DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7509 and Lrt

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_001286640.1	Gene:	Lrt / 37342	FlyBaseID:	FBgn0034540	Length:	830	Species:	Drosophila melanogaster

Alignment Length:	550	Identity:	120/550 - (21%)
Similarity:	198/550 - (36%)	Gaps:	160/550 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 KRVRQIESRLRSVEQ------PV------WHL--ATG---SQIEWNHCTSGVCRCNPDTKSFTCW 166
            |.|.:...|.|..||      ||      |..  .||   :::|.........|||.|.......
  Fly   101 KYVNKSSPRKRKAEQVSSLPLPVDDALMEWKCPNITGTRNAELECGCDLPHTLRCNIDLHGMMLL 165

  Fly   167 NTNLKSVPVT-QVIPMNMVNID-----------------LSRNILSTLHKDTFRG---------- 203
            ...|::.|.: .::..::.|:.                 :|...:..:||..|.|
  Fly   166 ADRLRTSPYSISLLDCSLRNVTFLSDAKIFDNVSLHGLVISSGEIKRVHKSAFLGIRGPLQALGL 230

  Fly   204 ---------------LTVLKELDISHNVLDFLPFDLFQDLDSLLVLRIQNNQLEDIDHRTFWKLR 253
                           |:.|:.||:::|.:..|....|..|.||:.|.:.|||:..|..|||..||
  Fly   231 PGNALMSVPWNALSTLSALERLDLANNKIKALGTADFVGLTSLVYLELSNNQISSISQRTFVNLR 295

  Fly   254 NLNILDLSKNEIGMLPESIFYHAQRLTVINMCDNQIQNFPPNLLRDQLMLEELDMSRNKISELSS 318
            .|.:|.|..|.:|       .:||.|..::.|               |.|.:||:..|.::
  Fly   296 KLEVLKLGGNRLG-------DYAQSLRSLSQC---------------LSLRQLDLQANNLN---- 334

  Fly   319 GSIRYLTKLKTLDFGWNQIAKIDDDFFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTN 383
                               ..:.:....|:|:|.:|:|:.|.|.|:......|.:.||:|.|..|
  Fly   335 -------------------GPLSEQTLPGMRNLESLNLNRNLIKSIQNKALANFSRLVSLSLRHN 380

  Fly   384 RISHIDGNAFVELNNLNELFLGQNSMSSIPADLFLNVSALTRLTLFSNNLTTLEADDFQGLNNLK 448
            :|..:..:|                        |..:.||..|.|..|.:..:.:...|.|:.|.
  Fly   381 QIDVLQDHA------------------------FFGLGALDSLDLSYNGIVAISSASLQHLSRLT 421

  Fly   449 ILLLNNNILKNFDARAFEPLSQLEKLRIDSNKLMFLPHGALHGLKNLVAVKLDKNPWHCDCRALY 513
            :|.|.:|.|:...:....||..|.:||:..|.:..:...|:.|.:.|.::::.:||..|||....
  Fly   422 VLDLTHNFLRALTSDLIAPLPSLRELRLAGNDISIVARNAMDGARELESLQMQENPLSCDCSIRP 486

  Fly   514 LARWIREFVLKLWDGQQPMCRGPGDLGGHEVGLLRYDDLCDGQWASMLSLSPRLPVRKHQISTPM 578
            .|.|::|  .:|.......|..|..|.|                      :|.|.|....:|..|
  Fly   487 FAEWLQE--SQLHSSLSASCVTPPRLEG----------------------APLLQVPVETLSCDM 527

  Fly   579 NYTDYFNL-YLKHIYNGTTDEELKEADITS 607
            :..:..|. .::|:      |.|.:.:.||
  Fly   528 DNVEKDNANIMQHL------ETLAKPNQTS 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	19/100 (19%)
		leucine-rich repeat	187..206	CDD:275380	6/60 (10%)
		LRR_RI	<201..386	CDD:238064	50/209 (24%)
		leucine-rich repeat	207..230	CDD:275380	7/22 (32%)
		leucine-rich repeat	231..254	CDD:275380	10/22 (45%)
		LRR_8	253..313	CDD:290566	15/59 (25%)
		leucine-rich repeat	255..278	CDD:275380	6/22 (27%)
		leucine-rich repeat	279..302	CDD:275380	2/22 (9%)
		LRR_8	303..361	CDD:290566	10/57 (18%)
		leucine-rich repeat	303..326	CDD:275380	4/22 (18%)
		leucine-rich repeat	327..350	CDD:275380	1/22 (5%)
		LRR_8	349..407	CDD:290566	15/57 (26%)
		LRR_4	350..390	CDD:289563	13/39 (33%)
		leucine-rich repeat	351..374	CDD:275380	7/22 (32%)
		leucine-rich repeat	375..398	CDD:275380	7/22 (32%)
		LRR_8	398..>443	CDD:290566	6/44 (14%)
		leucine-rich repeat	399..422	CDD:275380	1/22 (5%)
		leucine-rich repeat	423..443	CDD:275380	4/19 (21%)
		leucine-rich repeat	471..494	CDD:275380	6/22 (27%)
		LRRCT	503..554	CDD:214507	13/50 (26%)
Lrt	NP_001286640.1	LRR_RI	<151..334	CDD:238064	46/204 (23%)
		leucine-rich repeat	179..199	CDD:275378	1/19 (5%)
		leucine-rich repeat	200..223	CDD:275380	5/22 (23%)
		leucine-rich repeat	225..248	CDD:275380	1/22 (5%)
		LRR_8	249..307	CDD:290566	23/57 (40%)
		leucine-rich repeat	249..272	CDD:275380	7/22 (32%)
		LRR_RI	<270..479	CDD:238064	67/277 (24%)
		leucine-rich repeat	273..296	CDD:275380	10/22 (45%)
		leucine-rich repeat	297..322	CDD:275380	9/46 (20%)
		LRR_8	322..382	CDD:290566	18/82 (22%)
		leucine-rich repeat	323..347	CDD:275380	5/46 (11%)
		leucine-rich repeat	348..371	CDD:275380	7/22 (32%)
		LRR_8	370..428	CDD:290566	18/81 (22%)
		leucine-rich repeat	372..395	CDD:275380	8/46 (17%)
		leucine-rich repeat	396..419	CDD:275380	6/22 (27%)
		LRR_8	418..478	CDD:290566	15/59 (25%)
		leucine-rich repeat	420..443	CDD:275380	7/22 (32%)
		leucine-rich repeat	444..467	CDD:275380	6/22 (27%)
		LRRCT	476..526	CDD:214507	17/73 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910