DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG7509 and CG6749

DIOPT Version :9

Sequence 1:NP_647931.1 Gene:CG7509 / 38579 FlyBaseID:FBgn0035575 Length:615 Species:Drosophila melanogaster
Sequence 2:NP_648354.1 Gene:CG6749 / 39144 FlyBaseID:FBgn0036040 Length:552 Species:Drosophila melanogaster


Alignment Length:563 Identity:138/563 - (24%)
Similarity:204/563 - (36%) Gaps:176/563 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   135 VWHLATGSQIEWNHCTSGVCRCNP-DTKSFTC----------------WNT-------------- 168
            :|.|..|..|     ..|...|.| ..::|.|                |:|              
  Fly    13 LWLLCMGFPI-----LHGADLCQPIGWRNFQCSEVASLQDLVDLGAENWHTLAIRNVQTELEVGS 72

  Fly   169 --------NLKSVPVTQVIPMN-----------------------------------MVNIDLSR 190
                    ||..:.:|...|:|                                   :..||.|.
  Fly    73 GENADHLANLLDLDLTGAAPINVHTNGFSILPNLRQLNLSGCGLVDIRGNHFAPESALQRIDFSH 137

  Fly   191 NILSTLHKDTFRGL----------TVLKELDISH------------------------------- 214
            |.:..|.:|.|..|          ..||:.|:.|                               
  Fly   138 NQMELLDRDFFGNLRKLIYANFSHNALKQCDLPHMPLLNRLELGHNRLVNATFGVCPQLQELILN 202

  Fly   215 -NVLDFLPFDLFQDLDSLLVLRIQNNQLEDIDHRTFWKLRNLNILDLSKNEIGMLPESIFYHAQR 278
             |.|..|..:.|:.|..||.|::..|:|..|...||..|..|..|:||:|.:..|..::|     
  Fly   203 DNQLIQLDVNAFRGLHGLLELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVF----- 262

  Fly   279 LTVINMCDNQIQNFPPNLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDD 343
                    ..:|||       .|.|::||:|.|:|..|.....|.|.:|:.||...|.||.:...
  Fly   263 --------GAVQNF-------VLHLQQLDLSGNRIRLLFDNQFRVLARLQMLDVSRNSIASLSPA 312

  Fly   344 FFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHID-----GNAFVELNNLNELF 403
            .|.||.|||.|.|..|.|..:....|..|.||.||||:.|.:..::     ||....:..||   
  Fly   313 HFVGLGSLRKLYLQYNAILEIKPATFAALLNLDTLDLSYNNLEFLEEQIFGGNTLPRMRRLN--- 374

  Fly   404 LGQNSMSSIPADLFLNVSALTRLTLFSNNLTTLEADDFQGLNNLKILLLNNNILKNFDARAFEPL 468
            |..|.|..:....|.::..|..|.|..|.|.:|:...|..:..|:.|.|.:|:|:..:....|.|
  Fly   375 LNGNRMKHLHPLAFSSLPFLEYLKLGHNELKSLDVRMFAPMRRLQKLHLGHNLLEEINLDVLESL 439

  Fly   469 SQLEKLRIDSNKLMFLPHGALHGLKNLVAVKLDKNPWHCDCRALYLARWI--REFV-----LKLW 526
            |.::::.:|:|:|.||....: ...||..|.::.|||.|.| .:.|..|:  |:.|     ...:
  Fly   440 SSVQEILVDNNRLTFLAKVNV-SFPNLKRVAIEGNPWQCPC-FVKLQHWLATRDVVYLRDNTGYY 502

  Fly   527 DGQQPMC---------------RGPGDLG---GHEVGLLRYDD 551
            .|::|:|               |..|.||   |.:|....:||
  Fly   503 KGERPLCIVTNVDYCIQNLQAVRRLGILGDFQGEQVEADAFDD 545

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7509NP_647931.1 LRR_8 182..241 CDD:290566 22/135 (16%)
leucine-rich repeat 187..206 CDD:275380 7/28 (25%)
LRR_RI <201..386 CDD:238064 65/226 (29%)
leucine-rich repeat 207..230 CDD:275380 9/54 (17%)
leucine-rich repeat 231..254 CDD:275380 9/22 (41%)
LRR_8 253..313 CDD:290566 16/59 (27%)
leucine-rich repeat 255..278 CDD:275380 7/22 (32%)
leucine-rich repeat 279..302 CDD:275380 3/22 (14%)
LRR_8 303..361 CDD:290566 24/57 (42%)
leucine-rich repeat 303..326 CDD:275380 9/22 (41%)
leucine-rich repeat 327..350 CDD:275380 9/22 (41%)
LRR_8 349..407 CDD:290566 21/62 (34%)
LRR_4 350..390 CDD:289563 16/44 (36%)
leucine-rich repeat 351..374 CDD:275380 8/22 (36%)
leucine-rich repeat 375..398 CDD:275380 8/27 (30%)
LRR_8 398..>443 CDD:290566 13/44 (30%)
leucine-rich repeat 399..422 CDD:275380 6/22 (27%)
leucine-rich repeat 423..443 CDD:275380 7/19 (37%)
leucine-rich repeat 471..494 CDD:275380 5/22 (23%)
LRRCT 503..554 CDD:214507 20/74 (27%)
CG6749NP_648354.1 LRR_RI 103..>256 CDD:238064 31/152 (20%)
LRR_8 104..164 CDD:290566 8/59 (14%)
leucine-rich repeat 106..129 CDD:275380 0/22 (0%)
leucine-rich repeat 130..153 CDD:275380 8/22 (36%)
leucine-rich repeat 154..195 CDD:275380 4/40 (10%)
LRR_RI 194..455 CDD:238064 85/283 (30%)
LRR_8 194..254 CDD:290566 19/59 (32%)
leucine-rich repeat 196..219 CDD:275380 5/22 (23%)
leucine-rich repeat 220..243 CDD:275380 9/22 (41%)
leucine-rich repeat 244..267 CDD:275380 7/35 (20%)
LRR_8 271..330 CDD:290566 24/58 (41%)
leucine-rich repeat 272..295 CDD:275380 9/22 (41%)
leucine-rich repeat 296..319 CDD:275380 9/22 (41%)
LRR_8 319..380 CDD:290566 22/63 (35%)
leucine-rich repeat 320..343 CDD:275380 8/22 (36%)
leucine-rich repeat 344..369 CDD:275380 8/24 (33%)
LRR_8 368..428 CDD:290566 17/62 (27%)
leucine-rich repeat 370..393 CDD:275380 6/25 (24%)
leucine-rich repeat 394..417 CDD:275380 7/22 (32%)
leucine-rich repeat 418..441 CDD:275380 7/22 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 56 1.000 Inparanoid score I440
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.960

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