DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7509 and CG8852

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_608790.2	Gene:	CG8852 / 33577	FlyBaseID:	FBgn0031548	Length:	663	Species:	Drosophila melanogaster

Alignment Length:	519	Identity:	114/519 - (21%)
Similarity:	196/519 - (37%)	Gaps:	170/519 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 SLNACESLGIVSQLLMLINSMPNGTQSAAND--KKPP---------KSKANGHNDGD------VN 102
            ::..|..|.:|||:|..:.: .....|:||:  ..||         |:.::..:..|      ::
  Fly     9 AMTQCVFLVVVSQILSHVRA-AGDAMSSANESISLPPACVIRATLYKTSSSERSQNDFGLPLAID 72

  Fly   103 GGEINAMSHLANFDL-VKRV---RQIESRLRSVEQPVWHLATGSQIEWNHCTSGVCRCNPDTKSF 163
            ..|.::|. :..||| .:||   |.:.  |...:.|...:::......::|
  Fly    73 CSENSSMG-MNYFDLGAQRVAGKRHVS--LDGFQTPPLGISSYGLEYLDNC-------------- 120

  Fly   164 TCWNTNLKSVPVTQ--------------VIPMNMVNIDLSRNILSTLHKDTFRGLTVLKELDISH 214
                .:|:||.:.:              :|| |:..:....|.|.||..:|.:.|..||.|.:..
  Fly   121 ----VDLESVEIQRFVGDATLKLSCGGALIP-NLTAVSFRYNELGTLSGETIQDLPHLKILHLQQ 180

  Fly   215 NVLDFLP-FDLFQDLDSL-------LVLRIQN--NQLEDIDHRTFWKLRNLNILDLSKNE---IG 266
            |.|.:|. |....||:.|       ||||...  |||.:        ||.|::.::.|.|   :.
  Fly   181 NSLRYLEYFKEHSDLEELLIQDERDLVLRFNEILNQLPE--------LRRLSLRNVEKIEDQFLR 237

  Fly   267 MLPESIFYHAQRLTVINMCDNQIQNFP--PNLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKT 329
            :|||            |:.|..|:|.|  |.:    |.|.|      .:::|.:.:|   |..:.
  Fly   238 ILPE------------NLTDLIIENTPIQPGV----LYLTE------GVAKLVNVTI---TNCQL 277

  Fly   330 LDFGWNQIAKIDDDFFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFV 394
            ..|.......:|         :..|:|..|.||||:.:..:..:.|:||||:.||:.|::...|.
  Fly   278 KGFALQPAHNLD---------IMYLNLSGNAISSLNISFESGPSTLLTLDLSRNRLEHLNFTWFY 333

  Fly   395 ELNNLNELFLGQNSMSSIPADL--FLNVSALTRLTLFSNNLTTLEADDFQGLNNLKILLLNNNIL 457
            ...:|..|.|.:|...|:....  |::.:::..:.|.||.|.:....:
  Fly   334 RTTSLRSLHLQENHFHSLSLFQLGFISSASIHHIDLRSNELMSFRDTE----------------- 381

  Fly   458 KNFDARAFEPLSQLEKLRIDSNKLMFLPHGALHGLKNLVAVKLDKNPWHCDCRALYLARWIREF 521
             |.|..::.|     :|||                      .:|.|||.|        :|:..|
  Fly   382 -NADLPSWNP-----QLRI----------------------SIDDNPWSC--------QWMLNF 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	22/68 (32%)
		leucine-rich repeat	187..206	CDD:275380	6/18 (33%)
		LRR_RI	<201..386	CDD:238064	54/199 (27%)
		leucine-rich repeat	207..230	CDD:275380	9/23 (39%)
		leucine-rich repeat	231..254	CDD:275380	9/31 (29%)
		LRR_8	253..313	CDD:290566	16/64 (25%)
		leucine-rich repeat	255..278	CDD:275380	6/25 (24%)
		leucine-rich repeat	279..302	CDD:275380	6/24 (25%)
		LRR_8	303..361	CDD:290566	10/57 (18%)
		leucine-rich repeat	303..326	CDD:275380	4/22 (18%)
		leucine-rich repeat	327..350	CDD:275380	2/22 (9%)
		LRR_8	349..407	CDD:290566	19/57 (33%)
		LRR_4	350..390	CDD:289563	15/39 (38%)
		leucine-rich repeat	351..374	CDD:275380	7/22 (32%)
		leucine-rich repeat	375..398	CDD:275380	9/22 (41%)
		LRR_8	398..>443	CDD:290566	10/46 (22%)
		leucine-rich repeat	399..422	CDD:275380	6/24 (25%)
		leucine-rich repeat	423..443	CDD:275380	4/19 (21%)
		leucine-rich repeat	471..494	CDD:275380	3/22 (14%)
		LRRCT	503..554	CDD:214507	6/19 (32%)
CG8852	NP_608790.2	LRR_RI	114..348	CDD:238064	72/294 (24%)
		LRR_8	147..213	CDD:290566	22/66 (33%)
		leucine-rich repeat	149..172	CDD:275380	6/22 (27%)
		leucine-rich repeat	173..194	CDD:275380	7/20 (35%)
		leucine-rich repeat	220..242	CDD:275380	8/33 (24%)
		leucine-rich repeat	243..266	CDD:275380	8/32 (25%)
		leucine-rich repeat	267..287	CDD:275380	4/22 (18%)
		leucine-rich repeat	288..313	CDD:275380	8/33 (24%)
		LRR_8	291..348	CDD:290566	20/56 (36%)
		leucine-rich repeat	314..337	CDD:275380	9/22 (41%)
		leucine-rich repeat	364..387	CDD:275378	6/40 (15%)
		leucine-rich repeat	392..403	CDD:275378	7/32 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438687
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840