281

  Fly   479 NKLMFLPHGALHGLKNLVAVKLDKNPWHCDCRALYLARWIREFVLKLWDGQQP--MCRGPGDLGG 541
            |||..||:..  ....:..:.|..|||.|.|....|.:|:..      ...:|  :|..|.:..|
Zfish   282 NKLRSLPNSL--EFSTIQNITLFNNPWSCTCPLTNLRKWMDT------TRNRPDAVCASPANQKG 338

  Fly   542 HEV 544
            .::
Zfish   339 KQI 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	10/58 (17%)
		leucine-rich repeat	187..206	CDD:275380	1/18 (6%)
		LRR_RI	<201..386	CDD:238064	47/184 (26%)
		leucine-rich repeat	207..230	CDD:275380	6/22 (27%)
		leucine-rich repeat	231..254	CDD:275380	6/22 (27%)
		LRR_8	253..313	CDD:290566	17/59 (29%)
		leucine-rich repeat	255..278	CDD:275380	8/22 (36%)
		leucine-rich repeat	279..302	CDD:275380	6/22 (27%)
		LRR_8	303..361	CDD:290566	13/57 (23%)
		leucine-rich repeat	303..326	CDD:275380	7/22 (32%)
		leucine-rich repeat	327..350	CDD:275380	2/22 (9%)
		LRR_8	349..407	CDD:290566	17/57 (30%)
		LRR_4	350..390	CDD:289563	12/39 (31%)
		leucine-rich repeat	351..374	CDD:275380	6/22 (27%)
		leucine-rich repeat	375..398	CDD:275380	7/22 (32%)
		LRR_8	398..>443	CDD:290566	10/44 (23%)
		leucine-rich repeat	399..422	CDD:275380	8/22 (36%)
		leucine-rich repeat	423..443	CDD:275380	2/19 (11%)
		leucine-rich repeat	471..494	CDD:275380	7/22 (32%)
		LRRCT	503..554	CDD:214507	11/44 (25%)
chad	NP_957357.1	LRRNT	26..52	CDD:279764	8/47 (17%)
		leucine-rich repeat	57..80	CDD:275380	6/22 (27%)
		LRR_8	79..139	CDD:290566	17/59 (29%)
		leucine-rich repeat	81..104	CDD:275380	6/22 (27%)
		LRR_RI	<96..304	CDD:238064	64/256 (25%)
		LRR_4	104..143	CDD:289563	13/38 (34%)
		leucine-rich repeat	105..128	CDD:275380	8/22 (36%)
		LRR_8	127..187	CDD:290566	19/83 (23%)
		leucine-rich repeat	129..152	CDD:275380	6/22 (27%)
		leucine-rich repeat	153..176	CDD:275380	9/46 (20%)
		LRR_8	177..235	CDD:290566	18/57 (32%)
		leucine-rich repeat	177..200	CDD:275380	6/22 (27%)
		leucine-rich repeat	201..224	CDD:275380	7/22 (32%)
		LRR_8	225..284	CDD:290566	20/81 (25%)
		leucine-rich repeat	225..248	CDD:275380	9/31 (29%)
		leucine-rich repeat	250..273	CDD:275380	8/36 (22%)
		LRRCT	304..351	CDD:214507	11/44 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910