DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7509 and AgaP_AGAP007470

DIOPT Version :9

Sequence 1:	NP_647931.1	Gene:	CG7509 / 38579	FlyBaseID:	FBgn0035575	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	XP_564789.2	Gene:	AgaP_AGAP007470 / 3290374	VectorBaseID:	AGAP007470	Length:	334	Species:	Anopheles gambiae

Alignment Length:	263	Identity:	62/263 - (23%)
Similarity:	111/263 - (42%)	Gaps:	46/263 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   278 RLTVINMCDNQIQNF-----PPNLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQI 337
            :||.|::..|:|:..     ||   :.:|.:..|.:..|::..|......::.||:..|...|:|
Mosquito    82 KLTTIDLTRNRIRQLFPITTPP---KTKLSVTSLSLVANQLEHLDMSMFAFMPKLELFDVRGNRI 143

  Fly   338 AKID-----DDFFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTNRISHIDGNAFVELN 397
            .:::     |.....|..||:|.:.:|.::.|. |.:..|.|||.|....|.:..||.:.|.:..
Mosquito   144 VRLEATAPFDTRNLTLPVLRSLYIDDNALTELP-THWGKLPNLVYLGFDRNYLKRIDISFFGKFP 207

  Fly   398 NLNELFLGQNSMSSIPADLFLNVSALTRLTLFSNNLTTLEADDFQGLN--NLKILLLNNNILKNF 460
            .||.:|:.:|::.:|.....:.:..|..:...||.:.::   :|.|.|  .:.|:.|.||.|
Mosquito   208 TLNAIFICENNVETIRTSTPITMPELDIMLFESNQIVSV---NFTGCNFPKMNIISLMNNRL--- 266

  Fly   461 DARAFEPLSQLEKLRIDSNKLMFLPHGALHGLKNLVAVKLDKNPWHCDCRALYLARWIREFVLKL 525
              ....||.|    |...::|                 .::.||..| |........|.:|.|::
Mosquito   267 --TTIPPLFQ----RFSESRL-----------------TMEGNPIKC-CNMTVFKSKITDFQLRV 307

  Fly   526 WDG 528
            ..|
Mosquito   308 TTG 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7509	NP_647931.1	LRR_8	182..241	CDD:290566
		leucine-rich repeat	187..206	CDD:275380
		LRR_RI	<201..386	CDD:238064	30/117 (26%)
		leucine-rich repeat	207..230	CDD:275380
		leucine-rich repeat	231..254	CDD:275380
		LRR_8	253..313	CDD:290566	10/39 (26%)
		leucine-rich repeat	255..278	CDD:275380	62/263 (24%)
		leucine-rich repeat	279..302	CDD:275380	7/27 (26%)
		LRR_8	303..361	CDD:290566	14/62 (23%)
		leucine-rich repeat	303..326	CDD:275380	3/22 (14%)
		leucine-rich repeat	327..350	CDD:275380	6/27 (22%)
		LRR_8	349..407	CDD:290566	18/57 (32%)
		LRR_4	350..390	CDD:289563	13/39 (33%)
		leucine-rich repeat	351..374	CDD:275380	7/22 (32%)
		leucine-rich repeat	375..398	CDD:275380	7/22 (32%)
		LRR_8	398..>443	CDD:290566	9/44 (20%)
		leucine-rich repeat	399..422	CDD:275380	5/22 (23%)
		leucine-rich repeat	423..443	CDD:275380	4/19 (21%)
		leucine-rich repeat	471..494	CDD:275380	2/22 (9%)
		LRRCT	503..554	CDD:214507	8/26 (31%)
AgaP_AGAP007470	XP_564789.2	leucine-rich repeat	59..82	CDD:275380	62/263 (24%)
		leucine-rich repeat	83..106	CDD:275380	7/25 (28%)
		leucine-rich repeat	107..132	CDD:275380	4/24 (17%)
		LRR_8	108..172	CDD:290566	14/63 (22%)
		leucine-rich repeat	133..156	CDD:275380	5/22 (23%)
		LRR_8	160..>204	CDD:290566	14/44 (32%)
		leucine-rich repeat	162..184	CDD:275380	7/22 (32%)
		leucine-rich repeat	185..208	CDD:275380	7/22 (32%)
		leucine-rich repeat	209..232	CDD:275380	5/22 (23%)
		leucine-rich repeat	233..255	CDD:275380	6/24 (25%)
		leucine-rich repeat	256..278	CDD:275380	9/30 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910