DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7509 and AgaP_AGAP010804

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	XP_554237.3	Gene:	AgaP_AGAP010804 / 3291171	VectorBaseID:	AGAP010804	Length:	452	Species:	Anopheles gambiae

Alignment Length:	329	Identity:	88/329 - (26%)
Similarity:	151/329 - (45%)	Gaps:	44/329 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 LSRNILSTLHKDTFRGLTVLKELDISHNVLDFLPFDLFQDLDSLLVLRIQNNQLEDIDHRTFWKL 252
            |..|:|:||:.:.|.....::.|::..|.:..: ...|:...||.:| :..|:|..||. ..|.:
Mosquito   103 LPNNLLTTLNMEIFNHFGKIQMLEVKQNRIKAV-LGRFESTASLQLL-LSKNKLTSIDF-CGWNV 164

  Fly   253 RNLNILDLSKNEIGMLPESIFYHAQRLTVINMCDNQIQNFPPNLLRDQLMLEELDMSRNKISELS 317
            .|:..|::..||:..:| :...:...||::::..|:|||...:.......|..||:|.|.::.:.
Mosquito   165 SNMTSLEMDYNELTTVP-ACLDNVNSLTLLSIRTNRIQNVAIDSFAKLKRLVTLDVSFNNLTTIM 228

  Fly   318 SGSIRYLTKLKTLDFGWNQIAKIDDDFFAGLRSLRTLSL--HNNRISSLS--------------- 365
            ..|..|.|.|:.|....|.::::|    ..|.|:.:|.|  ..|.|||:.
Mosquito   229 LNSPHYPTSLRDLWITGNNLSQLD----LSLVSVPSLELDVRMNCISSMDVDSISPNITKLNMAA 289

  Fly   366 -------GTIFNNLANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSIPADLFL--NVS 421
                   .||||:...:..|::..|||..:.|. |....:| :|.|.:|.::||.   |.  |||
Mosquito   290 NPIDCSWKTIFNHFGKIQMLEVKQNRIKAVLGR-FESTASL-QLLLSKNKLTSID---FCGWNVS 349

  Fly   422 ALTRLTLFSNNLTTLEADDFQGLNNLKILLLNNNILKNFDARAFEPLSQLEKLRIDSNKLMFL-- 484
            .:|.|.:..|.|||:.| ....:|:|.:|.:..|.::|....:|..|.:|..|.:..|.|..:
Mosquito   350 NMTSLEMDYNELTTVPA-CLDNVNSLTLLSIRTNRIQNVAIDSFAKLKRLVTLDVSFNNLTTIML 413

  Fly   485 --PH 486
              ||
Mosquito   414 NSPH 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566	13/52 (25%)
		leucine-rich repeat	187..206	CDD:275380	6/17 (35%)
		LRR_RI	<201..386	CDD:238064	50/208 (24%)
		leucine-rich repeat	207..230	CDD:275380	3/22 (14%)
		leucine-rich repeat	231..254	CDD:275380	7/22 (32%)
		LRR_8	253..313	CDD:290566	16/59 (27%)
		leucine-rich repeat	255..278	CDD:275380	4/22 (18%)
		leucine-rich repeat	279..302	CDD:275380	6/22 (27%)
		LRR_8	303..361	CDD:290566	17/59 (29%)
		leucine-rich repeat	303..326	CDD:275380	7/22 (32%)
		leucine-rich repeat	327..350	CDD:275380	5/22 (23%)
		LRR_8	349..407	CDD:290566	20/81 (25%)
		LRR_4	350..390	CDD:289563	15/63 (24%)
		leucine-rich repeat	351..374	CDD:275380	10/46 (22%)
		leucine-rich repeat	375..398	CDD:275380	6/22 (27%)
		LRR_8	398..>443	CDD:290566	17/46 (37%)
		leucine-rich repeat	399..422	CDD:275380	9/24 (38%)
		leucine-rich repeat	423..443	CDD:275380	7/19 (37%)
		leucine-rich repeat	471..494	CDD:275380	6/20 (30%)
		LRRCT	503..554	CDD:214507
AgaP_AGAP010804	XP_554237.3	leucine-rich repeat	71..97	CDD:275380
		leucine-rich repeat	98..121	CDD:275380	6/17 (35%)
		leucine-rich repeat	122..144	CDD:275380	3/22 (14%)
		leucine-rich repeat	145..166	CDD:275380	7/22 (32%)
		leucine-rich repeat	167..189	CDD:275380	4/22 (18%)
		LRR_8	189..248	CDD:290566	17/58 (29%)
		leucine-rich repeat	190..213	CDD:275380	6/22 (27%)
		leucine-rich repeat	214..237	CDD:275380	7/22 (32%)
		leucine-rich repeat	238..260	CDD:275380	6/25 (24%)
		leucine-rich repeat	283..294	CDD:275378	0/10 (0%)
		leucine-rich repeat	306..320	CDD:275380	4/13 (31%)
		leucine-rich repeat	329..350	CDD:275380	9/24 (38%)
		leucine-rich repeat	351..373	CDD:275380	7/22 (32%)
		LRR_8	373..432	CDD:290566	12/45 (27%)
		leucine-rich repeat	374..397	CDD:275380	6/22 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910